| Dataset | CMP.CMP_Pheno.cls#Group6_versus_Group8.CMP_Pheno.cls#Group6_versus_Group8_repos |
| Phenotype | CMP_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 4 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.123008385 |
| Normalized Enrichment Score (NES) | 0.52220076 |
| Nominal p-value | 0.9361277 |
| FDR q-value | 0.9883075 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Donson | 443 | 0.583 | -0.0046 | Yes |
| 2 | Pttg1 | 761 | 0.510 | -0.0050 | Yes |
| 3 | Ube2s | 788 | 0.504 | 0.0092 | Yes |
| 4 | Aurka | 826 | 0.495 | 0.0226 | Yes |
| 5 | Kif2c | 834 | 0.493 | 0.0375 | Yes |
| 6 | Pop7 | 922 | 0.471 | 0.0476 | Yes |
| 7 | Wdr90 | 949 | 0.466 | 0.0606 | Yes |
| 8 | Mxd3 | 968 | 0.462 | 0.0740 | Yes |
| 9 | Dlgap5 | 1195 | 0.433 | 0.0758 | Yes |
| 10 | Kif18b | 1488 | 0.410 | 0.0736 | Yes |
| 11 | Dck | 1730 | 0.390 | 0.0733 | Yes |
| 12 | Cdkn3 | 1804 | 0.381 | 0.0814 | Yes |
| 13 | Mki67 | 1921 | 0.365 | 0.0867 | Yes |
| 14 | Spag5 | 2393 | 0.314 | 0.0723 | Yes |
| 15 | Cdkn2c | 2566 | 0.299 | 0.0728 | Yes |
| 16 | Ing3 | 2659 | 0.294 | 0.0772 | Yes |
| 17 | Bard1 | 2801 | 0.283 | 0.0787 | Yes |
| 18 | Cdc25b | 3160 | 0.263 | 0.0685 | Yes |
| 19 | Nup205 | 3168 | 0.262 | 0.0763 | Yes |
| 20 | Cenpe | 3287 | 0.258 | 0.0782 | Yes |
| 21 | Tacc3 | 3501 | 0.252 | 0.0751 | Yes |
| 22 | Depdc1a | 3593 | 0.247 | 0.0781 | Yes |
| 23 | Pold2 | 3614 | 0.246 | 0.0847 | Yes |
| 24 | Hus1 | 3687 | 0.241 | 0.0884 | Yes |
| 25 | Kif4 | 3803 | 0.234 | 0.0898 | Yes |
| 26 | Plk4 | 4290 | 0.215 | 0.0716 | Yes |
| 27 | Hmmr | 4346 | 0.212 | 0.0754 | Yes |
| 28 | Bub1b | 4410 | 0.208 | 0.0786 | Yes |
| 29 | Cks2 | 4568 | 0.198 | 0.0767 | Yes |
| 30 | Pold1 | 4638 | 0.195 | 0.0791 | Yes |
| 31 | Xpo1 | 4829 | 0.187 | 0.0752 | Yes |
| 32 | Pnn | 4934 | 0.182 | 0.0755 | Yes |
| 33 | Diaph3 | 5080 | 0.174 | 0.0735 | Yes |
| 34 | Cit | 5105 | 0.173 | 0.0776 | Yes |
| 35 | Aurkb | 5115 | 0.173 | 0.0825 | Yes |
| 36 | Dscc1 | 5121 | 0.172 | 0.0875 | Yes |
| 37 | Cdkn2a | 5139 | 0.171 | 0.0919 | Yes |
| 38 | Top2a | 5168 | 0.170 | 0.0957 | Yes |
| 39 | Shmt1 | 5200 | 0.168 | 0.0994 | Yes |
| 40 | Rad21 | 5249 | 0.166 | 0.1020 | Yes |
| 41 | Cdk1 | 5269 | 0.165 | 0.1061 | Yes |
| 42 | Cnot9 | 5502 | 0.154 | 0.0990 | Yes |
| 43 | Pole | 5506 | 0.154 | 0.1036 | Yes |
| 44 | Lmnb1 | 5661 | 0.148 | 0.1004 | Yes |
| 45 | Hells | 5706 | 0.146 | 0.1026 | Yes |
| 46 | Kif22 | 5847 | 0.140 | 0.0998 | Yes |
| 47 | Cdkn1b | 5894 | 0.138 | 0.1017 | Yes |
| 48 | Ccne1 | 6003 | 0.134 | 0.1003 | Yes |
| 49 | Asf1b | 6039 | 0.132 | 0.1026 | Yes |
| 50 | Pola2 | 6130 | 0.128 | 0.1020 | Yes |
| 51 | Tra2b | 6134 | 0.128 | 0.1058 | Yes |
| 52 | Nasp | 6159 | 0.127 | 0.1084 | Yes |
| 53 | Ezh2 | 6181 | 0.126 | 0.1113 | Yes |
| 54 | Brca2 | 6210 | 0.125 | 0.1137 | Yes |
| 55 | Mlh1 | 6236 | 0.124 | 0.1162 | Yes |
| 56 | Dnmt1 | 6376 | 0.118 | 0.1128 | Yes |
| 57 | Espl1 | 6404 | 0.117 | 0.1150 | Yes |
| 58 | Cse1l | 6449 | 0.116 | 0.1163 | Yes |
| 59 | Prkdc | 6471 | 0.115 | 0.1188 | Yes |
| 60 | Ilf3 | 6563 | 0.112 | 0.1176 | Yes |
| 61 | Mcm4 | 6565 | 0.112 | 0.1210 | Yes |
| 62 | Tipin | 6594 | 0.111 | 0.1230 | Yes |
| 63 | Lbr | 6750 | 0.105 | 0.1183 | No |
| 64 | Melk | 6837 | 0.101 | 0.1171 | No |
| 65 | Spc25 | 6964 | 0.096 | 0.1136 | No |
| 66 | Ipo7 | 7039 | 0.094 | 0.1127 | No |
| 67 | Stag1 | 7040 | 0.094 | 0.1156 | No |
| 68 | Trip13 | 7138 | 0.091 | 0.1135 | No |
| 69 | Phf5a | 7174 | 0.089 | 0.1144 | No |
| 70 | Stmn1 | 7256 | 0.086 | 0.1129 | No |
| 71 | Anp32e | 7278 | 0.085 | 0.1145 | No |
| 72 | Prim2 | 7401 | 0.081 | 0.1108 | No |
| 73 | Cbx5 | 7447 | 0.079 | 0.1109 | No |
| 74 | Exosc8 | 7512 | 0.077 | 0.1100 | No |
| 75 | Rad50 | 7562 | 0.075 | 0.1098 | No |
| 76 | Ak2 | 7692 | 0.071 | 0.1055 | No |
| 77 | Gins4 | 7727 | 0.070 | 0.1059 | No |
| 78 | Nup153 | 7887 | 0.066 | 0.0998 | No |
| 79 | Ranbp1 | 7962 | 0.063 | 0.0980 | No |
| 80 | Atad2 | 8036 | 0.060 | 0.0961 | No |
| 81 | Mcm6 | 8045 | 0.060 | 0.0976 | No |
| 82 | Zw10 | 8215 | 0.054 | 0.0906 | No |
| 83 | E2f8 | 8237 | 0.054 | 0.0912 | No |
| 84 | Pcna | 8283 | 0.052 | 0.0905 | No |
| 85 | Slbp | 8331 | 0.051 | 0.0897 | No |
| 86 | Wee1 | 8499 | 0.046 | 0.0826 | No |
| 87 | Tmpo | 8563 | 0.044 | 0.0807 | No |
| 88 | Pms2 | 8570 | 0.044 | 0.0818 | No |
| 89 | Birc5 | 8574 | 0.044 | 0.0830 | No |
| 90 | Gspt1 | 8670 | 0.041 | 0.0794 | No |
| 91 | Rfc2 | 8688 | 0.040 | 0.0797 | No |
| 92 | Psmc3ip | 8752 | 0.037 | 0.0777 | No |
| 93 | Prdx4 | 8890 | 0.033 | 0.0717 | No |
| 94 | Smc4 | 8930 | 0.032 | 0.0707 | No |
| 95 | Pold3 | 9153 | 0.025 | 0.0601 | No |
| 96 | Cdca8 | 9172 | 0.024 | 0.0599 | No |
| 97 | Mms22l | 9406 | 0.016 | 0.0485 | No |
| 98 | Psip1 | 9474 | 0.014 | 0.0455 | No |
| 99 | Tfrc | 9502 | 0.013 | 0.0446 | No |
| 100 | Brca1 | 9584 | 0.011 | 0.0407 | No |
| 101 | Racgap1 | 9730 | 0.006 | 0.0335 | No |
| 102 | Mybl2 | 9776 | 0.004 | 0.0313 | No |
| 103 | Plk1 | 9781 | 0.004 | 0.0313 | No |
| 104 | Cdkn1a | 9815 | 0.003 | 0.0297 | No |
| 105 | Gins1 | 10214 | -0.000 | 0.0093 | No |
| 106 | Tbrg4 | 10231 | -0.001 | 0.0085 | No |
| 107 | Mad2l1 | 10249 | -0.001 | 0.0077 | No |
| 108 | Mre11a | 10250 | -0.001 | 0.0078 | No |
| 109 | Nme1 | 10262 | -0.002 | 0.0072 | No |
| 110 | Rpa3 | 10364 | -0.005 | 0.0022 | No |
| 111 | Ube2t | 10371 | -0.005 | 0.0021 | No |
| 112 | Rrm2 | 10372 | -0.005 | 0.0023 | No |
| 113 | Hmgb3 | 10396 | -0.006 | 0.0013 | No |
| 114 | Orc2 | 10461 | -0.007 | -0.0018 | No |
| 115 | H2ax | 10523 | -0.010 | -0.0046 | No |
| 116 | Syncrip | 10531 | -0.010 | -0.0046 | No |
| 117 | Ddx39a | 10567 | -0.011 | -0.0061 | No |
| 118 | Pan2 | 10956 | -0.024 | -0.0252 | No |
| 119 | Srsf2 | 11004 | -0.026 | -0.0268 | No |
| 120 | Cdca3 | 11136 | -0.030 | -0.0325 | No |
| 121 | Rbbp7 | 11383 | -0.038 | -0.0439 | No |
| 122 | Ccnb2 | 11619 | -0.044 | -0.0546 | No |
| 123 | Cdk4 | 11737 | -0.048 | -0.0590 | No |
| 124 | Nbn | 11752 | -0.049 | -0.0583 | No |
| 125 | Nup107 | 11775 | -0.050 | -0.0578 | No |
| 126 | Ccp110 | 11808 | -0.051 | -0.0579 | No |
| 127 | Chek2 | 11902 | -0.054 | -0.0610 | No |
| 128 | Lig1 | 11920 | -0.055 | -0.0602 | No |
| 129 | Timeless | 12053 | -0.060 | -0.0650 | No |
| 130 | Ncapd2 | 12070 | -0.061 | -0.0640 | No |
| 131 | Pds5b | 12090 | -0.062 | -0.0630 | No |
| 132 | Msh2 | 12242 | -0.068 | -0.0687 | No |
| 133 | Mcm3 | 12368 | -0.072 | -0.0728 | No |
| 134 | Xrcc6 | 12432 | -0.074 | -0.0738 | No |
| 135 | Cenpm | 12508 | -0.077 | -0.0752 | No |
| 136 | Hmgb2 | 12622 | -0.081 | -0.0785 | No |
| 137 | Tk1 | 12730 | -0.085 | -0.0814 | No |
| 138 | Rpa1 | 12769 | -0.086 | -0.0807 | No |
| 139 | Rnaseh2a | 12861 | -0.089 | -0.0826 | No |
| 140 | H2az1 | 12872 | -0.089 | -0.0803 | No |
| 141 | Smc1a | 13005 | -0.095 | -0.0841 | No |
| 142 | Paics | 13018 | -0.096 | -0.0818 | No |
| 143 | Ctcf | 13087 | -0.099 | -0.0822 | No |
| 144 | Tubg1 | 13143 | -0.101 | -0.0819 | No |
| 145 | Mthfd2 | 13213 | -0.104 | -0.0822 | No |
| 146 | Ubr7 | 13452 | -0.114 | -0.0909 | No |
| 147 | Mcm5 | 13546 | -0.117 | -0.0920 | No |
| 148 | Brms1l | 13785 | -0.127 | -0.1002 | No |
| 149 | Mcm2 | 14092 | -0.140 | -0.1115 | No |
| 150 | Cdc20 | 14176 | -0.144 | -0.1113 | No |
| 151 | Ssrp1 | 14311 | -0.150 | -0.1136 | No |
| 152 | Mcm7 | 14398 | -0.153 | -0.1132 | No |
| 153 | Snrpb | 14411 | -0.153 | -0.1091 | No |
| 154 | Nop56 | 14490 | -0.157 | -0.1083 | No |
| 155 | Dek | 14508 | -0.157 | -0.1043 | No |
| 156 | Trp53 | 14516 | -0.158 | -0.0997 | No |
| 157 | Rfc1 | 14537 | -0.159 | -0.0959 | No |
| 158 | Chek1 | 14569 | -0.160 | -0.0925 | No |
| 159 | Lyar | 14576 | -0.160 | -0.0879 | No |
| 160 | Nap1l1 | 14616 | -0.162 | -0.0848 | No |
| 161 | Smc3 | 14752 | -0.169 | -0.0865 | No |
| 162 | Smc6 | 14883 | -0.175 | -0.0878 | No |
| 163 | Ung | 14959 | -0.179 | -0.0861 | No |
| 164 | Dclre1b | 14988 | -0.181 | -0.0819 | No |
| 165 | Luc7l3 | 15061 | -0.184 | -0.0799 | No |
| 166 | Gins3 | 15145 | -0.187 | -0.0784 | No |
| 167 | Pa2g4 | 15189 | -0.189 | -0.0747 | No |
| 168 | Eed | 15239 | -0.190 | -0.0713 | No |
| 169 | Tcf19 | 15292 | -0.194 | -0.0680 | No |
| 170 | Spc24 | 15441 | -0.200 | -0.0694 | No |
| 171 | Rpa2 | 15651 | -0.211 | -0.0735 | No |
| 172 | Eif2s1 | 15809 | -0.218 | -0.0748 | No |
| 173 | Hnrnpd | 15844 | -0.220 | -0.0698 | No |
| 174 | Usp1 | 15854 | -0.220 | -0.0634 | No |
| 175 | Cdc25a | 15897 | -0.222 | -0.0587 | No |
| 176 | Ppm1d | 15983 | -0.227 | -0.0561 | No |
| 177 | Nudt21 | 16057 | -0.231 | -0.0526 | No |
| 178 | Srsf1 | 16122 | -0.235 | -0.0487 | No |
| 179 | Jpt1 | 16366 | -0.245 | -0.0535 | No |
| 180 | Suv39h1 | 16387 | -0.246 | -0.0469 | No |
| 181 | Dctpp1 | 16497 | -0.252 | -0.0447 | No |
| 182 | Rfc3 | 16682 | -0.263 | -0.0460 | No |
| 183 | Ppp1r8 | 17050 | -0.284 | -0.0559 | No |
| 184 | Ran | 17156 | -0.290 | -0.0524 | No |
| 185 | Rad51ap1 | 17163 | -0.291 | -0.0437 | No |
| 186 | Nolc1 | 17424 | -0.309 | -0.0474 | No |
| 187 | Asf1a | 17738 | -0.330 | -0.0532 | No |
| 188 | Tubb5 | 17746 | -0.331 | -0.0433 | No |
| 189 | Hmga1b | 17777 | -0.333 | -0.0346 | No |
| 190 | Lsm8 | 18060 | -0.359 | -0.0379 | No |
| 191 | Orc6 | 18136 | -0.367 | -0.0304 | No |
| 192 | Pole4 | 18515 | -0.415 | -0.0369 | No |
| 193 | Myc | 18782 | -0.448 | -0.0366 | No |
| 194 | Cks1b | 19063 | -0.495 | -0.0356 | No |
| 195 | Rad51c | 19164 | -0.514 | -0.0249 | No |
| 196 | Prps1 | 19414 | -0.583 | -0.0196 | No |
| 197 | Rad1 | 19452 | -0.599 | -0.0030 | No |
| 198 | Dut | 19495 | -0.622 | 0.0141 | No |

