| Dataset | CMP.CMP_Pheno.cls#Group6_versus_Group8.CMP_Pheno.cls#Group6_versus_Group8_repos |
| Phenotype | CMP_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_COMPLEMENT |
| Enrichment Score (ES) | -0.325201 |
| Normalized Enrichment Score (NES) | -1.4291968 |
| Nominal p-value | 0.014373717 |
| FDR q-value | 0.25092652 |
| FWER p-Value | 0.478 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Phex | 189 | 0.728 | 0.0119 | No |
| 2 | Sh2b3 | 395 | 0.593 | 0.0189 | No |
| 3 | Kynu | 614 | 0.556 | 0.0242 | No |
| 4 | Cdk5r1 | 1304 | 0.423 | 0.0016 | No |
| 5 | C1qc | 1309 | 0.423 | 0.0138 | No |
| 6 | Irf7 | 1786 | 0.383 | 0.0009 | No |
| 7 | Dyrk2 | 1821 | 0.379 | 0.0103 | No |
| 8 | Sirt6 | 1978 | 0.357 | 0.0129 | No |
| 9 | Tfpi2 | 2097 | 0.343 | 0.0170 | No |
| 10 | Cpm | 2493 | 0.304 | 0.0059 | No |
| 11 | Pik3ca | 2583 | 0.297 | 0.0101 | No |
| 12 | Gnb4 | 2916 | 0.275 | 0.0013 | No |
| 13 | Zfpm2 | 2996 | 0.270 | 0.0052 | No |
| 14 | Rasgrp1 | 3038 | 0.268 | 0.0110 | No |
| 15 | Fyn | 3234 | 0.262 | 0.0088 | No |
| 16 | Vcpip1 | 3265 | 0.260 | 0.0150 | No |
| 17 | Fn1 | 3355 | 0.254 | 0.0179 | No |
| 18 | F8 | 3739 | 0.238 | 0.0054 | No |
| 19 | Fcnb | 3818 | 0.234 | 0.0083 | No |
| 20 | Ctss | 3891 | 0.233 | 0.0115 | No |
| 21 | Lcp2 | 3967 | 0.228 | 0.0145 | No |
| 22 | Scg3 | 4045 | 0.225 | 0.0172 | No |
| 23 | Src | 4143 | 0.223 | 0.0188 | No |
| 24 | Mmp15 | 4469 | 0.205 | 0.0083 | No |
| 25 | Clu | 4601 | 0.197 | 0.0074 | No |
| 26 | Irf2 | 4863 | 0.185 | -0.0005 | No |
| 27 | Lamp2 | 5003 | 0.178 | -0.0023 | No |
| 28 | Pclo | 5186 | 0.169 | -0.0066 | No |
| 29 | Dgkg | 5196 | 0.168 | -0.0021 | No |
| 30 | Kcnip3 | 5254 | 0.166 | -0.0001 | No |
| 31 | Rbsn | 5285 | 0.164 | 0.0032 | No |
| 32 | Plscr1 | 5789 | 0.142 | -0.0182 | No |
| 33 | Ppp4c | 5801 | 0.142 | -0.0146 | No |
| 34 | Usp8 | 5915 | 0.137 | -0.0163 | No |
| 35 | Casp4 | 6283 | 0.122 | -0.0314 | No |
| 36 | Usp14 | 6501 | 0.114 | -0.0391 | No |
| 37 | Plg | 6595 | 0.111 | -0.0406 | No |
| 38 | Usp15 | 6672 | 0.107 | -0.0413 | No |
| 39 | Dusp5 | 6722 | 0.106 | -0.0407 | No |
| 40 | Pik3cg | 6883 | 0.099 | -0.0459 | No |
| 41 | Plek | 6957 | 0.097 | -0.0468 | No |
| 42 | C9 | 6994 | 0.095 | -0.0458 | No |
| 43 | Olr1 | 7018 | 0.095 | -0.0442 | No |
| 44 | Lyn | 7160 | 0.090 | -0.0487 | No |
| 45 | Kif2a | 7289 | 0.085 | -0.0528 | No |
| 46 | Grb2 | 7375 | 0.082 | -0.0547 | No |
| 47 | Rabif | 7608 | 0.074 | -0.0643 | No |
| 48 | Plaur | 7709 | 0.071 | -0.0673 | No |
| 49 | Pfn1 | 7710 | 0.071 | -0.0653 | No |
| 50 | Ctso | 7718 | 0.070 | -0.0635 | No |
| 51 | Cd36 | 7748 | 0.070 | -0.0630 | No |
| 52 | Zeb1 | 7791 | 0.069 | -0.0631 | No |
| 53 | Gngt2 | 7804 | 0.068 | -0.0617 | No |
| 54 | Ctsc | 7956 | 0.063 | -0.0675 | No |
| 55 | Atox1 | 8014 | 0.061 | -0.0686 | No |
| 56 | Cebpb | 8144 | 0.057 | -0.0735 | No |
| 57 | Dock10 | 8330 | 0.051 | -0.0814 | No |
| 58 | Dusp6 | 8430 | 0.048 | -0.0850 | No |
| 59 | Spock2 | 8544 | 0.045 | -0.0895 | No |
| 60 | Gpd2 | 8906 | 0.033 | -0.1069 | No |
| 61 | Lgals3 | 8934 | 0.032 | -0.1074 | No |
| 62 | Actn2 | 9108 | 0.026 | -0.1154 | No |
| 63 | Gng2 | 9321 | 0.018 | -0.1257 | No |
| 64 | Csrp1 | 9469 | 0.014 | -0.1328 | No |
| 65 | Dgkh | 9741 | 0.005 | -0.1464 | No |
| 66 | C1qa | 9754 | 0.005 | -0.1469 | No |
| 67 | Adam9 | 9755 | 0.005 | -0.1468 | No |
| 68 | Prdm4 | 9814 | 0.003 | -0.1496 | No |
| 69 | Prkcd | 9877 | 0.001 | -0.1528 | No |
| 70 | Ang | 9978 | 0.000 | -0.1579 | No |
| 71 | Fdx1 | 10296 | -0.003 | -0.1740 | No |
| 72 | Pim1 | 10313 | -0.003 | -0.1747 | No |
| 73 | Hspa1a | 10322 | -0.004 | -0.1750 | No |
| 74 | Casp1 | 10436 | -0.007 | -0.1805 | No |
| 75 | Pla2g4a | 10512 | -0.009 | -0.1841 | No |
| 76 | Raf1 | 10587 | -0.012 | -0.1875 | No |
| 77 | F3 | 10714 | -0.016 | -0.1935 | No |
| 78 | Mmp14 | 10754 | -0.017 | -0.1950 | No |
| 79 | Gnai3 | 10840 | -0.020 | -0.1987 | No |
| 80 | Dock9 | 11015 | -0.026 | -0.2068 | No |
| 81 | Lta4h | 11039 | -0.027 | -0.2072 | No |
| 82 | Ehd1 | 11238 | -0.034 | -0.2163 | No |
| 83 | Il6 | 11312 | -0.036 | -0.2189 | No |
| 84 | Prep | 11366 | -0.037 | -0.2205 | No |
| 85 | Prcp | 11469 | -0.040 | -0.2245 | No |
| 86 | Notch4 | 11488 | -0.041 | -0.2242 | No |
| 87 | Akap10 | 11599 | -0.044 | -0.2286 | No |
| 88 | Col4a2 | 11806 | -0.051 | -0.2376 | No |
| 89 | Casp7 | 11998 | -0.059 | -0.2456 | No |
| 90 | Kcnip2 | 12017 | -0.059 | -0.2448 | No |
| 91 | Cblb | 12088 | -0.062 | -0.2465 | No |
| 92 | Lap3 | 12280 | -0.069 | -0.2542 | No |
| 93 | Casp9 | 12290 | -0.069 | -0.2526 | No |
| 94 | Fcer1g | 12414 | -0.073 | -0.2567 | No |
| 95 | Cpq | 12476 | -0.075 | -0.2576 | No |
| 96 | Brpf3 | 12535 | -0.078 | -0.2583 | No |
| 97 | Gp9 | 12697 | -0.084 | -0.2640 | No |
| 98 | F7 | 13161 | -0.102 | -0.2846 | No |
| 99 | Jak2 | 13483 | -0.115 | -0.2976 | No |
| 100 | Gp1ba | 13509 | -0.116 | -0.2955 | No |
| 101 | Gca | 13554 | -0.117 | -0.2943 | No |
| 102 | Gnai2 | 13599 | -0.119 | -0.2930 | No |
| 103 | Cd46 | 13674 | -0.122 | -0.2932 | No |
| 104 | Hnf4a | 13834 | -0.129 | -0.2975 | No |
| 105 | Lipa | 13861 | -0.130 | -0.2949 | No |
| 106 | Usp16 | 13883 | -0.131 | -0.2921 | No |
| 107 | Dock4 | 14082 | -0.140 | -0.2981 | No |
| 108 | Xpnpep1 | 14465 | -0.156 | -0.3130 | No |
| 109 | F10 | 14480 | -0.156 | -0.3091 | No |
| 110 | Serpinb2 | 14719 | -0.167 | -0.3163 | No |
| 111 | Cfb | 14801 | -0.171 | -0.3154 | No |
| 112 | Psmb9 | 14867 | -0.174 | -0.3135 | No |
| 113 | Car2 | 14937 | -0.178 | -0.3118 | No |
| 114 | Msrb1 | 14955 | -0.179 | -0.3074 | No |
| 115 | Ctsh | 15265 | -0.192 | -0.3175 | No |
| 116 | Dpp4 | 15417 | -0.199 | -0.3193 | Yes |
| 117 | Casp3 | 15433 | -0.200 | -0.3142 | Yes |
| 118 | Calm3 | 15470 | -0.202 | -0.3100 | Yes |
| 119 | Rce1 | 15473 | -0.202 | -0.3042 | Yes |
| 120 | Ctsd | 15584 | -0.208 | -0.3037 | Yes |
| 121 | Lgmn | 15692 | -0.212 | -0.3028 | Yes |
| 122 | Ppp2cb | 15698 | -0.213 | -0.2968 | Yes |
| 123 | Prss36 | 15777 | -0.217 | -0.2944 | Yes |
| 124 | Pdgfb | 15802 | -0.218 | -0.2892 | Yes |
| 125 | Stx4a | 15891 | -0.222 | -0.2871 | Yes |
| 126 | Lrp1 | 16021 | -0.230 | -0.2869 | Yes |
| 127 | Ctsl | 16237 | -0.242 | -0.2908 | Yes |
| 128 | Cdh13 | 16424 | -0.248 | -0.2929 | Yes |
| 129 | Cp | 16462 | -0.250 | -0.2874 | Yes |
| 130 | Anxa5 | 16690 | -0.263 | -0.2912 | Yes |
| 131 | Hspa5 | 16790 | -0.270 | -0.2883 | Yes |
| 132 | Rhog | 16800 | -0.271 | -0.2807 | Yes |
| 133 | Cr2 | 16925 | -0.279 | -0.2788 | Yes |
| 134 | Psen1 | 16942 | -0.280 | -0.2714 | Yes |
| 135 | Mmp8 | 16985 | -0.283 | -0.2652 | Yes |
| 136 | Apoc1 | 17069 | -0.285 | -0.2610 | Yes |
| 137 | L3mbtl4 | 17403 | -0.307 | -0.2689 | Yes |
| 138 | Pcsk9 | 17633 | -0.326 | -0.2710 | Yes |
| 139 | Gzmk | 17653 | -0.328 | -0.2622 | Yes |
| 140 | Rnf4 | 17779 | -0.333 | -0.2588 | Yes |
| 141 | Lck | 17804 | -0.336 | -0.2501 | Yes |
| 142 | Ltf | 18039 | -0.357 | -0.2515 | Yes |
| 143 | Itgam | 18087 | -0.362 | -0.2432 | Yes |
| 144 | C2 | 18294 | -0.385 | -0.2423 | Yes |
| 145 | Ctsb | 18359 | -0.394 | -0.2340 | Yes |
| 146 | Tnfaip3 | 18413 | -0.401 | -0.2248 | Yes |
| 147 | Serpinc1 | 18456 | -0.406 | -0.2150 | Yes |
| 148 | S100a9 | 18486 | -0.411 | -0.2043 | Yes |
| 149 | Klkb1 | 18565 | -0.422 | -0.1958 | Yes |
| 150 | Gnb2 | 18593 | -0.426 | -0.1846 | Yes |
| 151 | Pik3r5 | 18622 | -0.430 | -0.1733 | Yes |
| 152 | Calm1 | 18818 | -0.453 | -0.1699 | Yes |
| 153 | Ccl5 | 18891 | -0.465 | -0.1598 | Yes |
| 154 | Gmfb | 18922 | -0.471 | -0.1475 | Yes |
| 155 | C3 | 19078 | -0.497 | -0.1407 | Yes |
| 156 | Maff | 19156 | -0.513 | -0.1295 | Yes |
| 157 | Was | 19188 | -0.520 | -0.1157 | Yes |
| 158 | Irf1 | 19361 | -0.565 | -0.1078 | Yes |
| 159 | Me1 | 19430 | -0.589 | -0.0939 | Yes |
| 160 | S100a13 | 19571 | -0.659 | -0.0816 | Yes |
| 161 | Gata3 | 19582 | -0.665 | -0.0624 | Yes |
| 162 | Pdp1 | 19589 | -0.674 | -0.0429 | Yes |
| 163 | F5 | 19717 | -0.827 | -0.0249 | Yes |
| 164 | Timp2 | 19751 | -0.936 | 0.0010 | Yes |

