| Dataset | CMP.CMP_Pheno.cls#Group3_versus_Group4.CMP_Pheno.cls#Group3_versus_Group4_repos |
| Phenotype | CMP_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | 0.23531447 |
| Normalized Enrichment Score (NES) | 0.92086446 |
| Nominal p-value | 0.55959594 |
| FDR q-value | 0.90387774 |
| FWER p-Value | 0.991 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cd80 | 136 | 0.816 | 0.0203 | Yes |
| 2 | Tnf | 293 | 0.678 | 0.0350 | Yes |
| 3 | Itgb2 | 473 | 0.608 | 0.0461 | Yes |
| 4 | Cd247 | 487 | 0.602 | 0.0656 | Yes |
| 5 | Ccl5 | 628 | 0.566 | 0.0773 | Yes |
| 6 | Hdac9 | 677 | 0.551 | 0.0933 | Yes |
| 7 | H2-Oa | 822 | 0.518 | 0.1032 | Yes |
| 8 | Il12a | 902 | 0.505 | 0.1160 | Yes |
| 9 | Il18 | 903 | 0.505 | 0.1329 | Yes |
| 10 | Ltb | 960 | 0.492 | 0.1465 | Yes |
| 11 | Crtam | 1335 | 0.441 | 0.1421 | Yes |
| 12 | Bcat1 | 1539 | 0.417 | 0.1457 | Yes |
| 13 | Il7 | 1583 | 0.414 | 0.1573 | Yes |
| 14 | Fas | 2043 | 0.365 | 0.1461 | Yes |
| 15 | Akt1 | 2064 | 0.363 | 0.1572 | Yes |
| 16 | Csf1 | 2205 | 0.351 | 0.1618 | Yes |
| 17 | Ccr5 | 2231 | 0.348 | 0.1721 | Yes |
| 18 | Mmp9 | 2486 | 0.327 | 0.1701 | Yes |
| 19 | C2 | 2535 | 0.325 | 0.1785 | Yes |
| 20 | Cd96 | 2676 | 0.314 | 0.1818 | Yes |
| 21 | Eif3j1 | 2691 | 0.312 | 0.1915 | Yes |
| 22 | Csk | 3193 | 0.272 | 0.1750 | Yes |
| 23 | Thy1 | 3246 | 0.268 | 0.1813 | Yes |
| 24 | Il12rb1 | 3294 | 0.265 | 0.1878 | Yes |
| 25 | Nme1 | 3350 | 0.262 | 0.1937 | Yes |
| 26 | Mrpl3 | 3425 | 0.258 | 0.1986 | Yes |
| 27 | Tlr1 | 3451 | 0.256 | 0.2058 | Yes |
| 28 | Traf2 | 3497 | 0.254 | 0.2120 | Yes |
| 29 | F2r | 3581 | 0.248 | 0.2161 | Yes |
| 30 | Egfr | 3690 | 0.242 | 0.2187 | Yes |
| 31 | Il2rg | 3833 | 0.237 | 0.2193 | Yes |
| 32 | Cd79a | 3992 | 0.227 | 0.2188 | Yes |
| 33 | Gcnt1 | 4092 | 0.221 | 0.2212 | Yes |
| 34 | Ifngr2 | 4153 | 0.219 | 0.2254 | Yes |
| 35 | Hif1a | 4202 | 0.216 | 0.2302 | Yes |
| 36 | H2-Ob | 4242 | 0.213 | 0.2353 | Yes |
| 37 | Il27ra | 4402 | 0.207 | 0.2341 | No |
| 38 | Itk | 4660 | 0.193 | 0.2275 | No |
| 39 | Ache | 4883 | 0.181 | 0.2222 | No |
| 40 | Ccnd2 | 5566 | 0.152 | 0.1925 | No |
| 41 | Abce1 | 5645 | 0.148 | 0.1935 | No |
| 42 | Ets1 | 5742 | 0.145 | 0.1934 | No |
| 43 | Was | 5818 | 0.141 | 0.1943 | No |
| 44 | Icam1 | 6547 | 0.116 | 0.1611 | No |
| 45 | Capg | 6568 | 0.115 | 0.1639 | No |
| 46 | Galnt1 | 6632 | 0.113 | 0.1644 | No |
| 47 | Itgal | 6679 | 0.111 | 0.1658 | No |
| 48 | Apbb1 | 6913 | 0.102 | 0.1573 | No |
| 49 | H2-Aa | 7338 | 0.087 | 0.1386 | No |
| 50 | Cd4 | 7518 | 0.081 | 0.1322 | No |
| 51 | Abi1 | 7604 | 0.078 | 0.1305 | No |
| 52 | Tgfb1 | 7717 | 0.074 | 0.1272 | No |
| 53 | Irf8 | 7721 | 0.073 | 0.1295 | No |
| 54 | Ripk2 | 7869 | 0.069 | 0.1244 | No |
| 55 | Flna | 7926 | 0.067 | 0.1238 | No |
| 56 | Cd1d2 | 8276 | 0.056 | 0.1078 | No |
| 57 | Elane | 8426 | 0.051 | 0.1019 | No |
| 58 | Bcl3 | 8500 | 0.048 | 0.0998 | No |
| 59 | Fgr | 8510 | 0.047 | 0.1009 | No |
| 60 | Degs1 | 8555 | 0.046 | 0.1002 | No |
| 61 | Map3k7 | 8684 | 0.042 | 0.0951 | No |
| 62 | Ly75 | 8745 | 0.040 | 0.0933 | No |
| 63 | Cd74 | 8935 | 0.033 | 0.0848 | No |
| 64 | Mtif2 | 8947 | 0.032 | 0.0853 | No |
| 65 | Wars1 | 8961 | 0.032 | 0.0857 | No |
| 66 | Ube2n | 9029 | 0.030 | 0.0833 | No |
| 67 | Tpd52 | 9208 | 0.024 | 0.0750 | No |
| 68 | Fcgr2b | 9240 | 0.023 | 0.0742 | No |
| 69 | Rpl9 | 9374 | 0.019 | 0.0680 | No |
| 70 | Glmn | 9472 | 0.016 | 0.0636 | No |
| 71 | Jak2 | 9601 | 0.011 | 0.0575 | No |
| 72 | Il2ra | 9963 | 0.000 | 0.0391 | No |
| 73 | St8sia4 | 10080 | -0.000 | 0.0332 | No |
| 74 | Rps3a1 | 10154 | -0.002 | 0.0295 | No |
| 75 | Il11 | 10192 | -0.004 | 0.0278 | No |
| 76 | Ccr1 | 10212 | -0.004 | 0.0269 | No |
| 77 | H2-DMa | 10231 | -0.005 | 0.0262 | No |
| 78 | Map4k1 | 10272 | -0.006 | 0.0243 | No |
| 79 | Cd47 | 10504 | -0.013 | 0.0130 | No |
| 80 | Zap70 | 10574 | -0.016 | 0.0100 | No |
| 81 | Ptprc | 11152 | -0.034 | -0.0183 | No |
| 82 | Ccr2 | 11181 | -0.035 | -0.0185 | No |
| 83 | B2m | 11295 | -0.038 | -0.0230 | No |
| 84 | Srgn | 11509 | -0.044 | -0.0324 | No |
| 85 | Prkcb | 11660 | -0.049 | -0.0384 | No |
| 86 | Eif4g3 | 11746 | -0.052 | -0.0410 | No |
| 87 | Ncf4 | 11912 | -0.058 | -0.0475 | No |
| 88 | Bcl10 | 11927 | -0.058 | -0.0462 | No |
| 89 | Tap1 | 12050 | -0.062 | -0.0504 | No |
| 90 | Lck | 12097 | -0.063 | -0.0506 | No |
| 91 | H2-DMb2 | 12138 | -0.065 | -0.0505 | No |
| 92 | Il6 | 12296 | -0.070 | -0.0562 | No |
| 93 | Lyn | 12542 | -0.076 | -0.0661 | No |
| 94 | Tapbp | 12573 | -0.077 | -0.0651 | No |
| 95 | Psmb10 | 12592 | -0.077 | -0.0634 | No |
| 96 | Ikbkb | 12727 | -0.081 | -0.0676 | No |
| 97 | Socs5 | 12918 | -0.088 | -0.0743 | No |
| 98 | Eif3a | 13098 | -0.094 | -0.0803 | No |
| 99 | Ifngr1 | 13182 | -0.098 | -0.0813 | No |
| 100 | Tlr2 | 13274 | -0.101 | -0.0825 | No |
| 101 | Tlr3 | 13320 | -0.103 | -0.0814 | No |
| 102 | Cfp | 13332 | -0.103 | -0.0785 | No |
| 103 | Tgfb2 | 13460 | -0.108 | -0.0814 | No |
| 104 | Nlrp3 | 13482 | -0.108 | -0.0789 | No |
| 105 | Stat4 | 13709 | -0.117 | -0.0865 | No |
| 106 | Stab1 | 13745 | -0.119 | -0.0843 | No |
| 107 | Irf4 | 13748 | -0.119 | -0.0804 | No |
| 108 | Npm1 | 13809 | -0.121 | -0.0794 | No |
| 109 | Hcls1 | 14120 | -0.133 | -0.0908 | No |
| 110 | Icosl | 14486 | -0.147 | -0.1045 | No |
| 111 | Il10 | 14498 | -0.148 | -0.1001 | No |
| 112 | Il18rap | 14795 | -0.161 | -0.1098 | No |
| 113 | Eif3d | 14804 | -0.161 | -0.1049 | No |
| 114 | Il16 | 14987 | -0.170 | -0.1085 | No |
| 115 | Igsf6 | 14991 | -0.170 | -0.1029 | No |
| 116 | Ptpn6 | 15003 | -0.171 | -0.0978 | No |
| 117 | Eif5a | 15022 | -0.171 | -0.0930 | No |
| 118 | Il1b | 15050 | -0.172 | -0.0886 | No |
| 119 | Tlr6 | 15164 | -0.174 | -0.0886 | No |
| 120 | Il15 | 15203 | -0.175 | -0.0847 | No |
| 121 | Ube2d1 | 15257 | -0.177 | -0.0815 | No |
| 122 | Acvr2a | 15350 | -0.181 | -0.0801 | No |
| 123 | Inhba | 15391 | -0.183 | -0.0760 | No |
| 124 | Il2 | 15654 | -0.195 | -0.0829 | No |
| 125 | Trat1 | 15679 | -0.196 | -0.0775 | No |
| 126 | Nck1 | 15777 | -0.202 | -0.0758 | No |
| 127 | Spi1 | 15794 | -0.203 | -0.0698 | No |
| 128 | Ifnar2 | 15853 | -0.206 | -0.0659 | No |
| 129 | Rps9 | 16022 | -0.214 | -0.0673 | No |
| 130 | Ctss | 16067 | -0.216 | -0.0623 | No |
| 131 | Brca1 | 16123 | -0.220 | -0.0578 | No |
| 132 | Ly86 | 16272 | -0.227 | -0.0577 | No |
| 133 | Rpl3l | 16352 | -0.232 | -0.0540 | No |
| 134 | Cdkn2a | 16365 | -0.232 | -0.0469 | No |
| 135 | Il4 | 16383 | -0.233 | -0.0400 | No |
| 136 | Cd86 | 16763 | -0.257 | -0.0507 | No |
| 137 | Stat1 | 16808 | -0.260 | -0.0443 | No |
| 138 | Tap2 | 17222 | -0.288 | -0.0557 | No |
| 139 | Elf4 | 17388 | -0.298 | -0.0542 | No |
| 140 | Gpr65 | 17401 | -0.298 | -0.0449 | No |
| 141 | Cxcl9 | 17426 | -0.300 | -0.0360 | No |
| 142 | Il4ra | 17537 | -0.308 | -0.0314 | No |
| 143 | Lcp2 | 17611 | -0.314 | -0.0246 | No |
| 144 | Socs1 | 17976 | -0.345 | -0.0317 | No |
| 145 | Lif | 18445 | -0.392 | -0.0424 | No |
| 146 | Ccnd3 | 18696 | -0.424 | -0.0410 | No |
| 147 | Cd28 | 18731 | -0.428 | -0.0285 | No |
| 148 | Pf4 | 18983 | -0.471 | -0.0256 | No |
| 149 | Irf7 | 19441 | -0.587 | -0.0293 | No |
| 150 | Dyrk3 | 19469 | -0.599 | -0.0106 | No |
| 151 | Prkcg | 19690 | -0.778 | 0.0041 | No |

