| Dataset | CMP.CMP_Pheno.cls#Group2_versus_Group4.CMP_Pheno.cls#Group2_versus_Group4_repos |
| Phenotype | CMP_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_P53_PATHWAY |
| Enrichment Score (ES) | -0.22672054 |
| Normalized Enrichment Score (NES) | -0.94091076 |
| Nominal p-value | 0.53817505 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.993 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Zfp365 | 10 | 1.131 | 0.0231 | No |
| 2 | Ccp110 | 73 | 0.916 | 0.0390 | No |
| 3 | Slc35d1 | 528 | 0.619 | 0.0287 | No |
| 4 | Stom | 715 | 0.569 | 0.0311 | No |
| 5 | App | 824 | 0.548 | 0.0370 | No |
| 6 | S100a4 | 971 | 0.524 | 0.0404 | No |
| 7 | Plk3 | 1241 | 0.485 | 0.0368 | No |
| 8 | Ada | 1272 | 0.480 | 0.0453 | No |
| 9 | Epha2 | 1346 | 0.470 | 0.0513 | No |
| 10 | Tchh | 1355 | 0.470 | 0.0607 | No |
| 11 | Ak1 | 1361 | 0.469 | 0.0702 | No |
| 12 | Dcxr | 1532 | 0.452 | 0.0710 | No |
| 13 | Cdkn2aip | 1601 | 0.444 | 0.0768 | No |
| 14 | Fas | 1619 | 0.442 | 0.0851 | No |
| 15 | Pmm1 | 1976 | 0.403 | 0.0753 | No |
| 16 | Aen | 1985 | 0.402 | 0.0833 | No |
| 17 | Tob1 | 2001 | 0.401 | 0.0909 | No |
| 18 | Cdkn1a | 2287 | 0.374 | 0.0841 | No |
| 19 | Hspa4l | 2310 | 0.372 | 0.0907 | No |
| 20 | H1f2 | 2313 | 0.371 | 0.0984 | No |
| 21 | Ercc5 | 2417 | 0.363 | 0.1007 | No |
| 22 | Nudt15 | 2437 | 0.361 | 0.1072 | No |
| 23 | Tspyl2 | 2558 | 0.354 | 0.1085 | No |
| 24 | Bax | 2793 | 0.338 | 0.1036 | No |
| 25 | Hexim1 | 2824 | 0.336 | 0.1091 | No |
| 26 | Hmox1 | 2987 | 0.324 | 0.1075 | No |
| 27 | F2r | 3279 | 0.304 | 0.0990 | No |
| 28 | Sfn | 3280 | 0.304 | 0.1054 | No |
| 29 | Baiap2 | 3335 | 0.300 | 0.1089 | No |
| 30 | Csrnp2 | 3600 | 0.285 | 0.1013 | No |
| 31 | Fos | 3727 | 0.278 | 0.1007 | No |
| 32 | Tax1bp3 | 3800 | 0.274 | 0.1027 | No |
| 33 | Ddb2 | 3858 | 0.270 | 0.1054 | No |
| 34 | Upp1 | 3887 | 0.268 | 0.1096 | No |
| 35 | Foxo3 | 4042 | 0.258 | 0.1071 | No |
| 36 | Elp1 | 4056 | 0.257 | 0.1118 | No |
| 37 | Jag2 | 4266 | 0.242 | 0.1062 | No |
| 38 | Fam162a | 4474 | 0.230 | 0.1004 | No |
| 39 | Wwp1 | 4489 | 0.229 | 0.1045 | No |
| 40 | Polh | 4522 | 0.227 | 0.1076 | No |
| 41 | Pvt1 | 4552 | 0.226 | 0.1108 | No |
| 42 | Apaf1 | 4653 | 0.222 | 0.1103 | No |
| 43 | Rrp8 | 5181 | 0.192 | 0.0874 | No |
| 44 | Rhbdf2 | 5400 | 0.183 | 0.0801 | No |
| 45 | Plxnb2 | 5404 | 0.183 | 0.0837 | No |
| 46 | Pcna | 5427 | 0.182 | 0.0864 | No |
| 47 | Acvr1b | 5458 | 0.180 | 0.0886 | No |
| 48 | Prmt2 | 5484 | 0.179 | 0.0911 | No |
| 49 | Perp | 5595 | 0.173 | 0.0891 | No |
| 50 | Hint1 | 5701 | 0.168 | 0.0872 | No |
| 51 | Gadd45a | 6046 | 0.153 | 0.0728 | No |
| 52 | Rad51c | 6074 | 0.151 | 0.0746 | No |
| 53 | Fbxw7 | 6147 | 0.147 | 0.0740 | No |
| 54 | Cyfip2 | 6182 | 0.145 | 0.0752 | No |
| 55 | Ier5 | 6194 | 0.144 | 0.0777 | No |
| 56 | Nupr1 | 6389 | 0.136 | 0.0706 | No |
| 57 | Sp1 | 6554 | 0.129 | 0.0649 | No |
| 58 | Ctsd | 6557 | 0.129 | 0.0675 | No |
| 59 | Xpc | 6605 | 0.127 | 0.0678 | No |
| 60 | H2ac25 | 6730 | 0.120 | 0.0639 | No |
| 61 | Rab40c | 6786 | 0.118 | 0.0636 | No |
| 62 | H2aj | 6863 | 0.114 | 0.0621 | No |
| 63 | Traf4 | 7264 | 0.096 | 0.0436 | No |
| 64 | Procr | 7398 | 0.089 | 0.0387 | No |
| 65 | Ifi30 | 7411 | 0.088 | 0.0399 | No |
| 66 | Trib3 | 7443 | 0.087 | 0.0402 | No |
| 67 | Tgfa | 7496 | 0.085 | 0.0393 | No |
| 68 | Steap3 | 7713 | 0.075 | 0.0298 | No |
| 69 | Cd82 | 7737 | 0.074 | 0.0302 | No |
| 70 | Fdxr | 7795 | 0.071 | 0.0287 | No |
| 71 | Rpl36 | 7938 | 0.066 | 0.0229 | No |
| 72 | Zmat3 | 8056 | 0.061 | 0.0181 | No |
| 73 | Tap1 | 8190 | 0.053 | 0.0125 | No |
| 74 | Vdr | 8216 | 0.052 | 0.0123 | No |
| 75 | Atf3 | 8249 | 0.051 | 0.0117 | No |
| 76 | Rpl18 | 8314 | 0.048 | 0.0094 | No |
| 77 | Phlda3 | 8481 | 0.041 | 0.0018 | No |
| 78 | Slc3a2 | 8626 | 0.034 | -0.0048 | No |
| 79 | Mknk2 | 8723 | 0.031 | -0.0091 | No |
| 80 | Sdc1 | 8758 | 0.029 | -0.0102 | No |
| 81 | Ei24 | 8786 | 0.028 | -0.0110 | No |
| 82 | Dnttip2 | 8860 | 0.025 | -0.0142 | No |
| 83 | Ddit4 | 9280 | 0.008 | -0.0354 | No |
| 84 | Ip6k2 | 9282 | 0.008 | -0.0353 | No |
| 85 | Jun | 9351 | 0.005 | -0.0387 | No |
| 86 | Dgka | 9363 | 0.004 | -0.0392 | No |
| 87 | Mdm2 | 9578 | -0.001 | -0.0501 | No |
| 88 | Nol8 | 9843 | -0.012 | -0.0633 | No |
| 89 | Hras | 9902 | -0.014 | -0.0660 | No |
| 90 | Ralgds | 9923 | -0.016 | -0.0667 | No |
| 91 | S100a10 | 9950 | -0.017 | -0.0677 | No |
| 92 | Txnip | 10002 | -0.019 | -0.0699 | No |
| 93 | Tpd52l1 | 10065 | -0.022 | -0.0726 | No |
| 94 | Rrad | 10215 | -0.028 | -0.0796 | No |
| 95 | St14 | 10289 | -0.031 | -0.0827 | No |
| 96 | Cdh13 | 10424 | -0.037 | -0.0888 | No |
| 97 | Trp53 | 10559 | -0.043 | -0.0947 | No |
| 98 | Klf4 | 10686 | -0.047 | -0.1002 | No |
| 99 | Rap2b | 11037 | -0.063 | -0.1167 | No |
| 100 | Rad9a | 11072 | -0.064 | -0.1171 | No |
| 101 | Prkab1 | 11116 | -0.066 | -0.1180 | No |
| 102 | Mapkapk3 | 11201 | -0.067 | -0.1208 | No |
| 103 | Rps12 | 11293 | -0.071 | -0.1240 | No |
| 104 | Sat1 | 11437 | -0.077 | -0.1297 | No |
| 105 | Sesn1 | 11517 | -0.081 | -0.1321 | No |
| 106 | Kif13b | 11706 | -0.088 | -0.1398 | No |
| 107 | Triap1 | 11832 | -0.093 | -0.1442 | No |
| 108 | Rps27l | 11900 | -0.097 | -0.1456 | No |
| 109 | Zfp36l1 | 11922 | -0.098 | -0.1447 | No |
| 110 | Ptpn14 | 12195 | -0.110 | -0.1563 | No |
| 111 | Cdkn2a | 12328 | -0.116 | -0.1606 | No |
| 112 | Abcc5 | 12413 | -0.120 | -0.1624 | No |
| 113 | Tm7sf3 | 12458 | -0.122 | -0.1621 | No |
| 114 | Casp1 | 12718 | -0.133 | -0.1726 | No |
| 115 | Ctsf | 12838 | -0.139 | -0.1757 | No |
| 116 | Hbegf | 12911 | -0.142 | -0.1764 | No |
| 117 | Vamp8 | 13288 | -0.157 | -0.1924 | No |
| 118 | Ldhb | 13447 | -0.165 | -0.1970 | No |
| 119 | Ccnd2 | 13537 | -0.169 | -0.1980 | No |
| 120 | Alox8 | 13597 | -0.172 | -0.1974 | No |
| 121 | Slc19a2 | 13805 | -0.180 | -0.2043 | No |
| 122 | Rnf19b | 13806 | -0.180 | -0.2005 | No |
| 123 | Fgf13 | 13815 | -0.180 | -0.1972 | No |
| 124 | Sec61a1 | 13831 | -0.181 | -0.1942 | No |
| 125 | Sphk1 | 13851 | -0.182 | -0.1914 | No |
| 126 | Coq8a | 14008 | -0.189 | -0.1954 | No |
| 127 | Trp63 | 14126 | -0.194 | -0.1973 | No |
| 128 | Ndrg1 | 14300 | -0.203 | -0.2019 | No |
| 129 | Plk2 | 14320 | -0.204 | -0.1987 | No |
| 130 | Slc7a11 | 14390 | -0.206 | -0.1979 | No |
| 131 | Dram1 | 14646 | -0.219 | -0.2063 | No |
| 132 | Rchy1 | 14692 | -0.222 | -0.2040 | No |
| 133 | Rxra | 14850 | -0.230 | -0.2072 | No |
| 134 | Trafd1 | 15226 | -0.249 | -0.2212 | Yes |
| 135 | Tsc22d1 | 15262 | -0.250 | -0.2178 | Yes |
| 136 | Lif | 15384 | -0.256 | -0.2186 | Yes |
| 137 | Ppm1d | 15475 | -0.261 | -0.2178 | Yes |
| 138 | Bak1 | 15651 | -0.270 | -0.2211 | Yes |
| 139 | Vwa5a | 15674 | -0.271 | -0.2166 | Yes |
| 140 | Ccng1 | 15719 | -0.274 | -0.2131 | Yes |
| 141 | Abat | 15753 | -0.275 | -0.2091 | Yes |
| 142 | Tgfb1 | 15770 | -0.277 | -0.2041 | Yes |
| 143 | Ddit3 | 15804 | -0.279 | -0.2000 | Yes |
| 144 | Tnfsf9 | 15814 | -0.279 | -0.1947 | Yes |
| 145 | Osgin1 | 15924 | -0.285 | -0.1943 | Yes |
| 146 | Pdgfa | 16003 | -0.290 | -0.1922 | Yes |
| 147 | Blcap | 16052 | -0.293 | -0.1886 | Yes |
| 148 | Ephx1 | 16121 | -0.297 | -0.1859 | Yes |
| 149 | Hdac3 | 16147 | -0.299 | -0.1809 | Yes |
| 150 | Mxd4 | 16295 | -0.308 | -0.1820 | Yes |
| 151 | Btg1 | 16308 | -0.309 | -0.1762 | Yes |
| 152 | Ppp1r15a | 16352 | -0.311 | -0.1719 | Yes |
| 153 | Zbtb16 | 16407 | -0.315 | -0.1681 | Yes |
| 154 | Iscu | 16473 | -0.320 | -0.1647 | Yes |
| 155 | Cdk5r1 | 16495 | -0.321 | -0.1591 | Yes |
| 156 | Rb1 | 16557 | -0.324 | -0.1555 | Yes |
| 157 | Pidd1 | 16558 | -0.324 | -0.1487 | Yes |
| 158 | Def6 | 16592 | -0.326 | -0.1436 | Yes |
| 159 | Pom121 | 16724 | -0.336 | -0.1433 | Yes |
| 160 | Btg2 | 16851 | -0.346 | -0.1425 | Yes |
| 161 | Gls2 | 17001 | -0.356 | -0.1427 | Yes |
| 162 | Cebpa | 17004 | -0.357 | -0.1354 | Yes |
| 163 | Tprkb | 17008 | -0.357 | -0.1281 | Yes |
| 164 | Gm2a | 17144 | -0.366 | -0.1273 | Yes |
| 165 | Ptpre | 17178 | -0.368 | -0.1214 | Yes |
| 166 | Ccnk | 17430 | -0.387 | -0.1261 | Yes |
| 167 | Irag2 | 17513 | -0.393 | -0.1221 | Yes |
| 168 | Retsat | 17651 | -0.403 | -0.1207 | Yes |
| 169 | Rack1 | 17711 | -0.410 | -0.1152 | Yes |
| 170 | Klk8 | 17792 | -0.418 | -0.1106 | Yes |
| 171 | Eps8l2 | 17844 | -0.422 | -0.1044 | Yes |
| 172 | Socs1 | 17910 | -0.429 | -0.0987 | Yes |
| 173 | Cd81 | 18050 | -0.443 | -0.0966 | Yes |
| 174 | Itgb4 | 18136 | -0.450 | -0.0916 | Yes |
| 175 | Pitpnc1 | 18203 | -0.459 | -0.0854 | Yes |
| 176 | Irak1 | 18309 | -0.473 | -0.0809 | Yes |
| 177 | Abhd4 | 18402 | -0.483 | -0.0755 | Yes |
| 178 | Fuca1 | 18573 | -0.508 | -0.0736 | Yes |
| 179 | Sertad3 | 18579 | -0.509 | -0.0633 | Yes |
| 180 | Notch1 | 18582 | -0.509 | -0.0528 | Yes |
| 181 | Ninj1 | 18645 | -0.519 | -0.0451 | Yes |
| 182 | Mxd1 | 18707 | -0.527 | -0.0372 | Yes |
| 183 | Ier3 | 18849 | -0.550 | -0.0330 | Yes |
| 184 | Ccnd3 | 18886 | -0.557 | -0.0232 | Yes |
| 185 | Ankra2 | 18892 | -0.558 | -0.0119 | Yes |
| 186 | Wrap73 | 19581 | -0.790 | -0.0305 | Yes |
| 187 | Tcn2 | 19606 | -0.819 | -0.0147 | Yes |
| 188 | Cgrrf1 | 19741 | -1.107 | 0.0015 | Yes |

