| Dataset | CMP.CMP_Pheno.cls#Group2_versus_Group4.CMP_Pheno.cls#Group2_versus_Group4_repos |
| Phenotype | CMP_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.51406807 |
| Normalized Enrichment Score (NES) | 1.933868 |
| Nominal p-value | 0.0038461538 |
| FDR q-value | 0.013627027 |
| FWER p-Value | 0.012 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Hspa8 | 6 | 1.169 | 0.0217 | Yes |
| 2 | Srsf1 | 101 | 0.870 | 0.0333 | Yes |
| 3 | Sqle | 119 | 0.830 | 0.0480 | Yes |
| 4 | Aurka | 175 | 0.775 | 0.0598 | Yes |
| 5 | Kpnb1 | 232 | 0.733 | 0.0707 | Yes |
| 6 | Hnrnpu | 262 | 0.719 | 0.0828 | Yes |
| 7 | Espl1 | 299 | 0.706 | 0.0943 | Yes |
| 8 | Tfdp1 | 463 | 0.641 | 0.0980 | Yes |
| 9 | Hnrnpd | 522 | 0.620 | 0.1067 | Yes |
| 10 | Cdc6 | 539 | 0.616 | 0.1175 | Yes |
| 11 | Xpo1 | 542 | 0.615 | 0.1290 | Yes |
| 12 | Bcl3 | 556 | 0.609 | 0.1398 | Yes |
| 13 | H2bc12 | 592 | 0.599 | 0.1493 | Yes |
| 14 | Smc1a | 605 | 0.597 | 0.1599 | Yes |
| 15 | Uck2 | 621 | 0.594 | 0.1703 | Yes |
| 16 | Kif2c | 644 | 0.588 | 0.1803 | Yes |
| 17 | Lbr | 645 | 0.588 | 0.1913 | Yes |
| 18 | Chaf1a | 702 | 0.574 | 0.1993 | Yes |
| 19 | Amd1 | 703 | 0.573 | 0.2101 | Yes |
| 20 | Sap30 | 758 | 0.561 | 0.2179 | Yes |
| 21 | Racgap1 | 772 | 0.559 | 0.2277 | Yes |
| 22 | Lmnb1 | 802 | 0.553 | 0.2367 | Yes |
| 23 | Prc1 | 818 | 0.550 | 0.2463 | Yes |
| 24 | Odc1 | 891 | 0.538 | 0.2527 | Yes |
| 25 | Upf1 | 897 | 0.537 | 0.2626 | Yes |
| 26 | Mcm2 | 983 | 0.522 | 0.2681 | Yes |
| 27 | Cdkn2c | 997 | 0.518 | 0.2771 | Yes |
| 28 | Chek1 | 1000 | 0.517 | 0.2868 | Yes |
| 29 | Rad21 | 1034 | 0.512 | 0.2947 | Yes |
| 30 | Top2a | 1055 | 0.507 | 0.3033 | Yes |
| 31 | Mcm5 | 1069 | 0.506 | 0.3121 | Yes |
| 32 | Incenp | 1175 | 0.492 | 0.3160 | Yes |
| 33 | Kif11 | 1267 | 0.480 | 0.3204 | Yes |
| 34 | H2az1 | 1304 | 0.476 | 0.3275 | Yes |
| 35 | Ncl | 1502 | 0.454 | 0.3260 | Yes |
| 36 | Meis2 | 1531 | 0.452 | 0.3331 | Yes |
| 37 | Sfpq | 1655 | 0.438 | 0.3351 | Yes |
| 38 | Nup50 | 1804 | 0.421 | 0.3354 | Yes |
| 39 | Ccna2 | 1814 | 0.420 | 0.3429 | Yes |
| 40 | Aurkb | 1818 | 0.419 | 0.3506 | Yes |
| 41 | Cdc25a | 1834 | 0.418 | 0.3577 | Yes |
| 42 | Hmmr | 1883 | 0.412 | 0.3630 | Yes |
| 43 | Cdc7 | 1897 | 0.411 | 0.3701 | Yes |
| 44 | Nasp | 1955 | 0.405 | 0.3748 | Yes |
| 45 | Dr1 | 1992 | 0.402 | 0.3806 | Yes |
| 46 | Cdk1 | 2014 | 0.400 | 0.3870 | Yes |
| 47 | Mki67 | 2126 | 0.388 | 0.3886 | Yes |
| 48 | Numa1 | 2183 | 0.382 | 0.3930 | Yes |
| 49 | Pbk | 2265 | 0.376 | 0.3959 | Yes |
| 50 | Kif15 | 2303 | 0.372 | 0.4010 | Yes |
| 51 | Ccnf | 2371 | 0.366 | 0.4045 | Yes |
| 52 | Mcm3 | 2572 | 0.353 | 0.4009 | Yes |
| 53 | Rad23b | 2609 | 0.350 | 0.4057 | Yes |
| 54 | Orc6 | 2613 | 0.350 | 0.4121 | Yes |
| 55 | G3bp1 | 2623 | 0.349 | 0.4183 | Yes |
| 56 | Kif4 | 2764 | 0.340 | 0.4175 | Yes |
| 57 | Atf5 | 2788 | 0.339 | 0.4227 | Yes |
| 58 | Pole | 2794 | 0.338 | 0.4288 | Yes |
| 59 | Nsd2 | 2813 | 0.337 | 0.4342 | Yes |
| 60 | Nek2 | 2842 | 0.335 | 0.4391 | Yes |
| 61 | Nolc1 | 2908 | 0.329 | 0.4420 | Yes |
| 62 | Ddx39a | 2945 | 0.327 | 0.4463 | Yes |
| 63 | Bub1 | 3009 | 0.323 | 0.4492 | Yes |
| 64 | Slc7a1 | 3021 | 0.322 | 0.4547 | Yes |
| 65 | Plk1 | 3084 | 0.319 | 0.4575 | Yes |
| 66 | Birc5 | 3085 | 0.319 | 0.4635 | Yes |
| 67 | Ccnt1 | 3126 | 0.318 | 0.4675 | Yes |
| 68 | Mcm6 | 3215 | 0.310 | 0.4688 | Yes |
| 69 | Tmpo | 3244 | 0.308 | 0.4732 | Yes |
| 70 | Tacc3 | 3291 | 0.304 | 0.4766 | Yes |
| 71 | Odf2 | 3303 | 0.303 | 0.4817 | Yes |
| 72 | Gspt1 | 3353 | 0.299 | 0.4848 | Yes |
| 73 | Cul1 | 3487 | 0.292 | 0.4835 | Yes |
| 74 | Ewsr1 | 3526 | 0.289 | 0.4870 | Yes |
| 75 | Cenpe | 3610 | 0.284 | 0.4881 | Yes |
| 76 | Smarcc1 | 3626 | 0.283 | 0.4927 | Yes |
| 77 | Tra2b | 3709 | 0.280 | 0.4938 | Yes |
| 78 | Ccnb2 | 3826 | 0.272 | 0.4929 | Yes |
| 79 | Kif23 | 3827 | 0.272 | 0.4981 | Yes |
| 80 | Fbxo5 | 3915 | 0.266 | 0.4986 | Yes |
| 81 | Cdc25b | 4126 | 0.252 | 0.4926 | Yes |
| 82 | Cks2 | 4133 | 0.252 | 0.4971 | Yes |
| 83 | Slc7a5 | 4156 | 0.250 | 0.5007 | Yes |
| 84 | Prim2 | 4206 | 0.247 | 0.5028 | Yes |
| 85 | Ss18 | 4409 | 0.234 | 0.4969 | Yes |
| 86 | Cenpf | 4492 | 0.229 | 0.4970 | Yes |
| 87 | Tent4a | 4498 | 0.229 | 0.5011 | Yes |
| 88 | Exo1 | 4788 | 0.213 | 0.4903 | Yes |
| 89 | Srsf10 | 4791 | 0.212 | 0.4942 | Yes |
| 90 | Suv39h1 | 4807 | 0.211 | 0.4974 | Yes |
| 91 | Pafah1b1 | 4967 | 0.203 | 0.4931 | Yes |
| 92 | Syncrip | 4997 | 0.201 | 0.4954 | Yes |
| 93 | Dbf4 | 5051 | 0.198 | 0.4964 | Yes |
| 94 | Pds5b | 5085 | 0.197 | 0.4985 | Yes |
| 95 | Cul5 | 5117 | 0.196 | 0.5006 | Yes |
| 96 | Rad54l | 5226 | 0.189 | 0.4986 | Yes |
| 97 | Smc4 | 5412 | 0.183 | 0.4926 | Yes |
| 98 | Stil | 5425 | 0.182 | 0.4954 | Yes |
| 99 | Smc2 | 5492 | 0.179 | 0.4954 | Yes |
| 100 | Rbl1 | 5495 | 0.178 | 0.4987 | Yes |
| 101 | Ube2s | 5521 | 0.177 | 0.5007 | Yes |
| 102 | Mtf2 | 5545 | 0.175 | 0.5029 | Yes |
| 103 | Cul3 | 5673 | 0.169 | 0.4995 | Yes |
| 104 | Polq | 5762 | 0.167 | 0.4982 | Yes |
| 105 | Nusap1 | 5831 | 0.164 | 0.4978 | Yes |
| 106 | Snrpd1 | 5837 | 0.163 | 0.5006 | Yes |
| 107 | E2f3 | 5839 | 0.163 | 0.5037 | Yes |
| 108 | Abl1 | 5841 | 0.163 | 0.5067 | Yes |
| 109 | Nup98 | 5842 | 0.163 | 0.5097 | Yes |
| 110 | Cdkn1b | 5879 | 0.162 | 0.5110 | Yes |
| 111 | Ilf3 | 5894 | 0.161 | 0.5133 | Yes |
| 112 | Ttk | 5938 | 0.159 | 0.5141 | Yes |
| 113 | Notch2 | 6107 | 0.149 | 0.5083 | No |
| 114 | Mybl2 | 6157 | 0.146 | 0.5085 | No |
| 115 | Pola2 | 6158 | 0.146 | 0.5113 | No |
| 116 | Mapk14 | 6456 | 0.133 | 0.4986 | No |
| 117 | Plk4 | 6467 | 0.133 | 0.5006 | No |
| 118 | Slc38a1 | 6566 | 0.129 | 0.4980 | No |
| 119 | Kif20b | 6624 | 0.126 | 0.4975 | No |
| 120 | Mad2l1 | 6703 | 0.121 | 0.4958 | No |
| 121 | Top1 | 6763 | 0.118 | 0.4950 | No |
| 122 | Dkc1 | 6899 | 0.112 | 0.4902 | No |
| 123 | Knl1 | 7002 | 0.107 | 0.4870 | No |
| 124 | Lig3 | 7148 | 0.100 | 0.4815 | No |
| 125 | Dmd | 7171 | 0.099 | 0.4822 | No |
| 126 | Cbx1 | 7417 | 0.088 | 0.4714 | No |
| 127 | Cdc27 | 7585 | 0.081 | 0.4644 | No |
| 128 | Prpf4b | 7876 | 0.068 | 0.4508 | No |
| 129 | Dtymk | 7933 | 0.066 | 0.4492 | No |
| 130 | Tpx2 | 7945 | 0.066 | 0.4499 | No |
| 131 | Jpt1 | 7993 | 0.064 | 0.4487 | No |
| 132 | Ezh2 | 8072 | 0.059 | 0.4458 | No |
| 133 | Kif5b | 8225 | 0.052 | 0.4390 | No |
| 134 | Ythdc1 | 8312 | 0.048 | 0.4356 | No |
| 135 | Prmt5 | 8326 | 0.048 | 0.4358 | No |
| 136 | Bard1 | 8360 | 0.046 | 0.4350 | No |
| 137 | Hif1a | 8427 | 0.043 | 0.4324 | No |
| 138 | Ctcf | 8532 | 0.038 | 0.4278 | No |
| 139 | Hira | 8638 | 0.034 | 0.4231 | No |
| 140 | Rpa2 | 8886 | 0.024 | 0.4109 | No |
| 141 | Atrx | 8900 | 0.023 | 0.4107 | No |
| 142 | Kif22 | 9057 | 0.017 | 0.4030 | No |
| 143 | Meis1 | 9090 | 0.016 | 0.4017 | No |
| 144 | Srsf2 | 9112 | 0.015 | 0.4009 | No |
| 145 | Ndc80 | 9136 | 0.014 | 0.4000 | No |
| 146 | Cdc45 | 9396 | 0.003 | 0.3868 | No |
| 147 | Stmn1 | 9431 | 0.002 | 0.3851 | No |
| 148 | Kmt5a | 9434 | 0.002 | 0.3851 | No |
| 149 | Ccnd1 | 9586 | -0.001 | 0.3774 | No |
| 150 | Cks1b | 9635 | -0.004 | 0.3750 | No |
| 151 | Orc5 | 9942 | -0.017 | 0.3597 | No |
| 152 | Arid4a | 10008 | -0.020 | 0.3567 | No |
| 153 | Hus1 | 10108 | -0.023 | 0.3521 | No |
| 154 | Stag1 | 10117 | -0.023 | 0.3521 | No |
| 155 | Smad3 | 10670 | -0.046 | 0.3248 | No |
| 156 | Slc12a2 | 10714 | -0.048 | 0.3235 | No |
| 157 | Fancc | 10799 | -0.052 | 0.3202 | No |
| 158 | Cul4a | 10868 | -0.055 | 0.3178 | No |
| 159 | Cdk4 | 11096 | -0.065 | 0.3074 | No |
| 160 | Mnat1 | 11099 | -0.065 | 0.3085 | No |
| 161 | Brca2 | 11105 | -0.065 | 0.3095 | No |
| 162 | Katna1 | 11456 | -0.078 | 0.2931 | No |
| 163 | Wrn | 11768 | -0.091 | 0.2789 | No |
| 164 | Hmgb3 | 11779 | -0.092 | 0.2801 | No |
| 165 | E2f2 | 11902 | -0.097 | 0.2757 | No |
| 166 | Tnpo2 | 11907 | -0.097 | 0.2774 | No |
| 167 | Bub3 | 12007 | -0.101 | 0.2742 | No |
| 168 | Rps6ka5 | 12010 | -0.102 | 0.2760 | No |
| 169 | Traip | 12166 | -0.109 | 0.2702 | No |
| 170 | Rasal2 | 12324 | -0.116 | 0.2643 | No |
| 171 | H2ax | 12401 | -0.119 | 0.2627 | No |
| 172 | Hmga1b | 12451 | -0.121 | 0.2625 | No |
| 173 | Tle3 | 12534 | -0.124 | 0.2606 | No |
| 174 | Map3k20 | 12555 | -0.125 | 0.2620 | No |
| 175 | H2az2 | 12984 | -0.145 | 0.2428 | No |
| 176 | Casp8ap2 | 13226 | -0.154 | 0.2334 | No |
| 177 | E2f4 | 13804 | -0.180 | 0.2073 | No |
| 178 | Myc | 14099 | -0.193 | 0.1959 | No |
| 179 | Cenpa | 14391 | -0.207 | 0.1850 | No |
| 180 | Chmp1a | 14619 | -0.218 | 0.1775 | No |
| 181 | Pml | 14691 | -0.221 | 0.1780 | No |
| 182 | Pura | 15206 | -0.248 | 0.1564 | No |
| 183 | Foxn3 | 15210 | -0.248 | 0.1609 | No |
| 184 | Ube2c | 15488 | -0.261 | 0.1517 | No |
| 185 | E2f1 | 15559 | -0.265 | 0.1531 | No |
| 186 | Tgfb1 | 15770 | -0.277 | 0.1476 | No |
| 187 | Efna5 | 16416 | -0.316 | 0.1206 | No |
| 188 | Egf | 16609 | -0.327 | 0.1170 | No |
| 189 | Cdc20 | 16804 | -0.342 | 0.1135 | No |
| 190 | Marcks | 16853 | -0.346 | 0.1176 | No |
| 191 | Troap | 17573 | -0.397 | 0.0883 | No |
| 192 | Pttg1 | 17631 | -0.401 | 0.0930 | No |
| 193 | Gins2 | 17686 | -0.408 | 0.0979 | No |
| 194 | Cdkn3 | 18177 | -0.455 | 0.0814 | No |

