| Dataset | CMP.CMP_Pheno.cls#Group2_versus_Group4.CMP_Pheno.cls#Group2_versus_Group4_repos |
| Phenotype | CMP_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.532292 |
| Normalized Enrichment Score (NES) | 1.9244541 |
| Nominal p-value | 0.007843138 |
| FDR q-value | 0.008607426 |
| FWER p-Value | 0.014 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ccp110 | 73 | 0.916 | 0.0133 | Yes |
| 2 | Srsf1 | 101 | 0.870 | 0.0282 | Yes |
| 3 | Aurka | 175 | 0.775 | 0.0389 | Yes |
| 4 | Dck | 261 | 0.720 | 0.0479 | Yes |
| 5 | Espl1 | 299 | 0.706 | 0.0592 | Yes |
| 6 | Ipo7 | 430 | 0.654 | 0.0647 | Yes |
| 7 | Rrm2 | 488 | 0.632 | 0.0736 | Yes |
| 8 | Hnrnpd | 522 | 0.620 | 0.0834 | Yes |
| 9 | Xpo1 | 542 | 0.615 | 0.0939 | Yes |
| 10 | Smc1a | 605 | 0.597 | 0.1019 | Yes |
| 11 | Kif2c | 644 | 0.588 | 0.1109 | Yes |
| 12 | Lbr | 645 | 0.588 | 0.1218 | Yes |
| 13 | Ssrp1 | 656 | 0.584 | 0.1322 | Yes |
| 14 | Rbbp7 | 691 | 0.576 | 0.1412 | Yes |
| 15 | Cse1l | 741 | 0.565 | 0.1492 | Yes |
| 16 | Bub1b | 766 | 0.560 | 0.1584 | Yes |
| 17 | Racgap1 | 772 | 0.559 | 0.1686 | Yes |
| 18 | Spc25 | 797 | 0.554 | 0.1777 | Yes |
| 19 | Lmnb1 | 802 | 0.553 | 0.1878 | Yes |
| 20 | Mcm4 | 862 | 0.543 | 0.1949 | Yes |
| 21 | Anp32e | 868 | 0.542 | 0.2047 | Yes |
| 22 | Dnmt1 | 948 | 0.530 | 0.2105 | Yes |
| 23 | Mcm2 | 983 | 0.522 | 0.2185 | Yes |
| 24 | Cdkn2c | 997 | 0.518 | 0.2275 | Yes |
| 25 | Chek1 | 1000 | 0.517 | 0.2370 | Yes |
| 26 | Rad51ap1 | 1017 | 0.515 | 0.2458 | Yes |
| 27 | Ccne1 | 1022 | 0.514 | 0.2552 | Yes |
| 28 | Rad21 | 1034 | 0.512 | 0.2641 | Yes |
| 29 | Top2a | 1055 | 0.507 | 0.2725 | Yes |
| 30 | Mcm5 | 1069 | 0.506 | 0.2813 | Yes |
| 31 | Brca1 | 1225 | 0.486 | 0.2824 | Yes |
| 32 | Shmt1 | 1278 | 0.478 | 0.2887 | Yes |
| 33 | H2az1 | 1304 | 0.476 | 0.2963 | Yes |
| 34 | Nup107 | 1380 | 0.467 | 0.3011 | Yes |
| 35 | Slbp | 1402 | 0.465 | 0.3087 | Yes |
| 36 | Prdx4 | 1486 | 0.457 | 0.3130 | Yes |
| 37 | Tubb5 | 1614 | 0.444 | 0.3148 | Yes |
| 38 | Cbx5 | 1628 | 0.441 | 0.3223 | Yes |
| 39 | Hells | 1720 | 0.431 | 0.3257 | Yes |
| 40 | Prps1 | 1798 | 0.422 | 0.3296 | Yes |
| 41 | Aurkb | 1818 | 0.419 | 0.3365 | Yes |
| 42 | Cdc25a | 1834 | 0.418 | 0.3435 | Yes |
| 43 | Ncapd2 | 1858 | 0.415 | 0.3500 | Yes |
| 44 | Hmmr | 1883 | 0.412 | 0.3565 | Yes |
| 45 | Smc3 | 1896 | 0.411 | 0.3635 | Yes |
| 46 | Nasp | 1955 | 0.405 | 0.3681 | Yes |
| 47 | Melk | 2000 | 0.401 | 0.3733 | Yes |
| 48 | Cdk1 | 2014 | 0.400 | 0.3801 | Yes |
| 49 | Atad2 | 2089 | 0.392 | 0.3836 | Yes |
| 50 | Mki67 | 2126 | 0.388 | 0.3890 | Yes |
| 51 | Cdkn1a | 2287 | 0.374 | 0.3878 | Yes |
| 52 | Nup205 | 2355 | 0.368 | 0.3912 | Yes |
| 53 | Dlgap5 | 2470 | 0.360 | 0.3921 | Yes |
| 54 | Paics | 2482 | 0.359 | 0.3982 | Yes |
| 55 | Mcm3 | 2572 | 0.353 | 0.4003 | Yes |
| 56 | Orc6 | 2613 | 0.350 | 0.4048 | Yes |
| 57 | Kif4 | 2764 | 0.340 | 0.4034 | Yes |
| 58 | Rad1 | 2786 | 0.339 | 0.4087 | Yes |
| 59 | Pole | 2794 | 0.338 | 0.4146 | Yes |
| 60 | Timeless | 2801 | 0.338 | 0.4206 | Yes |
| 61 | Nolc1 | 2908 | 0.329 | 0.4213 | Yes |
| 62 | Nop56 | 2937 | 0.328 | 0.4260 | Yes |
| 63 | Ddx39a | 2945 | 0.327 | 0.4317 | Yes |
| 64 | Nap1l1 | 3003 | 0.323 | 0.4348 | Yes |
| 65 | Donson | 3035 | 0.321 | 0.4392 | Yes |
| 66 | Plk1 | 3084 | 0.319 | 0.4427 | Yes |
| 67 | Birc5 | 3085 | 0.319 | 0.4487 | Yes |
| 68 | Psip1 | 3129 | 0.317 | 0.4524 | Yes |
| 69 | Xrcc6 | 3180 | 0.313 | 0.4557 | Yes |
| 70 | Mcm6 | 3215 | 0.310 | 0.4597 | Yes |
| 71 | Tmpo | 3244 | 0.308 | 0.4640 | Yes |
| 72 | Ubr7 | 3267 | 0.305 | 0.4686 | Yes |
| 73 | Pa2g4 | 3276 | 0.304 | 0.4738 | Yes |
| 74 | Tacc3 | 3291 | 0.304 | 0.4788 | Yes |
| 75 | Mcm7 | 3346 | 0.299 | 0.4816 | Yes |
| 76 | Gspt1 | 3353 | 0.299 | 0.4868 | Yes |
| 77 | Tk1 | 3457 | 0.294 | 0.4871 | Yes |
| 78 | Cdca8 | 3482 | 0.292 | 0.4913 | Yes |
| 79 | Cnot9 | 3514 | 0.290 | 0.4951 | Yes |
| 80 | Cenpe | 3610 | 0.284 | 0.4955 | Yes |
| 81 | Lsm8 | 3617 | 0.283 | 0.5005 | Yes |
| 82 | Tra2b | 3709 | 0.280 | 0.5010 | Yes |
| 83 | Ccnb2 | 3826 | 0.272 | 0.5002 | Yes |
| 84 | Cit | 4002 | 0.260 | 0.4961 | Yes |
| 85 | Lyar | 4005 | 0.260 | 0.5008 | Yes |
| 86 | Phf5a | 4013 | 0.260 | 0.5053 | Yes |
| 87 | Wdr90 | 4063 | 0.256 | 0.5076 | Yes |
| 88 | Ranbp1 | 4101 | 0.253 | 0.5104 | Yes |
| 89 | Cdc25b | 4126 | 0.252 | 0.5139 | Yes |
| 90 | Cks2 | 4133 | 0.252 | 0.5182 | Yes |
| 91 | Prim2 | 4206 | 0.247 | 0.5192 | Yes |
| 92 | Tfrc | 4236 | 0.244 | 0.5222 | Yes |
| 93 | Nup153 | 4291 | 0.241 | 0.5240 | Yes |
| 94 | Lig1 | 4466 | 0.230 | 0.5194 | Yes |
| 95 | Msh2 | 4604 | 0.223 | 0.5165 | Yes |
| 96 | Rpa1 | 4703 | 0.218 | 0.5156 | Yes |
| 97 | Rfc1 | 4716 | 0.218 | 0.5190 | Yes |
| 98 | Nme1 | 4758 | 0.214 | 0.5209 | Yes |
| 99 | Eif2s1 | 4792 | 0.212 | 0.5232 | Yes |
| 100 | Zw10 | 4794 | 0.212 | 0.5271 | Yes |
| 101 | Suv39h1 | 4807 | 0.211 | 0.5304 | Yes |
| 102 | Ube2t | 4858 | 0.209 | 0.5317 | Yes |
| 103 | Kif18b | 4947 | 0.204 | 0.5310 | Yes |
| 104 | Syncrip | 4997 | 0.201 | 0.5323 | Yes |
| 105 | Pds5b | 5085 | 0.197 | 0.5315 | No |
| 106 | Smc4 | 5412 | 0.183 | 0.5183 | No |
| 107 | Pcna | 5427 | 0.182 | 0.5209 | No |
| 108 | Wee1 | 5511 | 0.177 | 0.5200 | No |
| 109 | Ube2s | 5521 | 0.177 | 0.5228 | No |
| 110 | Prkdc | 5823 | 0.164 | 0.5105 | No |
| 111 | Cdkn1b | 5879 | 0.162 | 0.5107 | No |
| 112 | Gins3 | 5892 | 0.161 | 0.5131 | No |
| 113 | Ilf3 | 5894 | 0.161 | 0.5161 | No |
| 114 | Spag5 | 6004 | 0.155 | 0.5134 | No |
| 115 | Tbrg4 | 6045 | 0.153 | 0.5142 | No |
| 116 | Rad51c | 6074 | 0.151 | 0.5155 | No |
| 117 | Mre11a | 6102 | 0.149 | 0.5169 | No |
| 118 | Mybl2 | 6157 | 0.146 | 0.5169 | No |
| 119 | Pola2 | 6158 | 0.146 | 0.5196 | No |
| 120 | Ak2 | 6337 | 0.139 | 0.5131 | No |
| 121 | Plk4 | 6467 | 0.133 | 0.5090 | No |
| 122 | Mad2l1 | 6703 | 0.121 | 0.4993 | No |
| 123 | E2f8 | 6911 | 0.111 | 0.4908 | No |
| 124 | Gins4 | 6994 | 0.107 | 0.4886 | No |
| 125 | Pms2 | 7050 | 0.105 | 0.4877 | No |
| 126 | Diaph3 | 7259 | 0.096 | 0.4789 | No |
| 127 | Asf1a | 7290 | 0.094 | 0.4791 | No |
| 128 | Ran | 7513 | 0.084 | 0.4693 | No |
| 129 | Tipin | 7603 | 0.080 | 0.4662 | No |
| 130 | Pnn | 7785 | 0.072 | 0.4583 | No |
| 131 | Dut | 7836 | 0.070 | 0.4571 | No |
| 132 | Jpt1 | 7993 | 0.064 | 0.4503 | No |
| 133 | Ezh2 | 8072 | 0.059 | 0.4474 | No |
| 134 | Mms22l | 8164 | 0.054 | 0.4438 | No |
| 135 | Trip13 | 8206 | 0.053 | 0.4427 | No |
| 136 | Pole4 | 8289 | 0.050 | 0.4394 | No |
| 137 | Eed | 8339 | 0.047 | 0.4378 | No |
| 138 | Bard1 | 8360 | 0.046 | 0.4376 | No |
| 139 | Ctcf | 8532 | 0.038 | 0.4296 | No |
| 140 | Ung | 8579 | 0.036 | 0.4279 | No |
| 141 | Orc2 | 8580 | 0.036 | 0.4286 | No |
| 142 | Dscc1 | 8688 | 0.032 | 0.4237 | No |
| 143 | Mlh1 | 8693 | 0.032 | 0.4241 | No |
| 144 | Usp1 | 8845 | 0.025 | 0.4168 | No |
| 145 | Rpa2 | 8886 | 0.024 | 0.4152 | No |
| 146 | Ppp1r8 | 9005 | 0.019 | 0.4096 | No |
| 147 | Kif22 | 9057 | 0.017 | 0.4073 | No |
| 148 | Mthfd2 | 9109 | 0.015 | 0.4049 | No |
| 149 | Srsf2 | 9112 | 0.015 | 0.4051 | No |
| 150 | Hmgb2 | 9223 | 0.011 | 0.3997 | No |
| 151 | Tubg1 | 9354 | 0.005 | 0.3931 | No |
| 152 | Rad50 | 9419 | 0.002 | 0.3899 | No |
| 153 | Stmn1 | 9431 | 0.002 | 0.3894 | No |
| 154 | Dek | 9439 | 0.002 | 0.3891 | No |
| 155 | Dctpp1 | 9614 | -0.003 | 0.3802 | No |
| 156 | Cks1b | 9635 | -0.004 | 0.3793 | No |
| 157 | Chek2 | 9679 | -0.006 | 0.3772 | No |
| 158 | Rpa3 | 9998 | -0.019 | 0.3613 | No |
| 159 | Nbn | 10083 | -0.022 | 0.3574 | No |
| 160 | Hus1 | 10108 | -0.023 | 0.3566 | No |
| 161 | Asf1b | 10115 | -0.023 | 0.3568 | No |
| 162 | Stag1 | 10117 | -0.023 | 0.3571 | No |
| 163 | Trp53 | 10559 | -0.043 | 0.3354 | No |
| 164 | Smc6 | 10927 | -0.058 | 0.3177 | No |
| 165 | Cdk4 | 11096 | -0.065 | 0.3104 | No |
| 166 | Brca2 | 11105 | -0.065 | 0.3112 | No |
| 167 | Rnaseh2a | 11217 | -0.068 | 0.3068 | No |
| 168 | Nudt21 | 11227 | -0.069 | 0.3076 | No |
| 169 | Pold3 | 11754 | -0.090 | 0.2824 | No |
| 170 | Hmgb3 | 11779 | -0.092 | 0.2829 | No |
| 171 | Luc7l3 | 11892 | -0.097 | 0.2789 | No |
| 172 | Cdkn2a | 12328 | -0.116 | 0.2589 | No |
| 173 | Rfc2 | 12374 | -0.118 | 0.2588 | No |
| 174 | H2ax | 12401 | -0.119 | 0.2597 | No |
| 175 | Hmga1b | 12451 | -0.121 | 0.2594 | No |
| 176 | Ing3 | 12667 | -0.131 | 0.2509 | No |
| 177 | Exosc8 | 12854 | -0.140 | 0.2440 | No |
| 178 | Brms1l | 12980 | -0.145 | 0.2403 | No |
| 179 | Gins1 | 13094 | -0.149 | 0.2373 | No |
| 180 | Tcf19 | 13261 | -0.156 | 0.2317 | No |
| 181 | Myc | 14099 | -0.193 | 0.1926 | No |
| 182 | Pold1 | 14354 | -0.205 | 0.1834 | No |
| 183 | Mxd3 | 14435 | -0.209 | 0.1832 | No |
| 184 | Rfc3 | 14565 | -0.215 | 0.1806 | No |
| 185 | Spc24 | 14998 | -0.237 | 0.1629 | No |
| 186 | Pop7 | 15213 | -0.248 | 0.1566 | No |
| 187 | Ppm1d | 15475 | -0.261 | 0.1482 | No |
| 188 | Psmc3ip | 15529 | -0.264 | 0.1504 | No |
| 189 | Pold2 | 15653 | -0.270 | 0.1491 | No |
| 190 | Depdc1a | 15723 | -0.274 | 0.1507 | No |
| 191 | Dclre1b | 15764 | -0.276 | 0.1538 | No |
| 192 | Snrpb | 16166 | -0.300 | 0.1389 | No |
| 193 | Cdc20 | 16804 | -0.342 | 0.1127 | No |
| 194 | Cdca3 | 17080 | -0.362 | 0.1054 | No |
| 195 | Pan2 | 17402 | -0.384 | 0.0961 | No |
| 196 | Pttg1 | 17631 | -0.401 | 0.0920 | No |
| 197 | Cdkn3 | 18177 | -0.455 | 0.0726 | No |
| 198 | Cenpm | 18298 | -0.471 | 0.0753 | No |

