| Dataset | CMP.CMP_Pheno.cls#Group2_versus_Group4.CMP_Pheno.cls#Group2_versus_Group4_repos |
| Phenotype | CMP_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | -0.19608861 |
| Normalized Enrichment Score (NES) | -0.8902379 |
| Nominal p-value | 0.6266925 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.996 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Akt1 | 103 | 0.864 | 0.0162 | No |
| 2 | Ccr5 | 204 | 0.751 | 0.0298 | No |
| 3 | Cd80 | 433 | 0.652 | 0.0344 | No |
| 4 | Ccr2 | 493 | 0.630 | 0.0470 | No |
| 5 | Ets1 | 540 | 0.615 | 0.0600 | No |
| 6 | Bcl3 | 556 | 0.609 | 0.0744 | No |
| 7 | Bcat1 | 686 | 0.577 | 0.0821 | No |
| 8 | Il7 | 899 | 0.537 | 0.0847 | No |
| 9 | Icam1 | 1204 | 0.489 | 0.0813 | No |
| 10 | Brca1 | 1225 | 0.486 | 0.0924 | No |
| 11 | Il2rg | 1301 | 0.476 | 0.1004 | No |
| 12 | Crtam | 1396 | 0.465 | 0.1072 | No |
| 13 | Abce1 | 1492 | 0.456 | 0.1137 | No |
| 14 | Fas | 1619 | 0.442 | 0.1182 | No |
| 15 | Zap70 | 1686 | 0.433 | 0.1256 | No |
| 16 | Eif3j1 | 1825 | 0.419 | 0.1290 | No |
| 17 | Il18rap | 1846 | 0.417 | 0.1384 | No |
| 18 | Traf2 | 2110 | 0.390 | 0.1346 | No |
| 19 | Galnt1 | 2217 | 0.379 | 0.1386 | No |
| 20 | Il27ra | 2244 | 0.377 | 0.1467 | No |
| 21 | Eif3a | 2284 | 0.374 | 0.1540 | No |
| 22 | Il4ra | 2435 | 0.361 | 0.1553 | No |
| 23 | Mmp9 | 2446 | 0.361 | 0.1638 | No |
| 24 | Il2ra | 2492 | 0.358 | 0.1704 | No |
| 25 | Ly75 | 2544 | 0.355 | 0.1766 | No |
| 26 | Ube2n | 2601 | 0.351 | 0.1825 | No |
| 27 | Thy1 | 3087 | 0.319 | 0.1657 | No |
| 28 | F2r | 3279 | 0.304 | 0.1635 | No |
| 29 | Prkcg | 3386 | 0.297 | 0.1655 | No |
| 30 | Ccr1 | 3496 | 0.291 | 0.1672 | No |
| 31 | Il12a | 3557 | 0.287 | 0.1713 | No |
| 32 | Map4k1 | 3616 | 0.283 | 0.1754 | No |
| 33 | Dyrk3 | 3628 | 0.282 | 0.1818 | No |
| 34 | Irf4 | 3737 | 0.278 | 0.1832 | No |
| 35 | Mrpl3 | 3802 | 0.274 | 0.1868 | No |
| 36 | Nme1 | 4758 | 0.214 | 0.1434 | No |
| 37 | Il1b | 4873 | 0.208 | 0.1428 | No |
| 38 | Wars1 | 4927 | 0.205 | 0.1452 | No |
| 39 | C2 | 4958 | 0.204 | 0.1487 | No |
| 40 | Itgb2 | 5644 | 0.170 | 0.1180 | No |
| 41 | Map3k7 | 5921 | 0.160 | 0.1079 | No |
| 42 | Acvr2a | 5949 | 0.158 | 0.1105 | No |
| 43 | Tapbp | 6118 | 0.149 | 0.1056 | No |
| 44 | Tnf | 6385 | 0.137 | 0.0954 | No |
| 45 | H2-Oa | 6397 | 0.136 | 0.0983 | No |
| 46 | Tpd52 | 6448 | 0.134 | 0.0990 | No |
| 47 | Fcgr2b | 6737 | 0.120 | 0.0873 | No |
| 48 | Hcls1 | 6882 | 0.113 | 0.0828 | No |
| 49 | Apbb1 | 6926 | 0.110 | 0.0833 | No |
| 50 | Rpl9 | 7055 | 0.104 | 0.0794 | No |
| 51 | Il18 | 7062 | 0.104 | 0.0817 | No |
| 52 | Bcl10 | 7118 | 0.102 | 0.0814 | No |
| 53 | Was | 7155 | 0.100 | 0.0821 | No |
| 54 | Ctss | 7165 | 0.099 | 0.0841 | No |
| 55 | Flna | 7439 | 0.087 | 0.0723 | No |
| 56 | Abi1 | 7523 | 0.083 | 0.0702 | No |
| 57 | Jak2 | 7579 | 0.081 | 0.0694 | No |
| 58 | Npm1 | 7787 | 0.072 | 0.0606 | No |
| 59 | Ripk2 | 8062 | 0.060 | 0.0481 | No |
| 60 | Tap1 | 8190 | 0.053 | 0.0430 | No |
| 61 | Cd247 | 8268 | 0.050 | 0.0403 | No |
| 62 | Cd47 | 8269 | 0.050 | 0.0416 | No |
| 63 | H2-DMb2 | 8355 | 0.046 | 0.0384 | No |
| 64 | Nck1 | 8410 | 0.044 | 0.0367 | No |
| 65 | Hif1a | 8427 | 0.043 | 0.0370 | No |
| 66 | Ccl5 | 8515 | 0.039 | 0.0335 | No |
| 67 | Cd79a | 8649 | 0.034 | 0.0276 | No |
| 68 | Ptprc | 8703 | 0.031 | 0.0257 | No |
| 69 | Eif3d | 8737 | 0.030 | 0.0247 | No |
| 70 | Gpr65 | 8771 | 0.029 | 0.0238 | No |
| 71 | Lcp2 | 8952 | 0.021 | 0.0151 | No |
| 72 | Rpl3l | 9249 | 0.010 | 0.0003 | No |
| 73 | Tgfb2 | 9361 | 0.004 | -0.0053 | No |
| 74 | Egfr | 9488 | 0.000 | -0.0117 | No |
| 75 | Eif4g3 | 9824 | -0.011 | -0.0285 | No |
| 76 | Itk | 9829 | -0.011 | -0.0284 | No |
| 77 | Csk | 9924 | -0.016 | -0.0328 | No |
| 78 | Ltb | 10142 | -0.025 | -0.0433 | No |
| 79 | St8sia4 | 10344 | -0.033 | -0.0527 | No |
| 80 | Trat1 | 10411 | -0.036 | -0.0551 | No |
| 81 | Ache | 10427 | -0.037 | -0.0550 | No |
| 82 | Il4 | 10464 | -0.039 | -0.0559 | No |
| 83 | Hdac9 | 10704 | -0.048 | -0.0668 | No |
| 84 | Ifngr1 | 10754 | -0.050 | -0.0681 | No |
| 85 | Stab1 | 10830 | -0.053 | -0.0706 | No |
| 86 | Fgr | 10966 | -0.060 | -0.0760 | No |
| 87 | H2-Ob | 11301 | -0.072 | -0.0912 | No |
| 88 | H2-Aa | 11332 | -0.073 | -0.0910 | No |
| 89 | Nlrp3 | 11359 | -0.074 | -0.0905 | No |
| 90 | Csf1 | 11360 | -0.074 | -0.0886 | No |
| 91 | Tlr1 | 11377 | -0.075 | -0.0876 | No |
| 92 | Srgn | 11502 | -0.080 | -0.0919 | No |
| 93 | Degs1 | 11758 | -0.091 | -0.1027 | No |
| 94 | Il2 | 12087 | -0.105 | -0.1168 | No |
| 95 | Cdkn2a | 12328 | -0.116 | -0.1261 | No |
| 96 | Icosl | 12373 | -0.118 | -0.1254 | No |
| 97 | Cd86 | 12467 | -0.122 | -0.1271 | No |
| 98 | Ptpn6 | 12557 | -0.126 | -0.1286 | No |
| 99 | Stat1 | 12681 | -0.132 | -0.1315 | No |
| 100 | Lyn | 12686 | -0.132 | -0.1285 | No |
| 101 | Inhba | 12770 | -0.135 | -0.1293 | No |
| 102 | Lck | 12895 | -0.142 | -0.1321 | No |
| 103 | Itgal | 13020 | -0.146 | -0.1348 | No |
| 104 | Tlr3 | 13307 | -0.158 | -0.1455 | No |
| 105 | Gcnt1 | 13326 | -0.158 | -0.1424 | No |
| 106 | Ccnd2 | 13537 | -0.169 | -0.1489 | No |
| 107 | Il6 | 13602 | -0.172 | -0.1479 | No |
| 108 | Capg | 13706 | -0.175 | -0.1488 | No |
| 109 | Glmn | 13951 | -0.186 | -0.1566 | No |
| 110 | Rps3a1 | 13992 | -0.189 | -0.1540 | No |
| 111 | Tlr2 | 14787 | -0.226 | -0.1888 | No |
| 112 | Rps9 | 14886 | -0.231 | -0.1881 | No |
| 113 | Il12rb1 | 14971 | -0.235 | -0.1865 | No |
| 114 | Ikbkb | 15037 | -0.238 | -0.1839 | No |
| 115 | B2m | 15073 | -0.240 | -0.1797 | No |
| 116 | Cxcl9 | 15177 | -0.246 | -0.1788 | No |
| 117 | Lif | 15384 | -0.256 | -0.1830 | No |
| 118 | Cd74 | 15453 | -0.260 | -0.1800 | No |
| 119 | Tgfb1 | 15770 | -0.277 | -0.1892 | Yes |
| 120 | Eif5a | 15819 | -0.279 | -0.1847 | Yes |
| 121 | Ifngr2 | 15944 | -0.286 | -0.1839 | Yes |
| 122 | Stat4 | 15945 | -0.286 | -0.1768 | Yes |
| 123 | Cd96 | 15960 | -0.287 | -0.1704 | Yes |
| 124 | Socs5 | 16095 | -0.295 | -0.1699 | Yes |
| 125 | Ifnar2 | 16529 | -0.323 | -0.1839 | Yes |
| 126 | Cd1d2 | 16587 | -0.326 | -0.1787 | Yes |
| 127 | Tlr6 | 16647 | -0.330 | -0.1735 | Yes |
| 128 | Mtif2 | 16833 | -0.344 | -0.1744 | Yes |
| 129 | Psmb10 | 16932 | -0.352 | -0.1707 | Yes |
| 130 | Tap2 | 16992 | -0.355 | -0.1648 | Yes |
| 131 | Il10 | 17234 | -0.372 | -0.1679 | Yes |
| 132 | Il11 | 17349 | -0.380 | -0.1642 | Yes |
| 133 | Ube2d1 | 17815 | -0.419 | -0.1775 | Yes |
| 134 | Socs1 | 17910 | -0.429 | -0.1716 | Yes |
| 135 | Irf7 | 17912 | -0.430 | -0.1610 | Yes |
| 136 | Cfp | 18301 | -0.471 | -0.1690 | Yes |
| 137 | Il16 | 18368 | -0.479 | -0.1605 | Yes |
| 138 | Elf4 | 18578 | -0.508 | -0.1585 | Yes |
| 139 | Cd28 | 18654 | -0.521 | -0.1494 | Yes |
| 140 | Spi1 | 18718 | -0.529 | -0.1395 | Yes |
| 141 | Igsf6 | 18854 | -0.551 | -0.1327 | Yes |
| 142 | Ccnd3 | 18886 | -0.557 | -0.1204 | Yes |
| 143 | Cd4 | 18888 | -0.557 | -0.1066 | Yes |
| 144 | Il15 | 19169 | -0.616 | -0.1056 | Yes |
| 145 | Elane | 19206 | -0.626 | -0.0918 | Yes |
| 146 | Ly86 | 19237 | -0.636 | -0.0776 | Yes |
| 147 | Ncf4 | 19295 | -0.656 | -0.0642 | Yes |
| 148 | Irf8 | 19438 | -0.706 | -0.0539 | Yes |
| 149 | Prkcb | 19458 | -0.714 | -0.0371 | Yes |
| 150 | H2-DMa | 19678 | -0.915 | -0.0255 | Yes |
| 151 | Pf4 | 19753 | -1.215 | 0.0009 | Yes |

