| Dataset | CMP.CMP_Pheno.cls#Group2_versus_Group3.CMP_Pheno.cls#Group2_versus_Group3_repos |
| Phenotype | CMP_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.52508265 |
| Normalized Enrichment Score (NES) | 1.888757 |
| Nominal p-value | 0.021696253 |
| FDR q-value | 0.026508514 |
| FWER p-Value | 0.024 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Hspa8 | 20 | 1.016 | 0.0199 | Yes |
| 2 | Srsf1 | 90 | 0.786 | 0.0325 | Yes |
| 3 | Kpnb1 | 247 | 0.673 | 0.0384 | Yes |
| 4 | Hnrnpu | 339 | 0.632 | 0.0468 | Yes |
| 5 | Lbr | 415 | 0.598 | 0.0553 | Yes |
| 6 | Espl1 | 489 | 0.577 | 0.0634 | Yes |
| 7 | Smc1a | 505 | 0.571 | 0.0744 | Yes |
| 8 | Cdc6 | 586 | 0.549 | 0.0816 | Yes |
| 9 | Chaf1a | 598 | 0.546 | 0.0923 | Yes |
| 10 | Bcl3 | 633 | 0.539 | 0.1016 | Yes |
| 11 | Xpo1 | 646 | 0.537 | 0.1121 | Yes |
| 12 | Lmnb1 | 649 | 0.537 | 0.1231 | Yes |
| 13 | Tfdp1 | 688 | 0.528 | 0.1320 | Yes |
| 14 | Hnrnpd | 713 | 0.524 | 0.1415 | Yes |
| 15 | Ncl | 829 | 0.500 | 0.1460 | Yes |
| 16 | Aurkb | 866 | 0.492 | 0.1543 | Yes |
| 17 | Kif4 | 935 | 0.482 | 0.1607 | Yes |
| 18 | Ccna2 | 939 | 0.481 | 0.1705 | Yes |
| 19 | Dr1 | 953 | 0.479 | 0.1797 | Yes |
| 20 | Nasp | 1088 | 0.460 | 0.1823 | Yes |
| 21 | Pbk | 1099 | 0.457 | 0.1912 | Yes |
| 22 | Top2a | 1162 | 0.450 | 0.1973 | Yes |
| 23 | Bub1 | 1178 | 0.448 | 0.2057 | Yes |
| 24 | Prc1 | 1191 | 0.447 | 0.2143 | Yes |
| 25 | Odc1 | 1205 | 0.446 | 0.2229 | Yes |
| 26 | Incenp | 1277 | 0.437 | 0.2282 | Yes |
| 27 | Cdk1 | 1292 | 0.434 | 0.2365 | Yes |
| 28 | Kif15 | 1405 | 0.423 | 0.2395 | Yes |
| 29 | Tpx2 | 1520 | 0.407 | 0.2420 | Yes |
| 30 | H2az1 | 1588 | 0.398 | 0.2468 | Yes |
| 31 | Hmmr | 1597 | 0.396 | 0.2545 | Yes |
| 32 | Nup50 | 1613 | 0.395 | 0.2619 | Yes |
| 33 | Kif11 | 1635 | 0.392 | 0.2689 | Yes |
| 34 | Tacc3 | 1636 | 0.392 | 0.2770 | Yes |
| 35 | Nolc1 | 1642 | 0.391 | 0.2848 | Yes |
| 36 | Fbxo5 | 1651 | 0.390 | 0.2924 | Yes |
| 37 | Aurka | 1692 | 0.386 | 0.2983 | Yes |
| 38 | Racgap1 | 1694 | 0.386 | 0.3062 | Yes |
| 39 | Nsd2 | 1760 | 0.379 | 0.3107 | Yes |
| 40 | Birc5 | 1784 | 0.378 | 0.3173 | Yes |
| 41 | Mybl2 | 1787 | 0.377 | 0.3249 | Yes |
| 42 | Uck2 | 1809 | 0.374 | 0.3316 | Yes |
| 43 | Atf5 | 1847 | 0.370 | 0.3373 | Yes |
| 44 | Mki67 | 1869 | 0.369 | 0.3438 | Yes |
| 45 | Cdc25a | 1870 | 0.368 | 0.3514 | Yes |
| 46 | Rad21 | 1901 | 0.367 | 0.3574 | Yes |
| 47 | Dbf4 | 1906 | 0.366 | 0.3648 | Yes |
| 48 | Cdc7 | 2155 | 0.347 | 0.3592 | Yes |
| 49 | Upf1 | 2181 | 0.344 | 0.3650 | Yes |
| 50 | Cdkn1b | 2204 | 0.343 | 0.3710 | Yes |
| 51 | Ttk | 2250 | 0.340 | 0.3757 | Yes |
| 52 | E2f3 | 2286 | 0.338 | 0.3808 | Yes |
| 53 | Ilf3 | 2371 | 0.331 | 0.3834 | Yes |
| 54 | Sap30 | 2386 | 0.330 | 0.3894 | Yes |
| 55 | Mad2l1 | 2391 | 0.329 | 0.3960 | Yes |
| 56 | Numa1 | 2621 | 0.315 | 0.3908 | Yes |
| 57 | Ndc80 | 2631 | 0.314 | 0.3968 | Yes |
| 58 | Mcm3 | 2643 | 0.312 | 0.4027 | Yes |
| 59 | Mcm2 | 2674 | 0.310 | 0.4075 | Yes |
| 60 | Ccnf | 2705 | 0.308 | 0.4123 | Yes |
| 61 | Sfpq | 2845 | 0.298 | 0.4113 | Yes |
| 62 | Prmt5 | 2850 | 0.297 | 0.4173 | Yes |
| 63 | Kif20b | 2870 | 0.296 | 0.4224 | Yes |
| 64 | Plk4 | 2929 | 0.293 | 0.4254 | Yes |
| 65 | Cenpe | 2966 | 0.290 | 0.4296 | Yes |
| 66 | H2bc12 | 2974 | 0.289 | 0.4352 | Yes |
| 67 | Cdkn2c | 2977 | 0.289 | 0.4410 | Yes |
| 68 | Ccnt1 | 3000 | 0.288 | 0.4458 | Yes |
| 69 | Kif22 | 3010 | 0.287 | 0.4513 | Yes |
| 70 | Rad23b | 3013 | 0.287 | 0.4571 | Yes |
| 71 | Cdc25b | 3084 | 0.282 | 0.4593 | Yes |
| 72 | Top1 | 3173 | 0.278 | 0.4605 | Yes |
| 73 | E2f4 | 3214 | 0.275 | 0.4642 | Yes |
| 74 | Cul1 | 3282 | 0.271 | 0.4663 | Yes |
| 75 | G3bp1 | 3308 | 0.270 | 0.4706 | Yes |
| 76 | Cenpf | 3319 | 0.269 | 0.4756 | Yes |
| 77 | Lig3 | 3382 | 0.264 | 0.4779 | Yes |
| 78 | Amd1 | 3403 | 0.263 | 0.4823 | Yes |
| 79 | Smc2 | 3458 | 0.261 | 0.4849 | Yes |
| 80 | Rad54l | 3489 | 0.259 | 0.4887 | Yes |
| 81 | Nek2 | 3570 | 0.254 | 0.4898 | Yes |
| 82 | Odf2 | 3599 | 0.252 | 0.4936 | Yes |
| 83 | Smarcc1 | 3621 | 0.251 | 0.4977 | Yes |
| 84 | Srsf10 | 3746 | 0.244 | 0.4964 | Yes |
| 85 | Abl1 | 3805 | 0.240 | 0.4983 | Yes |
| 86 | Rpa2 | 3830 | 0.238 | 0.5020 | Yes |
| 87 | Tmpo | 3929 | 0.232 | 0.5018 | Yes |
| 88 | Snrpd1 | 3966 | 0.230 | 0.5047 | Yes |
| 89 | Slc38a1 | 3971 | 0.229 | 0.5092 | Yes |
| 90 | Smc4 | 4126 | 0.222 | 0.5059 | Yes |
| 91 | Chek1 | 4158 | 0.221 | 0.5088 | Yes |
| 92 | Ube2s | 4249 | 0.217 | 0.5087 | Yes |
| 93 | Plk1 | 4294 | 0.214 | 0.5109 | Yes |
| 94 | Ss18 | 4379 | 0.208 | 0.5109 | Yes |
| 95 | Polq | 4480 | 0.202 | 0.5099 | Yes |
| 96 | Syncrip | 4571 | 0.198 | 0.5094 | Yes |
| 97 | Gspt1 | 4647 | 0.195 | 0.5096 | Yes |
| 98 | Prpf4b | 4759 | 0.189 | 0.5078 | Yes |
| 99 | Tra2b | 4828 | 0.186 | 0.5082 | Yes |
| 100 | Tnpo2 | 4833 | 0.186 | 0.5118 | Yes |
| 101 | Ythdc1 | 4847 | 0.185 | 0.5149 | Yes |
| 102 | Pafah1b1 | 4889 | 0.184 | 0.5166 | Yes |
| 103 | Mcm6 | 5005 | 0.178 | 0.5144 | Yes |
| 104 | Ezh2 | 5034 | 0.177 | 0.5166 | Yes |
| 105 | Mcm5 | 5043 | 0.177 | 0.5199 | Yes |
| 106 | Slc7a1 | 5050 | 0.176 | 0.5232 | Yes |
| 107 | Knl1 | 5084 | 0.174 | 0.5251 | Yes |
| 108 | Kif2c | 5193 | 0.169 | 0.5230 | No |
| 109 | Orc6 | 5281 | 0.165 | 0.5220 | No |
| 110 | Hmga1b | 5310 | 0.163 | 0.5239 | No |
| 111 | Pole | 5535 | 0.151 | 0.5156 | No |
| 112 | Suv39h1 | 5623 | 0.147 | 0.5142 | No |
| 113 | E2f2 | 5743 | 0.143 | 0.5110 | No |
| 114 | Rbl1 | 5865 | 0.139 | 0.5077 | No |
| 115 | Kif23 | 5927 | 0.137 | 0.5074 | No |
| 116 | Cul5 | 6080 | 0.130 | 0.5023 | No |
| 117 | Kif5b | 6302 | 0.120 | 0.4935 | No |
| 118 | Stil | 6351 | 0.118 | 0.4935 | No |
| 119 | Cdc27 | 6417 | 0.115 | 0.4925 | No |
| 120 | Prim2 | 6440 | 0.114 | 0.4938 | No |
| 121 | Ctcf | 6519 | 0.111 | 0.4920 | No |
| 122 | Meis1 | 6549 | 0.109 | 0.4928 | No |
| 123 | Exo1 | 6606 | 0.107 | 0.4921 | No |
| 124 | Hus1 | 6685 | 0.104 | 0.4903 | No |
| 125 | Notch2 | 6809 | 0.100 | 0.4861 | No |
| 126 | Jpt1 | 6827 | 0.099 | 0.4872 | No |
| 127 | Pola2 | 6938 | 0.094 | 0.4836 | No |
| 128 | Ccnb2 | 6957 | 0.093 | 0.4846 | No |
| 129 | Pds5b | 6960 | 0.093 | 0.4864 | No |
| 130 | Slc7a5 | 6973 | 0.092 | 0.4877 | No |
| 131 | Arid4a | 6989 | 0.092 | 0.4888 | No |
| 132 | Nusap1 | 7229 | 0.081 | 0.4782 | No |
| 133 | Smad3 | 7234 | 0.081 | 0.4797 | No |
| 134 | Mtf2 | 7248 | 0.080 | 0.4807 | No |
| 135 | Cks1b | 7259 | 0.079 | 0.4818 | No |
| 136 | Troap | 7275 | 0.078 | 0.4826 | No |
| 137 | Cbx1 | 7313 | 0.077 | 0.4823 | No |
| 138 | Hira | 7430 | 0.071 | 0.4779 | No |
| 139 | Pttg1 | 7443 | 0.071 | 0.4787 | No |
| 140 | Bard1 | 7567 | 0.066 | 0.4738 | No |
| 141 | Cks2 | 7636 | 0.063 | 0.4716 | No |
| 142 | Stag1 | 7865 | 0.054 | 0.4611 | No |
| 143 | Dkc1 | 7933 | 0.051 | 0.4587 | No |
| 144 | Casp8ap2 | 8330 | 0.034 | 0.4392 | No |
| 145 | Cul3 | 8446 | 0.030 | 0.4339 | No |
| 146 | Tle3 | 8527 | 0.026 | 0.4304 | No |
| 147 | Atrx | 8587 | 0.024 | 0.4279 | No |
| 148 | Mapk14 | 8603 | 0.023 | 0.4276 | No |
| 149 | Cul4a | 8770 | 0.016 | 0.4195 | No |
| 150 | Dtymk | 8776 | 0.016 | 0.4195 | No |
| 151 | Mnat1 | 8887 | 0.012 | 0.4142 | No |
| 152 | Ewsr1 | 8959 | 0.009 | 0.4107 | No |
| 153 | Cdc45 | 8986 | 0.008 | 0.4096 | No |
| 154 | Ube2c | 8993 | 0.008 | 0.4094 | No |
| 155 | Cdc20 | 8994 | 0.008 | 0.4096 | No |
| 156 | Brca2 | 9473 | -0.006 | 0.3853 | No |
| 157 | Pura | 9603 | -0.011 | 0.3789 | No |
| 158 | Sqle | 9828 | -0.019 | 0.3679 | No |
| 159 | Tent4a | 9931 | -0.024 | 0.3632 | No |
| 160 | Kmt5a | 10015 | -0.028 | 0.3595 | No |
| 161 | Cdk4 | 10287 | -0.039 | 0.3465 | No |
| 162 | Wrn | 10419 | -0.044 | 0.3407 | No |
| 163 | Ddx39a | 10527 | -0.048 | 0.3362 | No |
| 164 | Gins2 | 10602 | -0.050 | 0.3334 | No |
| 165 | H2ax | 10766 | -0.058 | 0.3263 | No |
| 166 | Slc12a2 | 11019 | -0.069 | 0.3149 | No |
| 167 | Orc5 | 11160 | -0.076 | 0.3093 | No |
| 168 | Srsf2 | 11469 | -0.088 | 0.2954 | No |
| 169 | Nup98 | 11522 | -0.090 | 0.2946 | No |
| 170 | Bub3 | 12446 | -0.128 | 0.2500 | No |
| 171 | Meis2 | 12465 | -0.128 | 0.2518 | No |
| 172 | Katna1 | 12591 | -0.133 | 0.2481 | No |
| 173 | Fancc | 12634 | -0.134 | 0.2487 | No |
| 174 | Rps6ka5 | 12710 | -0.137 | 0.2477 | No |
| 175 | Hmgb3 | 12719 | -0.137 | 0.2501 | No |
| 176 | Map3k20 | 12838 | -0.141 | 0.2470 | No |
| 177 | E2f1 | 12872 | -0.143 | 0.2483 | No |
| 178 | H2az2 | 12948 | -0.146 | 0.2474 | No |
| 179 | Cenpa | 13183 | -0.156 | 0.2387 | No |
| 180 | Traip | 13330 | -0.163 | 0.2346 | No |
| 181 | Hif1a | 13552 | -0.173 | 0.2269 | No |
| 182 | Cdkn3 | 13940 | -0.188 | 0.2110 | No |
| 183 | Pml | 14154 | -0.200 | 0.2042 | No |
| 184 | Rasal2 | 14594 | -0.221 | 0.1863 | No |
| 185 | Dmd | 14755 | -0.229 | 0.1829 | No |
| 186 | Foxn3 | 14836 | -0.234 | 0.1836 | No |
| 187 | Myc | 15501 | -0.268 | 0.1552 | No |
| 188 | Efna5 | 16203 | -0.308 | 0.1257 | No |
| 189 | Stmn1 | 16569 | -0.331 | 0.1139 | No |
| 190 | Tgfb1 | 16886 | -0.350 | 0.1050 | No |
| 191 | Egf | 17333 | -0.384 | 0.0901 | No |
| 192 | Chmp1a | 17671 | -0.412 | 0.0814 | No |
| 193 | Marcks | 18252 | -0.474 | 0.0615 | No |
| 194 | Ccnd1 | 19518 | -0.779 | 0.0129 | No |

