| Dataset | CMP.CMP_Pheno.cls#Group2_versus_Group3.CMP_Pheno.cls#Group2_versus_Group3_repos |
| Phenotype | CMP_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.539253 |
| Normalized Enrichment Score (NES) | 1.7689223 |
| Nominal p-value | 0.036190476 |
| FDR q-value | 0.05348412 |
| FWER p-Value | 0.076 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Srsf1 | 90 | 0.786 | 0.0118 | Yes |
| 2 | Dck | 195 | 0.709 | 0.0212 | Yes |
| 3 | Brca1 | 217 | 0.696 | 0.0346 | Yes |
| 4 | Anp32e | 261 | 0.664 | 0.0462 | Yes |
| 5 | Tfrc | 267 | 0.662 | 0.0598 | Yes |
| 6 | Bub1b | 279 | 0.656 | 0.0729 | Yes |
| 7 | Dnmt1 | 366 | 0.620 | 0.0814 | Yes |
| 8 | Lbr | 415 | 0.598 | 0.0914 | Yes |
| 9 | Ipo7 | 417 | 0.598 | 0.1038 | Yes |
| 10 | Espl1 | 489 | 0.577 | 0.1121 | Yes |
| 11 | Cse1l | 491 | 0.575 | 0.1241 | Yes |
| 12 | Ccne1 | 498 | 0.573 | 0.1357 | Yes |
| 13 | Smc1a | 505 | 0.571 | 0.1473 | Yes |
| 14 | Xpo1 | 646 | 0.537 | 0.1513 | Yes |
| 15 | Lmnb1 | 649 | 0.537 | 0.1624 | Yes |
| 16 | Melk | 676 | 0.530 | 0.1721 | Yes |
| 17 | Cdca8 | 708 | 0.525 | 0.1814 | Yes |
| 18 | Hnrnpd | 713 | 0.524 | 0.1921 | Yes |
| 19 | Rrm2 | 715 | 0.524 | 0.2030 | Yes |
| 20 | Nup107 | 775 | 0.511 | 0.2106 | Yes |
| 21 | Ncapd2 | 777 | 0.511 | 0.2212 | Yes |
| 22 | Aurkb | 866 | 0.492 | 0.2270 | Yes |
| 23 | Kif4 | 935 | 0.482 | 0.2335 | Yes |
| 24 | Rbbp7 | 944 | 0.480 | 0.2431 | Yes |
| 25 | Ssrp1 | 954 | 0.479 | 0.2526 | Yes |
| 26 | Smc3 | 1064 | 0.464 | 0.2567 | Yes |
| 27 | Nasp | 1088 | 0.460 | 0.2651 | Yes |
| 28 | Top2a | 1162 | 0.450 | 0.2708 | Yes |
| 29 | Slbp | 1195 | 0.447 | 0.2784 | Yes |
| 30 | Prps1 | 1282 | 0.437 | 0.2831 | Yes |
| 31 | Cdk1 | 1292 | 0.434 | 0.2917 | Yes |
| 32 | Asf1b | 1487 | 0.411 | 0.2903 | Yes |
| 33 | Rad51ap1 | 1519 | 0.407 | 0.2972 | Yes |
| 34 | H2az1 | 1588 | 0.398 | 0.3020 | Yes |
| 35 | Hmmr | 1597 | 0.396 | 0.3099 | Yes |
| 36 | Tacc3 | 1636 | 0.392 | 0.3161 | Yes |
| 37 | Nolc1 | 1642 | 0.391 | 0.3240 | Yes |
| 38 | Aurka | 1692 | 0.386 | 0.3295 | Yes |
| 39 | Racgap1 | 1694 | 0.386 | 0.3375 | Yes |
| 40 | Birc5 | 1784 | 0.378 | 0.3408 | Yes |
| 41 | Mybl2 | 1787 | 0.377 | 0.3486 | Yes |
| 42 | Mki67 | 1869 | 0.369 | 0.3521 | Yes |
| 43 | Cdc25a | 1870 | 0.368 | 0.3598 | Yes |
| 44 | Rad21 | 1901 | 0.367 | 0.3659 | Yes |
| 45 | Cbx5 | 1945 | 0.363 | 0.3712 | Yes |
| 46 | Mcm7 | 2025 | 0.356 | 0.3746 | Yes |
| 47 | Brms1l | 2033 | 0.356 | 0.3817 | Yes |
| 48 | Pa2g4 | 2057 | 0.354 | 0.3879 | Yes |
| 49 | Atad2 | 2074 | 0.352 | 0.3944 | Yes |
| 50 | Ccp110 | 2084 | 0.351 | 0.4012 | Yes |
| 51 | Nap1l1 | 2109 | 0.350 | 0.4073 | Yes |
| 52 | Lig1 | 2136 | 0.348 | 0.4132 | Yes |
| 53 | Cdkn1b | 2204 | 0.343 | 0.4169 | Yes |
| 54 | Mcm4 | 2342 | 0.333 | 0.4169 | Yes |
| 55 | Ubr7 | 2350 | 0.332 | 0.4234 | Yes |
| 56 | Ilf3 | 2371 | 0.331 | 0.4293 | Yes |
| 57 | Mad2l1 | 2391 | 0.329 | 0.4352 | Yes |
| 58 | Cit | 2453 | 0.325 | 0.4388 | Yes |
| 59 | Mcm3 | 2643 | 0.312 | 0.4357 | Yes |
| 60 | Mcm2 | 2674 | 0.310 | 0.4406 | Yes |
| 61 | Tbrg4 | 2741 | 0.305 | 0.4435 | Yes |
| 62 | Phf5a | 2893 | 0.295 | 0.4420 | Yes |
| 63 | Plk4 | 2929 | 0.293 | 0.4463 | Yes |
| 64 | Psip1 | 2946 | 0.292 | 0.4515 | Yes |
| 65 | Cenpe | 2966 | 0.290 | 0.4566 | Yes |
| 66 | Cdkn2c | 2977 | 0.289 | 0.4621 | Yes |
| 67 | Kif22 | 3010 | 0.287 | 0.4665 | Yes |
| 68 | Cdc25b | 3084 | 0.282 | 0.4686 | Yes |
| 69 | Nup205 | 3107 | 0.281 | 0.4733 | Yes |
| 70 | Dlgap5 | 3121 | 0.280 | 0.4785 | Yes |
| 71 | Ranbp1 | 3365 | 0.265 | 0.4716 | Yes |
| 72 | Pnn | 3368 | 0.265 | 0.4770 | Yes |
| 73 | Msh2 | 3430 | 0.262 | 0.4794 | Yes |
| 74 | Cnot9 | 3573 | 0.254 | 0.4774 | Yes |
| 75 | Rpa1 | 3592 | 0.253 | 0.4817 | Yes |
| 76 | Lsm8 | 3618 | 0.251 | 0.4857 | Yes |
| 77 | Trip13 | 3640 | 0.250 | 0.4898 | Yes |
| 78 | Smc6 | 3698 | 0.247 | 0.4920 | Yes |
| 79 | Hells | 3751 | 0.244 | 0.4945 | Yes |
| 80 | Rpa2 | 3830 | 0.238 | 0.4954 | Yes |
| 81 | E2f8 | 3879 | 0.234 | 0.4979 | Yes |
| 82 | Tmpo | 3929 | 0.232 | 0.5002 | Yes |
| 83 | Paics | 3984 | 0.229 | 0.5022 | Yes |
| 84 | Eif2s1 | 3986 | 0.229 | 0.5069 | Yes |
| 85 | Smc4 | 4126 | 0.222 | 0.5044 | Yes |
| 86 | Chek1 | 4158 | 0.221 | 0.5074 | Yes |
| 87 | Ube2s | 4249 | 0.217 | 0.5073 | Yes |
| 88 | Plk1 | 4294 | 0.214 | 0.5095 | Yes |
| 89 | Nup153 | 4388 | 0.208 | 0.5091 | Yes |
| 90 | Ran | 4440 | 0.205 | 0.5108 | Yes |
| 91 | Rad1 | 4540 | 0.199 | 0.5098 | Yes |
| 92 | Mre11a | 4569 | 0.198 | 0.5125 | Yes |
| 93 | Syncrip | 4571 | 0.198 | 0.5166 | Yes |
| 94 | Prkdc | 4578 | 0.198 | 0.5204 | Yes |
| 95 | Spc25 | 4625 | 0.196 | 0.5221 | Yes |
| 96 | Gspt1 | 4647 | 0.195 | 0.5251 | Yes |
| 97 | Rnaseh2a | 4691 | 0.192 | 0.5269 | Yes |
| 98 | Usp1 | 4711 | 0.191 | 0.5299 | Yes |
| 99 | Tubb5 | 4755 | 0.189 | 0.5317 | Yes |
| 100 | Tra2b | 4828 | 0.186 | 0.5319 | Yes |
| 101 | Mcm6 | 5005 | 0.178 | 0.5266 | Yes |
| 102 | Ezh2 | 5034 | 0.177 | 0.5288 | Yes |
| 103 | Mcm5 | 5043 | 0.177 | 0.5321 | Yes |
| 104 | Orc2 | 5152 | 0.171 | 0.5301 | Yes |
| 105 | Kif2c | 5193 | 0.169 | 0.5316 | Yes |
| 106 | Orc6 | 5281 | 0.165 | 0.5306 | Yes |
| 107 | Hmga1b | 5310 | 0.163 | 0.5326 | Yes |
| 108 | Rfc1 | 5329 | 0.162 | 0.5350 | Yes |
| 109 | Spag5 | 5340 | 0.161 | 0.5379 | Yes |
| 110 | Mthfd2 | 5379 | 0.160 | 0.5393 | Yes |
| 111 | Pole | 5535 | 0.151 | 0.5345 | No |
| 112 | Tipin | 5622 | 0.147 | 0.5332 | No |
| 113 | Suv39h1 | 5623 | 0.147 | 0.5362 | No |
| 114 | Nudt21 | 5698 | 0.144 | 0.5354 | No |
| 115 | Rpa3 | 5759 | 0.142 | 0.5353 | No |
| 116 | Cdkn2a | 5867 | 0.139 | 0.5328 | No |
| 117 | Nop56 | 6114 | 0.128 | 0.5229 | No |
| 118 | Lyar | 6172 | 0.125 | 0.5226 | No |
| 119 | Timeless | 6185 | 0.125 | 0.5245 | No |
| 120 | Rad50 | 6301 | 0.120 | 0.5212 | No |
| 121 | Pold3 | 6346 | 0.118 | 0.5214 | No |
| 122 | Ppm1d | 6349 | 0.118 | 0.5237 | No |
| 123 | Tcf19 | 6393 | 0.116 | 0.5240 | No |
| 124 | Prim2 | 6440 | 0.114 | 0.5240 | No |
| 125 | Ctcf | 6519 | 0.111 | 0.5223 | No |
| 126 | Pole4 | 6599 | 0.107 | 0.5205 | No |
| 127 | Ube2t | 6660 | 0.105 | 0.5196 | No |
| 128 | Hus1 | 6685 | 0.104 | 0.5205 | No |
| 129 | Jpt1 | 6827 | 0.099 | 0.5154 | No |
| 130 | Zw10 | 6919 | 0.095 | 0.5127 | No |
| 131 | Pola2 | 6938 | 0.094 | 0.5138 | No |
| 132 | Ccnb2 | 6957 | 0.093 | 0.5148 | No |
| 133 | Pds5b | 6960 | 0.093 | 0.5166 | No |
| 134 | Cdkn1a | 6987 | 0.092 | 0.5172 | No |
| 135 | Asf1a | 7097 | 0.086 | 0.5134 | No |
| 136 | Gins1 | 7154 | 0.084 | 0.5123 | No |
| 137 | Gins3 | 7211 | 0.082 | 0.5112 | No |
| 138 | Exosc8 | 7212 | 0.082 | 0.5129 | No |
| 139 | Cks1b | 7259 | 0.079 | 0.5122 | No |
| 140 | Hmgb2 | 7260 | 0.079 | 0.5138 | No |
| 141 | Tk1 | 7320 | 0.077 | 0.5124 | No |
| 142 | Dut | 7353 | 0.075 | 0.5123 | No |
| 143 | Dek | 7424 | 0.072 | 0.5102 | No |
| 144 | Pttg1 | 7443 | 0.071 | 0.5108 | No |
| 145 | Mms22l | 7456 | 0.070 | 0.5116 | No |
| 146 | Bard1 | 7567 | 0.066 | 0.5074 | No |
| 147 | Kif18b | 7571 | 0.066 | 0.5086 | No |
| 148 | Cks2 | 7636 | 0.063 | 0.5067 | No |
| 149 | Mlh1 | 7683 | 0.061 | 0.5056 | No |
| 150 | Diaph3 | 7752 | 0.059 | 0.5033 | No |
| 151 | Stag1 | 7865 | 0.054 | 0.4987 | No |
| 152 | Rad51c | 8127 | 0.043 | 0.4863 | No |
| 153 | Luc7l3 | 8276 | 0.037 | 0.4795 | No |
| 154 | Wee1 | 8707 | 0.019 | 0.4579 | No |
| 155 | Shmt1 | 8763 | 0.017 | 0.4555 | No |
| 156 | Donson | 8958 | 0.009 | 0.4457 | No |
| 157 | Cdc20 | 8994 | 0.008 | 0.4441 | No |
| 158 | Chek2 | 9104 | 0.004 | 0.4386 | No |
| 159 | Ppp1r8 | 9298 | -0.000 | 0.4288 | No |
| 160 | Dctpp1 | 9343 | -0.002 | 0.4266 | No |
| 161 | Psmc3ip | 9446 | -0.005 | 0.4215 | No |
| 162 | Brca2 | 9473 | -0.006 | 0.4202 | No |
| 163 | Eed | 9543 | -0.009 | 0.4169 | No |
| 164 | Mxd3 | 9620 | -0.012 | 0.4133 | No |
| 165 | Depdc1a | 9722 | -0.015 | 0.4084 | No |
| 166 | Pop7 | 9909 | -0.023 | 0.3994 | No |
| 167 | Ak2 | 9954 | -0.025 | 0.3977 | No |
| 168 | Nbn | 10060 | -0.030 | 0.3929 | No |
| 169 | Trp53 | 10188 | -0.035 | 0.3872 | No |
| 170 | Xrcc6 | 10230 | -0.036 | 0.3858 | No |
| 171 | Pcna | 10243 | -0.037 | 0.3860 | No |
| 172 | Cdk4 | 10287 | -0.039 | 0.3846 | No |
| 173 | Ddx39a | 10527 | -0.048 | 0.3734 | No |
| 174 | Nme1 | 10640 | -0.053 | 0.3688 | No |
| 175 | H2ax | 10766 | -0.058 | 0.3636 | No |
| 176 | Tubg1 | 11022 | -0.069 | 0.3520 | No |
| 177 | Spc24 | 11145 | -0.075 | 0.3473 | No |
| 178 | Srsf2 | 11469 | -0.088 | 0.3327 | No |
| 179 | Rfc3 | 11887 | -0.105 | 0.3135 | No |
| 180 | Prdx4 | 12137 | -0.115 | 0.3032 | No |
| 181 | Pold2 | 12255 | -0.120 | 0.2997 | No |
| 182 | Ung | 12363 | -0.125 | 0.2969 | No |
| 183 | Hmgb3 | 12719 | -0.137 | 0.2816 | No |
| 184 | Pms2 | 12957 | -0.146 | 0.2725 | No |
| 185 | Ing3 | 13724 | -0.180 | 0.2371 | No |
| 186 | Cdkn3 | 13940 | -0.188 | 0.2301 | No |
| 187 | Rfc2 | 14115 | -0.198 | 0.2253 | No |
| 188 | Cdca3 | 14406 | -0.211 | 0.2149 | No |
| 189 | Pan2 | 14437 | -0.213 | 0.2178 | No |
| 190 | Gins4 | 14490 | -0.215 | 0.2196 | No |
| 191 | Wdr90 | 15043 | -0.243 | 0.1965 | No |
| 192 | Pold1 | 15161 | -0.250 | 0.1957 | No |
| 193 | Myc | 15501 | -0.268 | 0.1839 | No |
| 194 | Snrpb | 15580 | -0.271 | 0.1856 | No |
| 195 | Dclre1b | 16148 | -0.304 | 0.1630 | No |
| 196 | Stmn1 | 16569 | -0.331 | 0.1484 | No |
| 197 | Dscc1 | 17005 | -0.358 | 0.1336 | No |
| 198 | Cenpm | 17127 | -0.367 | 0.1351 | No |

