Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	CMP.CMP_Pheno.cls#Group1_versus_Group4.CMP_Pheno.cls#Group1_versus_Group4_repos
Phenotype	CMP_Pheno.cls#Group1_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.24308288
Normalized Enrichment Score (NES)	-1.1712183
Nominal p-value	0.26003823
FDR q-value	0.4113022
FWER p-Value	0.893

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Ptpn11	1316	0.444	-0.0456	No
2	Map2k3	1641	0.408	-0.0425	No
3	Ube2n	1833	0.389	-0.0336	No
4	Plcg1	2289	0.352	-0.0399	No
5	Akt1	2443	0.339	-0.0314	No
6	Mapk10	2734	0.318	-0.0309	No
7	Dusp3	3272	0.286	-0.0445	No
8	Pikfyve	3398	0.277	-0.0376	No
9	Cltc	3400	0.276	-0.0244	No
10	Pak4	3418	0.275	-0.0121	No
11	Ppp2r1b	3430	0.274	0.0004	No
12	Actr2	3523	0.266	0.0085	No
13	Calr	3915	0.244	0.0004	No
14	Sfn	4056	0.237	0.0046	No
15	Cab39	4112	0.234	0.0130	No
16	Map3k7	4268	0.226	0.0160	No
17	Prkaa2	4362	0.221	0.0218	No
18	Atf1	4483	0.215	0.0260	No
19	Pin1	4782	0.199	0.0204	No
20	Gsk3b	4896	0.192	0.0239	No
21	Cdkn1a	5106	0.180	0.0219	No
22	Gna14	5302	0.173	0.0203	No
23	Mapk9	5425	0.168	0.0221	No
24	Pdk1	5565	0.162	0.0228	No
25	Stat2	5715	0.154	0.0226	No
26	Hsp90b1	5850	0.148	0.0229	No
27	Mapk8	5856	0.148	0.0297	No
28	Prkar2a	5864	0.147	0.0365	No
29	Raf1	5955	0.143	0.0387	No
30	Arf1	6325	0.127	0.0261	No
31	Pten	6552	0.117	0.0202	No
32	Ube2d3	6565	0.116	0.0251	No
33	Egfr	6620	0.114	0.0278	No
34	Myd88	6739	0.113	0.0273	No
35	Grb2	6953	0.104	0.0214	No
36	Smad2	7127	0.097	0.0173	No
37	Rptor	7269	0.091	0.0144	No
38	Traf2	7519	0.081	0.0056	No
39	Mapkap1	7948	0.062	-0.0131	No
40	Pla2g12a	8561	0.038	-0.0424	No
41	Tsc2	8721	0.031	-0.0490	No
42	Rit1	8813	0.027	-0.0523	No
43	Actr3	8899	0.024	-0.0555	No
44	Mapk1	8957	0.022	-0.0573	No
45	Plcb1	9360	0.006	-0.0775	No
46	Eif4e	9411	0.004	-0.0798	No
47	Adcy2	9697	-0.003	-0.0942	No
48	Vav3	9764	-0.005	-0.0973	No
49	Rps6ka3	9828	-0.009	-0.1001	No
50	Tbk1	10024	-0.015	-0.1092	No
51	Tiam1	10226	-0.023	-0.1184	No
52	Map2k6	10305	-0.026	-0.1211	No
53	Grk2	10592	-0.038	-0.1338	No
54	Mknk2	10611	-0.038	-0.1329	No
55	Mknk1	10777	-0.045	-0.1391	No
56	Cab39l	11298	-0.066	-0.1624	No
57	Pik3r3	11346	-0.068	-0.1615	No
58	E2f1	11628	-0.081	-0.1719	No
59	Cdkn1b	11654	-0.082	-0.1692	No
60	Sqstm1	11773	-0.086	-0.1711	No
61	Ywhab	11919	-0.093	-0.1740	No
62	Itpr2	11932	-0.094	-0.1701	No
63	Akt1s1	12096	-0.100	-0.1736	No
64	Prkcb	12237	-0.107	-0.1756	No
65	Rps6ka1	12264	-0.108	-0.1718	No
66	Pitx2	12690	-0.127	-0.1873	No
67	Cdk1	12998	-0.137	-0.1964	No
68	Arpc3	13918	-0.173	-0.2348	Yes
69	Arhgdia	13980	-0.176	-0.2294	Yes
70	Slc2a1	14034	-0.179	-0.2236	Yes
71	Dapp1	14073	-0.181	-0.2168	Yes
72	Nck1	14132	-0.184	-0.2109	Yes
73	Ap2m1	14513	-0.205	-0.2204	Yes
74	Ppp1ca	14564	-0.208	-0.2130	Yes
75	Ripk1	14625	-0.210	-0.2060	Yes
76	Lck	15093	-0.236	-0.2184	Yes
77	Irak4	15096	-0.236	-0.2072	Yes
78	Il2rg	15532	-0.259	-0.2169	Yes
79	Acaca	15571	-0.261	-0.2063	Yes
80	Trib3	15622	-0.265	-0.1962	Yes
81	Cdk2	15765	-0.270	-0.1905	Yes
82	Them4	15797	-0.272	-0.1790	Yes
83	Rac1	15809	-0.273	-0.1665	Yes
84	Cxcr4	15890	-0.277	-0.1573	Yes
85	Sla	16189	-0.295	-0.1583	Yes
86	Prkag1	16250	-0.299	-0.1471	Yes
87	Hras	16259	-0.300	-0.1331	Yes
88	Pfn1	16266	-0.300	-0.1190	Yes
89	Cdk4	17024	-0.347	-0.1409	Yes
90	Nfkbib	17779	-0.409	-0.1596	Yes
91	Tnfrsf1a	18109	-0.440	-0.1552	Yes
92	Camk4	18282	-0.460	-0.1419	Yes
93	Ddit3	18645	-0.507	-0.1360	Yes
94	Ecsit	18790	-0.530	-0.1179	Yes
95	Ralb	19014	-0.576	-0.1017	Yes
96	Cfl1	19209	-0.625	-0.0816	Yes
97	Csnk2b	19257	-0.638	-0.0534	Yes
98	Nod1	19618	-0.815	-0.0327	Yes
99	Il4	19644	-0.844	0.0065	Yes