| Dataset | CMP.CMP_Pheno.cls#Group1_versus_Group4.CMP_Pheno.cls#Group1_versus_Group4_repos |
| Phenotype | CMP_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.33523455 |
| Normalized Enrichment Score (NES) | 1.4857553 |
| Nominal p-value | 0.14455445 |
| FDR q-value | 0.1938191 |
| FWER p-Value | 0.411 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Odc1 | 121 | 0.778 | 0.0133 | Yes |
| 2 | Sqle | 249 | 0.676 | 0.0237 | Yes |
| 3 | Hnrnpd | 251 | 0.676 | 0.0406 | Yes |
| 4 | Racgap1 | 265 | 0.666 | 0.0566 | Yes |
| 5 | Kpnb1 | 426 | 0.608 | 0.0636 | Yes |
| 6 | Amd1 | 555 | 0.566 | 0.0712 | Yes |
| 7 | Mcm2 | 655 | 0.545 | 0.0798 | Yes |
| 8 | Hnrnpu | 669 | 0.543 | 0.0927 | Yes |
| 9 | Numa1 | 727 | 0.530 | 0.1031 | Yes |
| 10 | Upf1 | 793 | 0.517 | 0.1127 | Yes |
| 11 | Hspa8 | 809 | 0.514 | 0.1248 | Yes |
| 12 | Mcm5 | 930 | 0.497 | 0.1311 | Yes |
| 13 | Ccnd1 | 946 | 0.494 | 0.1427 | Yes |
| 14 | Incenp | 1065 | 0.477 | 0.1486 | Yes |
| 15 | Srsf1 | 1121 | 0.468 | 0.1575 | Yes |
| 16 | Sfpq | 1132 | 0.467 | 0.1686 | Yes |
| 17 | Uck2 | 1142 | 0.465 | 0.1798 | Yes |
| 18 | Chaf1a | 1221 | 0.454 | 0.1872 | Yes |
| 19 | Espl1 | 1336 | 0.441 | 0.1924 | Yes |
| 20 | Ewsr1 | 1341 | 0.440 | 0.2032 | Yes |
| 21 | Xpo1 | 1378 | 0.435 | 0.2123 | Yes |
| 22 | Tfdp1 | 1402 | 0.433 | 0.2219 | Yes |
| 23 | Pole | 1404 | 0.433 | 0.2327 | Yes |
| 24 | Lmnb1 | 1512 | 0.422 | 0.2378 | Yes |
| 25 | H2bc12 | 1738 | 0.398 | 0.2363 | Yes |
| 26 | Rad21 | 1822 | 0.390 | 0.2418 | Yes |
| 27 | Kif2c | 2234 | 0.357 | 0.2297 | Yes |
| 28 | Cks2 | 2242 | 0.356 | 0.2383 | Yes |
| 29 | Smc1a | 2558 | 0.331 | 0.2305 | Yes |
| 30 | Mcm6 | 2786 | 0.316 | 0.2268 | Yes |
| 31 | Lbr | 3045 | 0.300 | 0.2211 | Yes |
| 32 | G3bp1 | 3242 | 0.287 | 0.2183 | Yes |
| 33 | Ss18 | 3367 | 0.279 | 0.2189 | Yes |
| 34 | Gspt1 | 3374 | 0.279 | 0.2256 | Yes |
| 35 | Atf5 | 3493 | 0.269 | 0.2263 | Yes |
| 36 | Tra2b | 3506 | 0.268 | 0.2324 | Yes |
| 37 | Notch2 | 3636 | 0.260 | 0.2323 | Yes |
| 38 | Kif11 | 3680 | 0.258 | 0.2366 | Yes |
| 39 | Smarcc1 | 3695 | 0.257 | 0.2423 | Yes |
| 40 | Chek1 | 3765 | 0.255 | 0.2452 | Yes |
| 41 | Hif1a | 3775 | 0.254 | 0.2511 | Yes |
| 42 | Slc7a1 | 3862 | 0.248 | 0.2529 | Yes |
| 43 | Rad23b | 3960 | 0.242 | 0.2540 | Yes |
| 44 | Syncrip | 3966 | 0.241 | 0.2597 | Yes |
| 45 | Nolc1 | 3976 | 0.241 | 0.2653 | Yes |
| 46 | Abl1 | 3977 | 0.241 | 0.2713 | Yes |
| 47 | Cul3 | 4034 | 0.239 | 0.2744 | Yes |
| 48 | Mcm3 | 4038 | 0.238 | 0.2802 | Yes |
| 49 | Kif23 | 4258 | 0.226 | 0.2747 | Yes |
| 50 | Tent4a | 4276 | 0.226 | 0.2795 | Yes |
| 51 | Nup98 | 4315 | 0.224 | 0.2832 | Yes |
| 52 | Mapk14 | 4339 | 0.222 | 0.2875 | Yes |
| 53 | Cul1 | 4344 | 0.222 | 0.2929 | Yes |
| 54 | Pola2 | 4430 | 0.218 | 0.2940 | Yes |
| 55 | Rbl1 | 4444 | 0.217 | 0.2988 | Yes |
| 56 | Pds5b | 4607 | 0.208 | 0.2957 | Yes |
| 57 | Meis2 | 4618 | 0.207 | 0.3004 | Yes |
| 58 | Ilf3 | 4680 | 0.204 | 0.3024 | Yes |
| 59 | Dtymk | 4715 | 0.202 | 0.3057 | Yes |
| 60 | Ncl | 4874 | 0.193 | 0.3025 | Yes |
| 61 | Dkc1 | 4887 | 0.193 | 0.3067 | Yes |
| 62 | Prc1 | 4922 | 0.190 | 0.3097 | Yes |
| 63 | Odf2 | 5063 | 0.182 | 0.3071 | Yes |
| 64 | Nup50 | 5076 | 0.182 | 0.3111 | Yes |
| 65 | Orc6 | 5238 | 0.177 | 0.3073 | Yes |
| 66 | Suv39h1 | 5273 | 0.175 | 0.3099 | Yes |
| 67 | Ccnt1 | 5277 | 0.174 | 0.3141 | Yes |
| 68 | H2az1 | 5301 | 0.173 | 0.3173 | Yes |
| 69 | Pafah1b1 | 5334 | 0.172 | 0.3199 | Yes |
| 70 | Top2a | 5376 | 0.170 | 0.3221 | Yes |
| 71 | Aurka | 5384 | 0.170 | 0.3260 | Yes |
| 72 | Rasal2 | 5461 | 0.167 | 0.3263 | Yes |
| 73 | Mtf2 | 5535 | 0.164 | 0.3266 | Yes |
| 74 | Nsd2 | 5604 | 0.160 | 0.3272 | Yes |
| 75 | Tmpo | 5705 | 0.155 | 0.3259 | Yes |
| 76 | Cdc25a | 5727 | 0.154 | 0.3287 | Yes |
| 77 | Bub1 | 5798 | 0.151 | 0.3289 | Yes |
| 78 | Cdc45 | 5880 | 0.146 | 0.3284 | Yes |
| 79 | Nasp | 5893 | 0.146 | 0.3314 | Yes |
| 80 | Exo1 | 5913 | 0.145 | 0.3341 | Yes |
| 81 | Srsf2 | 5962 | 0.143 | 0.3352 | Yes |
| 82 | Plk1 | 6051 | 0.139 | 0.3342 | No |
| 83 | Mki67 | 6145 | 0.135 | 0.3328 | No |
| 84 | Slc7a5 | 6239 | 0.132 | 0.3314 | No |
| 85 | Cdc25b | 6446 | 0.121 | 0.3239 | No |
| 86 | Prim2 | 7183 | 0.094 | 0.2887 | No |
| 87 | Mybl2 | 7235 | 0.092 | 0.2884 | No |
| 88 | Cenpe | 7288 | 0.090 | 0.2879 | No |
| 89 | Wrn | 7511 | 0.081 | 0.2786 | No |
| 90 | Orc5 | 7561 | 0.079 | 0.2781 | No |
| 91 | Egf | 7570 | 0.078 | 0.2796 | No |
| 92 | E2f3 | 7593 | 0.077 | 0.2805 | No |
| 93 | Slc12a2 | 7647 | 0.076 | 0.2796 | No |
| 94 | Aurkb | 7751 | 0.071 | 0.2761 | No |
| 95 | Stmn1 | 7806 | 0.068 | 0.2751 | No |
| 96 | Dr1 | 7822 | 0.067 | 0.2760 | No |
| 97 | Dbf4 | 7837 | 0.067 | 0.2770 | No |
| 98 | Srsf10 | 7956 | 0.062 | 0.2725 | No |
| 99 | Cul5 | 7976 | 0.061 | 0.2730 | No |
| 100 | Ube2s | 8050 | 0.058 | 0.2707 | No |
| 101 | Cul4a | 8145 | 0.053 | 0.2673 | No |
| 102 | Ddx39a | 8212 | 0.051 | 0.2652 | No |
| 103 | Ctcf | 8337 | 0.046 | 0.2600 | No |
| 104 | Cdc6 | 8488 | 0.041 | 0.2533 | No |
| 105 | Pbk | 8576 | 0.037 | 0.2498 | No |
| 106 | Map3k20 | 8635 | 0.035 | 0.2477 | No |
| 107 | Atrx | 8654 | 0.034 | 0.2476 | No |
| 108 | Bard1 | 8720 | 0.031 | 0.2451 | No |
| 109 | Tnpo2 | 8765 | 0.029 | 0.2436 | No |
| 110 | Slc38a1 | 8870 | 0.026 | 0.2389 | No |
| 111 | Cenpf | 8926 | 0.024 | 0.2367 | No |
| 112 | Fbxo5 | 8950 | 0.023 | 0.2361 | No |
| 113 | Ccnb2 | 9065 | 0.018 | 0.2307 | No |
| 114 | Smad3 | 9152 | 0.014 | 0.2267 | No |
| 115 | Ccnf | 9275 | 0.009 | 0.2207 | No |
| 116 | Ythdc1 | 9361 | 0.006 | 0.2165 | No |
| 117 | Fancc | 9376 | 0.005 | 0.2159 | No |
| 118 | Kif15 | 9406 | 0.004 | 0.2145 | No |
| 119 | Marcks | 9487 | 0.001 | 0.2105 | No |
| 120 | Foxn3 | 9959 | -0.013 | 0.1867 | No |
| 121 | Kif4 | 9964 | -0.013 | 0.1869 | No |
| 122 | Stag1 | 9972 | -0.014 | 0.1868 | No |
| 123 | Hus1 | 10086 | -0.017 | 0.1815 | No |
| 124 | Chmp1a | 10228 | -0.023 | 0.1749 | No |
| 125 | Arid4a | 10248 | -0.024 | 0.1745 | No |
| 126 | Ezh2 | 10284 | -0.025 | 0.1733 | No |
| 127 | Smc4 | 10336 | -0.027 | 0.1714 | No |
| 128 | Tle3 | 10514 | -0.034 | 0.1632 | No |
| 129 | Kif5b | 10529 | -0.035 | 0.1634 | No |
| 130 | Lig3 | 10589 | -0.038 | 0.1613 | No |
| 131 | Cdkn2c | 10600 | -0.038 | 0.1617 | No |
| 132 | Prpf4b | 10631 | -0.039 | 0.1612 | No |
| 133 | Hira | 10715 | -0.042 | 0.1580 | No |
| 134 | Rad54l | 10720 | -0.042 | 0.1589 | No |
| 135 | Nek2 | 10743 | -0.043 | 0.1588 | No |
| 136 | Bcl3 | 10792 | -0.045 | 0.1575 | No |
| 137 | Pml | 10935 | -0.051 | 0.1515 | No |
| 138 | Ccna2 | 10993 | -0.054 | 0.1500 | No |
| 139 | Top1 | 11068 | -0.057 | 0.1476 | No |
| 140 | Stil | 11073 | -0.057 | 0.1488 | No |
| 141 | Mad2l1 | 11173 | -0.061 | 0.1453 | No |
| 142 | Smc2 | 11242 | -0.064 | 0.1434 | No |
| 143 | Cdc7 | 11268 | -0.065 | 0.1438 | No |
| 144 | Casp8ap2 | 11333 | -0.068 | 0.1422 | No |
| 145 | Kif20b | 11340 | -0.068 | 0.1436 | No |
| 146 | Sap30 | 11399 | -0.071 | 0.1424 | No |
| 147 | Ndc80 | 11435 | -0.072 | 0.1425 | No |
| 148 | Ttk | 11498 | -0.075 | 0.1412 | No |
| 149 | Hmmr | 11613 | -0.080 | 0.1374 | No |
| 150 | E2f1 | 11628 | -0.081 | 0.1387 | No |
| 151 | Cdkn1b | 11654 | -0.082 | 0.1394 | No |
| 152 | Prmt5 | 11757 | -0.085 | 0.1364 | No |
| 153 | Plk4 | 12925 | -0.134 | 0.0801 | No |
| 154 | Cdk1 | 12998 | -0.137 | 0.0799 | No |
| 155 | Myc | 13024 | -0.139 | 0.0821 | No |
| 156 | Cdc27 | 13084 | -0.141 | 0.0826 | No |
| 157 | Knl1 | 13138 | -0.144 | 0.0835 | No |
| 158 | Cks1b | 13329 | -0.151 | 0.0775 | No |
| 159 | Cbx1 | 13423 | -0.155 | 0.0767 | No |
| 160 | Kmt5a | 13526 | -0.161 | 0.0755 | No |
| 161 | Meis1 | 13542 | -0.161 | 0.0788 | No |
| 162 | Nusap1 | 13555 | -0.162 | 0.0822 | No |
| 163 | Rps6ka5 | 13631 | -0.165 | 0.0825 | No |
| 164 | Tpx2 | 13718 | -0.169 | 0.0823 | No |
| 165 | Katna1 | 13814 | -0.172 | 0.0818 | No |
| 166 | Polq | 13974 | -0.176 | 0.0781 | No |
| 167 | Jpt1 | 14007 | -0.178 | 0.0809 | No |
| 168 | Snrpd1 | 14066 | -0.180 | 0.0824 | No |
| 169 | Dmd | 14142 | -0.185 | 0.0832 | No |
| 170 | Tacc3 | 14303 | -0.193 | 0.0799 | No |
| 171 | Traip | 14661 | -0.212 | 0.0669 | No |
| 172 | Brca2 | 14842 | -0.222 | 0.0633 | No |
| 173 | Rpa2 | 14843 | -0.222 | 0.0688 | No |
| 174 | Mnat1 | 14908 | -0.226 | 0.0712 | No |
| 175 | H2ax | 15267 | -0.243 | 0.0590 | No |
| 176 | H2az2 | 15275 | -0.243 | 0.0647 | No |
| 177 | Kif22 | 15382 | -0.251 | 0.0656 | No |
| 178 | E2f4 | 15399 | -0.252 | 0.0711 | No |
| 179 | Efna5 | 15621 | -0.264 | 0.0664 | No |
| 180 | Tgfb1 | 15794 | -0.272 | 0.0644 | No |
| 181 | Cenpa | 16080 | -0.288 | 0.0571 | No |
| 182 | Bub3 | 16227 | -0.297 | 0.0571 | No |
| 183 | Birc5 | 16721 | -0.329 | 0.0401 | No |
| 184 | Ube2c | 16820 | -0.334 | 0.0435 | No |
| 185 | Cdc20 | 16875 | -0.337 | 0.0491 | No |
| 186 | E2f2 | 16925 | -0.341 | 0.0552 | No |
| 187 | Hmgb3 | 17006 | -0.345 | 0.0597 | No |
| 188 | Cdk4 | 17024 | -0.347 | 0.0675 | No |
| 189 | Gins2 | 17031 | -0.347 | 0.0759 | No |
| 190 | Hmga1b | 17996 | -0.429 | 0.0374 | No |
| 191 | Pura | 18103 | -0.440 | 0.0430 | No |
| 192 | Pttg1 | 18376 | -0.473 | 0.0409 | No |
| 193 | Cdkn3 | 18582 | -0.499 | 0.0429 | No |
| 194 | Troap | 19463 | -0.709 | 0.0157 | No |

