| Dataset | CMP.CMP_Pheno.cls#Group1_versus_Group4.CMP_Pheno.cls#Group1_versus_Group4_repos |
| Phenotype | CMP_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.2765152 |
| Normalized Enrichment Score (NES) | 1.3089118 |
| Nominal p-value | 0.21730383 |
| FDR q-value | 0.39813465 |
| FWER p-Value | 0.738 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Hnrnpd | 251 | 0.676 | 0.0027 | Yes |
| 2 | Racgap1 | 265 | 0.666 | 0.0174 | Yes |
| 3 | Mcm4 | 334 | 0.639 | 0.0286 | Yes |
| 4 | Cse1l | 416 | 0.613 | 0.0386 | Yes |
| 5 | Rbbp7 | 565 | 0.563 | 0.0439 | Yes |
| 6 | Mcm2 | 655 | 0.545 | 0.0519 | Yes |
| 7 | Ipo7 | 719 | 0.532 | 0.0609 | Yes |
| 8 | Ccp110 | 822 | 0.512 | 0.0675 | Yes |
| 9 | Mcm5 | 930 | 0.497 | 0.0735 | Yes |
| 10 | Tubb5 | 1006 | 0.488 | 0.0809 | Yes |
| 11 | Srsf1 | 1121 | 0.468 | 0.0858 | Yes |
| 12 | Shmt1 | 1163 | 0.463 | 0.0944 | Yes |
| 13 | Zw10 | 1233 | 0.453 | 0.1013 | Yes |
| 14 | Wdr90 | 1235 | 0.453 | 0.1116 | Yes |
| 15 | Espl1 | 1336 | 0.441 | 0.1166 | Yes |
| 16 | Xpo1 | 1378 | 0.435 | 0.1246 | Yes |
| 17 | Pole | 1404 | 0.433 | 0.1332 | Yes |
| 18 | Smc3 | 1430 | 0.431 | 0.1419 | Yes |
| 19 | Lmnb1 | 1512 | 0.422 | 0.1475 | Yes |
| 20 | Wee1 | 1529 | 0.420 | 0.1563 | Yes |
| 21 | Nup107 | 1623 | 0.409 | 0.1610 | Yes |
| 22 | Cnot9 | 1673 | 0.404 | 0.1677 | Yes |
| 23 | Hells | 1789 | 0.394 | 0.1709 | Yes |
| 24 | Rad21 | 1822 | 0.390 | 0.1783 | Yes |
| 25 | Dnmt1 | 2079 | 0.368 | 0.1737 | Yes |
| 26 | Atad2 | 2154 | 0.364 | 0.1782 | Yes |
| 27 | Rad51c | 2182 | 0.362 | 0.1852 | Yes |
| 28 | Kif2c | 2234 | 0.357 | 0.1908 | Yes |
| 29 | Cks2 | 2242 | 0.356 | 0.1986 | Yes |
| 30 | Xrcc6 | 2305 | 0.351 | 0.2035 | Yes |
| 31 | Rad1 | 2381 | 0.345 | 0.2076 | Yes |
| 32 | Dlgap5 | 2479 | 0.337 | 0.2104 | Yes |
| 33 | Smc1a | 2558 | 0.331 | 0.2140 | Yes |
| 34 | Pcna | 2713 | 0.319 | 0.2135 | Yes |
| 35 | Mcm6 | 2786 | 0.316 | 0.2171 | Yes |
| 36 | Slbp | 2796 | 0.316 | 0.2239 | Yes |
| 37 | Mlh1 | 2962 | 0.306 | 0.2225 | Yes |
| 38 | Ncapd2 | 3002 | 0.303 | 0.2275 | Yes |
| 39 | Lbr | 3045 | 0.300 | 0.2322 | Yes |
| 40 | Bub1b | 3295 | 0.284 | 0.2261 | Yes |
| 41 | Dck | 3323 | 0.282 | 0.2312 | Yes |
| 42 | Gspt1 | 3374 | 0.279 | 0.2350 | Yes |
| 43 | Tra2b | 3506 | 0.268 | 0.2345 | Yes |
| 44 | Anp32e | 3521 | 0.266 | 0.2399 | Yes |
| 45 | Chek1 | 3765 | 0.255 | 0.2334 | Yes |
| 46 | Donson | 3823 | 0.251 | 0.2362 | Yes |
| 47 | Spag5 | 3837 | 0.250 | 0.2413 | Yes |
| 48 | Syncrip | 3966 | 0.241 | 0.2403 | Yes |
| 49 | Nolc1 | 3976 | 0.241 | 0.2454 | Yes |
| 50 | Mcm3 | 4038 | 0.238 | 0.2478 | Yes |
| 51 | Pola2 | 4430 | 0.218 | 0.2328 | Yes |
| 52 | Brca1 | 4494 | 0.214 | 0.2345 | Yes |
| 53 | Rfc1 | 4564 | 0.210 | 0.2358 | Yes |
| 54 | Pds5b | 4607 | 0.208 | 0.2385 | Yes |
| 55 | Nbn | 4614 | 0.207 | 0.2429 | Yes |
| 56 | Ilf3 | 4680 | 0.204 | 0.2443 | Yes |
| 57 | Mcm7 | 4712 | 0.202 | 0.2474 | Yes |
| 58 | Msh2 | 4758 | 0.200 | 0.2497 | Yes |
| 59 | Nup205 | 4959 | 0.189 | 0.2438 | Yes |
| 60 | Cdkn1a | 5106 | 0.180 | 0.2405 | Yes |
| 61 | Prkdc | 5110 | 0.180 | 0.2445 | Yes |
| 62 | Cbx5 | 5129 | 0.179 | 0.2477 | Yes |
| 63 | Timeless | 5225 | 0.178 | 0.2469 | Yes |
| 64 | Orc6 | 5238 | 0.177 | 0.2504 | Yes |
| 65 | Suv39h1 | 5273 | 0.175 | 0.2527 | Yes |
| 66 | H2az1 | 5301 | 0.173 | 0.2553 | Yes |
| 67 | Top2a | 5376 | 0.170 | 0.2554 | Yes |
| 68 | Aurka | 5384 | 0.170 | 0.2589 | Yes |
| 69 | Rrm2 | 5489 | 0.166 | 0.2574 | Yes |
| 70 | Prps1 | 5519 | 0.164 | 0.2597 | Yes |
| 71 | Mre11a | 5539 | 0.164 | 0.2625 | Yes |
| 72 | Cit | 5541 | 0.163 | 0.2662 | Yes |
| 73 | Tmpo | 5705 | 0.155 | 0.2615 | Yes |
| 74 | Nap1l1 | 5713 | 0.154 | 0.2647 | Yes |
| 75 | Cdc25a | 5727 | 0.154 | 0.2675 | Yes |
| 76 | Rad51ap1 | 5784 | 0.151 | 0.2682 | Yes |
| 77 | Nasp | 5893 | 0.146 | 0.2660 | Yes |
| 78 | Pms2 | 5914 | 0.145 | 0.2683 | Yes |
| 79 | Ubr7 | 5919 | 0.145 | 0.2714 | Yes |
| 80 | Eed | 5927 | 0.144 | 0.2744 | Yes |
| 81 | Srsf2 | 5962 | 0.143 | 0.2760 | Yes |
| 82 | Plk1 | 6051 | 0.139 | 0.2747 | Yes |
| 83 | Kif18b | 6078 | 0.138 | 0.2765 | Yes |
| 84 | Mki67 | 6145 | 0.135 | 0.2762 | No |
| 85 | Nup153 | 6267 | 0.130 | 0.2731 | No |
| 86 | Asf1b | 6320 | 0.128 | 0.2733 | No |
| 87 | Nop56 | 6420 | 0.122 | 0.2711 | No |
| 88 | Cdc25b | 6446 | 0.121 | 0.2726 | No |
| 89 | Tipin | 6738 | 0.113 | 0.2603 | No |
| 90 | Psip1 | 7113 | 0.098 | 0.2435 | No |
| 91 | Prim2 | 7183 | 0.094 | 0.2421 | No |
| 92 | Mybl2 | 7235 | 0.092 | 0.2416 | No |
| 93 | Tubg1 | 7275 | 0.090 | 0.2417 | No |
| 94 | Cenpe | 7288 | 0.090 | 0.2432 | No |
| 95 | Exosc8 | 7317 | 0.089 | 0.2438 | No |
| 96 | Lsm8 | 7636 | 0.076 | 0.2293 | No |
| 97 | Eif2s1 | 7662 | 0.075 | 0.2297 | No |
| 98 | Aurkb | 7751 | 0.071 | 0.2269 | No |
| 99 | Stmn1 | 7806 | 0.068 | 0.2257 | No |
| 100 | Pa2g4 | 7820 | 0.067 | 0.2266 | No |
| 101 | Dut | 7841 | 0.066 | 0.2271 | No |
| 102 | Lig1 | 7916 | 0.063 | 0.2247 | No |
| 103 | Pole4 | 8004 | 0.059 | 0.2217 | No |
| 104 | Paics | 8026 | 0.059 | 0.2219 | No |
| 105 | Melk | 8029 | 0.058 | 0.2232 | No |
| 106 | Ube2s | 8050 | 0.058 | 0.2235 | No |
| 107 | Ranbp1 | 8171 | 0.052 | 0.2185 | No |
| 108 | Rpa1 | 8179 | 0.052 | 0.2194 | No |
| 109 | Ddx39a | 8212 | 0.051 | 0.2189 | No |
| 110 | Ctcf | 8337 | 0.046 | 0.2136 | No |
| 111 | Pold1 | 8447 | 0.042 | 0.2090 | No |
| 112 | Ssrp1 | 8683 | 0.033 | 0.1978 | No |
| 113 | Bard1 | 8720 | 0.031 | 0.1967 | No |
| 114 | Mms22l | 8931 | 0.023 | 0.1865 | No |
| 115 | Spc25 | 9055 | 0.018 | 0.1806 | No |
| 116 | Ccnb2 | 9065 | 0.018 | 0.1806 | No |
| 117 | Tk1 | 9285 | 0.009 | 0.1696 | No |
| 118 | Pold3 | 9503 | 0.000 | 0.1585 | No |
| 119 | Rad50 | 9693 | -0.003 | 0.1489 | No |
| 120 | Lyar | 9694 | -0.003 | 0.1490 | No |
| 121 | Kif4 | 9964 | -0.013 | 0.1355 | No |
| 122 | Stag1 | 9972 | -0.014 | 0.1355 | No |
| 123 | Cdca8 | 9986 | -0.014 | 0.1352 | No |
| 124 | Prdx4 | 10013 | -0.015 | 0.1342 | No |
| 125 | Hus1 | 10086 | -0.017 | 0.1309 | No |
| 126 | Pnn | 10093 | -0.018 | 0.1310 | No |
| 127 | Ezh2 | 10284 | -0.025 | 0.1219 | No |
| 128 | Phf5a | 10297 | -0.025 | 0.1218 | No |
| 129 | Smc4 | 10336 | -0.027 | 0.1205 | No |
| 130 | Gins4 | 10426 | -0.031 | 0.1167 | No |
| 131 | Cdkn2c | 10600 | -0.038 | 0.1087 | No |
| 132 | Diaph3 | 10614 | -0.038 | 0.1089 | No |
| 133 | Tbrg4 | 10640 | -0.039 | 0.1085 | No |
| 134 | Chek2 | 10775 | -0.045 | 0.1027 | No |
| 135 | Asf1a | 10831 | -0.047 | 0.1010 | No |
| 136 | Ppp1r8 | 10892 | -0.050 | 0.0991 | No |
| 137 | E2f8 | 10966 | -0.053 | 0.0966 | No |
| 138 | Ak2 | 11101 | -0.058 | 0.0911 | No |
| 139 | Mad2l1 | 11173 | -0.061 | 0.0889 | No |
| 140 | Ccne1 | 11239 | -0.064 | 0.0870 | No |
| 141 | Luc7l3 | 11474 | -0.074 | 0.0768 | No |
| 142 | Hmmr | 11613 | -0.080 | 0.0716 | No |
| 143 | Cdkn1b | 11654 | -0.082 | 0.0714 | No |
| 144 | Ing3 | 11664 | -0.082 | 0.0728 | No |
| 145 | Trp53 | 11669 | -0.082 | 0.0745 | No |
| 146 | Dek | 11904 | -0.092 | 0.0647 | No |
| 147 | Cdkn2a | 12046 | -0.098 | 0.0597 | No |
| 148 | Hmgb2 | 12447 | -0.116 | 0.0420 | No |
| 149 | Ube2t | 12869 | -0.131 | 0.0235 | No |
| 150 | Plk4 | 12925 | -0.134 | 0.0238 | No |
| 151 | Cdk1 | 12998 | -0.137 | 0.0232 | No |
| 152 | Myc | 13024 | -0.139 | 0.0252 | No |
| 153 | Smc6 | 13066 | -0.140 | 0.0263 | No |
| 154 | Brms1l | 13069 | -0.141 | 0.0294 | No |
| 155 | Trip13 | 13078 | -0.141 | 0.0322 | No |
| 156 | Cks1b | 13329 | -0.151 | 0.0230 | No |
| 157 | Dctpp1 | 13366 | -0.153 | 0.0246 | No |
| 158 | Rfc2 | 13464 | -0.158 | 0.0233 | No |
| 159 | Usp1 | 13739 | -0.169 | 0.0132 | No |
| 160 | Ung | 13803 | -0.172 | 0.0139 | No |
| 161 | Jpt1 | 14007 | -0.178 | 0.0077 | No |
| 162 | Dscc1 | 14044 | -0.179 | 0.0099 | No |
| 163 | Depdc1a | 14111 | -0.183 | 0.0108 | No |
| 164 | Nudt21 | 14131 | -0.184 | 0.0141 | No |
| 165 | Gins1 | 14148 | -0.185 | 0.0175 | No |
| 166 | Rfc3 | 14180 | -0.187 | 0.0202 | No |
| 167 | Tacc3 | 14303 | -0.193 | 0.0184 | No |
| 168 | Dclre1b | 14744 | -0.217 | 0.0009 | No |
| 169 | Cenpm | 14765 | -0.218 | 0.0049 | No |
| 170 | Spc24 | 14803 | -0.220 | 0.0081 | No |
| 171 | Brca2 | 14842 | -0.222 | 0.0113 | No |
| 172 | Rpa2 | 14843 | -0.222 | 0.0164 | No |
| 173 | Orc2 | 14900 | -0.225 | 0.0187 | No |
| 174 | H2ax | 15267 | -0.243 | 0.0056 | No |
| 175 | Kif22 | 15382 | -0.251 | 0.0055 | No |
| 176 | Ran | 15573 | -0.261 | 0.0018 | No |
| 177 | Psmc3ip | 15630 | -0.265 | 0.0050 | No |
| 178 | Mxd3 | 15803 | -0.272 | 0.0025 | No |
| 179 | Gins3 | 16150 | -0.292 | -0.0084 | No |
| 180 | Pan2 | 16610 | -0.324 | -0.0244 | No |
| 181 | Pold2 | 16684 | -0.328 | -0.0206 | No |
| 182 | Birc5 | 16721 | -0.329 | -0.0149 | No |
| 183 | Nme1 | 16822 | -0.334 | -0.0123 | No |
| 184 | Cdc20 | 16875 | -0.337 | -0.0072 | No |
| 185 | Tfrc | 16878 | -0.337 | 0.0004 | No |
| 186 | Hmgb3 | 17006 | -0.345 | 0.0019 | No |
| 187 | Cdk4 | 17024 | -0.347 | 0.0090 | No |
| 188 | Mthfd2 | 17523 | -0.389 | -0.0075 | No |
| 189 | Hmga1b | 17996 | -0.429 | -0.0218 | No |
| 190 | Pttg1 | 18376 | -0.473 | -0.0302 | No |
| 191 | Rnaseh2a | 18413 | -0.477 | -0.0211 | No |
| 192 | Ppm1d | 18467 | -0.482 | -0.0127 | No |
| 193 | Cdkn3 | 18582 | -0.499 | -0.0071 | No |
| 194 | Snrpb | 18585 | -0.499 | 0.0043 | No |
| 195 | Pop7 | 18749 | -0.524 | 0.0080 | No |
| 196 | Rpa3 | 19011 | -0.575 | 0.0079 | No |
| 197 | Tcf19 | 19142 | -0.608 | 0.0153 | No |
| 198 | Cdca3 | 19505 | -0.731 | 0.0136 | No |

