| Dataset | CMP.CMP_Pheno.cls#Group1_versus_Group4.CMP_Pheno.cls#Group1_versus_Group4_repos |
| Phenotype | CMP_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | -0.30428198 |
| Normalized Enrichment Score (NES) | -1.2873014 |
| Nominal p-value | 0.13 |
| FDR q-value | 0.33697507 |
| FWER p-Value | 0.776 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ccr5 | 173 | 0.718 | 0.0095 | No |
| 2 | Il2ra | 631 | 0.550 | 0.0002 | No |
| 3 | Fas | 650 | 0.547 | 0.0132 | No |
| 4 | F2r | 938 | 0.495 | 0.0112 | No |
| 5 | Il7 | 1534 | 0.420 | -0.0084 | No |
| 6 | Bcat1 | 1575 | 0.414 | 0.0001 | No |
| 7 | Mrpl3 | 1639 | 0.408 | 0.0073 | No |
| 8 | Ube2n | 1833 | 0.389 | 0.0074 | No |
| 9 | Crtam | 1984 | 0.375 | 0.0093 | No |
| 10 | Zap70 | 2241 | 0.356 | 0.0053 | No |
| 11 | Ache | 2421 | 0.342 | 0.0049 | No |
| 12 | Akt1 | 2443 | 0.339 | 0.0125 | No |
| 13 | Mmp9 | 2618 | 0.325 | 0.0119 | No |
| 14 | Trat1 | 2969 | 0.305 | 0.0019 | No |
| 15 | Eif3j1 | 3039 | 0.301 | 0.0060 | No |
| 16 | H2-Ob | 3073 | 0.298 | 0.0120 | No |
| 17 | Cd1d2 | 3114 | 0.295 | 0.0174 | No |
| 18 | Itgal | 3121 | 0.294 | 0.0246 | No |
| 19 | Il18 | 3132 | 0.293 | 0.0316 | No |
| 20 | Il6 | 3188 | 0.290 | 0.0362 | No |
| 21 | Cd247 | 3419 | 0.275 | 0.0315 | No |
| 22 | Abce1 | 3613 | 0.262 | 0.0283 | No |
| 23 | Galnt1 | 3614 | 0.262 | 0.0350 | No |
| 24 | Tap1 | 3668 | 0.259 | 0.0389 | No |
| 25 | Itgb2 | 3712 | 0.256 | 0.0433 | No |
| 26 | Hif1a | 3775 | 0.254 | 0.0466 | No |
| 27 | Map3k7 | 4268 | 0.226 | 0.0273 | No |
| 28 | Eif3a | 4323 | 0.223 | 0.0302 | No |
| 29 | Flna | 4352 | 0.221 | 0.0344 | No |
| 30 | Brca1 | 4494 | 0.214 | 0.0327 | No |
| 31 | H2-Oa | 4511 | 0.213 | 0.0373 | No |
| 32 | Cd79a | 4616 | 0.207 | 0.0373 | No |
| 33 | Nlrp3 | 4685 | 0.204 | 0.0391 | No |
| 34 | Abi1 | 4731 | 0.202 | 0.0419 | No |
| 35 | Cd80 | 5035 | 0.184 | 0.0312 | No |
| 36 | Jak2 | 5043 | 0.184 | 0.0355 | No |
| 37 | C2 | 5248 | 0.176 | 0.0296 | No |
| 38 | Stab1 | 5292 | 0.174 | 0.0318 | No |
| 39 | Ly75 | 5341 | 0.172 | 0.0337 | No |
| 40 | Wars1 | 5446 | 0.167 | 0.0327 | No |
| 41 | Irf4 | 5557 | 0.163 | 0.0312 | No |
| 42 | Ccr1 | 5584 | 0.161 | 0.0340 | No |
| 43 | Ets1 | 5812 | 0.150 | 0.0263 | No |
| 44 | Csf1 | 6022 | 0.141 | 0.0192 | No |
| 45 | Ccr2 | 6187 | 0.133 | 0.0143 | No |
| 46 | Socs1 | 6209 | 0.132 | 0.0166 | No |
| 47 | Egfr | 6620 | 0.114 | -0.0014 | No |
| 48 | Tgfb2 | 6905 | 0.106 | -0.0132 | No |
| 49 | Tap2 | 7078 | 0.099 | -0.0194 | No |
| 50 | Fcgr2b | 7249 | 0.092 | -0.0258 | No |
| 51 | Il12a | 7323 | 0.089 | -0.0272 | No |
| 52 | H2-DMb2 | 7471 | 0.082 | -0.0326 | No |
| 53 | Traf2 | 7519 | 0.081 | -0.0330 | No |
| 54 | Tpd52 | 7535 | 0.080 | -0.0317 | No |
| 55 | Eif4g3 | 7782 | 0.069 | -0.0425 | No |
| 56 | Hcls1 | 7872 | 0.065 | -0.0453 | No |
| 57 | Il27ra | 8045 | 0.058 | -0.0526 | No |
| 58 | Irf8 | 8071 | 0.057 | -0.0525 | No |
| 59 | Il10 | 8103 | 0.056 | -0.0526 | No |
| 60 | Capg | 8328 | 0.047 | -0.0629 | No |
| 61 | Csk | 8695 | 0.032 | -0.0807 | No |
| 62 | Socs5 | 9039 | 0.019 | -0.0977 | No |
| 63 | Ccnd2 | 9078 | 0.017 | -0.0992 | No |
| 64 | Gcnt1 | 9091 | 0.017 | -0.0994 | No |
| 65 | Il1b | 9217 | 0.011 | -0.1054 | No |
| 66 | Hdac9 | 9658 | -0.001 | -0.1278 | No |
| 67 | Il11 | 9768 | -0.006 | -0.1333 | No |
| 68 | Ptprc | 10539 | -0.035 | -0.1716 | No |
| 69 | Tapbp | 10574 | -0.037 | -0.1724 | No |
| 70 | Bcl3 | 10792 | -0.045 | -0.1823 | No |
| 71 | Ltb | 10970 | -0.053 | -0.1900 | No |
| 72 | Ifngr1 | 10986 | -0.053 | -0.1894 | No |
| 73 | Cd47 | 11110 | -0.058 | -0.1941 | No |
| 74 | Itk | 11172 | -0.061 | -0.1957 | No |
| 75 | Il15 | 11491 | -0.075 | -0.2100 | No |
| 76 | Ccl5 | 11496 | -0.075 | -0.2083 | No |
| 77 | Glmn | 11593 | -0.080 | -0.2111 | No |
| 78 | Fgr | 11916 | -0.093 | -0.2252 | No |
| 79 | Il4ra | 11965 | -0.095 | -0.2252 | No |
| 80 | Cdkn2a | 12046 | -0.098 | -0.2268 | No |
| 81 | Stat1 | 12073 | -0.099 | -0.2256 | No |
| 82 | Prkcb | 12237 | -0.107 | -0.2312 | No |
| 83 | Ripk2 | 13178 | -0.145 | -0.2754 | No |
| 84 | Il12rb1 | 13244 | -0.148 | -0.2749 | No |
| 85 | Icam1 | 13290 | -0.150 | -0.2734 | No |
| 86 | Map4k1 | 13355 | -0.153 | -0.2727 | No |
| 87 | St8sia4 | 13381 | -0.154 | -0.2701 | No |
| 88 | Lcp2 | 13387 | -0.154 | -0.2664 | No |
| 89 | Acvr2a | 13735 | -0.169 | -0.2798 | No |
| 90 | Ikbkb | 13746 | -0.170 | -0.2760 | No |
| 91 | Il16 | 13802 | -0.172 | -0.2744 | No |
| 92 | Nck1 | 14132 | -0.184 | -0.2865 | No |
| 93 | Tlr3 | 14373 | -0.197 | -0.2937 | No |
| 94 | Cd96 | 14423 | -0.200 | -0.2911 | No |
| 95 | Rpl9 | 14496 | -0.204 | -0.2895 | No |
| 96 | Lyn | 14741 | -0.217 | -0.2964 | No |
| 97 | Spi1 | 14896 | -0.225 | -0.2985 | Yes |
| 98 | Tlr6 | 14916 | -0.226 | -0.2938 | Yes |
| 99 | Bcl10 | 15014 | -0.232 | -0.2928 | Yes |
| 100 | Ncf4 | 15017 | -0.232 | -0.2870 | Yes |
| 101 | Lck | 15093 | -0.236 | -0.2848 | Yes |
| 102 | Apbb1 | 15125 | -0.238 | -0.2803 | Yes |
| 103 | Npm1 | 15224 | -0.242 | -0.2791 | Yes |
| 104 | Il2 | 15239 | -0.242 | -0.2737 | Yes |
| 105 | Tnf | 15292 | -0.244 | -0.2701 | Yes |
| 106 | Ifngr2 | 15404 | -0.252 | -0.2693 | Yes |
| 107 | Tlr1 | 15428 | -0.254 | -0.2640 | Yes |
| 108 | Il18rap | 15430 | -0.254 | -0.2576 | Yes |
| 109 | Thy1 | 15433 | -0.254 | -0.2512 | Yes |
| 110 | Mtif2 | 15462 | -0.256 | -0.2461 | Yes |
| 111 | Stat4 | 15508 | -0.258 | -0.2418 | Yes |
| 112 | Il2rg | 15532 | -0.259 | -0.2364 | Yes |
| 113 | Elf4 | 15717 | -0.269 | -0.2389 | Yes |
| 114 | Tgfb1 | 15794 | -0.272 | -0.2359 | Yes |
| 115 | Prkcg | 15955 | -0.281 | -0.2368 | Yes |
| 116 | Icosl | 15986 | -0.283 | -0.2312 | Yes |
| 117 | Degs1 | 16042 | -0.286 | -0.2267 | Yes |
| 118 | Inhba | 16289 | -0.302 | -0.2315 | Yes |
| 119 | Eif3d | 16454 | -0.314 | -0.2319 | Yes |
| 120 | Ly86 | 16720 | -0.329 | -0.2370 | Yes |
| 121 | Nme1 | 16822 | -0.334 | -0.2336 | Yes |
| 122 | Cd86 | 17085 | -0.352 | -0.2380 | Yes |
| 123 | Rps3a1 | 17164 | -0.359 | -0.2328 | Yes |
| 124 | Igsf6 | 17276 | -0.369 | -0.2291 | Yes |
| 125 | Ptpn6 | 17297 | -0.370 | -0.2206 | Yes |
| 126 | Lif | 17566 | -0.392 | -0.2243 | Yes |
| 127 | Cd4 | 17645 | -0.399 | -0.2181 | Yes |
| 128 | Was | 17699 | -0.402 | -0.2106 | Yes |
| 129 | Eif5a | 17708 | -0.403 | -0.2007 | Yes |
| 130 | Rpl3l | 17715 | -0.403 | -0.1907 | Yes |
| 131 | H2-DMa | 17732 | -0.405 | -0.1812 | Yes |
| 132 | Cd74 | 17735 | -0.405 | -0.1710 | Yes |
| 133 | Cfp | 17750 | -0.406 | -0.1614 | Yes |
| 134 | Rps9 | 17880 | -0.417 | -0.1573 | Yes |
| 135 | Cd28 | 17995 | -0.429 | -0.1522 | Yes |
| 136 | Psmb10 | 18094 | -0.439 | -0.1460 | Yes |
| 137 | Tlr2 | 18171 | -0.447 | -0.1385 | Yes |
| 138 | Srgn | 18183 | -0.448 | -0.1276 | Yes |
| 139 | H2-Aa | 18391 | -0.475 | -0.1261 | Yes |
| 140 | Ube2d1 | 18400 | -0.475 | -0.1143 | Yes |
| 141 | Pf4 | 18532 | -0.492 | -0.1085 | Yes |
| 142 | Ifnar2 | 18538 | -0.493 | -0.0962 | Yes |
| 143 | Cxcl9 | 18598 | -0.501 | -0.0864 | Yes |
| 144 | Dyrk3 | 18725 | -0.522 | -0.0795 | Yes |
| 145 | Gpr65 | 18926 | -0.558 | -0.0755 | Yes |
| 146 | Irf7 | 19212 | -0.627 | -0.0740 | Yes |
| 147 | B2m | 19344 | -0.663 | -0.0638 | Yes |
| 148 | Elane | 19488 | -0.721 | -0.0527 | Yes |
| 149 | Il4 | 19644 | -0.844 | -0.0391 | Yes |
| 150 | Ccnd3 | 19648 | -0.848 | -0.0176 | Yes |
| 151 | Ctss | 19700 | -0.935 | 0.0036 | Yes |

