Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	CMP.CMP_Pheno.cls#Group1_versus_Group3.CMP_Pheno.cls#Group1_versus_Group3_repos
Phenotype	CMP_Pheno.cls#Group1_versus_Group3_repos
Upregulated in class	2
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.235218
Normalized Enrichment Score (NES)	-1.0653104
Nominal p-value	0.36237624
FDR q-value	0.845023
FWER p-Value	0.991

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Prkaa2	300	0.596	0.0178	No
2	Hsp90b1	1277	0.400	-0.0096	No
3	Adcy2	1315	0.396	0.0105	No
4	Ube2n	1652	0.359	0.0133	No
5	Ptpn11	1911	0.337	0.0189	No
6	Mapk10	2563	0.291	0.0020	No
7	Pikfyve	2866	0.271	0.0017	No
8	Cab39	2943	0.267	0.0126	No
9	Pin1	2981	0.264	0.0254	No
10	Cdk2	3028	0.261	0.0375	No
11	Cltc	3035	0.261	0.0517	No
12	Actr2	4144	0.200	0.0065	No
13	Mapk8	4335	0.191	0.0075	No
14	Map3k7	4464	0.184	0.0112	No
15	Calr	5205	0.151	-0.0180	No
16	Stat2	5273	0.148	-0.0132	No
17	Grk2	5296	0.147	-0.0062	No
18	Pak4	5489	0.137	-0.0083	No
19	Arf1	5496	0.137	-0.0010	No
20	Pten	5551	0.135	0.0037	No
21	Cdkn1b	5586	0.134	0.0094	No
22	Gsk3b	5988	0.119	-0.0044	No
23	Smad2	6071	0.116	-0.0021	No
24	Raf1	6280	0.111	-0.0065	No
25	Mapk1	6586	0.098	-0.0166	No
26	Rit1	7140	0.078	-0.0404	No
27	Tbk1	7164	0.078	-0.0372	No
28	Plcb1	7180	0.077	-0.0337	No
29	Pdk1	7611	0.059	-0.0523	No
30	Tiam1	7720	0.056	-0.0547	No
31	Atf1	7940	0.049	-0.0631	No
32	Grb2	8000	0.047	-0.0635	No
33	Mapk9	8097	0.043	-0.0660	No
34	Plcg1	8111	0.043	-0.0642	No
35	E2f1	8147	0.042	-0.0637	No
36	Prkag1	8261	0.038	-0.0674	No
37	Nck1	8717	0.021	-0.0893	No
38	Itpr2	8747	0.020	-0.0897	No
39	Rptor	8869	0.015	-0.0950	No
40	Prkar2a	8968	0.011	-0.0993	No
41	Vav3	9256	0.001	-0.1139	No
42	Map2k6	9667	-0.011	-0.1341	No
43	Rps6ka3	9746	-0.015	-0.1372	No
44	Ube2d3	9747	-0.015	-0.1364	No
45	Ripk1	9950	-0.022	-0.1454	No
46	Prkcb	10236	-0.033	-0.1581	No
47	Mapkap1	10344	-0.037	-0.1615	No
48	Trib3	10358	-0.038	-0.1600	No
49	Sqstm1	10451	-0.041	-0.1624	No
50	Pla2g12a	10686	-0.049	-0.1716	No
51	Ppp2r1b	10774	-0.052	-0.1732	No
52	Mknk2	10807	-0.053	-0.1719	No
53	Myd88	10969	-0.058	-0.1768	No
54	Actr3	10980	-0.059	-0.1740	No
55	Map2k3	11087	-0.060	-0.1761	No
56	Arpc3	11277	-0.068	-0.1819	No
57	Akt1	11292	-0.068	-0.1789	No
58	Arhgdia	11377	-0.072	-0.1791	No
59	Them4	11666	-0.083	-0.1892	No
60	Dusp3	11907	-0.094	-0.1962	No
61	Tnfrsf1a	11946	-0.096	-0.1928	No
62	Cdk1	12127	-0.103	-0.1962	No
63	Cdkn1a	12166	-0.105	-0.1923	No
64	Eif4e	12272	-0.109	-0.1916	No
65	Ywhab	12777	-0.129	-0.2101	No
66	Cxcr4	12834	-0.131	-0.2056	No
67	Acaca	13197	-0.145	-0.2160	No
68	Sla	13424	-0.155	-0.2189	No
69	Dapp1	13600	-0.162	-0.2188	No
70	Traf2	13708	-0.167	-0.2150	No
71	Akt1s1	13729	-0.168	-0.2067	No
72	Tsc2	13930	-0.177	-0.2070	No
73	Pfn1	14059	-0.184	-0.2033	No
74	Nod1	14092	-0.186	-0.1946	No
75	Rac1	14368	-0.200	-0.1975	No
76	Egfr	15111	-0.237	-0.2221	Yes
77	Rps6ka1	15168	-0.238	-0.2117	Yes
78	Ap2m1	15212	-0.240	-0.2006	Yes
79	Nfkbib	15278	-0.242	-0.1904	Yes
80	Irak4	15306	-0.244	-0.1783	Yes
81	Cab39l	15384	-0.248	-0.1684	Yes
82	Mknk1	15461	-0.252	-0.1583	Yes
83	Ppp1ca	15559	-0.258	-0.1489	Yes
84	Hras	15564	-0.258	-0.1348	Yes
85	Slc2a1	15606	-0.259	-0.1225	Yes
86	Gna14	15928	-0.281	-0.1232	Yes
87	Pik3r3	16044	-0.288	-0.1131	Yes
88	Lck	16097	-0.291	-0.0996	Yes
89	Camk4	16510	-0.317	-0.1029	Yes
90	Cdk4	16570	-0.321	-0.0881	Yes
91	Sfn	16622	-0.325	-0.0727	Yes
92	Csnk2b	17010	-0.352	-0.0728	Yes
93	Il2rg	17153	-0.362	-0.0599	Yes
94	Ralb	17348	-0.379	-0.0488	Yes
95	Il4	18528	-0.496	-0.0812	Yes
96	Pitx2	18695	-0.519	-0.0608	Yes
97	Ddit3	19255	-0.636	-0.0539	Yes
98	Cfl1	19391	-0.682	-0.0230	Yes
99	Ecsit	19542	-0.761	0.0116	Yes