Details for gene set HALLMARK_KRAS_SIGNALING

Table: GSEA Results Summary

Dataset	CMP.CMP_Pheno.cls#Group1_versus_Group3.CMP_Pheno.cls#Group1_versus_Group3_repos
Phenotype	CMP_Pheno.cls#Group1_versus_Group3_repos
Upregulated in class	2
GeneSet	HALLMARK_KRAS_SIGNALING_UP
Enrichment Score (ES)	-0.2595957
Normalized Enrichment Score (NES)	-1.1683685
Nominal p-value	0.206
FDR q-value	0.85578465
FWER p-Value	0.934

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Tmem100	131	0.709	0.0143	No
2	Adam17	516	0.524	0.0102	No
3	Kif5c	871	0.459	0.0057	No
4	Ppp1r15a	877	0.457	0.0190	No
5	Ccser2	1365	0.389	0.0057	No
6	Ptprr	1413	0.381	0.0146	No
7	Cdadc1	1567	0.366	0.0176	No
8	Pdcd1lg2	1600	0.363	0.0267	No
9	Prdm1	2193	0.316	0.0059	No
10	Prkg2	2408	0.302	0.0039	No
11	Dcbld2	2423	0.301	0.0121	No
12	Trib1	2477	0.297	0.0182	No
13	Mafb	2592	0.291	0.0210	No
14	Fbxo4	2622	0.289	0.0281	No
15	Tfpi	2705	0.281	0.0322	No
16	Ly96	2805	0.275	0.0353	No
17	F2rl1	2847	0.272	0.0413	No
18	Nr0b2	2895	0.269	0.0468	No
19	Gabra3	3016	0.262	0.0485	No
20	Ano1	3309	0.243	0.0408	No
21	Hbegf	3417	0.238	0.0424	No
22	Snap91	3437	0.237	0.0484	No
23	Zfp277	3711	0.222	0.0411	No
24	Strn	3869	0.214	0.0394	No
25	Avl9	4558	0.180	0.0096	No
26	Cmklr1	4565	0.180	0.0146	No
27	Tor1aip2	4566	0.180	0.0200	No
28	Il1b	4620	0.178	0.0225	No
29	Sdccag8	4693	0.175	0.0240	No
30	Scn1b	4840	0.168	0.0216	No
31	Ptgs2	4927	0.164	0.0220	No
32	Gucy1a1	4984	0.161	0.0240	No
33	Mtmr10	5268	0.148	0.0139	No
34	Rbm4	5271	0.148	0.0182	No
35	Etv1	5291	0.147	0.0216	No
36	Il7r	5602	0.134	0.0097	No
37	Spp1	5670	0.131	0.0102	No
38	Il1rl2	5960	0.120	-0.0010	No
39	Clec4a3	6114	0.114	-0.0054	No
40	Itgbl1	6141	0.114	-0.0034	No
41	Cbx8	6325	0.109	-0.0095	No
42	Usp12	6358	0.107	-0.0079	No
43	Yrdc	6536	0.100	-0.0140	No
44	H2bc3	6571	0.099	-0.0128	No
45	Map7	6801	0.090	-0.0218	No
46	G0s2	6806	0.090	-0.0194	No
47	Plau	6913	0.086	-0.0222	No
48	Klf4	6955	0.085	-0.0218	No
49	Vwa5a	7066	0.080	-0.0250	No
50	Cbl	7072	0.080	-0.0229	No
51	Scg5	7237	0.074	-0.0291	No
52	Tspan13	7470	0.065	-0.0390	No
53	Nin	7542	0.062	-0.0408	No
54	Tnfrsf1b	7668	0.058	-0.0455	No
55	Cxcl10	7927	0.050	-0.0571	No
56	Ero1a	7941	0.049	-0.0563	No
57	Ank	7970	0.048	-0.0564	No
58	Mmp9	8079	0.044	-0.0606	No
59	Glrx	8275	0.037	-0.0694	No
60	Bpgm	8401	0.032	-0.0748	No
61	Wdr33	8568	0.027	-0.0825	No
62	Btbd3	8629	0.024	-0.0848	No
63	Adgra2	8688	0.022	-0.0871	No
64	Tlr8	8735	0.020	-0.0889	No
65	Itga2	8888	0.014	-0.0962	No
66	Lat2	8915	0.014	-0.0971	No
67	Aldh1a2	9281	0.000	-0.1157	No
68	Lif	9292	0.000	-0.1162	No
69	Epb41l3	9448	-0.003	-0.1240	No
70	Birc3	9692	-0.013	-0.1361	No
71	Id2	9795	-0.017	-0.1408	No
72	Ptbp2	9809	-0.017	-0.1409	No
73	Crot	9849	-0.019	-0.1423	No
74	Irf8	9980	-0.023	-0.1483	No
75	Ets1	10257	-0.034	-0.1613	No
76	Dock2	10350	-0.037	-0.1649	No
77	Pecam1	10550	-0.044	-0.1738	No
78	Adam8	10552	-0.044	-0.1725	No
79	Gfpt2	10754	-0.051	-0.1812	No
80	Eng	10778	-0.052	-0.1809	No
81	Akt2	10892	-0.056	-0.1850	No
82	Dusp6	10937	-0.058	-0.1855	No
83	Laptm5	11117	-0.061	-0.1928	No
84	Plvap	11650	-0.083	-0.2175	No
85	Scg3	11680	-0.084	-0.2165	No
86	Mycn	11685	-0.084	-0.2142	No
87	Map3k1	11895	-0.093	-0.2221	No
88	Ikzf1	11979	-0.097	-0.2235	No
89	Gpnmb	12449	-0.116	-0.2439	No
90	Lcp1	12707	-0.126	-0.2533	No
91	Evi5	12737	-0.127	-0.2510	No
92	Il10ra	12766	-0.129	-0.2486	No
93	Cxcr4	12834	-0.131	-0.2482	No
94	Flt4	12852	-0.133	-0.2451	No
95	Satb1	12902	-0.134	-0.2436	No
96	Ccnd2	12905	-0.134	-0.2398	No
97	Ephb2	12951	-0.136	-0.2380	No
98	Spry2	12971	-0.137	-0.2349	No
99	Trib2	13166	-0.143	-0.2406	No
100	Map4k1	13246	-0.147	-0.2403	No
101	Angptl4	13457	-0.156	-0.2464	No
102	Ptcd2	13536	-0.159	-0.2456	No
103	Inhba	13733	-0.168	-0.2506	No
104	Mmp11	13796	-0.171	-0.2488	No
105	Mmd	13913	-0.176	-0.2495	No
106	Atg10	14113	-0.187	-0.2541	Yes
107	Dnmbp	14208	-0.191	-0.2532	Yes
108	Wnt7a	14232	-0.192	-0.2487	Yes
109	Plaur	14288	-0.195	-0.2457	Yes
110	Gprc5b	14463	-0.205	-0.2485	Yes
111	Adgrl4	14476	-0.206	-0.2431	Yes
112	Rabgap1l	14639	-0.213	-0.2450	Yes
113	Tspan7	14646	-0.214	-0.2390	Yes
114	Gng11	14704	-0.216	-0.2355	Yes
115	St6gal1	14768	-0.219	-0.2322	Yes
116	Hsd11b1	14772	-0.219	-0.2259	Yes
117	Ammecr1	14845	-0.224	-0.2229	Yes
118	Zfp639	14896	-0.226	-0.2188	Yes
119	Nr1h4	14990	-0.231	-0.2167	Yes
120	Cbr4	15172	-0.238	-0.2189	Yes
121	Tmem176a	15194	-0.239	-0.2128	Yes
122	Prelid3b	15311	-0.244	-0.2115	Yes
123	Cab39l	15384	-0.248	-0.2079	Yes
124	Itgb2	15741	-0.266	-0.2181	Yes
125	Etv4	16206	-0.298	-0.2330	Yes
126	Btc	16309	-0.304	-0.2292	Yes
127	Abcb1a	16334	-0.306	-0.2213	Yes
128	Cfb	16386	-0.309	-0.2148	Yes
129	Car2	16453	-0.313	-0.2089	Yes
130	Tmem176b	16527	-0.318	-0.2032	Yes
131	Tmem158	16593	-0.323	-0.1970	Yes
132	F13a1	16752	-0.333	-0.1952	Yes
133	Akap12	16812	-0.338	-0.1882	Yes
134	Spon1	16849	-0.340	-0.1799	Yes
135	Ppbp	17021	-0.353	-0.1782	Yes
136	Etv5	17038	-0.354	-0.1685	Yes
137	Psmb8	17078	-0.357	-0.1600	Yes
138	Il2rg	17153	-0.362	-0.1530	Yes
139	Fuca1	17404	-0.383	-0.1544	Yes
140	Fcer1g	17495	-0.389	-0.1475	Yes
141	Csf2ra	17668	-0.405	-0.1443	Yes
142	Ctss	17707	-0.409	-0.1341	Yes
143	Nrp1	17831	-0.420	-0.1280	Yes
144	Emp1	17916	-0.428	-0.1196	Yes
145	Gypc	17984	-0.433	-0.1102	Yes
146	Galnt3	18011	-0.437	-0.0986	Yes
147	Cd37	18269	-0.463	-0.0980	Yes
148	Slpi	18639	-0.512	-0.1016	Yes
149	Gadd45g	18959	-0.565	-0.1012	Yes
150	Arg1	19029	-0.578	-0.0876	Yes
151	Hdac9	19051	-0.584	-0.0714	Yes
152	Jup	19172	-0.611	-0.0594	Yes
153	Traf1	19217	-0.622	-0.0432	Yes
154	Tnfaip3	19425	-0.702	-0.0330	Yes
155	Reln	19487	-0.725	-0.0147	Yes
156	Kcnn4	19708	-0.984	0.0032	Yes