| Dataset | CMP.CMP_Pheno.cls#Group1_versus_Group3.CMP_Pheno.cls#Group1_versus_Group3_repos |
| Phenotype | CMP_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.2950275 |
| Normalized Enrichment Score (NES) | 1.028951 |
| Nominal p-value | 0.44834712 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.994 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cse1l | 246 | 0.623 | 0.0041 | Yes |
| 2 | Hnrnpd | 334 | 0.580 | 0.0151 | Yes |
| 3 | Asf1b | 587 | 0.505 | 0.0158 | Yes |
| 4 | Racgap1 | 694 | 0.487 | 0.0234 | Yes |
| 5 | Smc3 | 709 | 0.484 | 0.0356 | Yes |
| 6 | Ipo7 | 753 | 0.476 | 0.0461 | Yes |
| 7 | Rbbp7 | 799 | 0.468 | 0.0563 | Yes |
| 8 | Dnmt1 | 865 | 0.460 | 0.0653 | Yes |
| 9 | Nup107 | 896 | 0.454 | 0.0759 | Yes |
| 10 | Brca1 | 1039 | 0.430 | 0.0801 | Yes |
| 11 | Mcm4 | 1041 | 0.430 | 0.0916 | Yes |
| 12 | Anp32e | 1196 | 0.408 | 0.0946 | Yes |
| 13 | Lmnb1 | 1223 | 0.406 | 0.1041 | Yes |
| 14 | Ncapd2 | 1270 | 0.400 | 0.1125 | Yes |
| 15 | Bub1b | 1326 | 0.395 | 0.1202 | Yes |
| 16 | Srsf1 | 1447 | 0.377 | 0.1242 | Yes |
| 17 | Ilf3 | 1484 | 0.374 | 0.1323 | Yes |
| 18 | Cnot9 | 1595 | 0.363 | 0.1364 | Yes |
| 19 | Zw10 | 1602 | 0.363 | 0.1458 | Yes |
| 20 | Brms1l | 1637 | 0.360 | 0.1537 | Yes |
| 21 | Xpo1 | 1646 | 0.359 | 0.1629 | Yes |
| 22 | Mlh1 | 1932 | 0.335 | 0.1573 | Yes |
| 23 | Mcm2 | 2040 | 0.327 | 0.1605 | Yes |
| 24 | Atad2 | 2087 | 0.324 | 0.1669 | Yes |
| 25 | Mybl2 | 2096 | 0.323 | 0.1751 | Yes |
| 26 | Espl1 | 2274 | 0.310 | 0.1744 | Yes |
| 27 | Exosc8 | 2277 | 0.310 | 0.1826 | Yes |
| 28 | Lbr | 2278 | 0.310 | 0.1908 | Yes |
| 29 | Dck | 2303 | 0.308 | 0.1979 | Yes |
| 30 | Smc1a | 2366 | 0.305 | 0.2028 | Yes |
| 31 | Nolc1 | 2390 | 0.303 | 0.2098 | Yes |
| 32 | Slbp | 2486 | 0.297 | 0.2128 | Yes |
| 33 | Cdca8 | 2619 | 0.289 | 0.2138 | Yes |
| 34 | Wee1 | 3001 | 0.263 | 0.2014 | Yes |
| 35 | Mcm7 | 3065 | 0.259 | 0.2051 | Yes |
| 36 | Dlgap5 | 3067 | 0.259 | 0.2120 | Yes |
| 37 | Rad21 | 3231 | 0.248 | 0.2103 | Yes |
| 38 | Melk | 3234 | 0.248 | 0.2168 | Yes |
| 39 | Pole | 3272 | 0.246 | 0.2215 | Yes |
| 40 | Msh2 | 3381 | 0.240 | 0.2224 | Yes |
| 41 | Spag5 | 3399 | 0.238 | 0.2279 | Yes |
| 42 | Syncrip | 3410 | 0.238 | 0.2337 | Yes |
| 43 | Cit | 3588 | 0.229 | 0.2308 | Yes |
| 44 | Prkdc | 3870 | 0.213 | 0.2221 | Yes |
| 45 | Rad51c | 3874 | 0.213 | 0.2277 | Yes |
| 46 | Mre11a | 3891 | 0.212 | 0.2325 | Yes |
| 47 | Pold3 | 3967 | 0.209 | 0.2343 | Yes |
| 48 | Hells | 4018 | 0.206 | 0.2373 | Yes |
| 49 | Cks2 | 4030 | 0.205 | 0.2422 | Yes |
| 50 | Prps1 | 4122 | 0.202 | 0.2429 | Yes |
| 51 | Nasp | 4135 | 0.201 | 0.2477 | Yes |
| 52 | Nbn | 4154 | 0.200 | 0.2521 | Yes |
| 53 | Kif4 | 4168 | 0.199 | 0.2568 | Yes |
| 54 | Tubb5 | 4188 | 0.198 | 0.2611 | Yes |
| 55 | Mcm3 | 4211 | 0.197 | 0.2652 | Yes |
| 56 | Mcm6 | 4469 | 0.184 | 0.2570 | Yes |
| 57 | Top2a | 4492 | 0.183 | 0.2608 | Yes |
| 58 | Lig1 | 4535 | 0.181 | 0.2635 | Yes |
| 59 | Nap1l1 | 4536 | 0.181 | 0.2684 | Yes |
| 60 | Tipin | 4539 | 0.181 | 0.2731 | Yes |
| 61 | Pnn | 4692 | 0.175 | 0.2700 | Yes |
| 62 | Gspt1 | 4704 | 0.175 | 0.2741 | Yes |
| 63 | Tra2b | 4710 | 0.174 | 0.2785 | Yes |
| 64 | Ubr7 | 4757 | 0.172 | 0.2808 | Yes |
| 65 | Rad1 | 4793 | 0.171 | 0.2836 | Yes |
| 66 | Cdc25b | 4839 | 0.168 | 0.2858 | Yes |
| 67 | Mcm5 | 4853 | 0.167 | 0.2896 | Yes |
| 68 | Pola2 | 4868 | 0.167 | 0.2933 | Yes |
| 69 | Smc6 | 4921 | 0.164 | 0.2950 | Yes |
| 70 | Cdkn2a | 5106 | 0.156 | 0.2898 | No |
| 71 | Rfc1 | 5133 | 0.155 | 0.2926 | No |
| 72 | Mki67 | 5258 | 0.149 | 0.2902 | No |
| 73 | Cenpe | 5418 | 0.140 | 0.2859 | No |
| 74 | Cdkn1b | 5586 | 0.134 | 0.2809 | No |
| 75 | H2az1 | 5856 | 0.124 | 0.2705 | No |
| 76 | Aurkb | 5913 | 0.122 | 0.2709 | No |
| 77 | Ctcf | 6003 | 0.118 | 0.2695 | No |
| 78 | Pole4 | 6046 | 0.117 | 0.2705 | No |
| 79 | Pa2g4 | 6053 | 0.117 | 0.2733 | No |
| 80 | Tbrg4 | 6089 | 0.115 | 0.2746 | No |
| 81 | Rad50 | 6096 | 0.115 | 0.2774 | No |
| 82 | Mad2l1 | 6240 | 0.112 | 0.2731 | No |
| 83 | Suv39h1 | 6276 | 0.111 | 0.2742 | No |
| 84 | Hus1 | 6319 | 0.109 | 0.2750 | No |
| 85 | Ube2s | 6362 | 0.107 | 0.2757 | No |
| 86 | Depdc1a | 6377 | 0.106 | 0.2778 | No |
| 87 | Pds5b | 6423 | 0.104 | 0.2783 | No |
| 88 | Cdc25a | 6429 | 0.104 | 0.2808 | No |
| 89 | Nup205 | 6475 | 0.102 | 0.2813 | No |
| 90 | Cbx5 | 6491 | 0.101 | 0.2832 | No |
| 91 | Nup153 | 6639 | 0.096 | 0.2783 | No |
| 92 | Plk1 | 6670 | 0.095 | 0.2793 | No |
| 93 | Ezh2 | 6728 | 0.093 | 0.2788 | No |
| 94 | Eif2s1 | 6767 | 0.091 | 0.2793 | No |
| 95 | Eed | 6843 | 0.089 | 0.2779 | No |
| 96 | Rpa1 | 6906 | 0.086 | 0.2770 | No |
| 97 | Tfrc | 6994 | 0.083 | 0.2748 | No |
| 98 | Psip1 | 7125 | 0.079 | 0.2703 | No |
| 99 | Tmpo | 7143 | 0.078 | 0.2715 | No |
| 100 | Pcna | 7218 | 0.075 | 0.2697 | No |
| 101 | Ccp110 | 7291 | 0.072 | 0.2680 | No |
| 102 | Hmmr | 7300 | 0.072 | 0.2695 | No |
| 103 | Dut | 7305 | 0.072 | 0.2712 | No |
| 104 | E2f8 | 7330 | 0.071 | 0.2718 | No |
| 105 | Stag1 | 7483 | 0.064 | 0.2658 | No |
| 106 | Rrm2 | 7496 | 0.064 | 0.2669 | No |
| 107 | Luc7l3 | 7625 | 0.059 | 0.2619 | No |
| 108 | Trip13 | 7701 | 0.056 | 0.2596 | No |
| 109 | Bard1 | 7866 | 0.051 | 0.2526 | No |
| 110 | Plk4 | 7922 | 0.050 | 0.2511 | No |
| 111 | Gins1 | 7980 | 0.048 | 0.2495 | No |
| 112 | Phf5a | 8004 | 0.047 | 0.2496 | No |
| 113 | Lsm8 | 8068 | 0.044 | 0.2475 | No |
| 114 | Rad51ap1 | 8124 | 0.042 | 0.2458 | No |
| 115 | Ranbp1 | 8151 | 0.042 | 0.2456 | No |
| 116 | Mms22l | 8215 | 0.039 | 0.2435 | No |
| 117 | Srsf2 | 8229 | 0.038 | 0.2438 | No |
| 118 | Tubg1 | 8242 | 0.038 | 0.2442 | No |
| 119 | Nudt21 | 8517 | 0.028 | 0.2310 | No |
| 120 | Kif22 | 8623 | 0.025 | 0.2263 | No |
| 121 | Wdr90 | 8776 | 0.019 | 0.2190 | No |
| 122 | Smc4 | 8912 | 0.014 | 0.2125 | No |
| 123 | Rpa2 | 8951 | 0.012 | 0.2109 | No |
| 124 | Pold1 | 9155 | 0.005 | 0.2006 | No |
| 125 | Xrcc6 | 9244 | 0.002 | 0.1962 | No |
| 126 | Shmt1 | 9255 | 0.001 | 0.1957 | No |
| 127 | Psmc3ip | 9362 | -0.001 | 0.1903 | No |
| 128 | Usp1 | 9467 | -0.004 | 0.1851 | No |
| 129 | Kif18b | 9590 | -0.008 | 0.1791 | No |
| 130 | Orc6 | 9611 | -0.009 | 0.1783 | No |
| 131 | Hmgb2 | 9913 | -0.021 | 0.1635 | No |
| 132 | Dek | 9956 | -0.023 | 0.1619 | No |
| 133 | Kif2c | 10033 | -0.025 | 0.1587 | No |
| 134 | Pttg1 | 10198 | -0.031 | 0.1512 | No |
| 135 | Timeless | 10307 | -0.036 | 0.1466 | No |
| 136 | Chek2 | 10308 | -0.036 | 0.1476 | No |
| 137 | Prim2 | 10389 | -0.039 | 0.1445 | No |
| 138 | Chek1 | 10510 | -0.043 | 0.1395 | No |
| 139 | Spc24 | 10609 | -0.046 | 0.1358 | No |
| 140 | Donson | 10837 | -0.054 | 0.1256 | No |
| 141 | Asf1a | 10862 | -0.055 | 0.1259 | No |
| 142 | Cdc20 | 10973 | -0.058 | 0.1218 | No |
| 143 | Birc5 | 11308 | -0.069 | 0.1066 | No |
| 144 | Ppp1r8 | 11318 | -0.069 | 0.1080 | No |
| 145 | Rfc3 | 11362 | -0.071 | 0.1077 | No |
| 146 | Paics | 11401 | -0.073 | 0.1077 | No |
| 147 | Ssrp1 | 11421 | -0.073 | 0.1087 | No |
| 148 | Trp53 | 11445 | -0.075 | 0.1095 | No |
| 149 | Diaph3 | 11458 | -0.076 | 0.1109 | No |
| 150 | Nop56 | 11517 | -0.078 | 0.1100 | No |
| 151 | Cks1b | 11823 | -0.090 | 0.0968 | No |
| 152 | Mxd3 | 11826 | -0.090 | 0.0991 | No |
| 153 | Orc2 | 11840 | -0.090 | 0.1009 | No |
| 154 | Tacc3 | 11972 | -0.097 | 0.0968 | No |
| 155 | Pms2 | 12092 | -0.102 | 0.0934 | No |
| 156 | Cdk1 | 12127 | -0.103 | 0.0944 | No |
| 157 | Cdkn1a | 12166 | -0.105 | 0.0953 | No |
| 158 | Jpt1 | 12479 | -0.117 | 0.0825 | No |
| 159 | Ppm1d | 12549 | -0.120 | 0.0822 | No |
| 160 | Cenpm | 12811 | -0.131 | 0.0723 | No |
| 161 | Ing3 | 12814 | -0.131 | 0.0757 | No |
| 162 | Pan2 | 12927 | -0.135 | 0.0736 | No |
| 163 | Dctpp1 | 13001 | -0.138 | 0.0736 | No |
| 164 | Ccnb2 | 13085 | -0.139 | 0.0730 | No |
| 165 | Cdkn3 | 13276 | -0.148 | 0.0673 | No |
| 166 | H2ax | 13383 | -0.153 | 0.0660 | No |
| 167 | Lyar | 13400 | -0.153 | 0.0692 | No |
| 168 | Brca2 | 13601 | -0.162 | 0.0634 | No |
| 169 | Pop7 | 13754 | -0.169 | 0.0601 | No |
| 170 | Pold2 | 13861 | -0.174 | 0.0593 | No |
| 171 | Hmga1b | 14075 | -0.184 | 0.0534 | No |
| 172 | Ccne1 | 14079 | -0.184 | 0.0581 | No |
| 173 | Aurka | 14234 | -0.193 | 0.0554 | No |
| 174 | Tk1 | 14539 | -0.208 | 0.0455 | No |
| 175 | Rnaseh2a | 14721 | -0.217 | 0.0420 | No |
| 176 | Ak2 | 14819 | -0.222 | 0.0430 | No |
| 177 | Dclre1b | 14823 | -0.222 | 0.0488 | No |
| 178 | Myc | 14831 | -0.223 | 0.0544 | No |
| 179 | Tcf19 | 15020 | -0.231 | 0.0510 | No |
| 180 | Ube2t | 15097 | -0.235 | 0.0534 | No |
| 181 | Rfc2 | 15161 | -0.238 | 0.0565 | No |
| 182 | Mthfd2 | 15165 | -0.238 | 0.0627 | No |
| 183 | Stmn1 | 15780 | -0.269 | 0.0385 | No |
| 184 | Cdkn2c | 15899 | -0.279 | 0.0400 | No |
| 185 | Ddx39a | 16175 | -0.296 | 0.0338 | No |
| 186 | Spc25 | 16469 | -0.314 | 0.0273 | No |
| 187 | Cdk4 | 16570 | -0.321 | 0.0307 | No |
| 188 | Ung | 16734 | -0.332 | 0.0313 | No |
| 189 | Ran | 16823 | -0.339 | 0.0358 | No |
| 190 | Gins3 | 17125 | -0.360 | 0.0301 | No |
| 191 | Gins4 | 17135 | -0.361 | 0.0393 | No |
| 192 | Hmgb3 | 17401 | -0.383 | 0.0360 | No |
| 193 | Rpa3 | 17608 | -0.400 | 0.0361 | No |
| 194 | Cdca3 | 17694 | -0.408 | 0.0427 | No |
| 195 | Snrpb | 18317 | -0.468 | 0.0234 | No |
| 196 | Dscc1 | 19137 | -0.603 | -0.0023 | No |
| 197 | Prdx4 | 19228 | -0.628 | 0.0099 | No |
| 198 | Nme1 | 19344 | -0.667 | 0.0218 | No |

