| Dataset | CMP.Basophil_Pheno.cls #Group1_versus_Group2.Basophil_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | Basophil_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | -0.41232118 |
| Normalized Enrichment Score (NES) | -1.5894132 |
| Nominal p-value | 0.092369474 |
| FDR q-value | 0.16622326 |
| FWER p-Value | 0.254 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ppp1r15a | 108 | 0.773 | 0.0134 | No |
| 2 | Mthfd2l | 858 | 0.505 | -0.0125 | No |
| 3 | Fdxr | 1795 | 0.387 | -0.0508 | No |
| 4 | G6pdx | 1965 | 0.372 | -0.0503 | No |
| 5 | Ccng1 | 2057 | 0.364 | -0.0461 | No |
| 6 | Slc37a4 | 2109 | 0.359 | -0.0399 | No |
| 7 | Slc7a11 | 2299 | 0.342 | -0.0412 | No |
| 8 | Niban1 | 2701 | 0.314 | -0.0539 | No |
| 9 | Mllt11 | 2985 | 0.297 | -0.0611 | No |
| 10 | Plod2 | 3011 | 0.295 | -0.0552 | No |
| 11 | Rit1 | 3340 | 0.273 | -0.0653 | No |
| 12 | Gbe1 | 3619 | 0.258 | -0.0731 | No |
| 13 | Slc2a3 | 4334 | 0.222 | -0.1042 | No |
| 14 | Gtf2h1 | 4348 | 0.221 | -0.0994 | No |
| 15 | Cops5 | 4454 | 0.216 | -0.0995 | No |
| 16 | Idi1 | 4623 | 0.208 | -0.1030 | No |
| 17 | Qdpr | 4824 | 0.197 | -0.1084 | No |
| 18 | Tmem97 | 5174 | 0.180 | -0.1218 | No |
| 19 | Psat1 | 5302 | 0.174 | -0.1240 | No |
| 20 | Dapp1 | 5544 | 0.163 | -0.1324 | No |
| 21 | Itgb2 | 5968 | 0.144 | -0.1504 | No |
| 22 | Btg2 | 5970 | 0.144 | -0.1470 | No |
| 23 | Ak4 | 6169 | 0.135 | -0.1538 | No |
| 24 | Psmg1 | 6445 | 0.124 | -0.1648 | No |
| 25 | Eef1e1 | 6527 | 0.120 | -0.1659 | No |
| 26 | Glrx | 6572 | 0.119 | -0.1653 | No |
| 27 | Cfp | 6766 | 0.112 | -0.1724 | No |
| 28 | Cd9 | 7061 | 0.099 | -0.1850 | No |
| 29 | Mcm4 | 7113 | 0.097 | -0.1852 | No |
| 30 | Sec11a | 7226 | 0.093 | -0.1886 | No |
| 31 | Sqstm1 | 7401 | 0.086 | -0.1954 | No |
| 32 | Gclc | 7404 | 0.086 | -0.1934 | No |
| 33 | Slc2a1 | 7412 | 0.086 | -0.1917 | No |
| 34 | Elovl5 | 7432 | 0.085 | -0.1905 | No |
| 35 | Tubg1 | 7451 | 0.084 | -0.1894 | No |
| 36 | Nampt | 7468 | 0.083 | -0.1882 | No |
| 37 | Edem1 | 7530 | 0.081 | -0.1893 | No |
| 38 | Slc1a5 | 7536 | 0.080 | -0.1876 | No |
| 39 | Fgl2 | 7568 | 0.079 | -0.1873 | No |
| 40 | Gsk3b | 7934 | 0.066 | -0.2043 | No |
| 41 | Idh1 | 7936 | 0.066 | -0.2027 | No |
| 42 | Ldlr | 7996 | 0.064 | -0.2042 | No |
| 43 | Adipor2 | 8101 | 0.060 | -0.2080 | No |
| 44 | Eno1b | 8219 | 0.056 | -0.2126 | No |
| 45 | Gga2 | 8223 | 0.056 | -0.2114 | No |
| 46 | Nfil3 | 8248 | 0.055 | -0.2113 | No |
| 47 | Atp2a2 | 8257 | 0.055 | -0.2104 | No |
| 48 | Ifrd1 | 8336 | 0.052 | -0.2131 | No |
| 49 | Pgm1 | 8363 | 0.051 | -0.2132 | No |
| 50 | Tbk1 | 8445 | 0.047 | -0.2162 | No |
| 51 | Pdk1 | 8450 | 0.047 | -0.2152 | No |
| 52 | Dhcr7 | 8625 | 0.041 | -0.2231 | No |
| 53 | Pik3r3 | 8749 | 0.037 | -0.2285 | No |
| 54 | Nfkbib | 8809 | 0.035 | -0.2306 | No |
| 55 | Acly | 8845 | 0.033 | -0.2316 | No |
| 56 | Add3 | 8870 | 0.032 | -0.2320 | No |
| 57 | Ufm1 | 9175 | 0.022 | -0.2470 | No |
| 58 | Pgk1 | 9211 | 0.020 | -0.2483 | No |
| 59 | Nufip1 | 9320 | 0.017 | -0.2534 | No |
| 60 | Me1 | 9355 | 0.016 | -0.2548 | No |
| 61 | Hmbs | 9383 | 0.015 | -0.2558 | No |
| 62 | Rrp9 | 9405 | 0.014 | -0.2565 | No |
| 63 | Psmc6 | 9417 | 0.013 | -0.2568 | No |
| 64 | Mcm2 | 9511 | 0.010 | -0.2613 | No |
| 65 | Hk2 | 9546 | 0.008 | -0.2628 | No |
| 66 | Cxcr4 | 9727 | 0.002 | -0.2719 | No |
| 67 | Psme3 | 9851 | -0.001 | -0.2782 | No |
| 68 | Immt | 9973 | -0.005 | -0.2842 | No |
| 69 | Tuba4a | 10117 | -0.011 | -0.2913 | No |
| 70 | Lta4h | 10412 | -0.021 | -0.3058 | No |
| 71 | Gla | 10435 | -0.023 | -0.3063 | No |
| 72 | Serp1 | 10518 | -0.025 | -0.3099 | No |
| 73 | Wars1 | 10862 | -0.038 | -0.3265 | No |
| 74 | Asns | 10927 | -0.041 | -0.3288 | No |
| 75 | Tcea1 | 11042 | -0.045 | -0.3335 | No |
| 76 | Pitpnb | 11053 | -0.045 | -0.3329 | No |
| 77 | Insig1 | 11208 | -0.051 | -0.3395 | No |
| 78 | Aldoa | 11441 | -0.060 | -0.3499 | No |
| 79 | Atp6v1d | 11504 | -0.062 | -0.3515 | No |
| 80 | Psma4 | 11505 | -0.062 | -0.3500 | No |
| 81 | Fkbp2 | 11623 | -0.065 | -0.3544 | No |
| 82 | Calr | 11628 | -0.065 | -0.3530 | No |
| 83 | Ldha | 11664 | -0.067 | -0.3532 | No |
| 84 | Psmd13 | 11758 | -0.071 | -0.3562 | No |
| 85 | Gmps | 11789 | -0.072 | -0.3559 | No |
| 86 | Slc1a4 | 11840 | -0.073 | -0.3567 | No |
| 87 | M6pr | 11895 | -0.076 | -0.3576 | No |
| 88 | Uso1 | 11923 | -0.077 | -0.3571 | No |
| 89 | Arpc5l | 12083 | -0.084 | -0.3632 | No |
| 90 | Tomm40 | 12123 | -0.085 | -0.3631 | No |
| 91 | Bcat1 | 12224 | -0.089 | -0.3660 | No |
| 92 | Rdh11 | 12245 | -0.090 | -0.3648 | No |
| 93 | Sc5d | 12349 | -0.094 | -0.3678 | No |
| 94 | Sla | 12505 | -0.099 | -0.3733 | No |
| 95 | Stard4 | 12511 | -0.099 | -0.3711 | No |
| 96 | Psmc2 | 12593 | -0.103 | -0.3727 | No |
| 97 | Ykt6 | 13011 | -0.120 | -0.3911 | No |
| 98 | Pno1 | 13079 | -0.124 | -0.3915 | No |
| 99 | Phgdh | 13136 | -0.126 | -0.3912 | No |
| 100 | Tm7sf2 | 13334 | -0.135 | -0.3980 | No |
| 101 | Gsr | 13445 | -0.140 | -0.4002 | No |
| 102 | Actr2 | 13589 | -0.144 | -0.4040 | No |
| 103 | Plk1 | 13702 | -0.149 | -0.4060 | No |
| 104 | Rab1a | 13786 | -0.153 | -0.4065 | No |
| 105 | Slc7a5 | 13801 | -0.154 | -0.4035 | No |
| 106 | Elovl6 | 13804 | -0.154 | -0.3998 | No |
| 107 | Sqle | 13898 | -0.158 | -0.4007 | No |
| 108 | Psmd14 | 14001 | -0.162 | -0.4019 | No |
| 109 | Rpa1 | 14112 | -0.167 | -0.4035 | No |
| 110 | Bub1 | 14286 | -0.174 | -0.4081 | Yes |
| 111 | Gpi1 | 14314 | -0.175 | -0.4051 | Yes |
| 112 | Dhcr24 | 14326 | -0.176 | -0.4014 | Yes |
| 113 | Ube2d3 | 14366 | -0.177 | -0.3991 | Yes |
| 114 | Egln3 | 14380 | -0.178 | -0.3954 | Yes |
| 115 | Nup205 | 14413 | -0.179 | -0.3926 | Yes |
| 116 | Hmgcr | 14606 | -0.188 | -0.3978 | Yes |
| 117 | Hspa4 | 14695 | -0.191 | -0.3976 | Yes |
| 118 | Psmc4 | 14732 | -0.193 | -0.3948 | Yes |
| 119 | Ifi30 | 14771 | -0.195 | -0.3919 | Yes |
| 120 | Nfyc | 14822 | -0.197 | -0.3897 | Yes |
| 121 | Hspa5 | 14873 | -0.199 | -0.3874 | Yes |
| 122 | Actr3 | 14894 | -0.201 | -0.3835 | Yes |
| 123 | Ssr1 | 14921 | -0.202 | -0.3799 | Yes |
| 124 | Dhfr | 14953 | -0.204 | -0.3765 | Yes |
| 125 | Cdkn1a | 15001 | -0.206 | -0.3738 | Yes |
| 126 | P4ha1 | 15018 | -0.207 | -0.3696 | Yes |
| 127 | Ung | 15040 | -0.208 | -0.3656 | Yes |
| 128 | Lgmn | 15100 | -0.210 | -0.3634 | Yes |
| 129 | Ebp | 15162 | -0.213 | -0.3613 | Yes |
| 130 | Ddit3 | 15163 | -0.214 | -0.3561 | Yes |
| 131 | Sdf2l1 | 15235 | -0.217 | -0.3544 | Yes |
| 132 | Psmd12 | 15268 | -0.219 | -0.3507 | Yes |
| 133 | Cyb5b | 15357 | -0.224 | -0.3497 | Yes |
| 134 | Tes | 15437 | -0.228 | -0.3482 | Yes |
| 135 | Cct6a | 15438 | -0.228 | -0.3426 | Yes |
| 136 | Uchl5 | 15468 | -0.230 | -0.3384 | Yes |
| 137 | Ero1a | 15581 | -0.236 | -0.3384 | Yes |
| 138 | Cth | 15598 | -0.237 | -0.3334 | Yes |
| 139 | Fads2 | 15605 | -0.237 | -0.3279 | Yes |
| 140 | Srd5a1 | 15608 | -0.237 | -0.3222 | Yes |
| 141 | Hsp90b1 | 15650 | -0.240 | -0.3184 | Yes |
| 142 | Slc6a6 | 15654 | -0.240 | -0.3127 | Yes |
| 143 | Stip1 | 15660 | -0.240 | -0.3071 | Yes |
| 144 | Skap2 | 15757 | -0.246 | -0.3059 | Yes |
| 145 | Ctsc | 15835 | -0.250 | -0.3038 | Yes |
| 146 | Ddx39a | 15897 | -0.253 | -0.3007 | Yes |
| 147 | Canx | 15900 | -0.253 | -0.2946 | Yes |
| 148 | Map2k3 | 16065 | -0.262 | -0.2965 | Yes |
| 149 | Cdc25a | 16110 | -0.265 | -0.2923 | Yes |
| 150 | Prdx1 | 16146 | -0.266 | -0.2876 | Yes |
| 151 | Ddit4 | 16165 | -0.267 | -0.2819 | Yes |
| 152 | Psmb5 | 16171 | -0.267 | -0.2756 | Yes |
| 153 | Rpn1 | 16235 | -0.271 | -0.2722 | Yes |
| 154 | Acaca | 16333 | -0.277 | -0.2704 | Yes |
| 155 | Pfkl | 16832 | -0.309 | -0.2883 | Yes |
| 156 | Abcf2 | 16951 | -0.318 | -0.2865 | Yes |
| 157 | Sord | 17008 | -0.321 | -0.2815 | Yes |
| 158 | Nupr1 | 17104 | -0.330 | -0.2783 | Yes |
| 159 | Got1 | 17142 | -0.333 | -0.2720 | Yes |
| 160 | Ccnf | 17234 | -0.342 | -0.2683 | Yes |
| 161 | Pdap1 | 17287 | -0.344 | -0.2626 | Yes |
| 162 | Ppa1 | 17300 | -0.345 | -0.2548 | Yes |
| 163 | Cyp51 | 17323 | -0.347 | -0.2474 | Yes |
| 164 | Fads1 | 17345 | -0.348 | -0.2399 | Yes |
| 165 | Polr3g | 17606 | -0.368 | -0.2442 | Yes |
| 166 | Eif2s2 | 17687 | -0.374 | -0.2391 | Yes |
| 167 | Psma3 | 17809 | -0.385 | -0.2359 | Yes |
| 168 | Trib3 | 17822 | -0.386 | -0.2270 | Yes |
| 169 | Etf1 | 17897 | -0.394 | -0.2212 | Yes |
| 170 | Nmt1 | 17937 | -0.397 | -0.2134 | Yes |
| 171 | Hmgcs1 | 17971 | -0.400 | -0.2053 | Yes |
| 172 | Tpi1 | 17997 | -0.402 | -0.1967 | Yes |
| 173 | Hspa9 | 18207 | -0.426 | -0.1970 | Yes |
| 174 | Mthfd2 | 18325 | -0.438 | -0.1923 | Yes |
| 175 | Coro1a | 18405 | -0.448 | -0.1853 | Yes |
| 176 | Ppia | 18564 | -0.466 | -0.1820 | Yes |
| 177 | Txnrd1 | 18593 | -0.468 | -0.1719 | Yes |
| 178 | Rrm2 | 18606 | -0.470 | -0.1610 | Yes |
| 179 | Hspd1 | 18789 | -0.497 | -0.1582 | Yes |
| 180 | Shmt2 | 18859 | -0.507 | -0.1493 | Yes |
| 181 | Psph | 18931 | -0.516 | -0.1403 | Yes |
| 182 | Hspe1 | 19060 | -0.544 | -0.1335 | Yes |
| 183 | Xbp1 | 19134 | -0.566 | -0.1234 | Yes |
| 184 | Tfrc | 19206 | -0.580 | -0.1128 | Yes |
| 185 | Serpinh1 | 19290 | -0.603 | -0.1023 | Yes |
| 186 | Sytl2 | 19333 | -0.618 | -0.0893 | Yes |
| 187 | Pnp | 19423 | -0.649 | -0.0780 | Yes |
| 188 | Acsl3 | 19435 | -0.652 | -0.0626 | Yes |
| 189 | Cacybp | 19495 | -0.676 | -0.0490 | Yes |
| 190 | Aurka | 19579 | -0.719 | -0.0357 | Yes |
| 191 | Vldlr | 19669 | -0.812 | -0.0203 | Yes |
| 192 | Bhlhe40 | 19752 | -1.041 | 0.0010 | Yes |

