Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | CLP.Basophil_Pheno.cls #Group6_versus_Group8.Basophil_Pheno.cls #Group6_versus_Group8_repos |
| Phenotype | Basophil_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_IL6_JAK_STAT3_SIGNALING |
| Enrichment Score (ES) | -0.3354824 |
| Normalized Enrichment Score (NES) | -1.2533072 |
| Nominal p-value | 0.17159763 |
| FDR q-value | 0.38033715 |
| FWER p-Value | 0.846 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Il15ra | 537 | 0.636 | 0.0168 | No |
| 2 | Il13ra1 | 2297 | 0.394 | -0.0504 | No |
| 3 | Cd9 | 2857 | 0.330 | -0.0569 | No |
| 4 | Cd44 | 3109 | 0.309 | -0.0482 | No |
| 5 | Cxcl10 | 3597 | 0.276 | -0.0547 | No |
| 6 | Tnfrsf1b | 3774 | 0.268 | -0.0448 | No |
| 7 | Csf1 | 3908 | 0.259 | -0.0333 | No |
| 8 | Stam2 | 4027 | 0.252 | -0.0215 | No |
| 9 | Ccr1 | 4308 | 0.246 | -0.0189 | No |
| 10 | Ptpn1 | 5427 | 0.190 | -0.0660 | No |
| 11 | Ptpn2 | 5807 | 0.169 | -0.0744 | No |
| 12 | Il18r1 | 5994 | 0.159 | -0.0730 | No |
| 13 | Hax1 | 6491 | 0.133 | -0.0903 | No |
| 14 | Itgb3 | 6517 | 0.132 | -0.0821 | No |
| 15 | Tnf | 6627 | 0.127 | -0.0788 | No |
| 16 | Pdgfc | 6646 | 0.126 | -0.0707 | No |
| 17 | Cd36 | 6730 | 0.122 | -0.0663 | No |
| 18 | Ptpn11 | 7280 | 0.095 | -0.0894 | No |
| 19 | Il17rb | 7396 | 0.090 | -0.0891 | No |
| 20 | Ifnar1 | 7658 | 0.077 | -0.0977 | No |
| 21 | Cd38 | 7780 | 0.072 | -0.0991 | No |
| 22 | Jun | 8059 | 0.058 | -0.1100 | No |
| 23 | Il6st | 8601 | 0.032 | -0.1372 | No |
| 24 | Dntt | 8873 | 0.021 | -0.1504 | No |
| 25 | Itga4 | 9073 | 0.012 | -0.1604 | No |
| 26 | Il7 | 9227 | 0.006 | -0.1682 | No |
| 27 | Hmox1 | 9361 | 0.000 | -0.1755 | No |
| 28 | Bak1 | 9718 | -0.000 | -0.1949 | No |
| 29 | Crlf2 | 10157 | -0.018 | -0.2175 | No |
| 30 | Tyk2 | 10181 | -0.019 | -0.2173 | No |
| 31 | Il17ra | 10186 | -0.019 | -0.2161 | No |
| 32 | Il10rb | 10193 | -0.020 | -0.2150 | No |
| 33 | Tgfb1 | 10339 | -0.026 | -0.2211 | No |
| 34 | Map3k8 | 10394 | -0.028 | -0.2220 | No |
| 35 | Ltb | 10609 | -0.038 | -0.2309 | No |
| 36 | Acvrl1 | 11037 | -0.056 | -0.2501 | No |
| 37 | Tnfrsf21 | 11132 | -0.059 | -0.2510 | No |
| 38 | Il1r2 | 11196 | -0.061 | -0.2500 | No |
| 39 | Il2rg | 11624 | -0.078 | -0.2676 | No |
| 40 | Il1r1 | 12521 | -0.119 | -0.3078 | No |
| 41 | Cbl | 12697 | -0.127 | -0.3081 | No |
| 42 | Il4ra | 12735 | -0.128 | -0.3009 | No |
| 43 | Grb2 | 12915 | -0.136 | -0.3007 | No |
| 44 | Pim1 | 13052 | -0.144 | -0.2977 | No |
| 45 | Pik3r5 | 13192 | -0.151 | -0.2943 | No |
| 46 | Irf1 | 13359 | -0.160 | -0.2917 | No |
| 47 | Pf4 | 13564 | -0.170 | -0.2905 | No |
| 48 | Acvr1b | 13591 | -0.171 | -0.2795 | No |
| 49 | Ltbr | 13869 | -0.186 | -0.2811 | No |
| 50 | Myd88 | 14126 | -0.200 | -0.2805 | No |
| 51 | Il3ra | 14440 | -0.218 | -0.2818 | No |
| 52 | Stat1 | 14705 | -0.234 | -0.2792 | No |
| 53 | Stat2 | 15738 | -0.298 | -0.3139 | Yes |
| 54 | Tlr2 | 15803 | -0.302 | -0.2954 | Yes |
| 55 | Tnfrsf12a | 15846 | -0.305 | -0.2755 | Yes |
| 56 | Fas | 16074 | -0.317 | -0.2649 | Yes |
| 57 | Socs1 | 16241 | -0.331 | -0.2499 | Yes |
| 58 | Tnfrsf1a | 16501 | -0.350 | -0.2387 | Yes |
| 59 | Socs3 | 17142 | -0.414 | -0.2435 | Yes |
| 60 | Csf3r | 17173 | -0.418 | -0.2148 | Yes |
| 61 | Stat3 | 17477 | -0.463 | -0.1977 | Yes |
| 62 | Ifngr2 | 17482 | -0.463 | -0.1643 | Yes |
| 63 | Ifngr1 | 17508 | -0.470 | -0.1316 | Yes |
| 64 | Csf2ra | 17906 | -0.550 | -0.1133 | Yes |
| 65 | Il12rb1 | 17920 | -0.552 | -0.0740 | Yes |
| 66 | Ebi3 | 18199 | -0.664 | -0.0410 | Yes |
| 67 | Irf9 | 18268 | -0.721 | 0.0076 | Yes |
