| Dataset | CLP.Basophil_Pheno.cls #Group3_versus_Group4.Basophil_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | Basophil_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_HEME_METABOLISM |
| Enrichment Score (ES) | -0.20652111 |
| Normalized Enrichment Score (NES) | -1.0062072 |
| Nominal p-value | 0.469428 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.99 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Slc11a2 | 81 | 0.868 | 0.0191 | No |
| 2 | Marchf8 | 172 | 0.763 | 0.0349 | No |
| 3 | C3 | 325 | 0.674 | 0.0449 | No |
| 4 | Gata1 | 337 | 0.668 | 0.0624 | No |
| 5 | Atp6v0a1 | 725 | 0.545 | 0.0560 | No |
| 6 | Ranbp10 | 878 | 0.513 | 0.0616 | No |
| 7 | Rap1gap | 1095 | 0.479 | 0.0628 | No |
| 8 | Hebp1 | 1137 | 0.473 | 0.0734 | No |
| 9 | Ell2 | 1250 | 0.454 | 0.0796 | No |
| 10 | Kdm7a | 1253 | 0.453 | 0.0918 | No |
| 11 | Alas2 | 1331 | 0.445 | 0.0996 | No |
| 12 | Urod | 1412 | 0.436 | 0.1071 | No |
| 13 | Slc4a1 | 1699 | 0.399 | 0.1022 | No |
| 14 | Ezh1 | 1852 | 0.385 | 0.1044 | No |
| 15 | Daam1 | 1915 | 0.379 | 0.1112 | No |
| 16 | Glrx5 | 1935 | 0.377 | 0.1204 | No |
| 17 | Slc30a1 | 2101 | 0.364 | 0.1213 | No |
| 18 | Slc6a8 | 2271 | 0.346 | 0.1214 | No |
| 19 | Lmo2 | 2519 | 0.330 | 0.1168 | No |
| 20 | Fbxo7 | 2554 | 0.327 | 0.1238 | No |
| 21 | Dcun1d1 | 2951 | 0.298 | 0.1102 | No |
| 22 | Foxj2 | 3003 | 0.296 | 0.1154 | No |
| 23 | Add2 | 3335 | 0.275 | 0.1047 | No |
| 24 | Bpgm | 3346 | 0.274 | 0.1116 | No |
| 25 | Tmem9b | 3347 | 0.274 | 0.1191 | No |
| 26 | Btrc | 3458 | 0.267 | 0.1203 | No |
| 27 | Add1 | 3474 | 0.265 | 0.1266 | No |
| 28 | Psmd9 | 3700 | 0.251 | 0.1211 | No |
| 29 | Bnip3l | 3874 | 0.244 | 0.1182 | No |
| 30 | Nfe2l1 | 3961 | 0.238 | 0.1200 | No |
| 31 | Eif2ak1 | 4012 | 0.235 | 0.1236 | No |
| 32 | Khnyn | 4431 | 0.211 | 0.1064 | No |
| 33 | H1f0 | 4682 | 0.198 | 0.0981 | No |
| 34 | Dcaf10 | 4712 | 0.197 | 0.1019 | No |
| 35 | Sidt2 | 5013 | 0.182 | 0.0903 | No |
| 36 | Tfrc | 5017 | 0.182 | 0.0951 | No |
| 37 | Rnf19a | 5168 | 0.175 | 0.0916 | No |
| 38 | Xk | 5277 | 0.169 | 0.0903 | No |
| 39 | Usp15 | 5344 | 0.166 | 0.0912 | No |
| 40 | Tfdp2 | 5607 | 0.153 | 0.0810 | No |
| 41 | Adipor1 | 5867 | 0.143 | 0.0706 | No |
| 42 | Fbxo34 | 5879 | 0.142 | 0.0739 | No |
| 43 | Fn3k | 6028 | 0.135 | 0.0694 | No |
| 44 | Picalm | 6415 | 0.119 | 0.0515 | No |
| 45 | Nudt4 | 6432 | 0.118 | 0.0538 | No |
| 46 | Trak2 | 6444 | 0.118 | 0.0564 | No |
| 47 | Arl2bp | 6730 | 0.105 | 0.0436 | No |
| 48 | Tns1 | 6751 | 0.104 | 0.0454 | No |
| 49 | Kel | 6861 | 0.099 | 0.0421 | No |
| 50 | Bcam | 6916 | 0.097 | 0.0417 | No |
| 51 | Tspo2 | 6928 | 0.096 | 0.0437 | No |
| 52 | Klf3 | 6932 | 0.096 | 0.0462 | No |
| 53 | Aqp3 | 7072 | 0.090 | 0.0410 | No |
| 54 | Mpp1 | 7136 | 0.088 | 0.0399 | No |
| 55 | Tyr | 7150 | 0.087 | 0.0416 | No |
| 56 | Endod1 | 7238 | 0.087 | 0.0392 | No |
| 57 | Rnf123 | 7285 | 0.085 | 0.0390 | No |
| 58 | Agpat4 | 7340 | 0.083 | 0.0382 | No |
| 59 | Cat | 7365 | 0.082 | 0.0392 | No |
| 60 | Epb41 | 7527 | 0.075 | 0.0324 | No |
| 61 | Gapvd1 | 7793 | 0.065 | 0.0196 | No |
| 62 | Cdc27 | 7802 | 0.065 | 0.0209 | No |
| 63 | Pcx | 7907 | 0.061 | 0.0169 | No |
| 64 | Htatip2 | 7919 | 0.061 | 0.0179 | No |
| 65 | Nek7 | 7966 | 0.059 | 0.0170 | No |
| 66 | Mocos | 8084 | 0.055 | 0.0121 | No |
| 67 | Igsf3 | 8162 | 0.051 | 0.0092 | No |
| 68 | Bach1 | 8284 | 0.047 | 0.0038 | No |
| 69 | Nfe2 | 8375 | 0.042 | 0.0001 | No |
| 70 | Slc66a2 | 8399 | 0.041 | -0.0001 | No |
| 71 | Synj1 | 8461 | 0.038 | -0.0024 | No |
| 72 | Pigq | 8480 | 0.037 | -0.0024 | No |
| 73 | Gmps | 8488 | 0.037 | -0.0018 | No |
| 74 | Clcn3 | 8546 | 0.034 | -0.0040 | No |
| 75 | Cpox | 8565 | 0.034 | -0.0041 | No |
| 76 | Klf1 | 8731 | 0.027 | -0.0124 | No |
| 77 | Car2 | 8819 | 0.024 | -0.0165 | No |
| 78 | Ubac1 | 8842 | 0.023 | -0.0171 | No |
| 79 | Aldh6a1 | 8987 | 0.017 | -0.0245 | No |
| 80 | Epor | 8989 | 0.017 | -0.0241 | No |
| 81 | Riok3 | 9035 | 0.016 | -0.0262 | No |
| 82 | Tent5c | 9144 | 0.012 | -0.0318 | No |
| 83 | Minpp1 | 9148 | 0.011 | -0.0316 | No |
| 84 | Gclm | 9427 | 0.002 | -0.0468 | No |
| 85 | Trim58 | 9629 | -0.003 | -0.0578 | No |
| 86 | Ank1 | 9819 | -0.011 | -0.0678 | No |
| 87 | Rhd | 9821 | -0.011 | -0.0676 | No |
| 88 | Bmp2k | 9899 | -0.013 | -0.0715 | No |
| 89 | Foxo3 | 10098 | -0.020 | -0.0818 | No |
| 90 | Spta1 | 10164 | -0.022 | -0.0847 | No |
| 91 | Cir1 | 10238 | -0.025 | -0.0881 | No |
| 92 | Nr3c1 | 10278 | -0.027 | -0.0895 | No |
| 93 | Cast | 10295 | -0.027 | -0.0896 | No |
| 94 | Slc22a4 | 10383 | -0.031 | -0.0936 | No |
| 95 | Dmtn | 10461 | -0.034 | -0.0968 | No |
| 96 | Mboat2 | 10489 | -0.035 | -0.0974 | No |
| 97 | Bsg | 10728 | -0.043 | -0.1093 | No |
| 98 | Arhgef12 | 10745 | -0.044 | -0.1089 | No |
| 99 | Gypc | 10761 | -0.045 | -0.1085 | No |
| 100 | Atg4a | 10836 | -0.048 | -0.1113 | No |
| 101 | Fech | 10951 | -0.052 | -0.1162 | No |
| 102 | Hdgf | 11060 | -0.054 | -0.1206 | No |
| 103 | Tnrc6b | 11094 | -0.056 | -0.1209 | No |
| 104 | Sec14l1 | 11105 | -0.056 | -0.1199 | No |
| 105 | Ncoa4 | 11157 | -0.058 | -0.1212 | No |
| 106 | Tspan5 | 11317 | -0.064 | -0.1281 | No |
| 107 | Rbm5 | 11376 | -0.067 | -0.1295 | No |
| 108 | Lpin2 | 11491 | -0.071 | -0.1338 | No |
| 109 | Top1 | 11504 | -0.071 | -0.1326 | No |
| 110 | Aldh1l1 | 11531 | -0.072 | -0.1320 | No |
| 111 | P4ha2 | 11564 | -0.074 | -0.1318 | No |
| 112 | Prdx2 | 11614 | -0.076 | -0.1324 | No |
| 113 | Snca | 11749 | -0.081 | -0.1376 | No |
| 114 | Ppox | 12019 | -0.092 | -0.1498 | No |
| 115 | Tal1 | 12093 | -0.094 | -0.1513 | No |
| 116 | Lamp2 | 12153 | -0.097 | -0.1519 | No |
| 117 | Htra2 | 12154 | -0.097 | -0.1493 | No |
| 118 | Ypel5 | 12229 | -0.100 | -0.1506 | No |
| 119 | Slc25a38 | 12641 | -0.117 | -0.1700 | No |
| 120 | Hmbs | 12706 | -0.119 | -0.1703 | No |
| 121 | Asns | 12747 | -0.122 | -0.1691 | No |
| 122 | Acsl6 | 12754 | -0.122 | -0.1662 | No |
| 123 | Mark3 | 12791 | -0.123 | -0.1648 | No |
| 124 | Rhag | 13179 | -0.140 | -0.1822 | No |
| 125 | Fbxo9 | 13253 | -0.143 | -0.1823 | No |
| 126 | Tcea1 | 13380 | -0.149 | -0.1852 | No |
| 127 | Gclc | 13382 | -0.149 | -0.1812 | No |
| 128 | Dcaf11 | 13417 | -0.150 | -0.1790 | No |
| 129 | Sdcbp | 13624 | -0.160 | -0.1860 | No |
| 130 | Vezf1 | 13625 | -0.160 | -0.1816 | No |
| 131 | Rbm38 | 13697 | -0.164 | -0.1811 | No |
| 132 | Gde1 | 13700 | -0.164 | -0.1767 | No |
| 133 | Smox | 13870 | -0.172 | -0.1813 | No |
| 134 | Blvra | 13903 | -0.173 | -0.1784 | No |
| 135 | Rcl1 | 13962 | -0.176 | -0.1768 | No |
| 136 | Optn | 14217 | -0.190 | -0.1856 | No |
| 137 | Slc2a1 | 14292 | -0.194 | -0.1844 | No |
| 138 | Mkrn1 | 14302 | -0.194 | -0.1796 | No |
| 139 | Map2k3 | 14741 | -0.215 | -0.1978 | No |
| 140 | Lrp10 | 14822 | -0.220 | -0.1962 | No |
| 141 | Ccdc28a | 14916 | -0.226 | -0.1952 | No |
| 142 | Blvrb | 15124 | -0.235 | -0.2001 | Yes |
| 143 | Ccnd3 | 15217 | -0.241 | -0.1986 | Yes |
| 144 | Tmcc2 | 15230 | -0.242 | -0.1927 | Yes |
| 145 | Mfhas1 | 15319 | -0.248 | -0.1908 | Yes |
| 146 | Mgst3 | 15330 | -0.248 | -0.1846 | Yes |
| 147 | Uros | 15501 | -0.259 | -0.1869 | Yes |
| 148 | Btg2 | 15575 | -0.265 | -0.1838 | Yes |
| 149 | Ctsb | 15586 | -0.265 | -0.1771 | Yes |
| 150 | Nnt | 15595 | -0.266 | -0.1703 | Yes |
| 151 | Hagh | 15630 | -0.269 | -0.1649 | Yes |
| 152 | Ucp2 | 15643 | -0.270 | -0.1582 | Yes |
| 153 | Osbp2 | 15716 | -0.273 | -0.1547 | Yes |
| 154 | Epb42 | 15749 | -0.276 | -0.1490 | Yes |
| 155 | Xpo7 | 15920 | -0.288 | -0.1505 | Yes |
| 156 | Pdzk1ip1 | 15935 | -0.290 | -0.1434 | Yes |
| 157 | Mospd1 | 15938 | -0.290 | -0.1356 | Yes |
| 158 | Ctse | 16092 | -0.300 | -0.1359 | Yes |
| 159 | Ppp2r5b | 16106 | -0.301 | -0.1284 | Yes |
| 160 | Icam4 | 16226 | -0.310 | -0.1265 | Yes |
| 161 | Slc6a9 | 16262 | -0.311 | -0.1200 | Yes |
| 162 | Cdr2 | 16412 | -0.323 | -0.1194 | Yes |
| 163 | Alad | 16420 | -0.324 | -0.1110 | Yes |
| 164 | Selenbp1 | 16729 | -0.349 | -0.1184 | Yes |
| 165 | Sptb | 16866 | -0.360 | -0.1161 | Yes |
| 166 | Ctns | 17067 | -0.382 | -0.1167 | Yes |
| 167 | Narf | 17082 | -0.386 | -0.1070 | Yes |
| 168 | Abcb6 | 17131 | -0.391 | -0.0990 | Yes |
| 169 | Kat2b | 17138 | -0.392 | -0.0887 | Yes |
| 170 | Acp5 | 17201 | -0.399 | -0.0812 | Yes |
| 171 | Mxi1 | 17328 | -0.415 | -0.0769 | Yes |
| 172 | Marchf2 | 17330 | -0.415 | -0.0657 | Yes |
| 173 | Slc10a3 | 17403 | -0.424 | -0.0581 | Yes |
| 174 | Pgls | 17442 | -0.431 | -0.0485 | Yes |
| 175 | Rad23a | 17728 | -0.480 | -0.0511 | Yes |
| 176 | E2f2 | 17797 | -0.491 | -0.0414 | Yes |
| 177 | Ermap | 17854 | -0.506 | -0.0308 | Yes |
| 178 | Slc7a11 | 17882 | -0.513 | -0.0183 | Yes |
| 179 | Car1 | 17898 | -0.516 | -0.0051 | Yes |
| 180 | Abcg2 | 18046 | -0.552 | 0.0018 | Yes |
| 181 | Myl4 | 18257 | -0.663 | 0.0083 | Yes |

