| Dataset | CLP.Basophil_Pheno.cls #Group3_versus_Group4.Basophil_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | Basophil_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | -0.1803589 |
| Normalized Enrichment Score (NES) | -0.6236377 |
| Nominal p-value | 0.75409836 |
| FDR q-value | 0.94412595 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Meis2 | 636 | 0.563 | -0.0182 | No |
| 2 | Cdc25b | 1134 | 0.474 | -0.0314 | No |
| 3 | Cdkn2c | 1364 | 0.442 | -0.0309 | No |
| 4 | Cdkn3 | 1617 | 0.411 | -0.0325 | No |
| 5 | Pttg1 | 1890 | 0.381 | -0.0361 | No |
| 6 | Uck2 | 1934 | 0.377 | -0.0273 | No |
| 7 | Dmd | 1964 | 0.375 | -0.0178 | No |
| 8 | Dr1 | 2111 | 0.363 | -0.0150 | No |
| 9 | Cks1b | 2126 | 0.362 | -0.0051 | No |
| 10 | Efna5 | 2161 | 0.358 | 0.0037 | No |
| 11 | Odf2 | 2615 | 0.321 | -0.0116 | No |
| 12 | Amd1 | 2628 | 0.320 | -0.0028 | No |
| 13 | Cks2 | 2688 | 0.316 | 0.0034 | No |
| 14 | Tent4a | 2693 | 0.316 | 0.0125 | No |
| 15 | Upf1 | 3127 | 0.290 | -0.0027 | No |
| 16 | Cenpf | 3258 | 0.281 | -0.0015 | No |
| 17 | Atf5 | 3288 | 0.278 | 0.0052 | No |
| 18 | Srsf1 | 3299 | 0.277 | 0.0129 | No |
| 19 | Incenp | 3547 | 0.261 | 0.0071 | No |
| 20 | Map3k20 | 3558 | 0.261 | 0.0142 | No |
| 21 | Sap30 | 3634 | 0.255 | 0.0177 | No |
| 22 | Nek2 | 3927 | 0.240 | 0.0088 | No |
| 23 | Cenpa | 3970 | 0.237 | 0.0135 | No |
| 24 | Cdc20 | 3972 | 0.237 | 0.0205 | No |
| 25 | Ccnd1 | 4019 | 0.235 | 0.0249 | No |
| 26 | Ccnb2 | 4160 | 0.226 | 0.0239 | No |
| 27 | Nup98 | 4172 | 0.225 | 0.0300 | No |
| 28 | Cdkn1b | 4183 | 0.225 | 0.0361 | No |
| 29 | Dtymk | 4191 | 0.224 | 0.0424 | No |
| 30 | Ctcf | 4261 | 0.219 | 0.0451 | No |
| 31 | Sfpq | 4344 | 0.215 | 0.0470 | No |
| 32 | Rad21 | 4622 | 0.202 | 0.0378 | No |
| 33 | Prc1 | 4755 | 0.194 | 0.0363 | No |
| 34 | Hif1a | 4792 | 0.193 | 0.0400 | No |
| 35 | Ccnf | 4811 | 0.191 | 0.0447 | No |
| 36 | Kif20b | 4833 | 0.190 | 0.0492 | No |
| 37 | Stmn1 | 4847 | 0.189 | 0.0541 | No |
| 38 | Ube2s | 4937 | 0.185 | 0.0547 | No |
| 39 | Hmgb3 | 4945 | 0.185 | 0.0598 | No |
| 40 | Espl1 | 4972 | 0.184 | 0.0639 | No |
| 41 | Egf | 5067 | 0.180 | 0.0640 | No |
| 42 | Srsf2 | 5156 | 0.175 | 0.0644 | No |
| 43 | Bub3 | 5242 | 0.171 | 0.0648 | No |
| 44 | Tnpo2 | 5380 | 0.164 | 0.0621 | No |
| 45 | Ewsr1 | 5415 | 0.162 | 0.0651 | No |
| 46 | Kif11 | 5536 | 0.157 | 0.0631 | No |
| 47 | Plk1 | 5853 | 0.144 | 0.0501 | No |
| 48 | Aurkb | 5864 | 0.143 | 0.0538 | No |
| 49 | Kif4 | 5980 | 0.138 | 0.0515 | No |
| 50 | Dbf4 | 6067 | 0.134 | 0.0508 | No |
| 51 | Slc7a5 | 6099 | 0.132 | 0.0530 | No |
| 52 | Marcks | 6240 | 0.126 | 0.0491 | No |
| 53 | Hnrnpu | 6300 | 0.124 | 0.0495 | No |
| 54 | Ube2c | 6307 | 0.123 | 0.0528 | No |
| 55 | Jpt1 | 6531 | 0.113 | 0.0440 | No |
| 56 | Mki67 | 6543 | 0.113 | 0.0467 | No |
| 57 | Cenpe | 6588 | 0.111 | 0.0476 | No |
| 58 | Bub1 | 6597 | 0.111 | 0.0505 | No |
| 59 | Hmmr | 6690 | 0.107 | 0.0486 | No |
| 60 | Ccna2 | 6801 | 0.101 | 0.0455 | No |
| 61 | Cul3 | 6879 | 0.098 | 0.0442 | No |
| 62 | Prmt5 | 6973 | 0.094 | 0.0419 | No |
| 63 | Tle3 | 7299 | 0.085 | 0.0266 | No |
| 64 | Pafah1b1 | 7361 | 0.082 | 0.0257 | No |
| 65 | Cul5 | 7512 | 0.076 | 0.0197 | No |
| 66 | Kif23 | 7626 | 0.072 | 0.0156 | No |
| 67 | Kif15 | 7658 | 0.070 | 0.0160 | No |
| 68 | Syncrip | 7716 | 0.068 | 0.0149 | No |
| 69 | Top2a | 7792 | 0.065 | 0.0127 | No |
| 70 | Cdc27 | 7802 | 0.065 | 0.0141 | No |
| 71 | Chmp1a | 8305 | 0.045 | -0.0121 | No |
| 72 | Plk4 | 8408 | 0.040 | -0.0165 | No |
| 73 | Mapk14 | 8431 | 0.039 | -0.0165 | No |
| 74 | Nusap1 | 8468 | 0.038 | -0.0174 | No |
| 75 | Pds5b | 8484 | 0.037 | -0.0171 | No |
| 76 | Ilf3 | 8625 | 0.031 | -0.0239 | No |
| 77 | Tgfb1 | 8671 | 0.029 | -0.0255 | No |
| 78 | Knl1 | 8730 | 0.027 | -0.0279 | No |
| 79 | Nup50 | 8773 | 0.025 | -0.0294 | No |
| 80 | Troap | 8791 | 0.024 | -0.0296 | No |
| 81 | Tpx2 | 8801 | 0.024 | -0.0294 | No |
| 82 | Cdc7 | 8821 | 0.024 | -0.0298 | No |
| 83 | Katna1 | 8840 | 0.023 | -0.0301 | No |
| 84 | Numa1 | 8864 | 0.022 | -0.0307 | No |
| 85 | H2bc12 | 9022 | 0.016 | -0.0388 | No |
| 86 | Xpo1 | 9040 | 0.015 | -0.0393 | No |
| 87 | Sqle | 9059 | 0.015 | -0.0398 | No |
| 88 | Aurka | 9096 | 0.013 | -0.0414 | No |
| 89 | G3bp1 | 9129 | 0.012 | -0.0428 | No |
| 90 | Hira | 9156 | 0.011 | -0.0439 | No |
| 91 | Slc12a2 | 9168 | 0.011 | -0.0442 | No |
| 92 | Atrx | 9305 | 0.006 | -0.0515 | No |
| 93 | Bard1 | 9474 | 0.000 | -0.0607 | No |
| 94 | Tmpo | 9563 | -0.001 | -0.0655 | No |
| 95 | Kif2c | 9600 | -0.002 | -0.0674 | No |
| 96 | Racgap1 | 9651 | -0.004 | -0.0700 | No |
| 97 | Slc7a1 | 9691 | -0.006 | -0.0720 | No |
| 98 | Ndc80 | 9742 | -0.008 | -0.0745 | No |
| 99 | E2f4 | 9926 | -0.014 | -0.0841 | No |
| 100 | Smc2 | 9952 | -0.015 | -0.0851 | No |
| 101 | Smad3 | 10138 | -0.021 | -0.0946 | No |
| 102 | Notch2 | 10230 | -0.024 | -0.0989 | No |
| 103 | H2ax | 10247 | -0.025 | -0.0990 | No |
| 104 | Lmnb1 | 10264 | -0.026 | -0.0991 | No |
| 105 | Fancc | 10591 | -0.039 | -0.1158 | No |
| 106 | Meis1 | 10674 | -0.042 | -0.1191 | No |
| 107 | Kpnb1 | 10691 | -0.042 | -0.1187 | No |
| 108 | Ythdc1 | 10760 | -0.045 | -0.1211 | No |
| 109 | Tacc3 | 10861 | -0.049 | -0.1252 | No |
| 110 | Lbr | 10879 | -0.049 | -0.1246 | No |
| 111 | Foxn3 | 10974 | -0.052 | -0.1282 | No |
| 112 | Birc5 | 11099 | -0.056 | -0.1334 | No |
| 113 | Mad2l1 | 11123 | -0.057 | -0.1330 | No |
| 114 | Smc4 | 11137 | -0.057 | -0.1320 | No |
| 115 | Hspa8 | 11221 | -0.061 | -0.1347 | No |
| 116 | Bcl3 | 11240 | -0.062 | -0.1339 | No |
| 117 | Kmt5a | 11301 | -0.064 | -0.1353 | No |
| 118 | Slc38a1 | 11490 | -0.071 | -0.1435 | No |
| 119 | Mcm2 | 11502 | -0.071 | -0.1420 | No |
| 120 | Top1 | 11504 | -0.071 | -0.1400 | No |
| 121 | Pbk | 11689 | -0.078 | -0.1477 | No |
| 122 | Fbxo5 | 11765 | -0.082 | -0.1494 | No |
| 123 | Pole | 11782 | -0.082 | -0.1479 | No |
| 124 | Nsd2 | 11806 | -0.083 | -0.1467 | No |
| 125 | Kif22 | 11851 | -0.084 | -0.1466 | No |
| 126 | Cul1 | 11896 | -0.086 | -0.1464 | No |
| 127 | Cdk1 | 11948 | -0.089 | -0.1466 | No |
| 128 | Pura | 11988 | -0.090 | -0.1461 | No |
| 129 | Kif5b | 12011 | -0.091 | -0.1445 | No |
| 130 | Hus1 | 12131 | -0.096 | -0.1482 | No |
| 131 | Gins2 | 12149 | -0.097 | -0.1463 | No |
| 132 | Ttk | 12179 | -0.098 | -0.1450 | No |
| 133 | Cdk4 | 12201 | -0.098 | -0.1432 | No |
| 134 | Hnrnpd | 12350 | -0.105 | -0.1483 | No |
| 135 | Ddx39a | 12469 | -0.110 | -0.1515 | No |
| 136 | Arid4a | 12493 | -0.111 | -0.1495 | No |
| 137 | Smarcc1 | 12526 | -0.112 | -0.1479 | No |
| 138 | Rps6ka5 | 12619 | -0.116 | -0.1495 | No |
| 139 | H2az2 | 12652 | -0.117 | -0.1478 | No |
| 140 | Rad23b | 12714 | -0.120 | -0.1476 | No |
| 141 | Mnat1 | 12741 | -0.121 | -0.1454 | No |
| 142 | Gspt1 | 12832 | -0.125 | -0.1467 | No |
| 143 | Stag1 | 13052 | -0.134 | -0.1547 | No |
| 144 | Rbl1 | 13150 | -0.139 | -0.1559 | No |
| 145 | Srsf10 | 13181 | -0.140 | -0.1534 | No |
| 146 | Rasal2 | 13300 | -0.145 | -0.1555 | No |
| 147 | Ss18 | 13345 | -0.147 | -0.1536 | No |
| 148 | Prpf4b | 13409 | -0.150 | -0.1526 | No |
| 149 | Cbx1 | 13688 | -0.164 | -0.1630 | No |
| 150 | Mcm6 | 13725 | -0.165 | -0.1601 | No |
| 151 | Polq | 13849 | -0.171 | -0.1618 | No |
| 152 | Smc1a | 14112 | -0.184 | -0.1707 | No |
| 153 | Tra2b | 14191 | -0.188 | -0.1694 | No |
| 154 | E2f3 | 14392 | -0.199 | -0.1745 | Yes |
| 155 | Mtf2 | 14401 | -0.199 | -0.1690 | Yes |
| 156 | Tfdp1 | 14474 | -0.202 | -0.1669 | Yes |
| 157 | E2f1 | 14591 | -0.207 | -0.1672 | Yes |
| 158 | Myc | 14626 | -0.209 | -0.1628 | Yes |
| 159 | Chaf1a | 14701 | -0.213 | -0.1606 | Yes |
| 160 | Rad54l | 14755 | -0.216 | -0.1571 | Yes |
| 161 | Chek1 | 14950 | -0.227 | -0.1610 | Yes |
| 162 | Brca2 | 15009 | -0.231 | -0.1573 | Yes |
| 163 | Ezh2 | 15198 | -0.239 | -0.1605 | Yes |
| 164 | Cul4a | 15236 | -0.242 | -0.1554 | Yes |
| 165 | Mybl2 | 15256 | -0.243 | -0.1492 | Yes |
| 166 | Mcm5 | 15265 | -0.244 | -0.1424 | Yes |
| 167 | Odc1 | 15391 | -0.252 | -0.1417 | Yes |
| 168 | Ncl | 15469 | -0.257 | -0.1383 | Yes |
| 169 | Nasp | 15561 | -0.263 | -0.1355 | Yes |
| 170 | Wrn | 15623 | -0.268 | -0.1309 | Yes |
| 171 | Ccnt1 | 15818 | -0.281 | -0.1332 | Yes |
| 172 | Mcm3 | 15943 | -0.290 | -0.1314 | Yes |
| 173 | Cdc45 | 16082 | -0.299 | -0.1301 | Yes |
| 174 | Abl1 | 16121 | -0.303 | -0.1232 | Yes |
| 175 | Rpa2 | 16320 | -0.315 | -0.1247 | Yes |
| 176 | Pola2 | 16379 | -0.320 | -0.1184 | Yes |
| 177 | H2az1 | 16409 | -0.323 | -0.1104 | Yes |
| 178 | Exo1 | 16593 | -0.339 | -0.1104 | Yes |
| 179 | Lig3 | 16644 | -0.342 | -0.1030 | Yes |
| 180 | Orc5 | 16698 | -0.346 | -0.0956 | Yes |
| 181 | Dkc1 | 16755 | -0.351 | -0.0883 | Yes |
| 182 | Casp8ap2 | 16818 | -0.356 | -0.0811 | Yes |
| 183 | Pml | 16828 | -0.358 | -0.0710 | Yes |
| 184 | Traip | 17020 | -0.376 | -0.0703 | Yes |
| 185 | Prim2 | 17176 | -0.395 | -0.0671 | Yes |
| 186 | Cdc6 | 17254 | -0.407 | -0.0593 | Yes |
| 187 | Suv39h1 | 17527 | -0.445 | -0.0610 | Yes |
| 188 | Hmga1b | 17565 | -0.451 | -0.0496 | Yes |
| 189 | E2f2 | 17797 | -0.491 | -0.0477 | Yes |
| 190 | Stil | 17871 | -0.510 | -0.0366 | Yes |
| 191 | Nolc1 | 17917 | -0.519 | -0.0237 | Yes |
| 192 | Snrpd1 | 17956 | -0.528 | -0.0101 | Yes |
| 193 | Cdc25a | 18114 | -0.579 | -0.0015 | Yes |
| 194 | Orc6 | 18148 | -0.593 | 0.0143 | Yes |

