| Dataset | CLP.Basophil_Pheno.cls #Group2_versus_Group4.Basophil_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | Basophil_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | 0.23123524 |
| Normalized Enrichment Score (NES) | 1.0116528 |
| Nominal p-value | 0.436 |
| FDR q-value | 0.8884087 |
| FWER p-Value | 0.998 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Gla | 100 | 0.800 | 0.0116 | Yes |
| 2 | Hspa9 | 114 | 0.789 | 0.0277 | Yes |
| 3 | Idh1 | 288 | 0.662 | 0.0323 | Yes |
| 4 | Hmgcs1 | 343 | 0.638 | 0.0429 | Yes |
| 5 | Mcm4 | 344 | 0.638 | 0.0565 | Yes |
| 6 | Hspa4 | 397 | 0.621 | 0.0669 | Yes |
| 7 | Vldlr | 404 | 0.616 | 0.0797 | Yes |
| 8 | Tm7sf2 | 569 | 0.565 | 0.0827 | Yes |
| 9 | Rpn1 | 668 | 0.544 | 0.0889 | Yes |
| 10 | Pik3r3 | 687 | 0.541 | 0.0995 | Yes |
| 11 | Abcf2 | 778 | 0.524 | 0.1057 | Yes |
| 12 | Tfrc | 864 | 0.508 | 0.1119 | Yes |
| 13 | Me1 | 897 | 0.503 | 0.1208 | Yes |
| 14 | Bhlhe40 | 920 | 0.497 | 0.1302 | Yes |
| 15 | Fgl2 | 974 | 0.490 | 0.1377 | Yes |
| 16 | Gsr | 1063 | 0.478 | 0.1431 | Yes |
| 17 | Canx | 1094 | 0.472 | 0.1515 | Yes |
| 18 | Skap2 | 1188 | 0.460 | 0.1562 | Yes |
| 19 | Niban1 | 1209 | 0.458 | 0.1649 | Yes |
| 20 | Stard4 | 1256 | 0.451 | 0.1719 | Yes |
| 21 | Gpi1 | 1299 | 0.446 | 0.1792 | Yes |
| 22 | Mcm2 | 1438 | 0.429 | 0.1807 | Yes |
| 23 | Lgmn | 1609 | 0.412 | 0.1802 | Yes |
| 24 | Immt | 1773 | 0.395 | 0.1796 | Yes |
| 25 | G6pdx | 1870 | 0.385 | 0.1826 | Yes |
| 26 | Hspd1 | 1999 | 0.373 | 0.1835 | Yes |
| 27 | Add3 | 2001 | 0.372 | 0.1914 | Yes |
| 28 | M6pr | 2044 | 0.369 | 0.1969 | Yes |
| 29 | Actr2 | 2078 | 0.366 | 0.2029 | Yes |
| 30 | Ak4 | 2167 | 0.361 | 0.2058 | Yes |
| 31 | Edem1 | 2229 | 0.355 | 0.2100 | Yes |
| 32 | Sqle | 2257 | 0.351 | 0.2160 | Yes |
| 33 | Pnp | 2552 | 0.325 | 0.2068 | Yes |
| 34 | Actr3 | 2631 | 0.321 | 0.2093 | Yes |
| 35 | Serpinh1 | 3152 | 0.283 | 0.1868 | Yes |
| 36 | Serp1 | 3157 | 0.283 | 0.1926 | Yes |
| 37 | Nup205 | 3286 | 0.275 | 0.1914 | Yes |
| 38 | Rit1 | 3535 | 0.261 | 0.1834 | Yes |
| 39 | Rrp9 | 3580 | 0.257 | 0.1865 | Yes |
| 40 | Rrm2 | 3700 | 0.249 | 0.1852 | Yes |
| 41 | Got1 | 3770 | 0.243 | 0.1866 | Yes |
| 42 | Calr | 3777 | 0.242 | 0.1915 | Yes |
| 43 | Nufip1 | 3799 | 0.241 | 0.1954 | Yes |
| 44 | Etf1 | 3875 | 0.235 | 0.1963 | Yes |
| 45 | Psmc4 | 3911 | 0.232 | 0.1993 | Yes |
| 46 | Gmps | 4010 | 0.227 | 0.1988 | Yes |
| 47 | Slc7a11 | 4028 | 0.226 | 0.2027 | Yes |
| 48 | Hsp90b1 | 4030 | 0.225 | 0.2074 | Yes |
| 49 | Gsk3b | 4037 | 0.225 | 0.2119 | Yes |
| 50 | Mthfd2l | 4091 | 0.223 | 0.2137 | Yes |
| 51 | Stip1 | 4096 | 0.222 | 0.2182 | Yes |
| 52 | Cct6a | 4138 | 0.221 | 0.2207 | Yes |
| 53 | Hmbs | 4164 | 0.219 | 0.2240 | Yes |
| 54 | Acsl3 | 4180 | 0.218 | 0.2278 | Yes |
| 55 | Ifi30 | 4242 | 0.215 | 0.2291 | Yes |
| 56 | Cyb5b | 4350 | 0.210 | 0.2277 | Yes |
| 57 | Pno1 | 4456 | 0.203 | 0.2262 | Yes |
| 58 | Rab1a | 4472 | 0.202 | 0.2297 | Yes |
| 59 | Nfil3 | 4523 | 0.200 | 0.2312 | Yes |
| 60 | Bub1 | 4721 | 0.191 | 0.2245 | No |
| 61 | Atp2a2 | 4821 | 0.184 | 0.2230 | No |
| 62 | Uso1 | 4908 | 0.179 | 0.2221 | No |
| 63 | Atp6v1d | 4949 | 0.176 | 0.2236 | No |
| 64 | Pitpnb | 5027 | 0.171 | 0.2230 | No |
| 65 | Slc6a6 | 5081 | 0.169 | 0.2237 | No |
| 66 | Itgb2 | 5121 | 0.167 | 0.2251 | No |
| 67 | Aurka | 5133 | 0.166 | 0.2281 | No |
| 68 | Gga2 | 5261 | 0.160 | 0.2245 | No |
| 69 | Txnrd1 | 5327 | 0.157 | 0.2243 | No |
| 70 | Psmc6 | 5452 | 0.152 | 0.2207 | No |
| 71 | Prdx1 | 5658 | 0.142 | 0.2125 | No |
| 72 | Rdh11 | 5726 | 0.138 | 0.2118 | No |
| 73 | Fdxr | 5826 | 0.132 | 0.2091 | No |
| 74 | Ddit4 | 5907 | 0.129 | 0.2075 | No |
| 75 | Sla | 6021 | 0.123 | 0.2039 | No |
| 76 | Ldlr | 6071 | 0.120 | 0.2038 | No |
| 77 | Hmgcr | 6301 | 0.108 | 0.1935 | No |
| 78 | Ufm1 | 6401 | 0.103 | 0.1903 | No |
| 79 | Nfyc | 6442 | 0.101 | 0.1902 | No |
| 80 | Ctsc | 6735 | 0.090 | 0.1761 | No |
| 81 | Ube2d3 | 6776 | 0.089 | 0.1758 | No |
| 82 | Qdpr | 6778 | 0.089 | 0.1777 | No |
| 83 | Psme3 | 6784 | 0.089 | 0.1793 | No |
| 84 | Hspa5 | 6913 | 0.082 | 0.1740 | No |
| 85 | Ssr1 | 6924 | 0.082 | 0.1752 | No |
| 86 | Cacybp | 6949 | 0.081 | 0.1756 | No |
| 87 | Acly | 7098 | 0.074 | 0.1691 | No |
| 88 | Plk1 | 7267 | 0.067 | 0.1613 | No |
| 89 | Dhfr | 7275 | 0.067 | 0.1623 | No |
| 90 | P4ha1 | 7346 | 0.063 | 0.1598 | No |
| 91 | Xbp1 | 7429 | 0.058 | 0.1566 | No |
| 92 | Gbe1 | 7522 | 0.054 | 0.1527 | No |
| 93 | Tcea1 | 7548 | 0.053 | 0.1524 | No |
| 94 | Cops5 | 7618 | 0.050 | 0.1497 | No |
| 95 | Hk2 | 7631 | 0.049 | 0.1501 | No |
| 96 | Idi1 | 7811 | 0.041 | 0.1411 | No |
| 97 | Cdc25a | 7824 | 0.040 | 0.1413 | No |
| 98 | Psmc2 | 8053 | 0.030 | 0.1294 | No |
| 99 | Psmd14 | 8210 | 0.023 | 0.1214 | No |
| 100 | Dhcr24 | 8243 | 0.022 | 0.1201 | No |
| 101 | Ppa1 | 8291 | 0.020 | 0.1179 | No |
| 102 | Pdk1 | 8318 | 0.019 | 0.1169 | No |
| 103 | Map2k3 | 8398 | 0.016 | 0.1129 | No |
| 104 | Elovl6 | 8540 | 0.010 | 0.1054 | No |
| 105 | Ddx39a | 8591 | 0.008 | 0.1028 | No |
| 106 | Ccnf | 8921 | -0.003 | 0.0848 | No |
| 107 | Sytl2 | 9006 | -0.008 | 0.0804 | No |
| 108 | Tpi1 | 9085 | -0.011 | 0.0763 | No |
| 109 | Slc37a4 | 9445 | -0.026 | 0.0572 | No |
| 110 | Psma3 | 9578 | -0.031 | 0.0506 | No |
| 111 | Aldoa | 9594 | -0.032 | 0.0505 | No |
| 112 | Rpa1 | 10059 | -0.053 | 0.0261 | No |
| 113 | Slc1a5 | 10313 | -0.065 | 0.0136 | No |
| 114 | Eno1b | 10439 | -0.069 | 0.0082 | No |
| 115 | Gclc | 10447 | -0.069 | 0.0093 | No |
| 116 | Glrx | 10548 | -0.075 | 0.0054 | No |
| 117 | Asns | 10650 | -0.079 | 0.0016 | No |
| 118 | Slc1a4 | 10680 | -0.081 | 0.0017 | No |
| 119 | Sqstm1 | 10772 | -0.085 | -0.0015 | No |
| 120 | Egln3 | 10845 | -0.088 | -0.0036 | No |
| 121 | Wars1 | 10873 | -0.089 | -0.0032 | No |
| 122 | Sord | 11015 | -0.095 | -0.0089 | No |
| 123 | Gtf2h1 | 11023 | -0.096 | -0.0072 | No |
| 124 | Ppia | 11105 | -0.099 | -0.0095 | No |
| 125 | Adipor2 | 11359 | -0.109 | -0.0211 | No |
| 126 | Slc7a5 | 11408 | -0.111 | -0.0214 | No |
| 127 | Fads2 | 11417 | -0.111 | -0.0194 | No |
| 128 | Mthfd2 | 11455 | -0.113 | -0.0191 | No |
| 129 | Ppp1r15a | 11694 | -0.123 | -0.0295 | No |
| 130 | Elovl5 | 11730 | -0.124 | -0.0288 | No |
| 131 | Cyp51 | 11781 | -0.127 | -0.0288 | No |
| 132 | Cdkn1a | 11830 | -0.130 | -0.0287 | No |
| 133 | Ung | 11837 | -0.130 | -0.0262 | No |
| 134 | Ccng1 | 11922 | -0.133 | -0.0280 | No |
| 135 | Psph | 12468 | -0.159 | -0.0545 | No |
| 136 | Dhcr7 | 12501 | -0.161 | -0.0529 | No |
| 137 | Bcat1 | 12594 | -0.164 | -0.0544 | No |
| 138 | Psat1 | 12605 | -0.165 | -0.0514 | No |
| 139 | Cd9 | 12723 | -0.171 | -0.0542 | No |
| 140 | Lta4h | 12746 | -0.173 | -0.0517 | No |
| 141 | Psmb5 | 12756 | -0.173 | -0.0485 | No |
| 142 | Slc2a1 | 12813 | -0.176 | -0.0479 | No |
| 143 | Psmd12 | 12874 | -0.180 | -0.0473 | No |
| 144 | Srd5a1 | 13132 | -0.191 | -0.0573 | No |
| 145 | Nmt1 | 13226 | -0.196 | -0.0583 | No |
| 146 | Fads1 | 13337 | -0.202 | -0.0600 | No |
| 147 | Sec11a | 13344 | -0.202 | -0.0560 | No |
| 148 | Tomm40 | 13365 | -0.204 | -0.0528 | No |
| 149 | Plod2 | 13546 | -0.211 | -0.0581 | No |
| 150 | Shmt2 | 13703 | -0.217 | -0.0621 | No |
| 151 | Ero1a | 14004 | -0.232 | -0.0736 | No |
| 152 | Tes | 14045 | -0.234 | -0.0708 | No |
| 153 | Pfkl | 14281 | -0.246 | -0.0785 | No |
| 154 | Polr3g | 14324 | -0.249 | -0.0755 | No |
| 155 | Ykt6 | 14345 | -0.250 | -0.0712 | No |
| 156 | Insig1 | 14388 | -0.253 | -0.0681 | No |
| 157 | Sc5d | 14437 | -0.255 | -0.0654 | No |
| 158 | Tbk1 | 14478 | -0.257 | -0.0621 | No |
| 159 | Pgk1 | 14492 | -0.258 | -0.0573 | No |
| 160 | Uchl5 | 14597 | -0.264 | -0.0574 | No |
| 161 | Cxcr4 | 14718 | -0.271 | -0.0582 | No |
| 162 | Tubg1 | 14724 | -0.271 | -0.0527 | No |
| 163 | Cth | 14765 | -0.272 | -0.0491 | No |
| 164 | Btg2 | 14930 | -0.282 | -0.0521 | No |
| 165 | Nampt | 14954 | -0.284 | -0.0473 | No |
| 166 | Acaca | 14962 | -0.284 | -0.0416 | No |
| 167 | Pdap1 | 15043 | -0.289 | -0.0398 | No |
| 168 | Ldha | 15245 | -0.300 | -0.0445 | No |
| 169 | Phgdh | 15296 | -0.303 | -0.0407 | No |
| 170 | Dapp1 | 15485 | -0.315 | -0.0443 | No |
| 171 | Arpc5l | 15629 | -0.325 | -0.0453 | No |
| 172 | Psmd13 | 15893 | -0.343 | -0.0524 | No |
| 173 | Psmg1 | 15927 | -0.345 | -0.0469 | No |
| 174 | Pgm1 | 16029 | -0.352 | -0.0449 | No |
| 175 | Tuba4a | 16147 | -0.362 | -0.0436 | No |
| 176 | Hspe1 | 16174 | -0.364 | -0.0373 | No |
| 177 | Eif2s2 | 16277 | -0.371 | -0.0350 | No |
| 178 | Ifrd1 | 16406 | -0.383 | -0.0338 | No |
| 179 | Coro1a | 16439 | -0.386 | -0.0274 | No |
| 180 | Tmem97 | 16491 | -0.391 | -0.0218 | No |
| 181 | Fkbp2 | 16683 | -0.408 | -0.0236 | No |
| 182 | Cfp | 17409 | -0.490 | -0.0530 | No |
| 183 | Psma4 | 17448 | -0.496 | -0.0445 | No |
| 184 | Sdf2l1 | 17511 | -0.508 | -0.0371 | No |
| 185 | Slc2a3 | 17666 | -0.535 | -0.0341 | No |
| 186 | Nfkbib | 17692 | -0.543 | -0.0239 | No |
| 187 | Ddit3 | 17713 | -0.547 | -0.0134 | No |
| 188 | Mllt11 | 17793 | -0.561 | -0.0057 | No |
| 189 | Trib3 | 17838 | -0.570 | 0.0040 | No |
| 190 | Eef1e1 | 18035 | -0.629 | 0.0066 | No |
| 191 | Ebp | 18072 | -0.646 | 0.0184 | No |

