| Dataset | CLP.Basophil_Pheno.cls #Group2_versus_Group4.Basophil_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | Basophil_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.32850635 |
| Normalized Enrichment Score (NES) | 1.1556597 |
| Nominal p-value | 0.36738703 |
| FDR q-value | 0.83975095 |
| FWER p-Value | 0.96 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Srsf1 | 190 | 0.714 | 0.0078 | Yes |
| 2 | Donson | 273 | 0.667 | 0.0203 | Yes |
| 3 | Mcm4 | 344 | 0.638 | 0.0328 | Yes |
| 4 | Cdkn1b | 528 | 0.575 | 0.0374 | Yes |
| 5 | Tfrc | 864 | 0.508 | 0.0320 | Yes |
| 6 | Msh2 | 886 | 0.504 | 0.0437 | Yes |
| 7 | Melk | 1020 | 0.484 | 0.0487 | Yes |
| 8 | Ssrp1 | 1082 | 0.475 | 0.0575 | Yes |
| 9 | Rpa3 | 1174 | 0.460 | 0.0643 | Yes |
| 10 | Dck | 1210 | 0.458 | 0.0740 | Yes |
| 11 | Lmnb1 | 1281 | 0.448 | 0.0816 | Yes |
| 12 | Ncapd2 | 1421 | 0.431 | 0.0850 | Yes |
| 13 | Mcm2 | 1438 | 0.429 | 0.0951 | Yes |
| 14 | Ipo7 | 1447 | 0.428 | 0.1056 | Yes |
| 15 | Rbbp7 | 1483 | 0.426 | 0.1145 | Yes |
| 16 | Prps1 | 1562 | 0.417 | 0.1209 | Yes |
| 17 | Nasp | 1566 | 0.417 | 0.1314 | Yes |
| 18 | Trip13 | 1671 | 0.406 | 0.1360 | Yes |
| 19 | Mcm3 | 1774 | 0.395 | 0.1405 | Yes |
| 20 | Aurkb | 1840 | 0.387 | 0.1468 | Yes |
| 21 | Dnmt1 | 1871 | 0.384 | 0.1550 | Yes |
| 22 | Hus1 | 1888 | 0.383 | 0.1639 | Yes |
| 23 | Smc1a | 1997 | 0.373 | 0.1675 | Yes |
| 24 | Hells | 2183 | 0.360 | 0.1665 | Yes |
| 25 | Pttg1 | 2273 | 0.350 | 0.1706 | Yes |
| 26 | Xpo1 | 2288 | 0.349 | 0.1787 | Yes |
| 27 | Hnrnpd | 2326 | 0.346 | 0.1855 | Yes |
| 28 | Ube2t | 2365 | 0.342 | 0.1921 | Yes |
| 29 | Prkdc | 2386 | 0.340 | 0.1997 | Yes |
| 30 | Timeless | 2430 | 0.335 | 0.2059 | Yes |
| 31 | Psmc3ip | 2451 | 0.333 | 0.2133 | Yes |
| 32 | Lsm8 | 2455 | 0.333 | 0.2216 | Yes |
| 33 | Gins4 | 2526 | 0.327 | 0.2262 | Yes |
| 34 | Lbr | 2761 | 0.312 | 0.2213 | Yes |
| 35 | Paics | 2858 | 0.304 | 0.2238 | Yes |
| 36 | Mcm6 | 3006 | 0.293 | 0.2232 | Yes |
| 37 | Asf1a | 3097 | 0.288 | 0.2256 | Yes |
| 38 | Top2a | 3252 | 0.278 | 0.2242 | Yes |
| 39 | Mcm5 | 3276 | 0.276 | 0.2300 | Yes |
| 40 | Nup205 | 3286 | 0.275 | 0.2365 | Yes |
| 41 | Pole | 3360 | 0.271 | 0.2394 | Yes |
| 42 | Syncrip | 3407 | 0.268 | 0.2438 | Yes |
| 43 | Mybl2 | 3533 | 0.261 | 0.2436 | Yes |
| 44 | Nap1l1 | 3627 | 0.254 | 0.2450 | Yes |
| 45 | Rfc1 | 3640 | 0.253 | 0.2507 | Yes |
| 46 | Spc25 | 3650 | 0.252 | 0.2567 | Yes |
| 47 | Bard1 | 3657 | 0.252 | 0.2628 | Yes |
| 48 | Stmn1 | 3677 | 0.250 | 0.2681 | Yes |
| 49 | Rrm2 | 3700 | 0.249 | 0.2733 | Yes |
| 50 | Rad21 | 3715 | 0.247 | 0.2788 | Yes |
| 51 | Nup107 | 3811 | 0.240 | 0.2797 | Yes |
| 52 | Ctcf | 3828 | 0.239 | 0.2849 | Yes |
| 53 | Chek2 | 3871 | 0.235 | 0.2886 | Yes |
| 54 | Brca1 | 3878 | 0.235 | 0.2943 | Yes |
| 55 | Pnn | 3893 | 0.233 | 0.2995 | Yes |
| 56 | Prim2 | 3940 | 0.231 | 0.3028 | Yes |
| 57 | Smc3 | 3947 | 0.230 | 0.3084 | Yes |
| 58 | Cdkn2c | 3969 | 0.228 | 0.3131 | Yes |
| 59 | Lig1 | 4083 | 0.223 | 0.3126 | Yes |
| 60 | Tipin | 4224 | 0.216 | 0.3104 | Yes |
| 61 | Ube2s | 4272 | 0.214 | 0.3133 | Yes |
| 62 | Atad2 | 4274 | 0.214 | 0.3187 | Yes |
| 63 | Cdca8 | 4494 | 0.202 | 0.3118 | Yes |
| 64 | Spc24 | 4531 | 0.199 | 0.3149 | Yes |
| 65 | Dlgap5 | 4659 | 0.194 | 0.3129 | Yes |
| 66 | Kif4 | 4713 | 0.192 | 0.3148 | Yes |
| 67 | Cdkn3 | 4787 | 0.187 | 0.3156 | Yes |
| 68 | Bub1b | 4862 | 0.181 | 0.3162 | Yes |
| 69 | Chek1 | 4919 | 0.178 | 0.3176 | Yes |
| 70 | Hmgb2 | 4945 | 0.176 | 0.3208 | Yes |
| 71 | Anp32e | 4964 | 0.175 | 0.3243 | Yes |
| 72 | Psip1 | 4999 | 0.173 | 0.3268 | Yes |
| 73 | Tmpo | 5048 | 0.170 | 0.3285 | Yes |
| 74 | Aurka | 5133 | 0.166 | 0.3281 | No |
| 75 | Ppp1r8 | 5254 | 0.161 | 0.3256 | No |
| 76 | Slbp | 5304 | 0.158 | 0.3270 | No |
| 77 | Cbx5 | 5671 | 0.141 | 0.3105 | No |
| 78 | Smc6 | 5745 | 0.137 | 0.3099 | No |
| 79 | Ilf3 | 5827 | 0.132 | 0.3089 | No |
| 80 | Brca2 | 6077 | 0.119 | 0.2982 | No |
| 81 | Wee1 | 6103 | 0.118 | 0.2999 | No |
| 82 | Mad2l1 | 6167 | 0.115 | 0.2994 | No |
| 83 | Cks2 | 6238 | 0.112 | 0.2984 | No |
| 84 | Ccp110 | 6333 | 0.106 | 0.2959 | No |
| 85 | Mcm7 | 6345 | 0.106 | 0.2980 | No |
| 86 | Cdkn2a | 6365 | 0.105 | 0.2996 | No |
| 87 | Cse1l | 6460 | 0.100 | 0.2971 | No |
| 88 | Eif2s1 | 6870 | 0.084 | 0.2767 | No |
| 89 | Wdr90 | 6976 | 0.079 | 0.2730 | No |
| 90 | Pds5b | 6998 | 0.079 | 0.2739 | No |
| 91 | Exosc8 | 7169 | 0.071 | 0.2663 | No |
| 92 | Pold3 | 7259 | 0.067 | 0.2632 | No |
| 93 | Plk1 | 7267 | 0.067 | 0.2645 | No |
| 94 | Rad51ap1 | 7311 | 0.064 | 0.2638 | No |
| 95 | Brms1l | 7336 | 0.063 | 0.2641 | No |
| 96 | Cdk1 | 7339 | 0.063 | 0.2656 | No |
| 97 | Pcna | 7405 | 0.060 | 0.2635 | No |
| 98 | Stag1 | 7414 | 0.059 | 0.2646 | No |
| 99 | Ak2 | 7438 | 0.058 | 0.2648 | No |
| 100 | Espl1 | 7484 | 0.056 | 0.2638 | No |
| 101 | Cenpe | 7587 | 0.051 | 0.2594 | No |
| 102 | Shmt1 | 7707 | 0.046 | 0.2541 | No |
| 103 | Gspt1 | 7805 | 0.041 | 0.2498 | No |
| 104 | Cdc25a | 7824 | 0.040 | 0.2498 | No |
| 105 | Xrcc6 | 7921 | 0.036 | 0.2455 | No |
| 106 | Luc7l3 | 7926 | 0.036 | 0.2462 | No |
| 107 | E2f8 | 7933 | 0.036 | 0.2467 | No |
| 108 | Hmgb3 | 7984 | 0.033 | 0.2449 | No |
| 109 | Kif22 | 7991 | 0.033 | 0.2454 | No |
| 110 | Tubb5 | 8026 | 0.032 | 0.2443 | No |
| 111 | Mre11a | 8036 | 0.031 | 0.2446 | No |
| 112 | Dctpp1 | 8048 | 0.031 | 0.2448 | No |
| 113 | Racgap1 | 8158 | 0.025 | 0.2395 | No |
| 114 | Hmmr | 8169 | 0.025 | 0.2395 | No |
| 115 | Rad51c | 8232 | 0.023 | 0.2367 | No |
| 116 | Cdk4 | 8258 | 0.022 | 0.2359 | No |
| 117 | Rnaseh2a | 8325 | 0.019 | 0.2328 | No |
| 118 | Pa2g4 | 8496 | 0.012 | 0.2237 | No |
| 119 | Mki67 | 8581 | 0.008 | 0.2193 | No |
| 120 | Ddx39a | 8591 | 0.008 | 0.2190 | No |
| 121 | Rad1 | 8630 | 0.006 | 0.2171 | No |
| 122 | Cdc25b | 8683 | 0.004 | 0.2144 | No |
| 123 | Gins1 | 8885 | -0.002 | 0.2034 | No |
| 124 | Rad50 | 9182 | -0.014 | 0.1875 | No |
| 125 | Plk4 | 9193 | -0.015 | 0.1873 | No |
| 126 | Asf1b | 9238 | -0.017 | 0.1853 | No |
| 127 | Diaph3 | 9263 | -0.018 | 0.1844 | No |
| 128 | Kif18b | 9305 | -0.020 | 0.1827 | No |
| 129 | Dut | 9409 | -0.024 | 0.1777 | No |
| 130 | Pms2 | 9435 | -0.026 | 0.1770 | No |
| 131 | Cnot9 | 9469 | -0.027 | 0.1758 | No |
| 132 | Ubr7 | 9495 | -0.028 | 0.1752 | No |
| 133 | Depdc1a | 9555 | -0.030 | 0.1727 | No |
| 134 | Nop56 | 9669 | -0.036 | 0.1674 | No |
| 135 | Smc4 | 9720 | -0.038 | 0.1656 | No |
| 136 | Rfc2 | 9785 | -0.040 | 0.1632 | No |
| 137 | Ccne1 | 9839 | -0.043 | 0.1613 | No |
| 138 | Tbrg4 | 9853 | -0.043 | 0.1617 | No |
| 139 | Nup153 | 9881 | -0.045 | 0.1614 | No |
| 140 | Cit | 9889 | -0.045 | 0.1622 | No |
| 141 | Rfc3 | 9894 | -0.045 | 0.1631 | No |
| 142 | Nudt21 | 10018 | -0.051 | 0.1576 | No |
| 143 | Rpa1 | 10059 | -0.053 | 0.1568 | No |
| 144 | Nme1 | 10152 | -0.057 | 0.1532 | No |
| 145 | Cks1b | 10265 | -0.062 | 0.1486 | No |
| 146 | Rpa2 | 10322 | -0.065 | 0.1472 | No |
| 147 | Cenpm | 10477 | -0.071 | 0.1406 | No |
| 148 | Kif2c | 10523 | -0.073 | 0.1400 | No |
| 149 | Tra2b | 10707 | -0.082 | 0.1320 | No |
| 150 | Ezh2 | 10714 | -0.083 | 0.1338 | No |
| 151 | Pole4 | 10780 | -0.085 | 0.1324 | No |
| 152 | Pan2 | 10941 | -0.092 | 0.1260 | No |
| 153 | Birc5 | 11050 | -0.097 | 0.1225 | No |
| 154 | Ranbp1 | 11073 | -0.098 | 0.1238 | No |
| 155 | Mxd3 | 11319 | -0.107 | 0.1131 | No |
| 156 | Mthfd2 | 11455 | -0.113 | 0.1085 | No |
| 157 | Usp1 | 11489 | -0.114 | 0.1096 | No |
| 158 | Mms22l | 11649 | -0.121 | 0.1040 | No |
| 159 | Zw10 | 11753 | -0.125 | 0.1015 | No |
| 160 | Spag5 | 11820 | -0.129 | 0.1012 | No |
| 161 | Cdkn1a | 11830 | -0.130 | 0.1040 | No |
| 162 | Ung | 11837 | -0.130 | 0.1070 | No |
| 163 | Pold1 | 11838 | -0.130 | 0.1103 | No |
| 164 | Ran | 11923 | -0.133 | 0.1091 | No |
| 165 | Srsf2 | 12059 | -0.140 | 0.1053 | No |
| 166 | Tacc3 | 12079 | -0.141 | 0.1078 | No |
| 167 | Nolc1 | 12163 | -0.145 | 0.1070 | No |
| 168 | Pola2 | 12330 | -0.152 | 0.1017 | No |
| 169 | Tk1 | 12403 | -0.156 | 0.1018 | No |
| 170 | Tcf19 | 12502 | -0.161 | 0.1005 | No |
| 171 | Dek | 12544 | -0.163 | 0.1024 | No |
| 172 | Trp53 | 12773 | -0.174 | 0.0943 | No |
| 173 | Phf5a | 13443 | -0.206 | 0.0629 | No |
| 174 | H2az1 | 13580 | -0.212 | 0.0608 | No |
| 175 | Lyar | 13789 | -0.220 | 0.0550 | No |
| 176 | Snrpb | 13823 | -0.222 | 0.0589 | No |
| 177 | Suv39h1 | 13835 | -0.223 | 0.0639 | No |
| 178 | Jpt1 | 14102 | -0.237 | 0.0554 | No |
| 179 | Ccnb2 | 14219 | -0.243 | 0.0552 | No |
| 180 | Dclre1b | 14371 | -0.252 | 0.0533 | No |
| 181 | Ppm1d | 14455 | -0.256 | 0.0553 | No |
| 182 | Pop7 | 14622 | -0.266 | 0.0530 | No |
| 183 | Mlh1 | 14715 | -0.271 | 0.0548 | No |
| 184 | Tubg1 | 14724 | -0.271 | 0.0613 | No |
| 185 | Eed | 14839 | -0.277 | 0.0621 | No |
| 186 | Pold2 | 15128 | -0.294 | 0.0538 | No |
| 187 | H2ax | 15173 | -0.296 | 0.0590 | No |
| 188 | Cdca3 | 15437 | -0.312 | 0.0525 | No |
| 189 | Nbn | 15444 | -0.312 | 0.0601 | No |
| 190 | Ing3 | 15582 | -0.321 | 0.0608 | No |
| 191 | Orc6 | 15592 | -0.322 | 0.0685 | No |
| 192 | Orc2 | 15785 | -0.334 | 0.0665 | No |
| 193 | Cdc20 | 16824 | -0.422 | 0.0203 | No |
| 194 | Myc | 16870 | -0.427 | 0.0287 | No |
| 195 | Dscc1 | 17190 | -0.461 | 0.0230 | No |
| 196 | Hmga1b | 17412 | -0.490 | 0.0234 | No |
| 197 | Prdx4 | 17674 | -0.536 | 0.0228 | No |
| 198 | Gins3 | 18146 | -0.685 | 0.0144 | No |

