| Dataset | CLP.Basophil_Pheno.cls #Group2_versus_Group3.Basophil_Pheno.cls #Group2_versus_Group3_repos |
| Phenotype | Basophil_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.49510482 |
| Normalized Enrichment Score (NES) | 1.6460155 |
| Nominal p-value | 0.060737528 |
| FDR q-value | 0.15226333 |
| FWER p-Value | 0.214 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Mcm3 | 65 | 0.793 | 0.0112 | Yes |
| 2 | Dnmt1 | 66 | 0.793 | 0.0259 | Yes |
| 3 | Brca1 | 114 | 0.730 | 0.0368 | Yes |
| 4 | Dck | 136 | 0.712 | 0.0489 | Yes |
| 5 | Psmc3ip | 140 | 0.708 | 0.0619 | Yes |
| 6 | Tcf19 | 149 | 0.702 | 0.0745 | Yes |
| 7 | Nasp | 181 | 0.677 | 0.0853 | Yes |
| 8 | Dctpp1 | 196 | 0.665 | 0.0969 | Yes |
| 9 | Mybl2 | 242 | 0.631 | 0.1061 | Yes |
| 10 | Rbbp7 | 253 | 0.624 | 0.1172 | Yes |
| 11 | Cdc25a | 260 | 0.619 | 0.1283 | Yes |
| 12 | Rpa3 | 290 | 0.602 | 0.1379 | Yes |
| 13 | Hells | 299 | 0.600 | 0.1486 | Yes |
| 14 | Prim2 | 305 | 0.597 | 0.1594 | Yes |
| 15 | Mcm4 | 345 | 0.579 | 0.1681 | Yes |
| 16 | Mcm5 | 353 | 0.576 | 0.1784 | Yes |
| 17 | Nudt21 | 386 | 0.567 | 0.1871 | Yes |
| 18 | Ran | 424 | 0.558 | 0.1954 | Yes |
| 19 | Smc1a | 447 | 0.550 | 0.2044 | Yes |
| 20 | Smc3 | 513 | 0.533 | 0.2108 | Yes |
| 21 | Rad51ap1 | 529 | 0.529 | 0.2198 | Yes |
| 22 | Lsm8 | 538 | 0.526 | 0.2291 | Yes |
| 23 | Ipo7 | 543 | 0.524 | 0.2386 | Yes |
| 24 | Pcna | 623 | 0.501 | 0.2436 | Yes |
| 25 | Ssrp1 | 625 | 0.500 | 0.2528 | Yes |
| 26 | Mcm2 | 628 | 0.499 | 0.2619 | Yes |
| 27 | Chek1 | 712 | 0.483 | 0.2663 | Yes |
| 28 | Rrm2 | 718 | 0.482 | 0.2750 | Yes |
| 29 | Donson | 760 | 0.476 | 0.2816 | Yes |
| 30 | Anp32e | 763 | 0.475 | 0.2903 | Yes |
| 31 | Srsf1 | 769 | 0.474 | 0.2988 | Yes |
| 32 | Melk | 770 | 0.474 | 0.3076 | Yes |
| 33 | Lmnb1 | 775 | 0.473 | 0.3162 | Yes |
| 34 | Psip1 | 799 | 0.470 | 0.3237 | Yes |
| 35 | Mcm6 | 878 | 0.457 | 0.3279 | Yes |
| 36 | Hnrnpd | 882 | 0.457 | 0.3362 | Yes |
| 37 | Mcm7 | 904 | 0.455 | 0.3435 | Yes |
| 38 | Atad2 | 1006 | 0.439 | 0.3461 | Yes |
| 39 | Trip13 | 1227 | 0.410 | 0.3416 | Yes |
| 40 | Cdkn1b | 1281 | 0.403 | 0.3462 | Yes |
| 41 | Timeless | 1300 | 0.400 | 0.3526 | Yes |
| 42 | Pnn | 1389 | 0.391 | 0.3551 | Yes |
| 43 | Rpa1 | 1409 | 0.389 | 0.3612 | Yes |
| 44 | Shmt1 | 1413 | 0.388 | 0.3683 | Yes |
| 45 | E2f8 | 1518 | 0.378 | 0.3696 | Yes |
| 46 | Rfc1 | 1543 | 0.376 | 0.3752 | Yes |
| 47 | Hus1 | 1550 | 0.375 | 0.3819 | Yes |
| 48 | Nolc1 | 1551 | 0.375 | 0.3888 | Yes |
| 49 | Tipin | 1595 | 0.371 | 0.3933 | Yes |
| 50 | Nap1l1 | 1669 | 0.364 | 0.3961 | Yes |
| 51 | Zw10 | 1685 | 0.362 | 0.4020 | Yes |
| 52 | Lbr | 1700 | 0.361 | 0.4079 | Yes |
| 53 | Prkdc | 1720 | 0.360 | 0.4136 | Yes |
| 54 | Dut | 1752 | 0.358 | 0.4185 | Yes |
| 55 | Spc24 | 1758 | 0.357 | 0.4249 | Yes |
| 56 | Lig1 | 1798 | 0.354 | 0.4293 | Yes |
| 57 | Pole | 1801 | 0.353 | 0.4357 | Yes |
| 58 | Ccp110 | 1905 | 0.344 | 0.4365 | Yes |
| 59 | Brca2 | 1931 | 0.342 | 0.4414 | Yes |
| 60 | Bub1b | 1960 | 0.340 | 0.4462 | Yes |
| 61 | Xpo1 | 2011 | 0.333 | 0.4497 | Yes |
| 62 | Tfrc | 2100 | 0.327 | 0.4509 | Yes |
| 63 | Nme1 | 2131 | 0.325 | 0.4553 | Yes |
| 64 | Chek2 | 2158 | 0.323 | 0.4599 | Yes |
| 65 | Nup205 | 2226 | 0.318 | 0.4621 | Yes |
| 66 | Eif2s1 | 2264 | 0.316 | 0.4659 | Yes |
| 67 | Pa2g4 | 2416 | 0.304 | 0.4633 | Yes |
| 68 | Ube2t | 2423 | 0.303 | 0.4686 | Yes |
| 69 | Nup107 | 2703 | 0.282 | 0.4585 | Yes |
| 70 | Pold3 | 2744 | 0.279 | 0.4615 | Yes |
| 71 | Msh2 | 2796 | 0.275 | 0.4638 | Yes |
| 72 | Ccne1 | 2892 | 0.269 | 0.4635 | Yes |
| 73 | Brms1l | 2935 | 0.264 | 0.4661 | Yes |
| 74 | Rpa2 | 2991 | 0.261 | 0.4680 | Yes |
| 75 | Suv39h1 | 3041 | 0.257 | 0.4700 | Yes |
| 76 | Orc6 | 3072 | 0.255 | 0.4731 | Yes |
| 77 | Paics | 3088 | 0.255 | 0.4770 | Yes |
| 78 | Aurkb | 3101 | 0.253 | 0.4811 | Yes |
| 79 | Bard1 | 3124 | 0.251 | 0.4845 | Yes |
| 80 | Cdkn2a | 3190 | 0.247 | 0.4855 | Yes |
| 81 | Nup153 | 3255 | 0.244 | 0.4866 | Yes |
| 82 | Pole4 | 3259 | 0.244 | 0.4909 | Yes |
| 83 | Slbp | 3285 | 0.242 | 0.4940 | Yes |
| 84 | Cse1l | 3392 | 0.235 | 0.4926 | Yes |
| 85 | Ubr7 | 3438 | 0.233 | 0.4944 | Yes |
| 86 | Cdkn1a | 3579 | 0.224 | 0.4909 | Yes |
| 87 | Nbn | 3617 | 0.222 | 0.4930 | Yes |
| 88 | Gins4 | 3653 | 0.219 | 0.4951 | Yes |
| 89 | Syncrip | 3985 | 0.200 | 0.4806 | No |
| 90 | Stag1 | 4115 | 0.193 | 0.4772 | No |
| 91 | Mre11a | 4184 | 0.189 | 0.4769 | No |
| 92 | Top2a | 4405 | 0.178 | 0.4681 | No |
| 93 | Cdca8 | 4461 | 0.175 | 0.4684 | No |
| 94 | Tmpo | 4533 | 0.172 | 0.4677 | No |
| 95 | Mad2l1 | 4538 | 0.171 | 0.4706 | No |
| 96 | Ncapd2 | 4634 | 0.167 | 0.4685 | No |
| 97 | Gspt1 | 4665 | 0.165 | 0.4699 | No |
| 98 | Kif22 | 4836 | 0.158 | 0.4635 | No |
| 99 | Smc6 | 4841 | 0.157 | 0.4662 | No |
| 100 | Ezh2 | 4856 | 0.157 | 0.4684 | No |
| 101 | Pola2 | 4995 | 0.152 | 0.4636 | No |
| 102 | Hmgb2 | 5068 | 0.148 | 0.4624 | No |
| 103 | Cdk1 | 5084 | 0.147 | 0.4643 | No |
| 104 | Tk1 | 5145 | 0.144 | 0.4637 | No |
| 105 | Rad50 | 5260 | 0.139 | 0.4600 | No |
| 106 | Rfc3 | 5299 | 0.137 | 0.4605 | No |
| 107 | Cbx5 | 5360 | 0.134 | 0.4596 | No |
| 108 | Aurka | 5369 | 0.133 | 0.4617 | No |
| 109 | Exosc8 | 5387 | 0.132 | 0.4632 | No |
| 110 | Ppp1r8 | 5547 | 0.126 | 0.4568 | No |
| 111 | Cdk4 | 5661 | 0.120 | 0.4528 | No |
| 112 | Tra2b | 5966 | 0.106 | 0.4381 | No |
| 113 | Ddx39a | 6003 | 0.104 | 0.4381 | No |
| 114 | Ilf3 | 6065 | 0.101 | 0.4366 | No |
| 115 | Tubb5 | 6335 | 0.090 | 0.4235 | No |
| 116 | Pttg1 | 6512 | 0.082 | 0.4153 | No |
| 117 | Mms22l | 6528 | 0.081 | 0.4160 | No |
| 118 | Dek | 6614 | 0.077 | 0.4128 | No |
| 119 | Xrcc6 | 6722 | 0.073 | 0.4083 | No |
| 120 | Dlgap5 | 6786 | 0.071 | 0.4061 | No |
| 121 | Stmn1 | 6812 | 0.070 | 0.4060 | No |
| 122 | Eed | 6818 | 0.070 | 0.4071 | No |
| 123 | Rfc2 | 6924 | 0.065 | 0.4025 | No |
| 124 | Ube2s | 6942 | 0.065 | 0.4028 | No |
| 125 | Asf1a | 6959 | 0.064 | 0.4031 | No |
| 126 | H2az1 | 6987 | 0.063 | 0.4028 | No |
| 127 | Spc25 | 7037 | 0.061 | 0.4012 | No |
| 128 | Snrpb | 7089 | 0.058 | 0.3995 | No |
| 129 | Luc7l3 | 7110 | 0.057 | 0.3995 | No |
| 130 | Ranbp1 | 7228 | 0.053 | 0.3940 | No |
| 131 | Rad51c | 7350 | 0.046 | 0.3882 | No |
| 132 | Rad1 | 7352 | 0.046 | 0.3890 | No |
| 133 | Gins1 | 7376 | 0.045 | 0.3886 | No |
| 134 | Usp1 | 7378 | 0.045 | 0.3894 | No |
| 135 | Cit | 7454 | 0.042 | 0.3860 | No |
| 136 | Pds5b | 7471 | 0.041 | 0.3859 | No |
| 137 | Rad21 | 7580 | 0.037 | 0.3807 | No |
| 138 | Kif4 | 7581 | 0.037 | 0.3814 | No |
| 139 | Ak2 | 7748 | 0.028 | 0.3728 | No |
| 140 | Racgap1 | 7808 | 0.026 | 0.3700 | No |
| 141 | Smc4 | 7811 | 0.026 | 0.3704 | No |
| 142 | Ctcf | 7987 | 0.020 | 0.3611 | No |
| 143 | Dclre1b | 8024 | 0.018 | 0.3595 | No |
| 144 | Lyar | 8325 | 0.005 | 0.3431 | No |
| 145 | Rnaseh2a | 8748 | -0.012 | 0.3201 | No |
| 146 | Tbrg4 | 8784 | -0.013 | 0.3185 | No |
| 147 | Orc2 | 8863 | -0.016 | 0.3145 | No |
| 148 | Pold1 | 9211 | -0.031 | 0.2960 | No |
| 149 | Birc5 | 9402 | -0.039 | 0.2863 | No |
| 150 | Mlh1 | 9632 | -0.047 | 0.2746 | No |
| 151 | Ung | 9894 | -0.059 | 0.2614 | No |
| 152 | Trp53 | 9976 | -0.063 | 0.2581 | No |
| 153 | Plk4 | 10008 | -0.064 | 0.2576 | No |
| 154 | Kif2c | 10072 | -0.066 | 0.2553 | No |
| 155 | Asf1b | 10387 | -0.081 | 0.2396 | No |
| 156 | Cenpe | 10423 | -0.082 | 0.2392 | No |
| 157 | Pold2 | 10430 | -0.083 | 0.2404 | No |
| 158 | Diaph3 | 10665 | -0.093 | 0.2293 | No |
| 159 | Prps1 | 10845 | -0.101 | 0.2213 | No |
| 160 | Tubg1 | 10847 | -0.101 | 0.2231 | No |
| 161 | Hmmr | 10929 | -0.105 | 0.2206 | No |
| 162 | Mki67 | 10957 | -0.106 | 0.2211 | No |
| 163 | Phf5a | 10973 | -0.106 | 0.2223 | No |
| 164 | Cnot9 | 11037 | -0.109 | 0.2208 | No |
| 165 | Hmga1b | 11172 | -0.115 | 0.2156 | No |
| 166 | Plk1 | 11382 | -0.123 | 0.2064 | No |
| 167 | Mthfd2 | 11408 | -0.125 | 0.2073 | No |
| 168 | Tacc3 | 11413 | -0.125 | 0.2095 | No |
| 169 | Cdkn2c | 11813 | -0.143 | 0.1902 | No |
| 170 | Pms2 | 11895 | -0.148 | 0.1885 | No |
| 171 | Espl1 | 12133 | -0.157 | 0.1784 | No |
| 172 | Prdx4 | 12413 | -0.172 | 0.1663 | No |
| 173 | Ing3 | 12757 | -0.189 | 0.1509 | No |
| 174 | Spag5 | 12877 | -0.195 | 0.1480 | No |
| 175 | Pop7 | 12919 | -0.197 | 0.1494 | No |
| 176 | Cks2 | 13060 | -0.206 | 0.1456 | No |
| 177 | Wdr90 | 13124 | -0.209 | 0.1460 | No |
| 178 | Pan2 | 13252 | -0.214 | 0.1430 | No |
| 179 | Myc | 13350 | -0.219 | 0.1417 | No |
| 180 | Hmgb3 | 13412 | -0.223 | 0.1425 | No |
| 181 | Nop56 | 13886 | -0.246 | 0.1211 | No |
| 182 | Cenpm | 13888 | -0.246 | 0.1256 | No |
| 183 | Depdc1a | 14124 | -0.258 | 0.1175 | No |
| 184 | Wee1 | 14218 | -0.263 | 0.1173 | No |
| 185 | H2ax | 14624 | -0.286 | 0.1003 | No |
| 186 | Srsf2 | 14707 | -0.291 | 0.1012 | No |
| 187 | Mxd3 | 15294 | -0.328 | 0.0751 | No |
| 188 | Cdkn3 | 15636 | -0.351 | 0.0629 | No |
| 189 | Gins3 | 15670 | -0.354 | 0.0677 | No |
| 190 | Cdca3 | 15861 | -0.370 | 0.0641 | No |
| 191 | Kif18b | 16068 | -0.386 | 0.0599 | No |
| 192 | Jpt1 | 16367 | -0.411 | 0.0512 | No |
| 193 | Ccnb2 | 16738 | -0.450 | 0.0393 | No |
| 194 | Cdc25b | 16880 | -0.465 | 0.0402 | No |
| 195 | Cdc20 | 17352 | -0.523 | 0.0240 | No |
| 196 | Cks1b | 17616 | -0.569 | 0.0201 | No |
| 197 | Dscc1 | 17772 | -0.600 | 0.0227 | No |
| 198 | Ppm1d | 17976 | -0.654 | 0.0237 | No |

