Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	CLP.Basophil_Pheno.cls #Group1_versus_Group4.Basophil_Pheno.cls #Group1_versus_Group4_repos
Phenotype	Basophil_Pheno.cls#Group1_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.25277168
Normalized Enrichment Score (NES)	-1.2192775
Nominal p-value	0.198
FDR q-value	0.3900674
FWER p-Value	0.922

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Sfn	325	0.643	0.0100	No
2	Plcb1	326	0.642	0.0378	No
3	Ppp2r1b	657	0.551	0.0435	No
4	Lck	768	0.525	0.0602	No
5	Pak4	888	0.502	0.0754	No
6	Traf2	1020	0.484	0.0891	No
7	Plcg1	1536	0.417	0.0790	No
8	Tsc2	1753	0.395	0.0842	No
9	Pikfyve	2078	0.368	0.0824	No
10	Smad2	2384	0.343	0.0806	No
11	Cdkn1b	2533	0.330	0.0867	No
12	Prkaa2	2665	0.325	0.0936	No
13	Akt1	3010	0.299	0.0878	No
14	Sla	3135	0.289	0.0935	No
15	Grb2	3325	0.277	0.0951	No
16	Raf1	3405	0.271	0.1025	No
17	Mknk1	3517	0.263	0.1078	No
18	Ripk1	4939	0.183	0.0380	No
19	Mapk10	4974	0.180	0.0440	No
20	Rit1	5264	0.165	0.0353	No
21	Mapk1	5307	0.164	0.0401	No
22	Pten	5330	0.162	0.0459	No
23	Rptor	5647	0.149	0.0351	No
24	Camk4	5741	0.144	0.0362	No
25	Actr3	6167	0.124	0.0184	No
26	Dapp1	6185	0.123	0.0228	No
27	Prkcb	6217	0.122	0.0263	No
28	Ube2n	6281	0.118	0.0280	No
29	Gsk3b	6345	0.116	0.0296	No
30	Itpr2	6351	0.115	0.0343	No
31	Cltc	6494	0.109	0.0312	No
32	Actr2	6645	0.101	0.0274	No
33	Rps6ka1	6897	0.090	0.0176	No
34	Vav3	7523	0.062	-0.0139	No
35	Pin1	7754	0.053	-0.0241	No
36	Ptpn11	8330	0.030	-0.0542	No
37	Akt1s1	8409	0.027	-0.0573	No
38	Ralb	8497	0.024	-0.0610	No
39	Ywhab	8506	0.024	-0.0605	No
40	Hsp90b1	8771	0.012	-0.0744	No
41	Arpc3	8949	0.005	-0.0839	No
42	Cab39	9140	-0.000	-0.0942	No
43	Gna14	9285	-0.006	-0.1018	No
44	Mapk8	9327	-0.008	-0.1037	No
45	Pla2g12a	9738	-0.025	-0.1250	No
46	Eif4e	9824	-0.029	-0.1284	No
47	Map2k6	9865	-0.030	-0.1293	No
48	Mknk2	10264	-0.047	-0.1490	No
49	Tiam1	10365	-0.052	-0.1522	No
50	Dusp3	10425	-0.055	-0.1531	No
51	Calr	10466	-0.057	-0.1528	No
52	Ube2d3	10470	-0.057	-0.1505	No
53	Mapkap1	10597	-0.062	-0.1547	No
54	Arf1	10672	-0.064	-0.1560	No
55	Grk2	10723	-0.067	-0.1558	No
56	Map3k7	10802	-0.071	-0.1570	No
57	Sqstm1	10966	-0.078	-0.1626	No
58	Atf1	10968	-0.078	-0.1593	No
59	Fasl	11103	-0.083	-0.1630	No
60	Pik3r3	11110	-0.083	-0.1597	No
61	Slc2a1	11145	-0.085	-0.1579	No
62	Cxcr4	11308	-0.093	-0.1628	No
63	Ap2m1	11459	-0.099	-0.1667	No
64	Cdk2	11478	-0.100	-0.1633	No
65	Prkar2a	11640	-0.106	-0.1675	No
66	Map2k3	11831	-0.114	-0.1730	No
67	Mapk9	11926	-0.118	-0.1730	No
68	Stat2	12020	-0.122	-0.1728	No
69	Cab39l	12584	-0.149	-0.1971	No
70	Tbk1	13604	-0.200	-0.2441	Yes
71	Egfr	13692	-0.205	-0.2400	Yes
72	Pitx2	13819	-0.208	-0.2379	Yes
73	Il4	13974	-0.218	-0.2369	Yes
74	Rps6ka3	14087	-0.223	-0.2334	Yes
75	Il2rg	14312	-0.236	-0.2355	Yes
76	Myd88	14359	-0.238	-0.2277	Yes
77	Pdk1	14702	-0.256	-0.2353	Yes
78	E2f1	14798	-0.263	-0.2291	Yes
79	Them4	14981	-0.272	-0.2273	Yes
80	Acaca	15029	-0.274	-0.2181	Yes
81	Ecsit	15253	-0.292	-0.2176	Yes
82	Tnfrsf1a	15276	-0.294	-0.2061	Yes
83	Nck1	15515	-0.308	-0.2058	Yes
84	Prkag1	16127	-0.354	-0.2239	Yes
85	Arhgdia	16287	-0.368	-0.2167	Yes
86	Adcy2	16297	-0.368	-0.2013	Yes
87	Cdkn1a	16688	-0.407	-0.2050	Yes
88	Irak4	16962	-0.437	-0.2010	Yes
89	Cdk4	17101	-0.457	-0.1888	Yes
90	Cfl1	17103	-0.457	-0.1691	Yes
91	Nfkbib	17307	-0.481	-0.1594	Yes
92	Rac1	17427	-0.503	-0.1442	Yes
93	Pfn1	17546	-0.525	-0.1280	Yes
94	Ppp1ca	17562	-0.527	-0.1061	Yes
95	Ddit3	17644	-0.543	-0.0870	Yes
96	Nod1	17681	-0.552	-0.0651	Yes
97	Trib3	17735	-0.563	-0.0437	Yes
98	Cdk1	17893	-0.597	-0.0265	Yes
99	Csnk2b	17985	-0.625	-0.0045	Yes
100	Hras	18023	-0.638	0.0210	Yes