| Dataset | CLP.Basophil_Pheno.cls #Group1_versus_Group4.Basophil_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | Basophil_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | -0.3425462 |
| Normalized Enrichment Score (NES) | -1.4785434 |
| Nominal p-value | 0.06889353 |
| FDR q-value | 0.2800232 |
| FWER p-Value | 0.445 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ak4 | 12 | 1.188 | 0.0264 | No |
| 2 | Got1 | 190 | 0.726 | 0.0332 | No |
| 3 | Sytl2 | 626 | 0.560 | 0.0220 | No |
| 4 | Fgl2 | 703 | 0.538 | 0.0301 | No |
| 5 | Serpinh1 | 999 | 0.487 | 0.0250 | No |
| 6 | Tm7sf2 | 1065 | 0.477 | 0.0323 | No |
| 7 | Hspa4 | 1331 | 0.437 | 0.0277 | No |
| 8 | Idh1 | 1716 | 0.399 | 0.0157 | No |
| 9 | Vldlr | 1921 | 0.381 | 0.0131 | No |
| 10 | Fdxr | 2424 | 0.340 | -0.0067 | No |
| 11 | Hspa9 | 2544 | 0.329 | -0.0057 | No |
| 12 | Mcm4 | 2565 | 0.328 | 0.0006 | No |
| 13 | Pitpnb | 2674 | 0.324 | 0.0021 | No |
| 14 | Mthfd2l | 3113 | 0.291 | -0.0153 | No |
| 15 | Sla | 3135 | 0.289 | -0.0099 | No |
| 16 | Btg2 | 3202 | 0.285 | -0.0070 | No |
| 17 | Atp2a2 | 3272 | 0.281 | -0.0044 | No |
| 18 | Gbe1 | 3451 | 0.267 | -0.0081 | No |
| 19 | Gpi1 | 3562 | 0.260 | -0.0082 | No |
| 20 | Hmgcs1 | 3585 | 0.259 | -0.0036 | No |
| 21 | Tfrc | 4073 | 0.228 | -0.0251 | No |
| 22 | Bhlhe40 | 4328 | 0.216 | -0.0341 | No |
| 23 | Hspd1 | 4468 | 0.211 | -0.0369 | No |
| 24 | Rrp9 | 4509 | 0.208 | -0.0344 | No |
| 25 | Asns | 4530 | 0.207 | -0.0308 | No |
| 26 | Idi1 | 4653 | 0.200 | -0.0329 | No |
| 27 | Gclc | 4810 | 0.192 | -0.0371 | No |
| 28 | Add3 | 4882 | 0.186 | -0.0368 | No |
| 29 | Ddit4 | 4961 | 0.181 | -0.0369 | No |
| 30 | Niban1 | 5072 | 0.175 | -0.0390 | No |
| 31 | Hk2 | 5218 | 0.167 | -0.0431 | No |
| 32 | Rit1 | 5264 | 0.165 | -0.0418 | No |
| 33 | Edem1 | 5322 | 0.163 | -0.0413 | No |
| 34 | Dhcr24 | 5337 | 0.162 | -0.0384 | No |
| 35 | Gmps | 5731 | 0.144 | -0.0566 | No |
| 36 | G6pdx | 5830 | 0.140 | -0.0588 | No |
| 37 | Gla | 5875 | 0.138 | -0.0581 | No |
| 38 | Ero1a | 5913 | 0.136 | -0.0570 | No |
| 39 | Actr3 | 6167 | 0.124 | -0.0681 | No |
| 40 | Dapp1 | 6185 | 0.123 | -0.0662 | No |
| 41 | Gsk3b | 6345 | 0.116 | -0.0723 | No |
| 42 | Skap2 | 6442 | 0.111 | -0.0751 | No |
| 43 | Canx | 6478 | 0.109 | -0.0745 | No |
| 44 | Actr2 | 6645 | 0.101 | -0.0813 | No |
| 45 | Hmgcr | 6802 | 0.095 | -0.0877 | No |
| 46 | Serp1 | 7015 | 0.083 | -0.0975 | No |
| 47 | M6pr | 7048 | 0.083 | -0.0973 | No |
| 48 | Gtf2h1 | 7051 | 0.083 | -0.0956 | No |
| 49 | Slc7a5 | 7076 | 0.082 | -0.0950 | No |
| 50 | Slc6a6 | 7080 | 0.082 | -0.0933 | No |
| 51 | Ccng1 | 7457 | 0.066 | -0.1125 | No |
| 52 | Acly | 7555 | 0.061 | -0.1164 | No |
| 53 | Psmc6 | 7605 | 0.059 | -0.1177 | No |
| 54 | Uso1 | 7613 | 0.059 | -0.1168 | No |
| 55 | Cdc25a | 7658 | 0.057 | -0.1179 | No |
| 56 | Slc37a4 | 7714 | 0.055 | -0.1197 | No |
| 57 | Rab1a | 7719 | 0.055 | -0.1186 | No |
| 58 | Xbp1 | 7733 | 0.054 | -0.1181 | No |
| 59 | Nfil3 | 7744 | 0.054 | -0.1174 | No |
| 60 | Psme3 | 7824 | 0.051 | -0.1206 | No |
| 61 | Psmd14 | 7965 | 0.045 | -0.1273 | No |
| 62 | Psmb5 | 8484 | 0.024 | -0.1551 | No |
| 63 | Nufip1 | 8600 | 0.020 | -0.1610 | No |
| 64 | Abcf2 | 8608 | 0.020 | -0.1609 | No |
| 65 | Immt | 8642 | 0.018 | -0.1623 | No |
| 66 | Ung | 8672 | 0.017 | -0.1635 | No |
| 67 | Hsp90b1 | 8771 | 0.012 | -0.1687 | No |
| 68 | Txnrd1 | 8836 | 0.009 | -0.1720 | No |
| 69 | Tpi1 | 8997 | 0.002 | -0.1807 | No |
| 70 | Rdh11 | 9142 | -0.000 | -0.1886 | No |
| 71 | Mcm2 | 9230 | -0.004 | -0.1933 | No |
| 72 | Wars1 | 9349 | -0.009 | -0.1996 | No |
| 73 | Adipor2 | 9433 | -0.013 | -0.2038 | No |
| 74 | Sec11a | 9469 | -0.015 | -0.2054 | No |
| 75 | Insig1 | 9548 | -0.018 | -0.2093 | No |
| 76 | Elovl5 | 9592 | -0.019 | -0.2112 | No |
| 77 | Cct6a | 9601 | -0.020 | -0.2112 | No |
| 78 | Ppp1r15a | 9765 | -0.026 | -0.2195 | No |
| 79 | Slc2a3 | 9771 | -0.027 | -0.2192 | No |
| 80 | Etf1 | 9781 | -0.027 | -0.2191 | No |
| 81 | Ufm1 | 9915 | -0.032 | -0.2257 | No |
| 82 | Stip1 | 9963 | -0.034 | -0.2275 | No |
| 83 | Cyb5b | 9976 | -0.034 | -0.2273 | No |
| 84 | Psph | 10132 | -0.041 | -0.2349 | No |
| 85 | Ccnf | 10323 | -0.049 | -0.2442 | No |
| 86 | Slc1a5 | 10333 | -0.050 | -0.2436 | No |
| 87 | Sqle | 10380 | -0.053 | -0.2449 | No |
| 88 | Bcat1 | 10415 | -0.054 | -0.2455 | No |
| 89 | Calr | 10466 | -0.057 | -0.2470 | No |
| 90 | Ube2d3 | 10470 | -0.057 | -0.2459 | No |
| 91 | Me1 | 10477 | -0.057 | -0.2449 | No |
| 92 | Ldlr | 10522 | -0.059 | -0.2460 | No |
| 93 | Gsr | 10567 | -0.061 | -0.2470 | No |
| 94 | Slc1a4 | 10599 | -0.062 | -0.2473 | No |
| 95 | Tes | 10700 | -0.066 | -0.2513 | No |
| 96 | Stard4 | 10740 | -0.068 | -0.2519 | No |
| 97 | Pgm1 | 10761 | -0.069 | -0.2514 | No |
| 98 | Prdx1 | 10762 | -0.069 | -0.2499 | No |
| 99 | Nfyc | 10843 | -0.072 | -0.2526 | No |
| 100 | Sqstm1 | 10966 | -0.078 | -0.2575 | No |
| 101 | Arpc5l | 11020 | -0.080 | -0.2586 | No |
| 102 | Nup205 | 11060 | -0.082 | -0.2589 | No |
| 103 | Tmem97 | 11096 | -0.083 | -0.2589 | No |
| 104 | Pik3r3 | 11110 | -0.083 | -0.2578 | No |
| 105 | Plk1 | 11132 | -0.084 | -0.2570 | No |
| 106 | Slc2a1 | 11145 | -0.085 | -0.2557 | No |
| 107 | Ykt6 | 11171 | -0.086 | -0.2551 | No |
| 108 | Ctsc | 11172 | -0.086 | -0.2532 | No |
| 109 | Tcea1 | 11225 | -0.089 | -0.2540 | No |
| 110 | Atp6v1d | 11256 | -0.091 | -0.2536 | No |
| 111 | Cxcr4 | 11308 | -0.093 | -0.2543 | No |
| 112 | Hmbs | 11362 | -0.096 | -0.2550 | No |
| 113 | Acsl3 | 11373 | -0.096 | -0.2534 | No |
| 114 | Eno1b | 11501 | -0.102 | -0.2580 | No |
| 115 | Psmg1 | 11646 | -0.106 | -0.2635 | No |
| 116 | Slc7a11 | 11719 | -0.109 | -0.2650 | No |
| 117 | Sord | 11793 | -0.112 | -0.2664 | No |
| 118 | Map2k3 | 11831 | -0.114 | -0.2659 | No |
| 119 | Gga2 | 12003 | -0.122 | -0.2725 | No |
| 120 | Pnp | 12033 | -0.123 | -0.2713 | No |
| 121 | Rpn1 | 12166 | -0.128 | -0.2756 | No |
| 122 | Phgdh | 12279 | -0.133 | -0.2787 | No |
| 123 | Pgk1 | 12415 | -0.141 | -0.2829 | No |
| 124 | Bub1 | 12539 | -0.147 | -0.2863 | No |
| 125 | Ssr1 | 12578 | -0.149 | -0.2850 | No |
| 126 | Elovl6 | 12583 | -0.149 | -0.2818 | No |
| 127 | Polr3g | 12886 | -0.164 | -0.2947 | No |
| 128 | Dhcr7 | 12974 | -0.169 | -0.2956 | No |
| 129 | Plod2 | 12991 | -0.169 | -0.2926 | No |
| 130 | Pno1 | 13025 | -0.171 | -0.2906 | No |
| 131 | Ppia | 13221 | -0.181 | -0.2971 | No |
| 132 | Ddx39a | 13481 | -0.193 | -0.3070 | No |
| 133 | Tbk1 | 13604 | -0.200 | -0.3091 | No |
| 134 | Lta4h | 13606 | -0.200 | -0.3046 | No |
| 135 | Aldoa | 13908 | -0.213 | -0.3163 | No |
| 136 | Fads1 | 13939 | -0.215 | -0.3130 | No |
| 137 | Cth | 13992 | -0.218 | -0.3109 | No |
| 138 | Cfp | 14012 | -0.219 | -0.3070 | No |
| 139 | Mthfd2 | 14138 | -0.225 | -0.3087 | No |
| 140 | Cacybp | 14302 | -0.235 | -0.3123 | No |
| 141 | Pdk1 | 14702 | -0.256 | -0.3284 | No |
| 142 | Lgmn | 14961 | -0.272 | -0.3364 | Yes |
| 143 | Acaca | 15029 | -0.274 | -0.3338 | Yes |
| 144 | Aurka | 15032 | -0.274 | -0.3277 | Yes |
| 145 | Psmc2 | 15064 | -0.277 | -0.3231 | Yes |
| 146 | Sc5d | 15159 | -0.284 | -0.3218 | Yes |
| 147 | Psmd13 | 15494 | -0.307 | -0.3331 | Yes |
| 148 | Eef1e1 | 15572 | -0.313 | -0.3302 | Yes |
| 149 | Cd9 | 15594 | -0.315 | -0.3242 | Yes |
| 150 | Psmc4 | 15754 | -0.326 | -0.3255 | Yes |
| 151 | Fads2 | 15759 | -0.327 | -0.3183 | Yes |
| 152 | Tomm40 | 15817 | -0.330 | -0.3139 | Yes |
| 153 | Hspe1 | 15826 | -0.331 | -0.3068 | Yes |
| 154 | Psat1 | 15840 | -0.332 | -0.3000 | Yes |
| 155 | Cops5 | 15941 | -0.340 | -0.2977 | Yes |
| 156 | Dhfr | 15943 | -0.340 | -0.2900 | Yes |
| 157 | Ifrd1 | 15989 | -0.344 | -0.2847 | Yes |
| 158 | Qdpr | 16028 | -0.346 | -0.2789 | Yes |
| 159 | Egln3 | 16054 | -0.348 | -0.2723 | Yes |
| 160 | Rpa1 | 16191 | -0.357 | -0.2717 | Yes |
| 161 | Cyp51 | 16228 | -0.361 | -0.2654 | Yes |
| 162 | Hspa5 | 16237 | -0.362 | -0.2576 | Yes |
| 163 | P4ha1 | 16303 | -0.369 | -0.2528 | Yes |
| 164 | Psmd12 | 16513 | -0.390 | -0.2554 | Yes |
| 165 | Uchl5 | 16515 | -0.390 | -0.2466 | Yes |
| 166 | Cdkn1a | 16688 | -0.407 | -0.2468 | Yes |
| 167 | Glrx | 16881 | -0.426 | -0.2476 | Yes |
| 168 | Nampt | 17004 | -0.444 | -0.2442 | Yes |
| 169 | Psma4 | 17062 | -0.452 | -0.2371 | Yes |
| 170 | Psma3 | 17066 | -0.452 | -0.2269 | Yes |
| 171 | Nfkbib | 17307 | -0.481 | -0.2292 | Yes |
| 172 | Ebp | 17353 | -0.490 | -0.2205 | Yes |
| 173 | Tuba4a | 17426 | -0.503 | -0.2130 | Yes |
| 174 | Fkbp2 | 17439 | -0.505 | -0.2022 | Yes |
| 175 | Ddit3 | 17644 | -0.543 | -0.2010 | Yes |
| 176 | Pdap1 | 17651 | -0.545 | -0.1889 | Yes |
| 177 | Coro1a | 17717 | -0.559 | -0.1798 | Yes |
| 178 | Pfkl | 17725 | -0.561 | -0.1674 | Yes |
| 179 | Eif2s2 | 17728 | -0.561 | -0.1547 | Yes |
| 180 | Trib3 | 17735 | -0.563 | -0.1423 | Yes |
| 181 | Ifi30 | 17936 | -0.611 | -0.1393 | Yes |
| 182 | Itgb2 | 17955 | -0.617 | -0.1263 | Yes |
| 183 | Srd5a1 | 18028 | -0.640 | -0.1157 | Yes |
| 184 | Rrm2 | 18041 | -0.646 | -0.1016 | Yes |
| 185 | Shmt2 | 18091 | -0.667 | -0.0892 | Yes |
| 186 | Nmt1 | 18119 | -0.677 | -0.0752 | Yes |
| 187 | Tubg1 | 18247 | -0.754 | -0.0650 | Yes |
| 188 | Ppa1 | 18249 | -0.756 | -0.0479 | Yes |
| 189 | Sdf2l1 | 18269 | -0.779 | -0.0312 | Yes |
| 190 | Ldha | 18285 | -0.795 | -0.0139 | Yes |
| 191 | Mllt11 | 18354 | -0.907 | 0.0030 | Yes |

