| Dataset | CLP.Basophil_Pheno.cls #Group1_versus_Group4.Basophil_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | Basophil_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | -0.39872873 |
| Normalized Enrichment Score (NES) | -1.3464073 |
| Nominal p-value | 0.21428572 |
| FDR q-value | 0.32871765 |
| FWER p-Value | 0.731 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Srsf1 | 988 | 0.488 | -0.0432 | No |
| 2 | Ipo7 | 1860 | 0.385 | -0.0824 | No |
| 3 | Wdr90 | 1915 | 0.381 | -0.0767 | No |
| 4 | Hnrnpd | 2212 | 0.357 | -0.0849 | No |
| 5 | Msh2 | 2228 | 0.356 | -0.0777 | No |
| 6 | Prkdc | 2265 | 0.352 | -0.0717 | No |
| 7 | Pttg1 | 2367 | 0.344 | -0.0695 | No |
| 8 | Syncrip | 2434 | 0.339 | -0.0655 | No |
| 9 | Rad21 | 2529 | 0.331 | -0.0631 | No |
| 10 | Cdkn1b | 2533 | 0.330 | -0.0558 | No |
| 11 | Mcm4 | 2565 | 0.328 | -0.0501 | No |
| 12 | Ube2s | 2616 | 0.326 | -0.0455 | No |
| 13 | Chek2 | 2695 | 0.322 | -0.0425 | No |
| 14 | Cdkn2c | 2815 | 0.313 | -0.0420 | No |
| 15 | Donson | 2846 | 0.311 | -0.0366 | No |
| 16 | Asf1b | 3018 | 0.299 | -0.0393 | No |
| 17 | Wee1 | 3449 | 0.267 | -0.0568 | No |
| 18 | Timeless | 3634 | 0.255 | -0.0612 | No |
| 19 | Cnot9 | 3817 | 0.246 | -0.0656 | No |
| 20 | Tfrc | 4073 | 0.228 | -0.0744 | No |
| 21 | Prps1 | 4724 | 0.196 | -0.1057 | No |
| 22 | Ube2t | 4837 | 0.190 | -0.1076 | No |
| 23 | Mcm3 | 4838 | 0.190 | -0.1033 | No |
| 24 | Lmnb1 | 5017 | 0.178 | -0.1090 | No |
| 25 | Rbbp7 | 5345 | 0.162 | -0.1233 | No |
| 26 | Ppm1d | 5417 | 0.158 | -0.1237 | No |
| 27 | Mlh1 | 5664 | 0.148 | -0.1338 | No |
| 28 | Pms2 | 5733 | 0.144 | -0.1343 | No |
| 29 | Srsf2 | 5778 | 0.142 | -0.1335 | No |
| 30 | Smc1a | 5931 | 0.136 | -0.1388 | No |
| 31 | Ncapd2 | 6025 | 0.132 | -0.1409 | No |
| 32 | Cse1l | 6084 | 0.128 | -0.1412 | No |
| 33 | Pnn | 6173 | 0.124 | -0.1432 | No |
| 34 | Smc3 | 6207 | 0.122 | -0.1423 | No |
| 35 | Rnaseh2a | 6313 | 0.117 | -0.1454 | No |
| 36 | Nop56 | 6853 | 0.092 | -0.1729 | No |
| 37 | Exosc8 | 6890 | 0.090 | -0.1729 | No |
| 38 | Ccp110 | 6963 | 0.086 | -0.1749 | No |
| 39 | Hells | 7103 | 0.081 | -0.1807 | No |
| 40 | Ilf3 | 7161 | 0.079 | -0.1820 | No |
| 41 | Xpo1 | 7253 | 0.074 | -0.1854 | No |
| 42 | Cks2 | 7383 | 0.069 | -0.1909 | No |
| 43 | Asf1a | 7384 | 0.069 | -0.1893 | No |
| 44 | Cdc25b | 7456 | 0.066 | -0.1917 | No |
| 45 | Pds5b | 7508 | 0.063 | -0.1931 | No |
| 46 | Hus1 | 7531 | 0.062 | -0.1929 | No |
| 47 | Cdc25a | 7658 | 0.057 | -0.1985 | No |
| 48 | Paics | 7710 | 0.055 | -0.2001 | No |
| 49 | Mcm6 | 7712 | 0.055 | -0.1989 | No |
| 50 | Ctcf | 7810 | 0.051 | -0.2030 | No |
| 51 | Rfc1 | 7914 | 0.046 | -0.2076 | No |
| 52 | Mcm5 | 7957 | 0.045 | -0.2089 | No |
| 53 | Anp32e | 8021 | 0.042 | -0.2114 | No |
| 54 | Ccnb2 | 8030 | 0.042 | -0.2109 | No |
| 55 | Melk | 8186 | 0.037 | -0.2186 | No |
| 56 | Nap1l1 | 8475 | 0.025 | -0.2339 | No |
| 57 | Spc25 | 8488 | 0.024 | -0.2340 | No |
| 58 | Trp53 | 8626 | 0.019 | -0.2411 | No |
| 59 | Ung | 8672 | 0.017 | -0.2432 | No |
| 60 | Pole | 8815 | 0.010 | -0.2507 | No |
| 61 | Atad2 | 8863 | 0.008 | -0.2531 | No |
| 62 | Mxd3 | 8880 | 0.007 | -0.2538 | No |
| 63 | Dclre1b | 8929 | 0.005 | -0.2563 | No |
| 64 | Diaph3 | 8965 | 0.004 | -0.2582 | No |
| 65 | Tra2b | 8986 | 0.002 | -0.2592 | No |
| 66 | Mcm2 | 9230 | -0.004 | -0.2725 | No |
| 67 | Eif2s1 | 9299 | -0.007 | -0.2761 | No |
| 68 | Nasp | 9333 | -0.009 | -0.2777 | No |
| 69 | Cks1b | 9369 | -0.010 | -0.2794 | No |
| 70 | Mms22l | 9393 | -0.012 | -0.2804 | No |
| 71 | Espl1 | 9538 | -0.017 | -0.2879 | No |
| 72 | Mre11a | 9774 | -0.027 | -0.3002 | No |
| 73 | Hmgb3 | 9783 | -0.027 | -0.3000 | No |
| 74 | H2ax | 9841 | -0.029 | -0.3025 | No |
| 75 | Nup153 | 9970 | -0.034 | -0.3087 | No |
| 76 | Tbrg4 | 10034 | -0.037 | -0.3113 | No |
| 77 | Prim2 | 10129 | -0.041 | -0.3156 | No |
| 78 | Luc7l3 | 10152 | -0.042 | -0.3158 | No |
| 79 | Cbx5 | 10156 | -0.042 | -0.3150 | No |
| 80 | Dlgap5 | 10207 | -0.045 | -0.3168 | No |
| 81 | Cdca8 | 10260 | -0.047 | -0.3186 | No |
| 82 | Gins4 | 10343 | -0.051 | -0.3219 | No |
| 83 | Tmpo | 10465 | -0.057 | -0.3273 | No |
| 84 | Gspt1 | 10507 | -0.058 | -0.3282 | No |
| 85 | Hmmr | 10554 | -0.060 | -0.3294 | No |
| 86 | Lbr | 10691 | -0.066 | -0.3354 | No |
| 87 | Rad1 | 10829 | -0.072 | -0.3413 | No |
| 88 | Stmn1 | 10891 | -0.074 | -0.3430 | No |
| 89 | Ing3 | 11044 | -0.081 | -0.3495 | No |
| 90 | Nup205 | 11060 | -0.082 | -0.3485 | No |
| 91 | Bub1b | 11123 | -0.084 | -0.3500 | No |
| 92 | Plk1 | 11132 | -0.084 | -0.3485 | No |
| 93 | Kif4 | 11191 | -0.087 | -0.3497 | No |
| 94 | Rad51c | 11210 | -0.088 | -0.3487 | No |
| 95 | Top2a | 11241 | -0.090 | -0.3483 | No |
| 96 | Cdkn3 | 11245 | -0.090 | -0.3465 | No |
| 97 | Pola2 | 11253 | -0.091 | -0.3448 | No |
| 98 | Kif18b | 11327 | -0.094 | -0.3467 | No |
| 99 | Smc6 | 11652 | -0.106 | -0.3621 | No |
| 100 | Dck | 11727 | -0.109 | -0.3637 | No |
| 101 | Nup107 | 11728 | -0.109 | -0.3612 | No |
| 102 | Nolc1 | 11853 | -0.115 | -0.3654 | No |
| 103 | Dnmt1 | 11962 | -0.120 | -0.3686 | No |
| 104 | Xrcc6 | 11996 | -0.121 | -0.3677 | No |
| 105 | Mcm7 | 12064 | -0.124 | -0.3686 | No |
| 106 | Kif22 | 12138 | -0.127 | -0.3697 | No |
| 107 | Myc | 12204 | -0.130 | -0.3703 | No |
| 108 | Ak2 | 12228 | -0.131 | -0.3686 | No |
| 109 | Cenpe | 12328 | -0.136 | -0.3710 | No |
| 110 | Lsm8 | 12395 | -0.140 | -0.3715 | No |
| 111 | Tubb5 | 12601 | -0.150 | -0.3793 | No |
| 112 | Stag1 | 12834 | -0.161 | -0.3884 | No |
| 113 | Pole4 | 12865 | -0.163 | -0.3864 | No |
| 114 | Depdc1a | 12882 | -0.164 | -0.3835 | No |
| 115 | Hmgb2 | 12897 | -0.165 | -0.3806 | No |
| 116 | Bard1 | 12907 | -0.166 | -0.3773 | No |
| 117 | Zw10 | 12977 | -0.169 | -0.3773 | No |
| 118 | Dscc1 | 13093 | -0.174 | -0.3797 | No |
| 119 | Pold3 | 13107 | -0.175 | -0.3764 | No |
| 120 | Brca1 | 13162 | -0.178 | -0.3754 | No |
| 121 | Orc2 | 13426 | -0.190 | -0.3855 | No |
| 122 | Smc4 | 13464 | -0.192 | -0.3832 | No |
| 123 | Ddx39a | 13481 | -0.193 | -0.3797 | No |
| 124 | Rfc2 | 13620 | -0.201 | -0.3828 | No |
| 125 | Plk4 | 13835 | -0.209 | -0.3898 | No |
| 126 | Ssrp1 | 13993 | -0.218 | -0.3935 | No |
| 127 | Cdc20 | 14089 | -0.223 | -0.3937 | Yes |
| 128 | Mybl2 | 14094 | -0.224 | -0.3888 | Yes |
| 129 | Mthfd2 | 14138 | -0.225 | -0.3861 | Yes |
| 130 | Lig1 | 14163 | -0.226 | -0.3823 | Yes |
| 131 | Tacc3 | 14212 | -0.229 | -0.3798 | Yes |
| 132 | Aurkb | 14276 | -0.233 | -0.3780 | Yes |
| 133 | Jpt1 | 14292 | -0.234 | -0.3735 | Yes |
| 134 | Ccne1 | 14338 | -0.237 | -0.3706 | Yes |
| 135 | Spag5 | 14350 | -0.238 | -0.3659 | Yes |
| 136 | Ppp1r8 | 14504 | -0.246 | -0.3687 | Yes |
| 137 | Trip13 | 14566 | -0.250 | -0.3664 | Yes |
| 138 | Brms1l | 14571 | -0.250 | -0.3610 | Yes |
| 139 | Psip1 | 14754 | -0.259 | -0.3651 | Yes |
| 140 | Dut | 14851 | -0.265 | -0.3644 | Yes |
| 141 | Aurka | 15032 | -0.274 | -0.3681 | Yes |
| 142 | Rfc3 | 15050 | -0.276 | -0.3628 | Yes |
| 143 | Brca2 | 15097 | -0.279 | -0.3590 | Yes |
| 144 | Pold2 | 15226 | -0.290 | -0.3595 | Yes |
| 145 | Suv39h1 | 15255 | -0.292 | -0.3544 | Yes |
| 146 | Lyar | 15259 | -0.293 | -0.3479 | Yes |
| 147 | Rad50 | 15278 | -0.294 | -0.3423 | Yes |
| 148 | Kif2c | 15308 | -0.295 | -0.3372 | Yes |
| 149 | Racgap1 | 15409 | -0.304 | -0.3358 | Yes |
| 150 | Cdkn2a | 15467 | -0.306 | -0.3320 | Yes |
| 151 | Rad51ap1 | 15612 | -0.316 | -0.3328 | Yes |
| 152 | Slbp | 15651 | -0.319 | -0.3277 | Yes |
| 153 | Snrpb | 15708 | -0.324 | -0.3235 | Yes |
| 154 | Pa2g4 | 15833 | -0.331 | -0.3228 | Yes |
| 155 | Psmc3ip | 15850 | -0.332 | -0.3162 | Yes |
| 156 | Gins1 | 15896 | -0.336 | -0.3110 | Yes |
| 157 | Ubr7 | 15924 | -0.339 | -0.3049 | Yes |
| 158 | Eed | 15962 | -0.342 | -0.2992 | Yes |
| 159 | Mki67 | 16005 | -0.345 | -0.2937 | Yes |
| 160 | Ezh2 | 16044 | -0.347 | -0.2879 | Yes |
| 161 | Chek1 | 16071 | -0.350 | -0.2814 | Yes |
| 162 | Hmga1b | 16083 | -0.351 | -0.2741 | Yes |
| 163 | Rpa2 | 16154 | -0.356 | -0.2699 | Yes |
| 164 | Tipin | 16179 | -0.356 | -0.2632 | Yes |
| 165 | Dek | 16182 | -0.357 | -0.2552 | Yes |
| 166 | Rpa1 | 16191 | -0.357 | -0.2476 | Yes |
| 167 | Pan2 | 16195 | -0.358 | -0.2397 | Yes |
| 168 | Cenpm | 16292 | -0.368 | -0.2367 | Yes |
| 169 | Shmt1 | 16336 | -0.370 | -0.2307 | Yes |
| 170 | Rpa3 | 16390 | -0.377 | -0.2251 | Yes |
| 171 | Usp1 | 16469 | -0.385 | -0.2206 | Yes |
| 172 | Ran | 16479 | -0.386 | -0.2124 | Yes |
| 173 | Orc6 | 16602 | -0.397 | -0.2101 | Yes |
| 174 | Cit | 16676 | -0.405 | -0.2050 | Yes |
| 175 | Cdkn1a | 16688 | -0.407 | -0.1964 | Yes |
| 176 | Ranbp1 | 16714 | -0.409 | -0.1885 | Yes |
| 177 | Dctpp1 | 16754 | -0.413 | -0.1813 | Yes |
| 178 | Pold1 | 16817 | -0.417 | -0.1753 | Yes |
| 179 | Birc5 | 16925 | -0.432 | -0.1714 | Yes |
| 180 | Mad2l1 | 16927 | -0.433 | -0.1617 | Yes |
| 181 | Cdk4 | 17101 | -0.457 | -0.1609 | Yes |
| 182 | Nudt21 | 17127 | -0.459 | -0.1519 | Yes |
| 183 | Nme1 | 17173 | -0.464 | -0.1439 | Yes |
| 184 | Gins3 | 17293 | -0.479 | -0.1396 | Yes |
| 185 | Pcna | 17478 | -0.514 | -0.1381 | Yes |
| 186 | H2az1 | 17539 | -0.523 | -0.1295 | Yes |
| 187 | E2f8 | 17561 | -0.527 | -0.1188 | Yes |
| 188 | Spc24 | 17590 | -0.533 | -0.1083 | Yes |
| 189 | Phf5a | 17601 | -0.534 | -0.0968 | Yes |
| 190 | Pop7 | 17665 | -0.548 | -0.0878 | Yes |
| 191 | Tcf19 | 17829 | -0.583 | -0.0836 | Yes |
| 192 | Cdk1 | 17893 | -0.597 | -0.0736 | Yes |
| 193 | Rrm2 | 18041 | -0.646 | -0.0671 | Yes |
| 194 | Tk1 | 18157 | -0.696 | -0.0577 | Yes |
| 195 | Tubg1 | 18247 | -0.754 | -0.0455 | Yes |
| 196 | Cdca3 | 18256 | -0.767 | -0.0286 | Yes |
| 197 | Nbn | 18262 | -0.768 | -0.0115 | Yes |
| 198 | Prdx4 | 18332 | -0.862 | 0.0042 | Yes |

