Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	CLP.Basophil_Pheno.cls #Group1_versus_Group2.Basophil_Pheno.cls #Group1_versus_Group2_repos
Phenotype	Basophil_Pheno.cls#Group1_versus_Group2_repos
Upregulated in class	1
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.33483937
Normalized Enrichment Score (NES)	-1.4665383
Nominal p-value	0.010351967
FDR q-value	0.15940455
FWER p-Value	0.444

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Dapp1	1395	0.438	-0.0558	No
2	Mapk10	1682	0.408	-0.0524	No
3	Rptor	1841	0.394	-0.0426	No
4	Prkaa2	2017	0.379	-0.0345	No
5	Tsc2	3039	0.301	-0.0762	No
6	Them4	3182	0.292	-0.0704	No
7	Sfn	3420	0.277	-0.0704	No
8	Tiam1	3440	0.276	-0.0585	No
9	Lck	3863	0.250	-0.0699	No
10	Tnfrsf1a	4438	0.220	-0.0910	No
11	Plcb1	5038	0.188	-0.1150	No
12	Gna14	5094	0.186	-0.1093	No
13	Cxcr4	5259	0.177	-0.1100	No
14	Ralb	5339	0.173	-0.1062	No
15	Sla	5475	0.167	-0.1058	No
16	Slc2a1	5612	0.160	-0.1058	No
17	Pak4	5736	0.154	-0.1053	No
18	Pin1	6012	0.140	-0.1138	No
19	Grk2	6054	0.138	-0.1096	No
20	Arpc3	6163	0.134	-0.1092	No
21	Prkcb	6215	0.132	-0.1058	No
22	Mknk2	6718	0.111	-0.1281	No
23	Itpr2	6928	0.102	-0.1348	No
24	Plcg1	6994	0.099	-0.1337	No
25	Mapk9	7014	0.098	-0.1301	No
26	Ppp2r1b	7030	0.098	-0.1264	No
27	Nfkbib	7146	0.093	-0.1283	No
28	Trib3	7294	0.086	-0.1324	No
29	Pfn1	7463	0.079	-0.1379	No
30	Cab39l	7554	0.074	-0.1393	No
31	Grb2	7667	0.070	-0.1422	No
32	Mknk1	7730	0.067	-0.1424	No
33	Ddit3	7898	0.060	-0.1487	No
34	Mapk8	7926	0.059	-0.1475	No
35	Tbk1	7968	0.057	-0.1470	No
36	Pten	8110	0.052	-0.1523	No
37	Arf1	8178	0.049	-0.1537	No
38	Ywhab	8329	0.043	-0.1599	No
39	Eif4e	8386	0.041	-0.1610	No
40	Mapk1	8448	0.040	-0.1625	No
41	Acaca	8574	0.035	-0.1677	No
42	Traf2	9175	0.010	-0.2000	No
43	Raf1	9211	0.008	-0.2015	No
44	Sqstm1	9531	-0.003	-0.2188	No
45	Ptpn11	9764	-0.012	-0.2310	No
46	Akt1s1	10376	-0.038	-0.2626	No
47	Pikfyve	10549	-0.046	-0.2698	No
48	Map2k6	10702	-0.053	-0.2756	No
49	Atf1	10918	-0.063	-0.2844	No
50	Vav3	11142	-0.071	-0.2933	No
51	Camk4	11327	-0.080	-0.2996	No
52	Pitx2	11512	-0.087	-0.3056	No
53	Rit1	11648	-0.093	-0.3086	No
54	Map3k7	11790	-0.097	-0.3118	No
55	Csnk2b	11882	-0.102	-0.3121	No
56	Mapkap1	11989	-0.107	-0.3129	No
57	Gsk3b	12048	-0.110	-0.3109	No
58	Cdk2	12212	-0.117	-0.3144	No
59	Map2k3	12213	-0.117	-0.3090	No
60	Arhgdia	12295	-0.121	-0.3077	No
61	Ripk1	12409	-0.126	-0.3080	No
62	Pla2g12a	12425	-0.127	-0.3029	No
63	Ube2n	12586	-0.134	-0.3054	No
64	Fasl	12594	-0.134	-0.2996	No
65	Rps6ka1	12816	-0.145	-0.3049	No
66	Ube2d3	12835	-0.146	-0.2990	No
67	Hras	13177	-0.162	-0.3101	No
68	Smad2	13425	-0.174	-0.3154	No
69	Prkag1	13781	-0.193	-0.3258	Yes
70	Actr3	13853	-0.197	-0.3205	Yes
71	Nck1	14003	-0.204	-0.3192	Yes
72	Hsp90b1	14183	-0.214	-0.3190	Yes
73	Ecsit	14471	-0.231	-0.3239	Yes
74	Irak4	14569	-0.237	-0.3181	Yes
75	Nod1	14636	-0.240	-0.3105	Yes
76	Actr2	15056	-0.265	-0.3211	Yes
77	Akt1	15173	-0.272	-0.3147	Yes
78	Pdk1	15224	-0.275	-0.3046	Yes
79	Cdkn1b	15371	-0.283	-0.2994	Yes
80	Cab39	15664	-0.305	-0.3011	Yes
81	Calr	15871	-0.320	-0.2974	Yes
82	Prkar2a	15896	-0.322	-0.2837	Yes
83	Stat2	16202	-0.344	-0.2843	Yes
84	Cdkn1a	16464	-0.366	-0.2815	Yes
85	Egfr	16542	-0.374	-0.2682	Yes
86	Myd88	16682	-0.387	-0.2578	Yes
87	Cltc	16747	-0.394	-0.2429	Yes
88	Ap2m1	16865	-0.407	-0.2303	Yes
89	E2f1	17009	-0.421	-0.2185	Yes
90	Rac1	17113	-0.433	-0.2039	Yes
91	Adcy2	17239	-0.450	-0.1898	Yes
92	Il4	17432	-0.477	-0.1780	Yes
93	Cdk4	17441	-0.478	-0.1561	Yes
94	Dusp3	17872	-0.558	-0.1536	Yes
95	Cfl1	17914	-0.568	-0.1293	Yes
96	Rps6ka3	18018	-0.608	-0.1066	Yes
97	Ppp1ca	18071	-0.631	-0.0800	Yes
98	Cdk1	18126	-0.659	-0.0523	Yes
99	Pik3r3	18231	-0.713	-0.0247	Yes
100	Il2rg	18264	-0.736	0.0079	Yes