| Dataset | CLP.Basophil_Pheno.cls #Group1_versus_Group2.Basophil_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | Basophil_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | -0.40694222 |
| Normalized Enrichment Score (NES) | -1.688971 |
| Nominal p-value | 0.006048387 |
| FDR q-value | 0.04421889 |
| FWER p-Value | 0.112 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ak4 | 442 | 0.615 | -0.0114 | No |
| 2 | Eef1e1 | 745 | 0.540 | -0.0168 | No |
| 3 | Btg2 | 829 | 0.524 | -0.0104 | No |
| 4 | Sytl2 | 904 | 0.511 | -0.0039 | No |
| 5 | Slc2a3 | 913 | 0.508 | 0.0063 | No |
| 6 | Got1 | 1021 | 0.489 | 0.0106 | No |
| 7 | Tmem97 | 1183 | 0.467 | 0.0115 | No |
| 8 | Dapp1 | 1395 | 0.438 | 0.0090 | No |
| 9 | Ero1a | 1443 | 0.433 | 0.0154 | No |
| 10 | Asns | 1995 | 0.381 | -0.0069 | No |
| 11 | Ebp | 2511 | 0.338 | -0.0281 | No |
| 12 | Arpc5l | 3650 | 0.262 | -0.0851 | No |
| 13 | Gclc | 3666 | 0.261 | -0.0805 | No |
| 14 | Psmb5 | 3746 | 0.257 | -0.0795 | No |
| 15 | Fdxr | 3824 | 0.253 | -0.0785 | No |
| 16 | Pgm1 | 3993 | 0.243 | -0.0826 | No |
| 17 | Slc7a5 | 4158 | 0.235 | -0.0868 | No |
| 18 | Sec11a | 4189 | 0.234 | -0.0835 | No |
| 19 | Gbe1 | 4577 | 0.213 | -0.1003 | No |
| 20 | Serpinh1 | 4613 | 0.211 | -0.0978 | No |
| 21 | Insig1 | 4681 | 0.208 | -0.0972 | No |
| 22 | Ykt6 | 4850 | 0.198 | -0.1023 | No |
| 23 | Psph | 4914 | 0.195 | -0.1017 | No |
| 24 | Idi1 | 4926 | 0.195 | -0.0982 | No |
| 25 | Phgdh | 5069 | 0.187 | -0.1021 | No |
| 26 | Psmg1 | 5219 | 0.179 | -0.1066 | No |
| 27 | Gtf2h1 | 5246 | 0.178 | -0.1043 | No |
| 28 | Cxcr4 | 5259 | 0.177 | -0.1013 | No |
| 29 | Ccng1 | 5379 | 0.171 | -0.1042 | No |
| 30 | Polr3g | 5435 | 0.169 | -0.1037 | No |
| 31 | Tes | 5452 | 0.168 | -0.1011 | No |
| 32 | Sla | 5475 | 0.167 | -0.0989 | No |
| 33 | Hk2 | 5566 | 0.162 | -0.1004 | No |
| 34 | Slc2a1 | 5612 | 0.160 | -0.0996 | No |
| 35 | Cfp | 5660 | 0.157 | -0.0989 | No |
| 36 | Psma4 | 5954 | 0.143 | -0.1120 | No |
| 37 | Ung | 5973 | 0.142 | -0.1100 | No |
| 38 | Bcat1 | 6154 | 0.135 | -0.1171 | No |
| 39 | Pitpnb | 6300 | 0.129 | -0.1224 | No |
| 40 | Pgk1 | 6574 | 0.117 | -0.1349 | No |
| 41 | Elovl5 | 6843 | 0.105 | -0.1474 | No |
| 42 | Dhcr24 | 6850 | 0.105 | -0.1456 | No |
| 43 | Mthfd2l | 6877 | 0.104 | -0.1449 | No |
| 44 | Slc37a4 | 6915 | 0.102 | -0.1448 | No |
| 45 | Atp2a2 | 7044 | 0.097 | -0.1498 | No |
| 46 | Plod2 | 7045 | 0.097 | -0.1478 | No |
| 47 | Adipor2 | 7078 | 0.096 | -0.1475 | No |
| 48 | Ppp1r15a | 7125 | 0.094 | -0.1481 | No |
| 49 | Nfkbib | 7146 | 0.093 | -0.1472 | No |
| 50 | Hspe1 | 7168 | 0.092 | -0.1465 | No |
| 51 | Wars1 | 7213 | 0.089 | -0.1470 | No |
| 52 | Cth | 7223 | 0.089 | -0.1457 | No |
| 53 | Trib3 | 7294 | 0.086 | -0.1477 | No |
| 54 | Ddit3 | 7898 | 0.060 | -0.1796 | No |
| 55 | Tbk1 | 7968 | 0.057 | -0.1822 | No |
| 56 | Psmd13 | 8557 | 0.036 | -0.2137 | No |
| 57 | Acaca | 8574 | 0.035 | -0.2139 | No |
| 58 | Slc1a4 | 8590 | 0.034 | -0.2140 | No |
| 59 | Psmd14 | 8889 | 0.021 | -0.2299 | No |
| 60 | Cdc25a | 8995 | 0.017 | -0.2353 | No |
| 61 | Tpi1 | 9003 | 0.017 | -0.2353 | No |
| 62 | Slc1a5 | 9091 | 0.013 | -0.2398 | No |
| 63 | Ifrd1 | 9197 | 0.009 | -0.2454 | No |
| 64 | Ddit4 | 9257 | 0.007 | -0.2485 | No |
| 65 | Xbp1 | 9425 | 0.000 | -0.2577 | No |
| 66 | Sqstm1 | 9531 | -0.003 | -0.2634 | No |
| 67 | Acly | 9794 | -0.013 | -0.2775 | No |
| 68 | Hmgcr | 9825 | -0.014 | -0.2789 | No |
| 69 | Fads1 | 10009 | -0.021 | -0.2885 | No |
| 70 | Dhcr7 | 10123 | -0.027 | -0.2941 | No |
| 71 | Lta4h | 10145 | -0.028 | -0.2947 | No |
| 72 | Sord | 10290 | -0.034 | -0.3019 | No |
| 73 | Psme3 | 10430 | -0.041 | -0.3087 | No |
| 74 | Eno1b | 10453 | -0.042 | -0.3090 | No |
| 75 | Fgl2 | 10504 | -0.044 | -0.3108 | No |
| 76 | Sc5d | 10827 | -0.059 | -0.3273 | No |
| 77 | Ccnf | 10840 | -0.060 | -0.3267 | No |
| 78 | Tuba4a | 10881 | -0.062 | -0.3276 | No |
| 79 | Idh1 | 11326 | -0.080 | -0.3503 | No |
| 80 | Ppia | 11378 | -0.082 | -0.3514 | No |
| 81 | Gmps | 11385 | -0.082 | -0.3500 | No |
| 82 | Coro1a | 11515 | -0.087 | -0.3553 | No |
| 83 | Slc6a6 | 11517 | -0.087 | -0.3535 | No |
| 84 | Rit1 | 11648 | -0.093 | -0.3587 | No |
| 85 | Psmc6 | 11650 | -0.093 | -0.3569 | No |
| 86 | Rrp9 | 11768 | -0.096 | -0.3613 | No |
| 87 | Gsk3b | 12048 | -0.110 | -0.3743 | No |
| 88 | Fkbp2 | 12119 | -0.113 | -0.3758 | No |
| 89 | Mthfd2 | 12188 | -0.116 | -0.3771 | No |
| 90 | Map2k3 | 12213 | -0.117 | -0.3760 | No |
| 91 | Uso1 | 12278 | -0.120 | -0.3770 | No |
| 92 | Uchl5 | 12408 | -0.126 | -0.3815 | No |
| 93 | Tcea1 | 12713 | -0.140 | -0.3953 | No |
| 94 | Ube2d3 | 12835 | -0.146 | -0.3989 | No |
| 95 | Txnrd1 | 12867 | -0.147 | -0.3975 | No |
| 96 | Rab1a | 12871 | -0.147 | -0.3946 | No |
| 97 | Bhlhe40 | 13097 | -0.158 | -0.4036 | Yes |
| 98 | Elovl6 | 13120 | -0.159 | -0.4015 | Yes |
| 99 | Rdh11 | 13125 | -0.160 | -0.3984 | Yes |
| 100 | Tomm40 | 13140 | -0.161 | -0.3959 | Yes |
| 101 | Cd9 | 13163 | -0.161 | -0.3937 | Yes |
| 102 | Hspd1 | 13185 | -0.163 | -0.3915 | Yes |
| 103 | Ldlr | 13271 | -0.167 | -0.3927 | Yes |
| 104 | Nufip1 | 13299 | -0.169 | -0.3906 | Yes |
| 105 | Nfyc | 13410 | -0.174 | -0.3931 | Yes |
| 106 | Ddx39a | 13508 | -0.179 | -0.3947 | Yes |
| 107 | Ufm1 | 13589 | -0.183 | -0.3952 | Yes |
| 108 | Cyp51 | 13639 | -0.186 | -0.3941 | Yes |
| 109 | Hspa4 | 13645 | -0.186 | -0.3905 | Yes |
| 110 | Add3 | 13654 | -0.186 | -0.3870 | Yes |
| 111 | Gpi1 | 13661 | -0.187 | -0.3835 | Yes |
| 112 | Aldoa | 13728 | -0.190 | -0.3831 | Yes |
| 113 | Pdap1 | 13771 | -0.192 | -0.3814 | Yes |
| 114 | Tm7sf2 | 13776 | -0.193 | -0.3776 | Yes |
| 115 | Psmd12 | 13787 | -0.193 | -0.3742 | Yes |
| 116 | Eif2s2 | 13794 | -0.194 | -0.3705 | Yes |
| 117 | Actr3 | 13853 | -0.197 | -0.3695 | Yes |
| 118 | Ctsc | 13907 | -0.199 | -0.3683 | Yes |
| 119 | Serp1 | 13916 | -0.199 | -0.3646 | Yes |
| 120 | Psat1 | 13969 | -0.202 | -0.3633 | Yes |
| 121 | Vldlr | 14084 | -0.208 | -0.3652 | Yes |
| 122 | Edem1 | 14150 | -0.212 | -0.3643 | Yes |
| 123 | Nampt | 14179 | -0.214 | -0.3614 | Yes |
| 124 | Hsp90b1 | 14183 | -0.214 | -0.3571 | Yes |
| 125 | Plk1 | 14434 | -0.229 | -0.3661 | Yes |
| 126 | Ssr1 | 14463 | -0.231 | -0.3628 | Yes |
| 127 | Cyb5b | 14705 | -0.244 | -0.3710 | Yes |
| 128 | Fads2 | 14737 | -0.247 | -0.3675 | Yes |
| 129 | Stip1 | 14837 | -0.253 | -0.3677 | Yes |
| 130 | Egln3 | 14943 | -0.259 | -0.3681 | Yes |
| 131 | Etf1 | 14983 | -0.262 | -0.3648 | Yes |
| 132 | M6pr | 15003 | -0.263 | -0.3603 | Yes |
| 133 | Actr2 | 15056 | -0.265 | -0.3577 | Yes |
| 134 | Prdx1 | 15215 | -0.275 | -0.3606 | Yes |
| 135 | Mcm4 | 15222 | -0.275 | -0.3552 | Yes |
| 136 | Pdk1 | 15224 | -0.275 | -0.3495 | Yes |
| 137 | Cct6a | 15258 | -0.278 | -0.3456 | Yes |
| 138 | Tfrc | 15342 | -0.281 | -0.3443 | Yes |
| 139 | Glrx | 15394 | -0.285 | -0.3411 | Yes |
| 140 | Dhfr | 15411 | -0.286 | -0.3361 | Yes |
| 141 | Atp6v1d | 15522 | -0.295 | -0.3360 | Yes |
| 142 | Niban1 | 15531 | -0.295 | -0.3302 | Yes |
| 143 | Pfkl | 15666 | -0.305 | -0.3312 | Yes |
| 144 | Nfil3 | 15672 | -0.306 | -0.3251 | Yes |
| 145 | Calr | 15871 | -0.320 | -0.3294 | Yes |
| 146 | Rpa1 | 15899 | -0.322 | -0.3241 | Yes |
| 147 | Acsl3 | 15934 | -0.324 | -0.3193 | Yes |
| 148 | Slc7a11 | 15941 | -0.324 | -0.3128 | Yes |
| 149 | Cacybp | 15991 | -0.328 | -0.3087 | Yes |
| 150 | Bub1 | 16223 | -0.347 | -0.3142 | Yes |
| 151 | G6pdx | 16235 | -0.348 | -0.3075 | Yes |
| 152 | Gga2 | 16244 | -0.348 | -0.3007 | Yes |
| 153 | Skap2 | 16257 | -0.349 | -0.2941 | Yes |
| 154 | Nup205 | 16341 | -0.356 | -0.2912 | Yes |
| 155 | Hmbs | 16395 | -0.361 | -0.2866 | Yes |
| 156 | Canx | 16433 | -0.364 | -0.2811 | Yes |
| 157 | Cdkn1a | 16464 | -0.366 | -0.2751 | Yes |
| 158 | Ldha | 16529 | -0.373 | -0.2709 | Yes |
| 159 | Immt | 16569 | -0.377 | -0.2652 | Yes |
| 160 | Psmc2 | 16596 | -0.380 | -0.2587 | Yes |
| 161 | Sdf2l1 | 16929 | -0.414 | -0.2683 | Yes |
| 162 | Qdpr | 16985 | -0.418 | -0.2626 | Yes |
| 163 | Psma3 | 17011 | -0.421 | -0.2552 | Yes |
| 164 | Hspa5 | 17107 | -0.432 | -0.2514 | Yes |
| 165 | Mcm2 | 17112 | -0.433 | -0.2426 | Yes |
| 166 | Stard4 | 17160 | -0.441 | -0.2360 | Yes |
| 167 | Cops5 | 17312 | -0.460 | -0.2347 | Yes |
| 168 | Srd5a1 | 17342 | -0.464 | -0.2267 | Yes |
| 169 | Hspa9 | 17343 | -0.464 | -0.2170 | Yes |
| 170 | Nmt1 | 17461 | -0.483 | -0.2134 | Yes |
| 171 | Pno1 | 17538 | -0.495 | -0.2072 | Yes |
| 172 | Mllt11 | 17545 | -0.496 | -0.1973 | Yes |
| 173 | Aurka | 17552 | -0.497 | -0.1872 | Yes |
| 174 | Shmt2 | 17598 | -0.503 | -0.1792 | Yes |
| 175 | Gsr | 17724 | -0.526 | -0.1751 | Yes |
| 176 | Ppa1 | 17725 | -0.526 | -0.1642 | Yes |
| 177 | Sqle | 17755 | -0.531 | -0.1547 | Yes |
| 178 | Tubg1 | 17783 | -0.538 | -0.1450 | Yes |
| 179 | P4ha1 | 17841 | -0.549 | -0.1367 | Yes |
| 180 | Abcf2 | 17879 | -0.560 | -0.1271 | Yes |
| 181 | Pnp | 17885 | -0.560 | -0.1157 | Yes |
| 182 | Hmgcs1 | 17920 | -0.570 | -0.1057 | Yes |
| 183 | Itgb2 | 18024 | -0.611 | -0.0986 | Yes |
| 184 | Rpn1 | 18091 | -0.641 | -0.0889 | Yes |
| 185 | Psmc4 | 18094 | -0.641 | -0.0756 | Yes |
| 186 | Me1 | 18095 | -0.642 | -0.0623 | Yes |
| 187 | Lgmn | 18098 | -0.643 | -0.0490 | Yes |
| 188 | Ifi30 | 18152 | -0.671 | -0.0380 | Yes |
| 189 | Pik3r3 | 18231 | -0.713 | -0.0274 | Yes |
| 190 | Gla | 18362 | -0.881 | -0.0162 | Yes |
| 191 | Rrm2 | 18371 | -0.898 | 0.0020 | Yes |

