| Dataset | CLP.Basophil_Pheno.cls #Group1_versus_Group2.Basophil_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | Basophil_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_HEME_METABOLISM |
| Enrichment Score (ES) | 0.21531667 |
| Normalized Enrichment Score (NES) | 1.1522138 |
| Nominal p-value | 0.13709678 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.942 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Arhgef12 | 90 | 0.858 | 0.0145 | Yes |
| 2 | Fbxo7 | 340 | 0.656 | 0.0158 | Yes |
| 3 | Tfdp2 | 606 | 0.568 | 0.0141 | Yes |
| 4 | Foxj2 | 689 | 0.552 | 0.0221 | Yes |
| 5 | Spta1 | 696 | 0.551 | 0.0343 | Yes |
| 6 | Hebp1 | 701 | 0.550 | 0.0466 | Yes |
| 7 | Psmd9 | 765 | 0.536 | 0.0553 | Yes |
| 8 | Btg2 | 829 | 0.524 | 0.0637 | Yes |
| 9 | Trim58 | 856 | 0.517 | 0.0740 | Yes |
| 10 | Bnip3l | 979 | 0.497 | 0.0786 | Yes |
| 11 | Dmtn | 1001 | 0.492 | 0.0886 | Yes |
| 12 | Bcam | 1006 | 0.490 | 0.0995 | Yes |
| 13 | Ezh1 | 1017 | 0.489 | 0.1100 | Yes |
| 14 | Slc11a2 | 1114 | 0.476 | 0.1156 | Yes |
| 15 | Ccdc28a | 1214 | 0.463 | 0.1206 | Yes |
| 16 | Slc6a8 | 1218 | 0.462 | 0.1309 | Yes |
| 17 | Uros | 1331 | 0.447 | 0.1349 | Yes |
| 18 | Tns1 | 1522 | 0.423 | 0.1341 | Yes |
| 19 | Slc6a9 | 1568 | 0.417 | 0.1411 | Yes |
| 20 | Tal1 | 1570 | 0.417 | 0.1505 | Yes |
| 21 | Fbxo34 | 1734 | 0.403 | 0.1507 | Yes |
| 22 | Sec14l1 | 1877 | 0.391 | 0.1518 | Yes |
| 23 | Asns | 1995 | 0.381 | 0.1540 | Yes |
| 24 | Mboat2 | 2019 | 0.379 | 0.1614 | Yes |
| 25 | Icam4 | 2070 | 0.374 | 0.1671 | Yes |
| 26 | H1f0 | 2104 | 0.371 | 0.1737 | Yes |
| 27 | Bach1 | 2117 | 0.371 | 0.1815 | Yes |
| 28 | Sidt2 | 2221 | 0.363 | 0.1840 | Yes |
| 29 | Nnt | 2293 | 0.356 | 0.1882 | Yes |
| 30 | Rcl1 | 2525 | 0.337 | 0.1832 | Yes |
| 31 | Tmcc2 | 2607 | 0.330 | 0.1862 | Yes |
| 32 | Tyr | 2668 | 0.326 | 0.1903 | Yes |
| 33 | Lrp10 | 2749 | 0.320 | 0.1932 | Yes |
| 34 | P4ha2 | 2900 | 0.311 | 0.1921 | Yes |
| 35 | Vezf1 | 2950 | 0.308 | 0.1963 | Yes |
| 36 | Gypc | 3003 | 0.303 | 0.2004 | Yes |
| 37 | Atp6v0a1 | 3119 | 0.296 | 0.2008 | Yes |
| 38 | Car1 | 3154 | 0.294 | 0.2056 | Yes |
| 39 | Pcx | 3177 | 0.292 | 0.2110 | Yes |
| 40 | Mxi1 | 3268 | 0.287 | 0.2126 | Yes |
| 41 | Aldh6a1 | 3424 | 0.277 | 0.2104 | Yes |
| 42 | Alad | 3549 | 0.269 | 0.2097 | Yes |
| 43 | Nfe2l1 | 3606 | 0.265 | 0.2126 | Yes |
| 44 | Gclc | 3666 | 0.261 | 0.2153 | Yes |
| 45 | Ucp2 | 3903 | 0.247 | 0.2080 | No |
| 46 | Khnyn | 3922 | 0.247 | 0.2126 | No |
| 47 | Foxo3 | 4030 | 0.241 | 0.2122 | No |
| 48 | Osbp2 | 4332 | 0.225 | 0.2008 | No |
| 49 | Pigq | 4460 | 0.219 | 0.1988 | No |
| 50 | Slc25a38 | 4474 | 0.218 | 0.2030 | No |
| 51 | Igsf3 | 4715 | 0.205 | 0.1945 | No |
| 52 | Kdm7a | 5037 | 0.188 | 0.1812 | No |
| 53 | Arl2bp | 5312 | 0.175 | 0.1701 | No |
| 54 | Btrc | 5316 | 0.175 | 0.1739 | No |
| 55 | Ctns | 5406 | 0.170 | 0.1729 | No |
| 56 | Slc2a1 | 5612 | 0.160 | 0.1653 | No |
| 57 | Ppox | 5626 | 0.159 | 0.1682 | No |
| 58 | Tspo2 | 5715 | 0.155 | 0.1669 | No |
| 59 | Slc22a4 | 5780 | 0.152 | 0.1668 | No |
| 60 | Rnf123 | 6245 | 0.131 | 0.1443 | No |
| 61 | Cir1 | 6429 | 0.123 | 0.1371 | No |
| 62 | Xpo7 | 6434 | 0.122 | 0.1396 | No |
| 63 | Blvra | 6613 | 0.115 | 0.1325 | No |
| 64 | Car2 | 6739 | 0.110 | 0.1281 | No |
| 65 | Epb41 | 6930 | 0.102 | 0.1200 | No |
| 66 | Htra2 | 7043 | 0.097 | 0.1161 | No |
| 67 | Klf3 | 7251 | 0.088 | 0.1067 | No |
| 68 | Marchf8 | 7256 | 0.088 | 0.1085 | No |
| 69 | Ccnd3 | 7310 | 0.086 | 0.1075 | No |
| 70 | Rhd | 7444 | 0.080 | 0.1020 | No |
| 71 | Rbm38 | 7459 | 0.079 | 0.1030 | No |
| 72 | Dcun1d1 | 7548 | 0.075 | 0.0999 | No |
| 73 | Pdzk1ip1 | 7658 | 0.070 | 0.0955 | No |
| 74 | Ell2 | 7707 | 0.068 | 0.0944 | No |
| 75 | Aldh1l1 | 7794 | 0.065 | 0.0912 | No |
| 76 | Usp15 | 7802 | 0.064 | 0.0923 | No |
| 77 | Pgls | 8068 | 0.053 | 0.0789 | No |
| 78 | Trak2 | 8103 | 0.052 | 0.0783 | No |
| 79 | Mfhas1 | 8397 | 0.041 | 0.0631 | No |
| 80 | Mkrn1 | 8425 | 0.040 | 0.0625 | No |
| 81 | Myl4 | 8471 | 0.039 | 0.0609 | No |
| 82 | Agpat4 | 8494 | 0.038 | 0.0606 | No |
| 83 | Gapvd1 | 8585 | 0.034 | 0.0564 | No |
| 84 | Daam1 | 8591 | 0.034 | 0.0569 | No |
| 85 | Kel | 8666 | 0.030 | 0.0536 | No |
| 86 | Cat | 8683 | 0.029 | 0.0533 | No |
| 87 | Fech | 8756 | 0.026 | 0.0500 | No |
| 88 | Top1 | 8806 | 0.024 | 0.0478 | No |
| 89 | Hagh | 8927 | 0.020 | 0.0417 | No |
| 90 | Gclm | 8966 | 0.018 | 0.0400 | No |
| 91 | Tnrc6b | 9024 | 0.016 | 0.0373 | No |
| 92 | Rap1gap | 9030 | 0.016 | 0.0373 | No |
| 93 | Rbm5 | 9060 | 0.014 | 0.0361 | No |
| 94 | Bmp2k | 9314 | 0.004 | 0.0223 | No |
| 95 | Sptb | 9334 | 0.004 | 0.0213 | No |
| 96 | Bpgm | 9427 | 0.000 | 0.0163 | No |
| 97 | Ctsb | 9719 | -0.010 | 0.0005 | No |
| 98 | Epor | 9957 | -0.019 | -0.0120 | No |
| 99 | Prdx2 | 10081 | -0.025 | -0.0182 | No |
| 100 | Ypel5 | 10122 | -0.027 | -0.0198 | No |
| 101 | Rad23a | 10204 | -0.030 | -0.0235 | No |
| 102 | Selenbp1 | 10243 | -0.032 | -0.0249 | No |
| 103 | Atg4a | 10350 | -0.037 | -0.0299 | No |
| 104 | Ncoa4 | 10371 | -0.038 | -0.0301 | No |
| 105 | Minpp1 | 10449 | -0.042 | -0.0334 | No |
| 106 | Slc10a3 | 10576 | -0.048 | -0.0392 | No |
| 107 | Ank1 | 10693 | -0.053 | -0.0444 | No |
| 108 | Mark3 | 10742 | -0.055 | -0.0458 | No |
| 109 | Rhag | 10945 | -0.064 | -0.0554 | No |
| 110 | Synj1 | 11002 | -0.066 | -0.0570 | No |
| 111 | Ubac1 | 11104 | -0.070 | -0.0609 | No |
| 112 | Abcb6 | 11139 | -0.071 | -0.0612 | No |
| 113 | Urod | 11191 | -0.073 | -0.0623 | No |
| 114 | Ppp2r5b | 11217 | -0.075 | -0.0620 | No |
| 115 | Glrx5 | 11283 | -0.078 | -0.0638 | No |
| 116 | Fn3k | 11350 | -0.081 | -0.0656 | No |
| 117 | Gmps | 11385 | -0.082 | -0.0656 | No |
| 118 | Tspan5 | 12022 | -0.108 | -0.0980 | No |
| 119 | Htatip2 | 12102 | -0.112 | -0.0998 | No |
| 120 | Map2k3 | 12213 | -0.117 | -0.1032 | No |
| 121 | C3 | 12249 | -0.118 | -0.1024 | No |
| 122 | Aqp3 | 12302 | -0.121 | -0.1025 | No |
| 123 | Slc4a1 | 12368 | -0.124 | -0.1033 | No |
| 124 | Optn | 12477 | -0.129 | -0.1063 | No |
| 125 | Dcaf11 | 12485 | -0.129 | -0.1037 | No |
| 126 | Endod1 | 12599 | -0.135 | -0.1069 | No |
| 127 | Tcea1 | 12713 | -0.140 | -0.1099 | No |
| 128 | Tmem9b | 12859 | -0.147 | -0.1145 | No |
| 129 | Slc66a2 | 13058 | -0.156 | -0.1218 | No |
| 130 | Cdr2 | 13276 | -0.167 | -0.1299 | No |
| 131 | Clcn3 | 13435 | -0.175 | -0.1346 | No |
| 132 | Rnf19a | 13437 | -0.175 | -0.1307 | No |
| 133 | Ctse | 13598 | -0.183 | -0.1353 | No |
| 134 | Klf1 | 13699 | -0.189 | -0.1365 | No |
| 135 | Hdgf | 13840 | -0.196 | -0.1398 | No |
| 136 | Sdcbp | 13843 | -0.196 | -0.1354 | No |
| 137 | Lmo2 | 13917 | -0.199 | -0.1349 | No |
| 138 | Snca | 14330 | -0.223 | -0.1525 | No |
| 139 | Bsg | 14406 | -0.228 | -0.1514 | No |
| 140 | Smox | 14436 | -0.229 | -0.1478 | No |
| 141 | Dcaf10 | 14442 | -0.230 | -0.1428 | No |
| 142 | Lpin2 | 14624 | -0.240 | -0.1473 | No |
| 143 | Cast | 14718 | -0.245 | -0.1469 | No |
| 144 | Fbxo9 | 14842 | -0.254 | -0.1479 | No |
| 145 | Eif2ak1 | 14844 | -0.254 | -0.1422 | No |
| 146 | Epb42 | 14980 | -0.262 | -0.1436 | No |
| 147 | Ranbp10 | 15263 | -0.278 | -0.1528 | No |
| 148 | Adipor1 | 15277 | -0.279 | -0.1472 | No |
| 149 | Mpp1 | 15284 | -0.279 | -0.1412 | No |
| 150 | Cdc27 | 15326 | -0.281 | -0.1371 | No |
| 151 | Tfrc | 15342 | -0.281 | -0.1315 | No |
| 152 | Add2 | 15347 | -0.282 | -0.1253 | No |
| 153 | Nek7 | 15387 | -0.284 | -0.1210 | No |
| 154 | Add1 | 15406 | -0.286 | -0.1155 | No |
| 155 | Nudt4 | 15528 | -0.295 | -0.1155 | No |
| 156 | Acp5 | 15937 | -0.324 | -0.1305 | No |
| 157 | Slc7a11 | 15941 | -0.324 | -0.1233 | No |
| 158 | Ermap | 16151 | -0.340 | -0.1271 | No |
| 159 | Cpox | 16153 | -0.340 | -0.1194 | No |
| 160 | Blvrb | 16217 | -0.346 | -0.1150 | No |
| 161 | Kat2b | 16290 | -0.352 | -0.1110 | No |
| 162 | Gde1 | 16292 | -0.352 | -0.1030 | No |
| 163 | Nr3c1 | 16349 | -0.357 | -0.0980 | No |
| 164 | Hmbs | 16395 | -0.361 | -0.0923 | No |
| 165 | Mospd1 | 16515 | -0.371 | -0.0904 | No |
| 166 | Gata1 | 16519 | -0.371 | -0.0821 | No |
| 167 | Narf | 16714 | -0.390 | -0.0839 | No |
| 168 | Lamp2 | 16715 | -0.390 | -0.0751 | No |
| 169 | Picalm | 16795 | -0.399 | -0.0703 | No |
| 170 | Riok3 | 16835 | -0.404 | -0.0633 | No |
| 171 | Nfe2 | 16842 | -0.405 | -0.0545 | No |
| 172 | Mocos | 17086 | -0.431 | -0.0580 | No |
| 173 | Slc30a1 | 17223 | -0.447 | -0.0553 | No |
| 174 | Abcg2 | 17305 | -0.459 | -0.0494 | No |
| 175 | Xk | 17428 | -0.476 | -0.0453 | No |
| 176 | Marchf2 | 17475 | -0.485 | -0.0368 | No |
| 177 | Alas2 | 18014 | -0.606 | -0.0526 | No |
| 178 | Mgst3 | 18159 | -0.675 | -0.0451 | No |
| 179 | Tent5c | 18177 | -0.683 | -0.0306 | No |
| 180 | E2f2 | 18378 | -0.906 | -0.0210 | No |
| 181 | Acsl6 | 18393 | -0.996 | 0.0008 | No |

