| Dataset | CLP.Basophil_Pheno.cls #Group1_versus_Group2.Basophil_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | Basophil_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | -0.44595033 |
| Normalized Enrichment Score (NES) | -1.6962821 |
| Nominal p-value | 0.06324111 |
| FDR q-value | 0.052011676 |
| FWER p-Value | 0.105 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Slc12a2 | 396 | 0.628 | -0.0068 | No |
| 2 | Ythdc1 | 2398 | 0.347 | -0.1085 | No |
| 3 | Katna1 | 2428 | 0.345 | -0.1019 | No |
| 4 | Ccnb2 | 2663 | 0.326 | -0.1070 | No |
| 5 | Myc | 3102 | 0.297 | -0.1240 | No |
| 6 | H2az2 | 3558 | 0.268 | -0.1426 | No |
| 7 | H2ax | 3681 | 0.261 | -0.1431 | No |
| 8 | Foxn3 | 3691 | 0.260 | -0.1374 | No |
| 9 | Srsf2 | 3793 | 0.254 | -0.1370 | No |
| 10 | Lig3 | 3916 | 0.247 | -0.1378 | No |
| 11 | Hmga1b | 3942 | 0.246 | -0.1333 | No |
| 12 | Ewsr1 | 4048 | 0.240 | -0.1334 | No |
| 13 | Slc7a5 | 4158 | 0.235 | -0.1338 | No |
| 14 | Odc1 | 4455 | 0.220 | -0.1449 | No |
| 15 | Cul4a | 4495 | 0.218 | -0.1418 | No |
| 16 | Mapk14 | 4500 | 0.218 | -0.1369 | No |
| 17 | Nup98 | 4703 | 0.206 | -0.1431 | No |
| 18 | Tle3 | 4851 | 0.198 | -0.1465 | No |
| 19 | Slc38a1 | 5071 | 0.187 | -0.1541 | No |
| 20 | Egf | 5142 | 0.184 | -0.1535 | No |
| 21 | Orc5 | 5349 | 0.173 | -0.1607 | No |
| 22 | Dtymk | 5354 | 0.173 | -0.1569 | No |
| 23 | Cdc20 | 5423 | 0.169 | -0.1566 | No |
| 24 | G3bp1 | 5522 | 0.164 | -0.1581 | No |
| 25 | Marcks | 5619 | 0.160 | -0.1596 | No |
| 26 | Meis2 | 5739 | 0.154 | -0.1624 | No |
| 27 | Numa1 | 5865 | 0.148 | -0.1658 | No |
| 28 | Cdkn2c | 6159 | 0.135 | -0.1787 | No |
| 29 | Gins2 | 6390 | 0.125 | -0.1884 | No |
| 30 | H2bc12 | 6629 | 0.114 | -0.1987 | No |
| 31 | Rad21 | 6812 | 0.106 | -0.2062 | No |
| 32 | Wrn | 6903 | 0.103 | -0.2087 | No |
| 33 | Hira | 6904 | 0.103 | -0.2063 | No |
| 34 | Notch2 | 6943 | 0.101 | -0.2059 | No |
| 35 | Sfpq | 7005 | 0.098 | -0.2070 | No |
| 36 | Ube2s | 7049 | 0.097 | -0.2070 | No |
| 37 | Dkc1 | 7176 | 0.092 | -0.2118 | No |
| 38 | Cks1b | 7296 | 0.086 | -0.2163 | No |
| 39 | Tra2b | 7334 | 0.085 | -0.2163 | No |
| 40 | Syncrip | 7630 | 0.071 | -0.2308 | No |
| 41 | Smad3 | 7703 | 0.069 | -0.2331 | No |
| 42 | Pola2 | 7781 | 0.066 | -0.2358 | No |
| 43 | Cdc25b | 7897 | 0.060 | -0.2407 | No |
| 44 | Map3k20 | 8001 | 0.056 | -0.2450 | No |
| 45 | Traip | 8006 | 0.056 | -0.2439 | No |
| 46 | Meis1 | 8017 | 0.056 | -0.2431 | No |
| 47 | Slc7a1 | 8130 | 0.051 | -0.2480 | No |
| 48 | Smarcc1 | 8334 | 0.043 | -0.2582 | No |
| 49 | Hif1a | 8373 | 0.042 | -0.2593 | No |
| 50 | Cdc7 | 8415 | 0.040 | -0.2606 | No |
| 51 | Pml | 8630 | 0.032 | -0.2715 | No |
| 52 | Nek2 | 8644 | 0.031 | -0.2715 | No |
| 53 | Nolc1 | 8672 | 0.030 | -0.2723 | No |
| 54 | Cul3 | 8805 | 0.024 | -0.2790 | No |
| 55 | Top1 | 8806 | 0.024 | -0.2784 | No |
| 56 | Atrx | 8892 | 0.021 | -0.2826 | No |
| 57 | Rbl1 | 8948 | 0.019 | -0.2851 | No |
| 58 | Cul1 | 8956 | 0.018 | -0.2851 | No |
| 59 | Cdc25a | 8995 | 0.017 | -0.2868 | No |
| 60 | Pttg1 | 9105 | 0.013 | -0.2925 | No |
| 61 | Hnrnpd | 9145 | 0.011 | -0.2944 | No |
| 62 | Mnat1 | 9261 | 0.006 | -0.3005 | No |
| 63 | Jpt1 | 9308 | 0.005 | -0.3029 | No |
| 64 | Rad23b | 9772 | -0.012 | -0.3281 | No |
| 65 | Pds5b | 9853 | -0.015 | -0.3321 | No |
| 66 | Kif23 | 9880 | -0.016 | -0.3331 | No |
| 67 | Pafah1b1 | 10091 | -0.025 | -0.3441 | No |
| 68 | Upf1 | 10114 | -0.026 | -0.3447 | No |
| 69 | Pura | 10209 | -0.030 | -0.3491 | No |
| 70 | Prc1 | 10222 | -0.031 | -0.3490 | No |
| 71 | Kif5b | 10339 | -0.036 | -0.3545 | No |
| 72 | Arid4a | 10401 | -0.040 | -0.3569 | No |
| 73 | E2f3 | 10532 | -0.045 | -0.3630 | No |
| 74 | Prmt5 | 10557 | -0.047 | -0.3632 | No |
| 75 | Efna5 | 10559 | -0.047 | -0.3621 | No |
| 76 | Cks2 | 10694 | -0.053 | -0.3682 | No |
| 77 | Ilf3 | 10714 | -0.054 | -0.3680 | No |
| 78 | Dbf4 | 10786 | -0.057 | -0.3706 | No |
| 79 | Ccnf | 10840 | -0.060 | -0.3721 | No |
| 80 | Suv39h1 | 11119 | -0.071 | -0.3857 | No |
| 81 | Ccnt1 | 11144 | -0.072 | -0.3853 | No |
| 82 | Fancc | 11203 | -0.074 | -0.3867 | No |
| 83 | Rasal2 | 11221 | -0.075 | -0.3859 | No |
| 84 | Srsf10 | 11247 | -0.076 | -0.3854 | No |
| 85 | Odf2 | 11277 | -0.077 | -0.3852 | No |
| 86 | Dr1 | 11281 | -0.078 | -0.3835 | No |
| 87 | Troap | 11308 | -0.079 | -0.3831 | No |
| 88 | Espl1 | 11424 | -0.084 | -0.3874 | No |
| 89 | Tacc3 | 11545 | -0.088 | -0.3919 | No |
| 90 | Hmgb3 | 11561 | -0.089 | -0.3906 | No |
| 91 | Hmmr | 11702 | -0.095 | -0.3961 | No |
| 92 | Gspt1 | 11821 | -0.099 | -0.4002 | No |
| 93 | Uck2 | 11991 | -0.107 | -0.4069 | No |
| 94 | Tfdp1 | 12002 | -0.107 | -0.4050 | No |
| 95 | Ube2c | 12462 | -0.128 | -0.4271 | No |
| 96 | Orc6 | 12498 | -0.130 | -0.4260 | No |
| 97 | Tent4a | 12644 | -0.137 | -0.4307 | No |
| 98 | Chmp1a | 12666 | -0.138 | -0.4285 | No |
| 99 | Cul5 | 12930 | -0.150 | -0.4394 | No |
| 100 | Ccnd1 | 13049 | -0.156 | -0.4422 | Yes |
| 101 | Kpnb1 | 13075 | -0.157 | -0.4398 | Yes |
| 102 | Smc4 | 13117 | -0.159 | -0.4383 | Yes |
| 103 | Rps6ka5 | 13220 | -0.165 | -0.4400 | Yes |
| 104 | Ncl | 13248 | -0.166 | -0.4376 | Yes |
| 105 | Hnrnpu | 13402 | -0.173 | -0.4418 | Yes |
| 106 | Atf5 | 13432 | -0.175 | -0.4393 | Yes |
| 107 | Cdc45 | 13460 | -0.176 | -0.4366 | Yes |
| 108 | E2f4 | 13478 | -0.177 | -0.4333 | Yes |
| 109 | Ddx39a | 13508 | -0.179 | -0.4307 | Yes |
| 110 | Tnpo2 | 13528 | -0.180 | -0.4275 | Yes |
| 111 | Abl1 | 13535 | -0.180 | -0.4235 | Yes |
| 112 | Bub3 | 13583 | -0.183 | -0.4218 | Yes |
| 113 | Prpf4b | 13646 | -0.186 | -0.4208 | Yes |
| 114 | Ctcf | 13677 | -0.187 | -0.4180 | Yes |
| 115 | Chaf1a | 13708 | -0.189 | -0.4151 | Yes |
| 116 | Kmt5a | 13761 | -0.192 | -0.4134 | Yes |
| 117 | Tgfb1 | 13847 | -0.197 | -0.4134 | Yes |
| 118 | Kif2c | 13998 | -0.204 | -0.4168 | Yes |
| 119 | Fbxo5 | 14033 | -0.205 | -0.4138 | Yes |
| 120 | Casp8ap2 | 14127 | -0.211 | -0.4139 | Yes |
| 121 | Cenpf | 14164 | -0.213 | -0.4109 | Yes |
| 122 | Kif22 | 14194 | -0.214 | -0.4074 | Yes |
| 123 | Stag1 | 14278 | -0.221 | -0.4067 | Yes |
| 124 | Knl1 | 14311 | -0.222 | -0.4032 | Yes |
| 125 | Pole | 14389 | -0.227 | -0.4020 | Yes |
| 126 | Tmpo | 14395 | -0.227 | -0.3969 | Yes |
| 127 | Ccna2 | 14396 | -0.227 | -0.3916 | Yes |
| 128 | Tpx2 | 14402 | -0.227 | -0.3864 | Yes |
| 129 | Plk4 | 14414 | -0.228 | -0.3816 | Yes |
| 130 | Plk1 | 14434 | -0.229 | -0.3772 | Yes |
| 131 | Cenpe | 14473 | -0.231 | -0.3738 | Yes |
| 132 | Cbx1 | 14515 | -0.234 | -0.3705 | Yes |
| 133 | Mcm3 | 14552 | -0.236 | -0.3669 | Yes |
| 134 | Smc1a | 14584 | -0.238 | -0.3630 | Yes |
| 135 | Mcm6 | 14592 | -0.238 | -0.3577 | Yes |
| 136 | Ss18 | 14739 | -0.247 | -0.3599 | Yes |
| 137 | Kif20b | 14841 | -0.253 | -0.3594 | Yes |
| 138 | Birc5 | 14849 | -0.254 | -0.3537 | Yes |
| 139 | Mcm5 | 14871 | -0.255 | -0.3488 | Yes |
| 140 | Sap30 | 14925 | -0.258 | -0.3456 | Yes |
| 141 | Ezh2 | 15058 | -0.265 | -0.3466 | Yes |
| 142 | Prim2 | 15119 | -0.269 | -0.3435 | Yes |
| 143 | Lmnb1 | 15131 | -0.270 | -0.3377 | Yes |
| 144 | Xpo1 | 15219 | -0.275 | -0.3360 | Yes |
| 145 | Kif4 | 15225 | -0.275 | -0.3297 | Yes |
| 146 | Srsf1 | 15266 | -0.278 | -0.3253 | Yes |
| 147 | Cdc27 | 15326 | -0.281 | -0.3219 | Yes |
| 148 | Exo1 | 15352 | -0.282 | -0.3165 | Yes |
| 149 | Cdkn1b | 15371 | -0.283 | -0.3108 | Yes |
| 150 | Nup50 | 15389 | -0.285 | -0.3050 | Yes |
| 151 | Cdkn3 | 15448 | -0.288 | -0.3013 | Yes |
| 152 | Stil | 15449 | -0.289 | -0.2945 | Yes |
| 153 | Rpa2 | 15517 | -0.295 | -0.2912 | Yes |
| 154 | Bcl3 | 15532 | -0.296 | -0.2849 | Yes |
| 155 | Nsd2 | 15787 | -0.314 | -0.2914 | Yes |
| 156 | Amd1 | 15855 | -0.318 | -0.2876 | Yes |
| 157 | H2az1 | 15859 | -0.319 | -0.2802 | Yes |
| 158 | Incenp | 15943 | -0.324 | -0.2770 | Yes |
| 159 | Racgap1 | 16036 | -0.330 | -0.2742 | Yes |
| 160 | Mtf2 | 16127 | -0.337 | -0.2712 | Yes |
| 161 | Hus1 | 16184 | -0.343 | -0.2661 | Yes |
| 162 | Bub1 | 16223 | -0.347 | -0.2600 | Yes |
| 163 | Mki67 | 16288 | -0.352 | -0.2551 | Yes |
| 164 | Top2a | 16471 | -0.367 | -0.2564 | Yes |
| 165 | Lbr | 16577 | -0.378 | -0.2532 | Yes |
| 166 | Nusap1 | 16680 | -0.387 | -0.2496 | Yes |
| 167 | Brca2 | 16687 | -0.388 | -0.2408 | Yes |
| 168 | Kif11 | 16786 | -0.398 | -0.2367 | Yes |
| 169 | Stmn1 | 16816 | -0.401 | -0.2288 | Yes |
| 170 | Cenpa | 16910 | -0.411 | -0.2241 | Yes |
| 171 | Bard1 | 16959 | -0.417 | -0.2169 | Yes |
| 172 | E2f1 | 17009 | -0.421 | -0.2096 | Yes |
| 173 | Ndc80 | 17032 | -0.423 | -0.2007 | Yes |
| 174 | Nasp | 17040 | -0.425 | -0.1910 | Yes |
| 175 | Smc2 | 17052 | -0.426 | -0.1815 | Yes |
| 176 | Mcm2 | 17112 | -0.433 | -0.1745 | Yes |
| 177 | Polq | 17224 | -0.447 | -0.1700 | Yes |
| 178 | Snrpd1 | 17392 | -0.471 | -0.1680 | Yes |
| 179 | Cdk4 | 17441 | -0.478 | -0.1593 | Yes |
| 180 | Cdc6 | 17489 | -0.487 | -0.1503 | Yes |
| 181 | Pbk | 17508 | -0.491 | -0.1396 | Yes |
| 182 | Aurka | 17552 | -0.497 | -0.1302 | Yes |
| 183 | Mybl2 | 17607 | -0.504 | -0.1212 | Yes |
| 184 | Kif15 | 17737 | -0.528 | -0.1158 | Yes |
| 185 | Sqle | 17755 | -0.531 | -0.1041 | Yes |
| 186 | Ttk | 17762 | -0.532 | -0.0918 | Yes |
| 187 | Mad2l1 | 17824 | -0.546 | -0.0822 | Yes |
| 188 | Rad54l | 17923 | -0.572 | -0.0740 | Yes |
| 189 | Dmd | 17935 | -0.576 | -0.0609 | Yes |
| 190 | Chek1 | 18058 | -0.623 | -0.0529 | Yes |
| 191 | Aurkb | 18103 | -0.645 | -0.0400 | Yes |
| 192 | Cdk1 | 18126 | -0.659 | -0.0256 | Yes |
| 193 | Hspa8 | 18342 | -0.819 | -0.0179 | Yes |
| 194 | E2f2 | 18378 | -0.906 | 0.0016 | Yes |

