Details for gene set HALLMARK_E2F

Table: GSEA Results Summary

Dataset	CLP.Basophil_Pheno.cls #Group1_versus_Group2.Basophil_Pheno.cls #Group1_versus_Group2_repos
Phenotype	Basophil_Pheno.cls#Group1_versus_Group2_repos
Upregulated in class	1
GeneSet	HALLMARK_E2F_TARGETS
Enrichment Score (ES)	-0.5489501
Normalized Enrichment Score (NES)	-1.7955217
Nominal p-value	0.018
FDR q-value	0.043664232
FWER p-Value	0.044

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Ppm1d	1387	0.439	-0.0679	No
2	Mlh1	1563	0.418	-0.0696	No
3	Dscc1	1747	0.402	-0.0721	No
4	Ccnb2	2663	0.326	-0.1161	No
5	Cnot9	2874	0.313	-0.1218	No
6	Myc	3102	0.297	-0.1286	No
7	Asf1b	3260	0.288	-0.1318	No
8	Ing3	3557	0.269	-0.1430	No
9	H2ax	3681	0.261	-0.1448	No
10	Dclre1b	3755	0.257	-0.1440	No
11	Srsf2	3793	0.254	-0.1412	No
12	Wdr90	3796	0.254	-0.1365	No
13	Hmga1b	3942	0.246	-0.1399	No
14	Trp53	4942	0.193	-0.1911	No
15	Cdc20	5423	0.169	-0.2142	No
16	Pms2	5478	0.167	-0.2140	No
17	Wee1	5832	0.149	-0.2306	No
18	Orc2	5917	0.145	-0.2325	No
19	Ung	5973	0.142	-0.2328	No
20	Cdkn2c	6159	0.135	-0.2404	No
21	Gins3	6258	0.131	-0.2433	No
22	Nop56	6328	0.127	-0.2447	No
23	Mxd3	6696	0.112	-0.2628	No
24	Mms22l	6744	0.109	-0.2633	No
25	Rad21	6812	0.106	-0.2650	No
26	Ube2s	7049	0.097	-0.2761	No
27	Chek2	7259	0.087	-0.2859	No
28	Cks1b	7296	0.086	-0.2863	No
29	Tra2b	7334	0.085	-0.2867	No
30	Rnaseh2a	7552	0.075	-0.2972	No
31	Syncrip	7630	0.071	-0.3001	No
32	Pola2	7781	0.066	-0.3071	No
33	Cdc25b	7897	0.060	-0.3123	No
34	Exosc8	8495	0.038	-0.3443	No
35	Nolc1	8672	0.030	-0.3534	No
36	Cse1l	8710	0.028	-0.3549	No
37	Diaph3	8874	0.022	-0.3635	No
38	Cdc25a	8995	0.017	-0.3698	No
39	Tbrg4	9096	0.013	-0.3750	No
40	Pttg1	9105	0.013	-0.3752	No
41	Prkdc	9120	0.012	-0.3757	No
42	Hnrnpd	9145	0.011	-0.3769	No
43	Nup153	9152	0.011	-0.3770	No
44	Jpt1	9308	0.005	-0.3854	No
45	Pds5b	9853	-0.015	-0.4150	No
46	Zw10	9929	-0.018	-0.4188	No
47	Ccp110	9939	-0.019	-0.4189	No
48	Ipo7	10479	-0.043	-0.4477	No
49	Cks2	10694	-0.053	-0.4584	No
50	Ilf3	10714	-0.054	-0.4585	No
51	Mre11a	10809	-0.058	-0.4625	No
52	Lyar	10954	-0.065	-0.4692	No
53	Eed	10978	-0.065	-0.4692	No
54	Suv39h1	11119	-0.071	-0.4756	No
55	Pold2	11132	-0.071	-0.4749	No
56	Pole4	11288	-0.078	-0.4819	No
57	Luc7l3	11295	-0.078	-0.4808	No
58	Timeless	11351	-0.081	-0.4823	No
59	Espl1	11424	-0.084	-0.4847	No
60	Kif18b	11431	-0.084	-0.4834	No
61	Snrpb	11462	-0.085	-0.4835	No
62	Rad1	11519	-0.088	-0.4849	No
63	Tacc3	11545	-0.088	-0.4846	No
64	Hmgb3	11561	-0.089	-0.4837	No
65	Hmmr	11702	-0.095	-0.4896	No
66	Gspt1	11821	-0.099	-0.4942	No
67	Smc3	12029	-0.108	-0.5036	No
68	Eif2s1	12043	-0.109	-0.5022	No
69	Pnn	12063	-0.110	-0.5012	No
70	Mthfd2	12188	-0.116	-0.5058	No
71	Orc6	12498	-0.130	-0.5203	No
72	Rad51c	12780	-0.143	-0.5330	No
73	Anp32e	12797	-0.144	-0.5312	No
74	Spag5	12882	-0.148	-0.5330	No
75	Ccne1	12892	-0.149	-0.5307	No
76	Msh2	12903	-0.149	-0.5284	No
77	Smc4	13117	-0.159	-0.5371	No
78	Tubb5	13131	-0.160	-0.5348	No
79	Rfc2	13301	-0.169	-0.5409	No
80	Xrcc6	13313	-0.169	-0.5383	No
81	Ddx39a	13508	-0.179	-0.5456	Yes
82	Depdc1a	13543	-0.180	-0.5440	Yes
83	Cbx5	13587	-0.183	-0.5429	Yes
84	Ube2t	13615	-0.184	-0.5409	Yes
85	Spc25	13671	-0.187	-0.5404	Yes
86	Ctcf	13677	-0.187	-0.5372	Yes
87	Ak2	13730	-0.190	-0.5364	Yes
88	Dek	13814	-0.194	-0.5373	Yes
89	Kif2c	13998	-0.204	-0.5435	Yes
90	Atad2	14040	-0.205	-0.5419	Yes
91	Rfc1	14056	-0.206	-0.5388	Yes
92	Kif22	14194	-0.214	-0.5423	Yes
93	Pan2	14229	-0.217	-0.5400	Yes
94	Stag1	14278	-0.221	-0.5385	Yes
95	Prps1	14302	-0.221	-0.5356	Yes
96	Pole	14389	-0.227	-0.5360	Yes
97	Tmpo	14395	-0.227	-0.5320	Yes
98	Plk4	14414	-0.228	-0.5287	Yes
99	Plk1	14434	-0.229	-0.5254	Yes
100	Cenpe	14473	-0.231	-0.5231	Yes
101	Mcm3	14552	-0.236	-0.5230	Yes
102	Smc1a	14584	-0.238	-0.5202	Yes
103	Pop7	14587	-0.238	-0.5158	Yes
104	Mcm6	14592	-0.238	-0.5115	Yes
105	Nap1l1	14593	-0.238	-0.5070	Yes
106	Pold3	14664	-0.242	-0.5063	Yes
107	Smc6	14677	-0.243	-0.5024	Yes
108	Dut	14688	-0.243	-0.4983	Yes
109	Mcm7	14743	-0.247	-0.4966	Yes
110	Paics	14768	-0.249	-0.4932	Yes
111	Birc5	14849	-0.254	-0.4928	Yes
112	Mcm5	14871	-0.255	-0.4892	Yes
113	Dlgap5	14942	-0.259	-0.4881	Yes
114	Ubr7	14969	-0.261	-0.4846	Yes
115	Ezh2	15058	-0.265	-0.4844	Yes
116	Rbbp7	15060	-0.265	-0.4795	Yes
117	Phf5a	15102	-0.268	-0.4767	Yes
118	Prim2	15119	-0.269	-0.4725	Yes
119	Lmnb1	15131	-0.270	-0.4680	Yes
120	Xpo1	15219	-0.275	-0.4676	Yes
121	Mcm4	15222	-0.275	-0.4625	Yes
122	Kif4	15225	-0.275	-0.4574	Yes
123	Usp1	15257	-0.278	-0.4539	Yes
124	Srsf1	15266	-0.278	-0.4490	Yes
125	Rad50	15287	-0.279	-0.4449	Yes
126	Hells	15290	-0.280	-0.4397	Yes
127	Tfrc	15342	-0.281	-0.4372	Yes
128	Cdkn1b	15371	-0.283	-0.4334	Yes
129	Rfc3	15395	-0.285	-0.4292	Yes
130	Cdkn3	15448	-0.288	-0.4267	Yes
131	Ncapd2	15454	-0.289	-0.4215	Yes
132	Rpa2	15517	-0.295	-0.4193	Yes
133	Cdca8	15520	-0.295	-0.4139	Yes
134	Gins1	15635	-0.303	-0.4144	Yes
135	Asf1a	15742	-0.310	-0.4144	Yes
136	Brms1l	15781	-0.313	-0.4105	Yes
137	H2az1	15859	-0.319	-0.4087	Yes
138	Pold1	15876	-0.320	-0.4036	Yes
139	Rpa1	15899	-0.322	-0.3987	Yes
140	Cenpm	15906	-0.323	-0.3929	Yes
141	Racgap1	16036	-0.330	-0.3938	Yes
142	Ranbp1	16173	-0.342	-0.3948	Yes
143	Hus1	16184	-0.343	-0.3889	Yes
144	Bub1b	16226	-0.347	-0.3845	Yes
145	Nup107	16250	-0.349	-0.3792	Yes
146	Nbn	16258	-0.350	-0.3730	Yes
147	Mki67	16288	-0.352	-0.3679	Yes
148	Donson	16318	-0.355	-0.3628	Yes
149	Nup205	16341	-0.356	-0.3573	Yes
150	Cit	16387	-0.360	-0.3530	Yes
151	Hmgb2	16459	-0.366	-0.3500	Yes
152	Cdkn1a	16464	-0.366	-0.3433	Yes
153	Top2a	16471	-0.367	-0.3367	Yes
154	Lbr	16577	-0.378	-0.3353	Yes
155	Rad51ap1	16590	-0.379	-0.3288	Yes
156	Prdx4	16659	-0.385	-0.3253	Yes
157	Brca2	16687	-0.388	-0.3194	Yes
158	Pa2g4	16777	-0.397	-0.3168	Yes
159	Stmn1	16816	-0.401	-0.3113	Yes
160	Shmt1	16824	-0.402	-0.3041	Yes
161	Ppp1r8	16853	-0.406	-0.2980	Yes
162	Brca1	16912	-0.412	-0.2934	Yes
163	Bard1	16959	-0.417	-0.2880	Yes
164	Nasp	17040	-0.425	-0.2844	Yes
165	Tcf19	17090	-0.431	-0.2790	Yes
166	Psip1	17092	-0.431	-0.2709	Yes
167	Mcm2	17112	-0.433	-0.2637	Yes
168	Nudt21	17137	-0.437	-0.2568	Yes
169	Lig1	17183	-0.444	-0.2509	Yes
170	Dctpp1	17350	-0.465	-0.2512	Yes
171	Nme1	17403	-0.473	-0.2452	Yes
172	Lsm8	17411	-0.474	-0.2366	Yes
173	Cdkn2a	17435	-0.478	-0.2288	Yes
174	Cdk4	17441	-0.478	-0.2201	Yes
175	Gins4	17479	-0.486	-0.2129	Yes
176	Aurka	17552	-0.497	-0.2075	Yes
177	Ran	17593	-0.503	-0.2002	Yes
178	Dnmt1	17599	-0.503	-0.1910	Yes
179	Mybl2	17607	-0.504	-0.1818	Yes
180	Slbp	17628	-0.508	-0.1733	Yes
181	Tk1	17711	-0.523	-0.1680	Yes
182	Pcna	17782	-0.538	-0.1616	Yes
183	Tubg1	17783	-0.538	-0.1515	Yes
184	Mad2l1	17824	-0.546	-0.1434	Yes
185	Cdca3	17871	-0.557	-0.1353	Yes
186	E2f8	17890	-0.562	-0.1257	Yes
187	Tipin	17921	-0.571	-0.1166	Yes
188	Dck	17965	-0.589	-0.1078	Yes
189	Chek1	18058	-0.623	-0.1011	Yes
190	Aurkb	18103	-0.645	-0.0914	Yes
191	Trip13	18117	-0.653	-0.0797	Yes
192	Spc24	18125	-0.659	-0.0677	Yes
193	Cdk1	18126	-0.659	-0.0552	Yes
194	Ssrp1	18196	-0.690	-0.0460	Yes
195	Melk	18218	-0.702	-0.0339	Yes
196	Psmc3ip	18238	-0.717	-0.0214	Yes
197	Rpa3	18250	-0.723	-0.0083	Yes
198	Rrm2	18371	-0.898	0.0020	Yes