Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	Basophil.Basophil_Pheno.cls #Group3_versus_Group4.Basophil_Pheno.cls #Group3_versus_Group4_repos
Phenotype	Basophil_Pheno.cls#Group3_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.36879987
Normalized Enrichment Score (NES)	-1.6815156
Nominal p-value	0.0
FDR q-value	0.1916635
FWER p-Value	0.119

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Dusp3	127	0.836	0.0350	No
2	Akt1s1	702	0.555	0.0287	No
3	Ppp2r1b	798	0.535	0.0503	No
4	Ralb	2038	0.364	-0.0058	No
5	Pak4	2528	0.317	-0.0191	No
6	Pla2g12a	2881	0.289	-0.0255	No
7	Them4	3088	0.271	-0.0241	No
8	Mknk2	3715	0.237	-0.0497	No
9	Pten	3901	0.226	-0.0494	No
10	Pin1	4015	0.218	-0.0451	No
11	Cdk1	4211	0.204	-0.0464	No
12	Prkar2a	4219	0.203	-0.0365	No
13	Eif4e	4463	0.192	-0.0413	No
14	Stat2	4605	0.183	-0.0405	No
15	Csnk2b	4894	0.166	-0.0494	No
16	Mknk1	5054	0.158	-0.0509	No
17	Ap2m1	5326	0.144	-0.0599	No
18	Mapk9	5515	0.134	-0.0644	No
19	Sfn	5658	0.126	-0.0665	No
20	Grb2	5678	0.125	-0.0612	No
21	Ecsit	5874	0.115	-0.0671	No
22	Cdkn1b	5878	0.115	-0.0614	No
23	Arf1	6516	0.083	-0.0956	No
24	Ripk1	6676	0.075	-0.1014	No
25	Slc2a1	6830	0.068	-0.1071	No
26	Gsk3b	7004	0.060	-0.1144	No
27	Mapk1	7048	0.058	-0.1141	No
28	Ppp1ca	7140	0.055	-0.1168	No
29	Rptor	7639	0.032	-0.1451	No
30	Acaca	7653	0.032	-0.1443	No
31	Sqstm1	7958	0.018	-0.1617	No
32	Smad2	8013	0.015	-0.1642	No
33	Actr2	8089	0.012	-0.1680	No
34	Grk2	8194	0.008	-0.1739	No
35	Ube2n	8218	0.007	-0.1749	No
36	Adcy2	8280	0.004	-0.1784	No
37	Lck	8512	-0.002	-0.1922	No
38	Cab39l	8692	-0.011	-0.2024	No
39	Pfn1	8693	-0.011	-0.2019	No
40	Traf2	8817	-0.016	-0.2085	No
41	Plcg1	8852	-0.018	-0.2096	No
42	Vav3	8900	-0.019	-0.2115	No
43	Map2k3	8985	-0.023	-0.2154	No
44	Cab39	9087	-0.027	-0.2201	No
45	Pikfyve	9116	-0.028	-0.2204	No
46	Map3k7	9250	-0.034	-0.2266	No
47	Cdk4	9612	-0.051	-0.2458	No
48	Map2k6	9939	-0.066	-0.2620	No
49	Ywhab	10027	-0.070	-0.2637	No
50	Prkaa2	10284	-0.082	-0.2750	No
51	Ddit3	10376	-0.086	-0.2760	No
52	Actr3	10402	-0.087	-0.2731	No
53	Dapp1	10800	-0.106	-0.2916	No
54	Tsc2	10895	-0.110	-0.2916	No
55	Itpr2	11109	-0.120	-0.2984	No
56	Cltc	11284	-0.128	-0.3023	No
57	Myd88	11287	-0.129	-0.2959	No
58	Mapkap1	11455	-0.137	-0.2989	No
59	Rps6ka1	11647	-0.145	-0.3030	No
60	Calr	11906	-0.157	-0.3106	No
61	Tnfrsf1a	12072	-0.165	-0.3121	No
62	Tbk1	12320	-0.177	-0.3179	No
63	Ube2d3	12323	-0.177	-0.3090	No
64	Arhgdia	12500	-0.188	-0.3101	No
65	Pik3r3	13231	-0.228	-0.3424	No
66	Rac1	13670	-0.255	-0.3558	Yes
67	Gna14	13829	-0.265	-0.3518	Yes
68	Cfl1	13985	-0.277	-0.3470	Yes
69	Tiam1	13992	-0.278	-0.3332	Yes
70	Camk4	14065	-0.283	-0.3231	Yes
71	Cdkn1a	14130	-0.289	-0.3122	Yes
72	Atf1	14149	-0.291	-0.2985	Yes
73	Sla	14246	-0.299	-0.2890	Yes
74	Ptpn11	14326	-0.305	-0.2783	Yes
75	Cdk2	14385	-0.308	-0.2661	Yes
76	Cxcr4	14458	-0.313	-0.2545	Yes
77	Plcb1	14585	-0.323	-0.2456	Yes
78	Mapk8	14592	-0.324	-0.2294	Yes
79	E2f1	14747	-0.336	-0.2216	Yes
80	Nfkbib	14848	-0.348	-0.2099	Yes
81	Il4	14851	-0.348	-0.1923	Yes
82	Il2rg	14949	-0.359	-0.1798	Yes
83	Rit1	14986	-0.362	-0.1635	Yes
84	Nck1	15251	-0.390	-0.1595	Yes
85	Raf1	15299	-0.397	-0.1421	Yes
86	Irak4	15329	-0.400	-0.1235	Yes
87	Rps6ka3	15439	-0.414	-0.1090	Yes
88	Hras	15452	-0.416	-0.0885	Yes
89	Akt1	15494	-0.422	-0.0694	Yes
90	Prkcb	15496	-0.422	-0.0480	Yes
91	Arpc3	15610	-0.437	-0.0325	Yes
92	Prkag1	15699	-0.449	-0.0149	Yes
93	Pdk1	15833	-0.468	0.0009	Yes
94	Nod1	15868	-0.473	0.0230	Yes
95	Hsp90b1	16159	-0.530	0.0325	Yes