| Dataset | Basophil.Basophil_Pheno.cls #Group3_versus_Group4.Basophil_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | Basophil_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_HEME_METABOLISM |
| Enrichment Score (ES) | 0.21849585 |
| Normalized Enrichment Score (NES) | 1.0961852 |
| Nominal p-value | 0.27552986 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.993 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Hmbs | 22 | 1.160 | 0.0251 | Yes |
| 2 | Xk | 146 | 0.806 | 0.0360 | Yes |
| 3 | Lmo2 | 193 | 0.766 | 0.0506 | Yes |
| 4 | Arl2bp | 227 | 0.740 | 0.0655 | Yes |
| 5 | Sptb | 264 | 0.715 | 0.0796 | Yes |
| 6 | Spta1 | 289 | 0.697 | 0.0940 | Yes |
| 7 | Ermap | 305 | 0.686 | 0.1087 | Yes |
| 8 | Nudt4 | 315 | 0.683 | 0.1237 | Yes |
| 9 | Dcaf11 | 356 | 0.655 | 0.1362 | Yes |
| 10 | Igsf3 | 436 | 0.623 | 0.1456 | Yes |
| 11 | Slc30a1 | 541 | 0.590 | 0.1527 | Yes |
| 12 | Smox | 614 | 0.574 | 0.1614 | Yes |
| 13 | Tspo2 | 617 | 0.574 | 0.1744 | Yes |
| 14 | Aldh6a1 | 661 | 0.567 | 0.1847 | Yes |
| 15 | Car1 | 869 | 0.520 | 0.1840 | Yes |
| 16 | Pcx | 930 | 0.505 | 0.1919 | Yes |
| 17 | Pgls | 1029 | 0.484 | 0.1969 | Yes |
| 18 | Gata1 | 1080 | 0.476 | 0.2047 | Yes |
| 19 | Tmcc2 | 1302 | 0.444 | 0.2015 | Yes |
| 20 | Slc6a8 | 1380 | 0.437 | 0.2068 | Yes |
| 21 | Endod1 | 1624 | 0.410 | 0.2014 | Yes |
| 22 | Tent5c | 1731 | 0.397 | 0.2040 | Yes |
| 23 | Clcn3 | 1789 | 0.392 | 0.2095 | Yes |
| 24 | Add2 | 1795 | 0.392 | 0.2181 | Yes |
| 25 | Lpin2 | 1932 | 0.377 | 0.2185 | Yes |
| 26 | Slc25a38 | 2134 | 0.353 | 0.2144 | No |
| 27 | Mboat2 | 2392 | 0.330 | 0.2063 | No |
| 28 | Foxj2 | 2462 | 0.323 | 0.2095 | No |
| 29 | Fbxo7 | 2600 | 0.311 | 0.2083 | No |
| 30 | Marchf2 | 2729 | 0.301 | 0.2074 | No |
| 31 | Epor | 2772 | 0.298 | 0.2117 | No |
| 32 | Ctns | 2909 | 0.287 | 0.2100 | No |
| 33 | Narf | 3048 | 0.274 | 0.2078 | No |
| 34 | Alad | 3177 | 0.265 | 0.2061 | No |
| 35 | Gypc | 3290 | 0.259 | 0.2052 | No |
| 36 | Ucp2 | 3494 | 0.248 | 0.1986 | No |
| 37 | Fbxo34 | 3986 | 0.220 | 0.1739 | No |
| 38 | Sidt2 | 4003 | 0.219 | 0.1779 | No |
| 39 | Sdcbp | 4089 | 0.213 | 0.1776 | No |
| 40 | Bach1 | 4124 | 0.210 | 0.1803 | No |
| 41 | Dcun1d1 | 4143 | 0.208 | 0.1840 | No |
| 42 | Foxo3 | 4473 | 0.191 | 0.1684 | No |
| 43 | Klf1 | 4513 | 0.189 | 0.1703 | No |
| 44 | Ypel5 | 4631 | 0.181 | 0.1674 | No |
| 45 | Ctsb | 4632 | 0.181 | 0.1715 | No |
| 46 | Slc11a2 | 4695 | 0.177 | 0.1718 | No |
| 47 | Mgst3 | 4776 | 0.172 | 0.1708 | No |
| 48 | Mxi1 | 4823 | 0.170 | 0.1719 | No |
| 49 | Tns1 | 4825 | 0.170 | 0.1758 | No |
| 50 | Synj1 | 4850 | 0.168 | 0.1781 | No |
| 51 | Nfe2l1 | 5096 | 0.156 | 0.1668 | No |
| 52 | Top1 | 5194 | 0.149 | 0.1644 | No |
| 53 | C3 | 5240 | 0.148 | 0.1650 | No |
| 54 | Gmps | 5357 | 0.142 | 0.1612 | No |
| 55 | Uros | 5418 | 0.139 | 0.1607 | No |
| 56 | Slc7a11 | 5499 | 0.135 | 0.1590 | No |
| 57 | Kat2b | 5680 | 0.125 | 0.1509 | No |
| 58 | Car2 | 5756 | 0.121 | 0.1491 | No |
| 59 | Gapvd1 | 5899 | 0.113 | 0.1431 | No |
| 60 | Optn | 5991 | 0.109 | 0.1401 | No |
| 61 | Ccdc28a | 6058 | 0.105 | 0.1385 | No |
| 62 | Rbm5 | 6102 | 0.104 | 0.1383 | No |
| 63 | Htatip2 | 6203 | 0.098 | 0.1344 | No |
| 64 | Gde1 | 6352 | 0.091 | 0.1276 | No |
| 65 | Psmd9 | 6387 | 0.089 | 0.1275 | No |
| 66 | Cdc27 | 6461 | 0.086 | 0.1251 | No |
| 67 | Ncoa4 | 6482 | 0.085 | 0.1258 | No |
| 68 | Pigq | 6563 | 0.080 | 0.1228 | No |
| 69 | Hdgf | 6689 | 0.074 | 0.1169 | No |
| 70 | Slc2a1 | 6830 | 0.068 | 0.1100 | No |
| 71 | Rnf19a | 6888 | 0.066 | 0.1080 | No |
| 72 | Ranbp10 | 6945 | 0.063 | 0.1061 | No |
| 73 | Picalm | 7226 | 0.051 | 0.0903 | No |
| 74 | Icam4 | 7494 | 0.038 | 0.0750 | No |
| 75 | Ezh1 | 7676 | 0.031 | 0.0647 | No |
| 76 | Vezf1 | 7777 | 0.025 | 0.0592 | No |
| 77 | Rnf123 | 7781 | 0.025 | 0.0596 | No |
| 78 | Nnt | 7788 | 0.025 | 0.0598 | No |
| 79 | Fn3k | 7823 | 0.023 | 0.0583 | No |
| 80 | Aldh1l1 | 7862 | 0.023 | 0.0565 | No |
| 81 | Rcl1 | 7924 | 0.020 | 0.0533 | No |
| 82 | Btrc | 8154 | 0.010 | 0.0396 | No |
| 83 | Hebp1 | 8182 | 0.008 | 0.0382 | No |
| 84 | Trim58 | 8198 | 0.008 | 0.0375 | No |
| 85 | Kel | 8257 | 0.005 | 0.0341 | No |
| 86 | Bpgm | 8314 | 0.002 | 0.0307 | No |
| 87 | Cpox | 8476 | -0.001 | 0.0210 | No |
| 88 | Btg2 | 8599 | -0.007 | 0.0138 | No |
| 89 | Dmtn | 8836 | -0.017 | -0.0001 | No |
| 90 | Map2k3 | 8985 | -0.023 | -0.0086 | No |
| 91 | Osbp2 | 9060 | -0.026 | -0.0124 | No |
| 92 | Fech | 9287 | -0.036 | -0.0253 | No |
| 93 | Bnip3l | 9328 | -0.039 | -0.0269 | No |
| 94 | Mark3 | 9334 | -0.039 | -0.0263 | No |
| 95 | Nfe2 | 9352 | -0.040 | -0.0264 | No |
| 96 | Minpp1 | 9401 | -0.042 | -0.0283 | No |
| 97 | Mpp1 | 9452 | -0.044 | -0.0304 | No |
| 98 | Mospd1 | 9484 | -0.046 | -0.0312 | No |
| 99 | Tnrc6b | 9520 | -0.047 | -0.0322 | No |
| 100 | Cir1 | 9811 | -0.060 | -0.0484 | No |
| 101 | Khnyn | 9894 | -0.065 | -0.0519 | No |
| 102 | Rhd | 9901 | -0.065 | -0.0508 | No |
| 103 | Nek7 | 10021 | -0.070 | -0.0564 | No |
| 104 | Urod | 10079 | -0.072 | -0.0582 | No |
| 105 | Mkrn1 | 10095 | -0.073 | -0.0575 | No |
| 106 | Ctse | 10189 | -0.078 | -0.0613 | No |
| 107 | Fbxo9 | 10199 | -0.078 | -0.0601 | No |
| 108 | Rbm38 | 10205 | -0.078 | -0.0586 | No |
| 109 | Cdr2 | 10208 | -0.078 | -0.0570 | No |
| 110 | Abcg2 | 10322 | -0.084 | -0.0619 | No |
| 111 | Atg4a | 10494 | -0.092 | -0.0702 | No |
| 112 | Eif2ak1 | 10871 | -0.109 | -0.0904 | No |
| 113 | Trak2 | 10918 | -0.111 | -0.0907 | No |
| 114 | Slc6a9 | 11006 | -0.115 | -0.0933 | No |
| 115 | Snca | 11022 | -0.116 | -0.0916 | No |
| 116 | Lrp10 | 11167 | -0.122 | -0.0975 | No |
| 117 | Slc22a4 | 11185 | -0.123 | -0.0957 | No |
| 118 | Gclm | 11217 | -0.125 | -0.0948 | No |
| 119 | Selenbp1 | 11269 | -0.128 | -0.0950 | No |
| 120 | Slc10a3 | 11447 | -0.136 | -0.1026 | No |
| 121 | Epb41 | 11521 | -0.139 | -0.1038 | No |
| 122 | Usp15 | 11530 | -0.139 | -0.1011 | No |
| 123 | Htra2 | 11574 | -0.141 | -0.1005 | No |
| 124 | Lamp2 | 11584 | -0.142 | -0.0978 | No |
| 125 | Bsg | 11715 | -0.149 | -0.1023 | No |
| 126 | H1f0 | 11720 | -0.149 | -0.0992 | No |
| 127 | Nr3c1 | 11757 | -0.151 | -0.0979 | No |
| 128 | Ppp2r5b | 11840 | -0.155 | -0.0994 | No |
| 129 | Rad23a | 11994 | -0.161 | -0.1050 | No |
| 130 | Sec14l1 | 12215 | -0.172 | -0.1144 | No |
| 131 | Ppox | 12219 | -0.172 | -0.1106 | No |
| 132 | Add1 | 12489 | -0.187 | -0.1227 | No |
| 133 | Pdzk1ip1 | 12515 | -0.189 | -0.1199 | No |
| 134 | Slc4a1 | 12524 | -0.189 | -0.1161 | No |
| 135 | Daam1 | 12576 | -0.189 | -0.1149 | No |
| 136 | Ubac1 | 12588 | -0.190 | -0.1112 | No |
| 137 | Tspan5 | 12763 | -0.200 | -0.1172 | No |
| 138 | Asns | 12789 | -0.202 | -0.1141 | No |
| 139 | Ank1 | 12840 | -0.205 | -0.1124 | No |
| 140 | Tcea1 | 12997 | -0.214 | -0.1170 | No |
| 141 | Dcaf10 | 13000 | -0.214 | -0.1123 | No |
| 142 | Tfdp2 | 13145 | -0.222 | -0.1159 | No |
| 143 | Blvra | 13163 | -0.223 | -0.1119 | No |
| 144 | E2f2 | 13182 | -0.224 | -0.1079 | No |
| 145 | Rap1gap | 13216 | -0.226 | -0.1047 | No |
| 146 | Bmp2k | 13222 | -0.227 | -0.0998 | No |
| 147 | Rhag | 13318 | -0.234 | -0.1003 | No |
| 148 | Alas2 | 13588 | -0.249 | -0.1109 | No |
| 149 | Ell2 | 13765 | -0.261 | -0.1156 | No |
| 150 | Riok3 | 13799 | -0.263 | -0.1116 | No |
| 151 | Abcb6 | 13821 | -0.265 | -0.1068 | No |
| 152 | Xpo7 | 13923 | -0.272 | -0.1068 | No |
| 153 | Glrx5 | 14029 | -0.280 | -0.1067 | No |
| 154 | Prdx2 | 14076 | -0.284 | -0.1031 | No |
| 155 | Agpat4 | 14239 | -0.299 | -0.1061 | No |
| 156 | Mfhas1 | 14271 | -0.301 | -0.1011 | No |
| 157 | Epb42 | 14475 | -0.314 | -0.1062 | No |
| 158 | Tal1 | 14525 | -0.318 | -0.1019 | No |
| 159 | Tmem9b | 14685 | -0.331 | -0.1040 | No |
| 160 | Kdm7a | 14878 | -0.350 | -0.1077 | No |
| 161 | Adipor1 | 15097 | -0.372 | -0.1124 | No |
| 162 | Ccnd3 | 15200 | -0.382 | -0.1099 | No |
| 163 | Acsl6 | 15280 | -0.394 | -0.1057 | No |
| 164 | Myl4 | 15304 | -0.398 | -0.0980 | No |
| 165 | Hagh | 15531 | -0.426 | -0.1020 | No |
| 166 | Atp6v0a1 | 15557 | -0.429 | -0.0938 | No |
| 167 | Gclc | 15706 | -0.450 | -0.0925 | No |
| 168 | Trim10 | 15745 | -0.452 | -0.0845 | No |
| 169 | Marchf8 | 15844 | -0.469 | -0.0797 | No |
| 170 | Blvrb | 15950 | -0.488 | -0.0750 | No |
| 171 | Tfrc | 16139 | -0.524 | -0.0744 | No |
| 172 | Cast | 16165 | -0.532 | -0.0638 | No |
| 173 | Arhgef12 | 16257 | -0.561 | -0.0565 | No |
| 174 | Cat | 16434 | -0.632 | -0.0528 | No |
| 175 | Mocos | 16454 | -0.645 | -0.0393 | No |
| 176 | Klf3 | 16544 | -0.709 | -0.0285 | No |
| 177 | Slc66a2 | 16556 | -0.721 | -0.0128 | No |
| 178 | Acp5 | 16674 | -0.939 | 0.0015 | No |

