| Dataset | Basophil.Basophil_Pheno.cls #Group2_versus_Group4.Basophil_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | Basophil_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | 0.28255746 |
| Normalized Enrichment Score (NES) | 1.2488894 |
| Nominal p-value | 0.18737271 |
| FDR q-value | 0.8918516 |
| FWER p-Value | 0.895 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Hmbs | 1 | 1.505 | 0.0311 | Yes |
| 2 | Ddit4 | 37 | 0.962 | 0.0489 | Yes |
| 3 | Hmgcs1 | 69 | 0.884 | 0.0654 | Yes |
| 4 | Idi1 | 85 | 0.842 | 0.0819 | Yes |
| 5 | Got1 | 191 | 0.713 | 0.0903 | Yes |
| 6 | Psat1 | 206 | 0.706 | 0.1041 | Yes |
| 7 | Acsl3 | 226 | 0.692 | 0.1172 | Yes |
| 8 | Fgl2 | 227 | 0.692 | 0.1316 | Yes |
| 9 | Hspa4 | 478 | 0.582 | 0.1285 | Yes |
| 10 | Etf1 | 498 | 0.575 | 0.1392 | Yes |
| 11 | Nupr1 | 692 | 0.529 | 0.1385 | Yes |
| 12 | Hspa9 | 841 | 0.499 | 0.1399 | Yes |
| 13 | Txnrd1 | 849 | 0.497 | 0.1498 | Yes |
| 14 | Cyp51 | 854 | 0.496 | 0.1598 | Yes |
| 15 | Nufip1 | 886 | 0.492 | 0.1681 | Yes |
| 16 | Canx | 925 | 0.484 | 0.1758 | Yes |
| 17 | Pnp | 1031 | 0.468 | 0.1792 | Yes |
| 18 | Xbp1 | 1042 | 0.467 | 0.1882 | Yes |
| 19 | Acaca | 1183 | 0.449 | 0.1891 | Yes |
| 20 | Immt | 1340 | 0.425 | 0.1884 | Yes |
| 21 | Btg2 | 1357 | 0.423 | 0.1962 | Yes |
| 22 | Mcm4 | 1450 | 0.411 | 0.1992 | Yes |
| 23 | Hspd1 | 1489 | 0.408 | 0.2053 | Yes |
| 24 | Atp6v1d | 1568 | 0.400 | 0.2089 | Yes |
| 25 | Nampt | 1571 | 0.399 | 0.2170 | Yes |
| 26 | Bhlhe40 | 1578 | 0.399 | 0.2249 | Yes |
| 27 | Nfil3 | 1632 | 0.392 | 0.2298 | Yes |
| 28 | Acly | 1846 | 0.374 | 0.2246 | Yes |
| 29 | Cct6a | 1856 | 0.373 | 0.2318 | Yes |
| 30 | Cth | 1894 | 0.370 | 0.2373 | Yes |
| 31 | Map2k3 | 1947 | 0.367 | 0.2417 | Yes |
| 32 | Ppp1r15a | 2028 | 0.357 | 0.2442 | Yes |
| 33 | Nup205 | 2040 | 0.355 | 0.2509 | Yes |
| 34 | Ykt6 | 2163 | 0.342 | 0.2506 | Yes |
| 35 | Idh1 | 2184 | 0.341 | 0.2565 | Yes |
| 36 | Slc37a4 | 2209 | 0.338 | 0.2620 | Yes |
| 37 | Gtf2h1 | 2228 | 0.336 | 0.2679 | Yes |
| 38 | Lgmn | 2487 | 0.314 | 0.2588 | Yes |
| 39 | Add3 | 2753 | 0.294 | 0.2488 | Yes |
| 40 | Hspe1 | 2809 | 0.290 | 0.2515 | Yes |
| 41 | Stip1 | 2841 | 0.286 | 0.2555 | Yes |
| 42 | Dhcr24 | 2938 | 0.278 | 0.2555 | Yes |
| 43 | Psmd13 | 3026 | 0.272 | 0.2558 | Yes |
| 44 | Cdc25a | 3053 | 0.270 | 0.2599 | Yes |
| 45 | Hsp90b1 | 3101 | 0.266 | 0.2625 | Yes |
| 46 | Aldoa | 3277 | 0.254 | 0.2572 | Yes |
| 47 | Cd9 | 3338 | 0.249 | 0.2587 | Yes |
| 48 | Sc5d | 3405 | 0.244 | 0.2598 | Yes |
| 49 | Slc2a3 | 3590 | 0.231 | 0.2534 | Yes |
| 50 | Abcf2 | 3608 | 0.229 | 0.2571 | Yes |
| 51 | Asns | 3617 | 0.228 | 0.2614 | Yes |
| 52 | Ctsc | 3641 | 0.226 | 0.2646 | Yes |
| 53 | Itgb2 | 3658 | 0.225 | 0.2683 | Yes |
| 54 | Sord | 3660 | 0.225 | 0.2729 | Yes |
| 55 | Ak4 | 3694 | 0.222 | 0.2755 | Yes |
| 56 | Atp2a2 | 3749 | 0.219 | 0.2768 | Yes |
| 57 | Bcat1 | 3804 | 0.215 | 0.2780 | Yes |
| 58 | Actr2 | 3823 | 0.215 | 0.2813 | Yes |
| 59 | Calr | 3876 | 0.211 | 0.2826 | Yes |
| 60 | Aurka | 4127 | 0.195 | 0.2714 | No |
| 61 | Hspa5 | 4240 | 0.187 | 0.2685 | No |
| 62 | Tes | 4357 | 0.179 | 0.2652 | No |
| 63 | Tomm40 | 4361 | 0.179 | 0.2687 | No |
| 64 | Ssr1 | 4420 | 0.176 | 0.2689 | No |
| 65 | Psmd14 | 4526 | 0.170 | 0.2660 | No |
| 66 | Slc1a4 | 4558 | 0.169 | 0.2677 | No |
| 67 | Insig1 | 4701 | 0.165 | 0.2625 | No |
| 68 | Gla | 4739 | 0.162 | 0.2636 | No |
| 69 | Actr3 | 4744 | 0.162 | 0.2667 | No |
| 70 | Nfyc | 4822 | 0.157 | 0.2653 | No |
| 71 | Nfkbib | 4890 | 0.154 | 0.2644 | No |
| 72 | Psmc4 | 4957 | 0.150 | 0.2635 | No |
| 73 | Mcm2 | 5126 | 0.141 | 0.2563 | No |
| 74 | M6pr | 5178 | 0.138 | 0.2560 | No |
| 75 | Rab1a | 5350 | 0.128 | 0.2483 | No |
| 76 | Ero1a | 5365 | 0.128 | 0.2501 | No |
| 77 | Srd5a1 | 5645 | 0.113 | 0.2356 | No |
| 78 | Pitpnb | 5656 | 0.113 | 0.2373 | No |
| 79 | Ung | 5731 | 0.109 | 0.2351 | No |
| 80 | Rpn1 | 5737 | 0.109 | 0.2370 | No |
| 81 | Elovl6 | 5824 | 0.104 | 0.2340 | No |
| 82 | Plod2 | 5883 | 0.101 | 0.2326 | No |
| 83 | Uso1 | 5991 | 0.096 | 0.2281 | No |
| 84 | Ifrd1 | 6093 | 0.091 | 0.2238 | No |
| 85 | Dhfr | 6289 | 0.081 | 0.2137 | No |
| 86 | Hk2 | 6327 | 0.078 | 0.2131 | No |
| 87 | Skap2 | 6482 | 0.072 | 0.2053 | No |
| 88 | Psme3 | 6551 | 0.068 | 0.2026 | No |
| 89 | Gpi1 | 6599 | 0.066 | 0.2011 | No |
| 90 | Stard4 | 6623 | 0.065 | 0.2010 | No |
| 91 | Rrm2 | 6688 | 0.061 | 0.1984 | No |
| 92 | Ccnf | 6693 | 0.061 | 0.1994 | No |
| 93 | Rpa1 | 6786 | 0.056 | 0.1950 | No |
| 94 | Pfkl | 6881 | 0.050 | 0.1904 | No |
| 95 | Gsr | 6972 | 0.046 | 0.1859 | No |
| 96 | Phgdh | 6979 | 0.046 | 0.1865 | No |
| 97 | Eno1b | 7084 | 0.041 | 0.1810 | No |
| 98 | Gclc | 7218 | 0.033 | 0.1736 | No |
| 99 | Edem1 | 7316 | 0.028 | 0.1683 | No |
| 100 | Sec11a | 7332 | 0.027 | 0.1680 | No |
| 101 | Tfrc | 7337 | 0.027 | 0.1683 | No |
| 102 | Ube2d3 | 7408 | 0.023 | 0.1646 | No |
| 103 | Slc6a6 | 7632 | 0.013 | 0.1513 | No |
| 104 | Cyb5b | 7635 | 0.012 | 0.1514 | No |
| 105 | Rit1 | 7663 | 0.011 | 0.1500 | No |
| 106 | Fads2 | 7673 | 0.010 | 0.1497 | No |
| 107 | Sqle | 7773 | 0.006 | 0.1438 | No |
| 108 | Bub1 | 7786 | 0.005 | 0.1432 | No |
| 109 | Gbe1 | 7835 | 0.003 | 0.1404 | No |
| 110 | Ldlr | 7958 | -0.001 | 0.1330 | No |
| 111 | Pgm1 | 7959 | -0.001 | 0.1330 | No |
| 112 | Sytl2 | 7970 | -0.001 | 0.1324 | No |
| 113 | P4ha1 | 8227 | -0.012 | 0.1171 | No |
| 114 | Glrx | 8257 | -0.013 | 0.1157 | No |
| 115 | Psma3 | 8375 | -0.018 | 0.1089 | No |
| 116 | Mthfd2l | 8452 | -0.021 | 0.1048 | No |
| 117 | Slc7a11 | 8750 | -0.035 | 0.0875 | No |
| 118 | Rrp9 | 8760 | -0.036 | 0.0877 | No |
| 119 | Serp1 | 8794 | -0.037 | 0.0865 | No |
| 120 | Ddx39a | 8798 | -0.037 | 0.0871 | No |
| 121 | Fads1 | 8876 | -0.040 | 0.0832 | No |
| 122 | Psmg1 | 8988 | -0.044 | 0.0774 | No |
| 123 | Slc7a5 | 9002 | -0.044 | 0.0775 | No |
| 124 | Psmd12 | 9031 | -0.046 | 0.0768 | No |
| 125 | Qdpr | 9121 | -0.049 | 0.0724 | No |
| 126 | Gmps | 9185 | -0.052 | 0.0697 | No |
| 127 | Niban1 | 9513 | -0.067 | 0.0512 | No |
| 128 | Psmc6 | 9568 | -0.069 | 0.0494 | No |
| 129 | Mllt11 | 9629 | -0.072 | 0.0473 | No |
| 130 | Cdkn1a | 9910 | -0.084 | 0.0321 | No |
| 131 | Ddit3 | 9936 | -0.086 | 0.0323 | No |
| 132 | Plk1 | 9943 | -0.086 | 0.0338 | No |
| 133 | Polr3g | 9982 | -0.088 | 0.0333 | No |
| 134 | Pdap1 | 10040 | -0.090 | 0.0317 | No |
| 135 | Nmt1 | 10052 | -0.091 | 0.0329 | No |
| 136 | Sqstm1 | 10181 | -0.097 | 0.0272 | No |
| 137 | Elovl5 | 10200 | -0.097 | 0.0281 | No |
| 138 | Vldlr | 10403 | -0.108 | 0.0181 | No |
| 139 | Tbk1 | 10515 | -0.114 | 0.0137 | No |
| 140 | Rdh11 | 10553 | -0.116 | 0.0139 | No |
| 141 | Cops5 | 10577 | -0.117 | 0.0149 | No |
| 142 | Ppia | 10901 | -0.133 | -0.0019 | No |
| 143 | Ccng1 | 11039 | -0.140 | -0.0073 | No |
| 144 | Gsk3b | 11146 | -0.144 | -0.0107 | No |
| 145 | Mthfd2 | 11396 | -0.154 | -0.0226 | No |
| 146 | Adipor2 | 11488 | -0.160 | -0.0248 | No |
| 147 | Tcea1 | 11769 | -0.174 | -0.0382 | No |
| 148 | Sdf2l1 | 11901 | -0.181 | -0.0424 | No |
| 149 | Shmt2 | 11973 | -0.185 | -0.0428 | No |
| 150 | Prdx1 | 12088 | -0.190 | -0.0458 | No |
| 151 | Dapp1 | 12103 | -0.191 | -0.0427 | No |
| 152 | Hmgcr | 12113 | -0.191 | -0.0393 | No |
| 153 | Uchl5 | 12263 | -0.200 | -0.0442 | No |
| 154 | Fdxr | 12286 | -0.201 | -0.0413 | No |
| 155 | Eif2s2 | 12507 | -0.214 | -0.0502 | No |
| 156 | Ebp | 12520 | -0.215 | -0.0465 | No |
| 157 | Lta4h | 12676 | -0.225 | -0.0513 | No |
| 158 | Ufm1 | 12934 | -0.239 | -0.0619 | No |
| 159 | Fkbp2 | 12937 | -0.239 | -0.0571 | No |
| 160 | Wars1 | 13113 | -0.250 | -0.0625 | No |
| 161 | Ifi30 | 13690 | -0.288 | -0.0914 | No |
| 162 | Pno1 | 14036 | -0.310 | -0.1059 | No |
| 163 | Slc2a1 | 14095 | -0.313 | -0.1029 | No |
| 164 | Tpi1 | 14253 | -0.326 | -0.1057 | No |
| 165 | Ppa1 | 14308 | -0.331 | -0.1021 | No |
| 166 | Tm7sf2 | 14347 | -0.334 | -0.0975 | No |
| 167 | Cacybp | 14376 | -0.337 | -0.0922 | No |
| 168 | Egln3 | 14382 | -0.337 | -0.0855 | No |
| 169 | Sla | 14418 | -0.340 | -0.0806 | No |
| 170 | Pik3r3 | 14516 | -0.349 | -0.0792 | No |
| 171 | Cfp | 14644 | -0.360 | -0.0795 | No |
| 172 | Gga2 | 14693 | -0.364 | -0.0748 | No |
| 173 | Slc1a5 | 15000 | -0.393 | -0.0852 | No |
| 174 | G6pdx | 15078 | -0.400 | -0.0816 | No |
| 175 | Ldha | 15399 | -0.439 | -0.0919 | No |
| 176 | Psmb5 | 15554 | -0.456 | -0.0918 | No |
| 177 | Cxcr4 | 15737 | -0.486 | -0.0927 | No |
| 178 | Dhcr7 | 15799 | -0.496 | -0.0862 | No |
| 179 | Psph | 15808 | -0.498 | -0.0763 | No |
| 180 | Psma4 | 15814 | -0.499 | -0.0663 | No |
| 181 | Eef1e1 | 15926 | -0.523 | -0.0622 | No |
| 182 | Pgk1 | 16119 | -0.570 | -0.0620 | No |
| 183 | Tubg1 | 16186 | -0.591 | -0.0538 | No |
| 184 | Psmc2 | 16229 | -0.601 | -0.0439 | No |
| 185 | Pdk1 | 16268 | -0.613 | -0.0335 | No |
| 186 | Tuba4a | 16294 | -0.626 | -0.0220 | No |
| 187 | Tmem97 | 16340 | -0.647 | -0.0114 | No |
| 188 | Arpc5l | 16374 | -0.662 | 0.0003 | No |
| 189 | Coro1a | 16653 | -0.931 | 0.0028 | No |

