| Dataset | Basophil.Basophil_Pheno.cls #Group2_versus_Group3.Basophil_Pheno.cls #Group2_versus_Group3_repos |
| Phenotype | Basophil_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | 0.27620193 |
| Normalized Enrichment Score (NES) | 1.2049701 |
| Nominal p-value | 0.17171717 |
| FDR q-value | 0.7431421 |
| FWER p-Value | 0.933 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Slc1a4 | 132 | 0.704 | 0.0067 | Yes |
| 2 | Nfil3 | 146 | 0.695 | 0.0204 | Yes |
| 3 | Pnp | 183 | 0.669 | 0.0322 | Yes |
| 4 | Serp1 | 234 | 0.630 | 0.0423 | Yes |
| 5 | Hsp90b1 | 237 | 0.627 | 0.0552 | Yes |
| 6 | Idh1 | 238 | 0.627 | 0.0683 | Yes |
| 7 | Abcf2 | 257 | 0.621 | 0.0802 | Yes |
| 8 | Ppp1r15a | 265 | 0.618 | 0.0926 | Yes |
| 9 | Canx | 364 | 0.581 | 0.0988 | Yes |
| 10 | Ctsc | 376 | 0.576 | 0.1101 | Yes |
| 11 | Mcm4 | 471 | 0.546 | 0.1158 | Yes |
| 12 | Acsl3 | 513 | 0.536 | 0.1245 | Yes |
| 13 | Nfkbib | 535 | 0.530 | 0.1343 | Yes |
| 14 | Got1 | 555 | 0.524 | 0.1440 | Yes |
| 15 | Tfrc | 677 | 0.495 | 0.1470 | Yes |
| 16 | Niban1 | 719 | 0.486 | 0.1547 | Yes |
| 17 | Gclc | 737 | 0.483 | 0.1637 | Yes |
| 18 | Xbp1 | 755 | 0.480 | 0.1727 | Yes |
| 19 | Ifrd1 | 847 | 0.466 | 0.1769 | Yes |
| 20 | Lgmn | 859 | 0.463 | 0.1859 | Yes |
| 21 | Ero1a | 887 | 0.460 | 0.1938 | Yes |
| 22 | P4ha1 | 928 | 0.451 | 0.2008 | Yes |
| 23 | Asns | 1038 | 0.433 | 0.2032 | Yes |
| 24 | Calr | 1101 | 0.424 | 0.2083 | Yes |
| 25 | Cdc25a | 1104 | 0.424 | 0.2170 | Yes |
| 26 | Acaca | 1254 | 0.403 | 0.2164 | Yes |
| 27 | Map2k3 | 1295 | 0.397 | 0.2222 | Yes |
| 28 | Hspa4 | 1297 | 0.397 | 0.2305 | Yes |
| 29 | Hspa5 | 1372 | 0.388 | 0.2341 | Yes |
| 30 | Edem1 | 1389 | 0.386 | 0.2411 | Yes |
| 31 | Btg2 | 1430 | 0.381 | 0.2467 | Yes |
| 32 | Gpi1 | 1433 | 0.380 | 0.2545 | Yes |
| 33 | Stip1 | 1435 | 0.380 | 0.2623 | Yes |
| 34 | Cd9 | 1582 | 0.364 | 0.2611 | Yes |
| 35 | Itgb2 | 1781 | 0.342 | 0.2562 | Yes |
| 36 | Rpn1 | 1827 | 0.336 | 0.2605 | Yes |
| 37 | Txnrd1 | 1832 | 0.336 | 0.2673 | Yes |
| 38 | Hk2 | 1928 | 0.327 | 0.2683 | Yes |
| 39 | Nupr1 | 2096 | 0.313 | 0.2648 | Yes |
| 40 | Gsr | 2190 | 0.305 | 0.2655 | Yes |
| 41 | Psmc4 | 2222 | 0.304 | 0.2699 | Yes |
| 42 | Aldoa | 2298 | 0.298 | 0.2716 | Yes |
| 43 | Hmbs | 2325 | 0.295 | 0.2762 | Yes |
| 44 | Bhlhe40 | 2449 | 0.287 | 0.2747 | No |
| 45 | Rit1 | 2751 | 0.264 | 0.2620 | No |
| 46 | Sc5d | 2913 | 0.252 | 0.2575 | No |
| 47 | Actr3 | 2945 | 0.249 | 0.2608 | No |
| 48 | Immt | 3079 | 0.240 | 0.2578 | No |
| 49 | Ssr1 | 3102 | 0.239 | 0.2614 | No |
| 50 | Etf1 | 3141 | 0.237 | 0.2640 | No |
| 51 | Acly | 3212 | 0.233 | 0.2646 | No |
| 52 | Cyb5b | 3255 | 0.230 | 0.2669 | No |
| 53 | Hspa9 | 3344 | 0.224 | 0.2662 | No |
| 54 | Ddit4 | 3349 | 0.224 | 0.2706 | No |
| 55 | Nufip1 | 3395 | 0.221 | 0.2725 | No |
| 56 | Shmt2 | 3644 | 0.205 | 0.2618 | No |
| 57 | Actr2 | 3689 | 0.202 | 0.2633 | No |
| 58 | Ube2d3 | 3730 | 0.200 | 0.2651 | No |
| 59 | Cct6a | 3974 | 0.188 | 0.2543 | No |
| 60 | Phgdh | 3997 | 0.186 | 0.2568 | No |
| 61 | Slc2a3 | 4012 | 0.185 | 0.2599 | No |
| 62 | Eno1b | 4304 | 0.169 | 0.2457 | No |
| 63 | Sytl2 | 4389 | 0.166 | 0.2441 | No |
| 64 | Rpa1 | 4575 | 0.155 | 0.2361 | No |
| 65 | M6pr | 4634 | 0.153 | 0.2358 | No |
| 66 | Rrp9 | 4699 | 0.149 | 0.2350 | No |
| 67 | Pgk1 | 4867 | 0.140 | 0.2278 | No |
| 68 | Pitpnb | 4961 | 0.136 | 0.2250 | No |
| 69 | Slc37a4 | 5169 | 0.126 | 0.2151 | No |
| 70 | Cdkn1a | 5296 | 0.119 | 0.2100 | No |
| 71 | Rab1a | 5397 | 0.113 | 0.2063 | No |
| 72 | Ccng1 | 5432 | 0.112 | 0.2066 | No |
| 73 | Elovl6 | 5434 | 0.112 | 0.2088 | No |
| 74 | Nfyc | 5630 | 0.101 | 0.1991 | No |
| 75 | Ykt6 | 5711 | 0.097 | 0.1963 | No |
| 76 | Mcm2 | 5900 | 0.089 | 0.1868 | No |
| 77 | Psmd14 | 5909 | 0.088 | 0.1881 | No |
| 78 | Hspd1 | 6007 | 0.083 | 0.1840 | No |
| 79 | Uso1 | 6081 | 0.080 | 0.1812 | No |
| 80 | Tbk1 | 6460 | 0.063 | 0.1596 | No |
| 81 | Atp2a2 | 6519 | 0.061 | 0.1574 | No |
| 82 | Pno1 | 6571 | 0.058 | 0.1555 | No |
| 83 | Srd5a1 | 6601 | 0.057 | 0.1549 | No |
| 84 | Ppia | 7035 | 0.037 | 0.1295 | No |
| 85 | Add3 | 7045 | 0.036 | 0.1297 | No |
| 86 | Hmgcs1 | 7058 | 0.035 | 0.1297 | No |
| 87 | Fdxr | 7112 | 0.033 | 0.1272 | No |
| 88 | Psmg1 | 7144 | 0.032 | 0.1260 | No |
| 89 | Skap2 | 7282 | 0.026 | 0.1182 | No |
| 90 | Slc6a6 | 7503 | 0.016 | 0.1052 | No |
| 91 | Psma3 | 7552 | 0.014 | 0.1026 | No |
| 92 | Tcea1 | 7570 | 0.014 | 0.1019 | No |
| 93 | Rrm2 | 7733 | 0.006 | 0.0922 | No |
| 94 | Cth | 7998 | -0.005 | 0.0763 | No |
| 95 | Atp6v1d | 8009 | -0.005 | 0.0758 | No |
| 96 | Ddit3 | 8041 | -0.006 | 0.0740 | No |
| 97 | G6pdx | 8056 | -0.007 | 0.0733 | No |
| 98 | Stard4 | 8104 | -0.009 | 0.0707 | No |
| 99 | Fgl2 | 8257 | -0.017 | 0.0618 | No |
| 100 | Tomm40 | 8767 | -0.039 | 0.0318 | No |
| 101 | Sla | 8788 | -0.041 | 0.0315 | No |
| 102 | Eif2s2 | 8874 | -0.046 | 0.0273 | No |
| 103 | Sec11a | 8894 | -0.046 | 0.0271 | No |
| 104 | Cyp51 | 8935 | -0.048 | 0.0257 | No |
| 105 | Slc1a5 | 9013 | -0.052 | 0.0221 | No |
| 106 | Fads2 | 9045 | -0.053 | 0.0213 | No |
| 107 | Vldlr | 9153 | -0.058 | 0.0160 | No |
| 108 | Nampt | 9204 | -0.061 | 0.0143 | No |
| 109 | Mllt11 | 9208 | -0.061 | 0.0154 | No |
| 110 | Cops5 | 9399 | -0.068 | 0.0053 | No |
| 111 | Adipor2 | 9467 | -0.070 | 0.0027 | No |
| 112 | Bcat1 | 9578 | -0.076 | -0.0024 | No |
| 113 | Idi1 | 9634 | -0.078 | -0.0041 | No |
| 114 | Pdap1 | 9694 | -0.081 | -0.0060 | No |
| 115 | Dapp1 | 9791 | -0.085 | -0.0100 | No |
| 116 | Nup205 | 9828 | -0.087 | -0.0104 | No |
| 117 | Pdk1 | 9978 | -0.093 | -0.0175 | No |
| 118 | Sord | 10195 | -0.102 | -0.0284 | No |
| 119 | Lta4h | 10213 | -0.103 | -0.0273 | No |
| 120 | Sqstm1 | 10238 | -0.104 | -0.0266 | No |
| 121 | Nmt1 | 10250 | -0.104 | -0.0251 | No |
| 122 | Tes | 10276 | -0.105 | -0.0244 | No |
| 123 | Psma4 | 10386 | -0.111 | -0.0287 | No |
| 124 | Cxcr4 | 10431 | -0.113 | -0.0290 | No |
| 125 | Fads1 | 10449 | -0.114 | -0.0277 | No |
| 126 | Ldlr | 10501 | -0.117 | -0.0283 | No |
| 127 | Gtf2h1 | 10618 | -0.122 | -0.0328 | No |
| 128 | Ufm1 | 10648 | -0.124 | -0.0320 | No |
| 129 | Dhcr24 | 10682 | -0.125 | -0.0314 | No |
| 130 | Psph | 10740 | -0.128 | -0.0322 | No |
| 131 | Psmc2 | 10798 | -0.130 | -0.0329 | No |
| 132 | Cacybp | 11008 | -0.141 | -0.0426 | No |
| 133 | Ldha | 11228 | -0.151 | -0.0527 | No |
| 134 | Pfkl | 11272 | -0.153 | -0.0522 | No |
| 135 | Dhfr | 11318 | -0.155 | -0.0516 | No |
| 136 | Fkbp2 | 11332 | -0.156 | -0.0492 | No |
| 137 | Slc7a11 | 11537 | -0.168 | -0.0580 | No |
| 138 | Glrx | 11626 | -0.172 | -0.0598 | No |
| 139 | Uchl5 | 11827 | -0.182 | -0.0681 | No |
| 140 | Pik3r3 | 11948 | -0.188 | -0.0714 | No |
| 141 | Ddx39a | 12031 | -0.192 | -0.0724 | No |
| 142 | Gmps | 12057 | -0.194 | -0.0699 | No |
| 143 | Mthfd2 | 12138 | -0.199 | -0.0706 | No |
| 144 | Psme3 | 12211 | -0.202 | -0.0707 | No |
| 145 | Hspe1 | 12228 | -0.202 | -0.0675 | No |
| 146 | Qdpr | 12252 | -0.204 | -0.0646 | No |
| 147 | Gsk3b | 12257 | -0.205 | -0.0606 | No |
| 148 | Psmc6 | 12357 | -0.210 | -0.0622 | No |
| 149 | Tmem97 | 12380 | -0.212 | -0.0591 | No |
| 150 | Ung | 12528 | -0.219 | -0.0635 | No |
| 151 | Tm7sf2 | 12587 | -0.222 | -0.0624 | No |
| 152 | Gla | 12697 | -0.229 | -0.0642 | No |
| 153 | Plk1 | 12816 | -0.237 | -0.0664 | No |
| 154 | Psat1 | 12840 | -0.238 | -0.0629 | No |
| 155 | Polr3g | 12987 | -0.247 | -0.0665 | No |
| 156 | Elovl5 | 13017 | -0.248 | -0.0631 | No |
| 157 | Aurka | 13217 | -0.262 | -0.0697 | No |
| 158 | Tubg1 | 13260 | -0.264 | -0.0668 | No |
| 159 | Prdx1 | 13455 | -0.278 | -0.0727 | No |
| 160 | Slc7a5 | 13484 | -0.279 | -0.0686 | No |
| 161 | Ebp | 13486 | -0.279 | -0.0628 | No |
| 162 | Psmd13 | 13654 | -0.292 | -0.0669 | No |
| 163 | Psmd12 | 13671 | -0.293 | -0.0617 | No |
| 164 | Ccnf | 13858 | -0.307 | -0.0666 | No |
| 165 | Rdh11 | 13869 | -0.308 | -0.0608 | No |
| 166 | Sdf2l1 | 13924 | -0.312 | -0.0576 | No |
| 167 | Gbe1 | 13994 | -0.318 | -0.0551 | No |
| 168 | Pgm1 | 14068 | -0.324 | -0.0528 | No |
| 169 | Egln3 | 14099 | -0.327 | -0.0478 | No |
| 170 | Cfp | 14122 | -0.330 | -0.0422 | No |
| 171 | Ak4 | 14131 | -0.331 | -0.0358 | No |
| 172 | Eef1e1 | 14313 | -0.346 | -0.0396 | No |
| 173 | Wars1 | 14551 | -0.367 | -0.0463 | No |
| 174 | Dhcr7 | 14832 | -0.389 | -0.0551 | No |
| 175 | Mthfd2l | 15071 | -0.415 | -0.0609 | No |
| 176 | Ifi30 | 15080 | -0.416 | -0.0527 | No |
| 177 | Insig1 | 15207 | -0.430 | -0.0514 | No |
| 178 | Plod2 | 15210 | -0.430 | -0.0425 | No |
| 179 | Tpi1 | 15465 | -0.462 | -0.0483 | No |
| 180 | Ppa1 | 15579 | -0.478 | -0.0452 | No |
| 181 | Coro1a | 15806 | -0.518 | -0.0480 | No |
| 182 | Arpc5l | 15885 | -0.530 | -0.0417 | No |
| 183 | Bub1 | 15917 | -0.536 | -0.0324 | No |
| 184 | Hmgcr | 16014 | -0.563 | -0.0265 | No |
| 185 | Psmb5 | 16132 | -0.591 | -0.0213 | No |
| 186 | Gga2 | 16250 | -0.621 | -0.0154 | No |
| 187 | Slc2a1 | 16294 | -0.638 | -0.0047 | No |
| 188 | Tuba4a | 16317 | -0.646 | 0.0074 | No |
| 189 | Sqle | 16501 | -0.752 | 0.0120 | No |

