| Dataset | Basophil.Basophil_Pheno.cls #Group2_versus_Group3.Basophil_Pheno.cls #Group2_versus_Group3_repos |
| Phenotype | Basophil_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | -0.2521666 |
| Normalized Enrichment Score (NES) | -0.88133657 |
| Nominal p-value | 0.5870842 |
| FDR q-value | 0.9538773 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Chek1 | 448 | 0.552 | -0.0135 | No |
| 2 | Mcm4 | 471 | 0.546 | -0.0014 | No |
| 3 | Tfrc | 677 | 0.495 | -0.0017 | No |
| 4 | Cdc25a | 1104 | 0.424 | -0.0170 | No |
| 5 | Lbr | 1187 | 0.411 | -0.0119 | No |
| 6 | Smc3 | 1207 | 0.409 | -0.0030 | No |
| 7 | Eif2s1 | 1238 | 0.404 | 0.0052 | No |
| 8 | Srsf1 | 1405 | 0.384 | 0.0046 | No |
| 9 | Rad21 | 1618 | 0.362 | 0.0007 | No |
| 10 | Lig1 | 1883 | 0.332 | -0.0072 | No |
| 11 | Cdc25b | 2032 | 0.319 | -0.0083 | No |
| 12 | Cdkn1b | 2553 | 0.278 | -0.0329 | No |
| 13 | Dctpp1 | 2588 | 0.275 | -0.0282 | No |
| 14 | Hnrnpd | 2625 | 0.272 | -0.0237 | No |
| 15 | Mcm6 | 2710 | 0.266 | -0.0223 | No |
| 16 | Mcm3 | 2718 | 0.265 | -0.0161 | No |
| 17 | Brms1l | 2842 | 0.257 | -0.0173 | No |
| 18 | Rbbp7 | 2948 | 0.249 | -0.0175 | No |
| 19 | Lmnb1 | 2980 | 0.248 | -0.0133 | No |
| 20 | Tcf19 | 3042 | 0.243 | -0.0110 | No |
| 21 | Syncrip | 3050 | 0.242 | -0.0054 | No |
| 22 | Cdkn2a | 3113 | 0.238 | -0.0033 | No |
| 23 | Msh2 | 3146 | 0.237 | 0.0006 | No |
| 24 | Dclre1b | 3156 | 0.236 | 0.0058 | No |
| 25 | Atad2 | 3633 | 0.205 | -0.0180 | No |
| 26 | Smc6 | 3657 | 0.204 | -0.0143 | No |
| 27 | Rad1 | 3782 | 0.198 | -0.0170 | No |
| 28 | Dnmt1 | 3947 | 0.190 | -0.0222 | No |
| 29 | Pnn | 4148 | 0.177 | -0.0300 | No |
| 30 | Anp32e | 4159 | 0.176 | -0.0263 | No |
| 31 | Lsm8 | 4461 | 0.162 | -0.0405 | No |
| 32 | Smc1a | 4550 | 0.156 | -0.0420 | No |
| 33 | Rpa1 | 4575 | 0.155 | -0.0396 | No |
| 34 | Shmt1 | 4691 | 0.150 | -0.0429 | No |
| 35 | Ipo7 | 4694 | 0.149 | -0.0393 | No |
| 36 | Dlgap5 | 4775 | 0.145 | -0.0406 | No |
| 37 | Mre11a | 4805 | 0.143 | -0.0388 | No |
| 38 | Mcm5 | 4922 | 0.138 | -0.0425 | No |
| 39 | Nup153 | 4932 | 0.137 | -0.0397 | No |
| 40 | Rpa2 | 4949 | 0.136 | -0.0373 | No |
| 41 | Donson | 5086 | 0.130 | -0.0423 | No |
| 42 | Zw10 | 5106 | 0.129 | -0.0403 | No |
| 43 | Nolc1 | 5146 | 0.127 | -0.0395 | No |
| 44 | Hells | 5160 | 0.127 | -0.0372 | No |
| 45 | Prkdc | 5164 | 0.126 | -0.0342 | No |
| 46 | Cdkn1a | 5296 | 0.119 | -0.0393 | No |
| 47 | Stag1 | 5299 | 0.118 | -0.0365 | No |
| 48 | Ssrp1 | 5303 | 0.118 | -0.0337 | No |
| 49 | Wee1 | 5400 | 0.113 | -0.0368 | No |
| 50 | Ppm1d | 5446 | 0.111 | -0.0368 | No |
| 51 | Mad2l1 | 5457 | 0.110 | -0.0346 | No |
| 52 | Psmc3ip | 5755 | 0.095 | -0.0503 | No |
| 53 | Rad50 | 5769 | 0.095 | -0.0487 | No |
| 54 | Mcm2 | 5900 | 0.089 | -0.0544 | No |
| 55 | Xpo1 | 5937 | 0.087 | -0.0545 | No |
| 56 | Pole4 | 5986 | 0.084 | -0.0553 | No |
| 57 | Prps1 | 6009 | 0.083 | -0.0546 | No |
| 58 | Nap1l1 | 6303 | 0.071 | -0.0706 | No |
| 59 | Prdx4 | 6314 | 0.071 | -0.0695 | No |
| 60 | Nme1 | 6370 | 0.068 | -0.0711 | No |
| 61 | Mcm7 | 6495 | 0.062 | -0.0771 | No |
| 62 | Spag5 | 6540 | 0.060 | -0.0783 | No |
| 63 | Suv39h1 | 6674 | 0.053 | -0.0851 | No |
| 64 | Rfc1 | 6722 | 0.051 | -0.0867 | No |
| 65 | Rad51ap1 | 6794 | 0.047 | -0.0898 | No |
| 66 | Pcna | 6837 | 0.046 | -0.0912 | No |
| 67 | Tbrg4 | 6964 | 0.040 | -0.0979 | No |
| 68 | Pola2 | 7200 | 0.029 | -0.1114 | No |
| 69 | Ilf3 | 7358 | 0.022 | -0.1203 | No |
| 70 | Hmga1b | 7506 | 0.016 | -0.1289 | No |
| 71 | Rpa3 | 7549 | 0.014 | -0.1311 | No |
| 72 | Orc2 | 7607 | 0.012 | -0.1342 | No |
| 73 | Ing3 | 7690 | 0.008 | -0.1390 | No |
| 74 | Rrm2 | 7733 | 0.006 | -0.1414 | No |
| 75 | Usp1 | 7821 | 0.002 | -0.1466 | No |
| 76 | Rfc3 | 7925 | -0.001 | -0.1528 | No |
| 77 | Kif2c | 7931 | -0.001 | -0.1531 | No |
| 78 | Tipin | 7951 | -0.002 | -0.1542 | No |
| 79 | Lyar | 8114 | -0.010 | -0.1638 | No |
| 80 | Timeless | 8155 | -0.012 | -0.1659 | No |
| 81 | Slbp | 8240 | -0.016 | -0.1706 | No |
| 82 | Pa2g4 | 8914 | -0.047 | -0.2102 | No |
| 83 | Ak2 | 8989 | -0.050 | -0.2135 | No |
| 84 | Ccnb2 | 9082 | -0.055 | -0.2177 | No |
| 85 | Brca1 | 9154 | -0.058 | -0.2205 | No |
| 86 | Ubr7 | 9170 | -0.059 | -0.2200 | No |
| 87 | Wdr90 | 9203 | -0.061 | -0.2204 | No |
| 88 | Tra2b | 9282 | -0.063 | -0.2236 | No |
| 89 | Gins3 | 9373 | -0.066 | -0.2274 | No |
| 90 | Trip13 | 9394 | -0.067 | -0.2270 | No |
| 91 | Kif4 | 9462 | -0.070 | -0.2293 | No |
| 92 | Ranbp1 | 9473 | -0.071 | -0.2282 | No |
| 93 | Rnaseh2a | 9500 | -0.072 | -0.2280 | No |
| 94 | Ncapd2 | 9612 | -0.078 | -0.2328 | No |
| 95 | Cks2 | 9619 | -0.078 | -0.2312 | No |
| 96 | Cdkn2c | 9623 | -0.078 | -0.2295 | No |
| 97 | Mms22l | 9627 | -0.078 | -0.2277 | No |
| 98 | Pttg1 | 9714 | -0.082 | -0.2309 | No |
| 99 | Tmpo | 9756 | -0.084 | -0.2314 | No |
| 100 | Nup205 | 9828 | -0.087 | -0.2335 | No |
| 101 | Pold3 | 9940 | -0.092 | -0.2380 | No |
| 102 | Dut | 9962 | -0.093 | -0.2370 | No |
| 103 | Plk4 | 10019 | -0.095 | -0.2380 | No |
| 104 | Prim2 | 10061 | -0.097 | -0.2381 | No |
| 105 | Xrcc6 | 10073 | -0.097 | -0.2364 | No |
| 106 | Paics | 10085 | -0.098 | -0.2347 | No |
| 107 | Hmgb2 | 10098 | -0.098 | -0.2330 | No |
| 108 | Rad51c | 10187 | -0.102 | -0.2358 | No |
| 109 | Hus1 | 10258 | -0.104 | -0.2375 | No |
| 110 | Cbx5 | 10260 | -0.104 | -0.2350 | No |
| 111 | Mybl2 | 10281 | -0.105 | -0.2336 | No |
| 112 | Ccne1 | 10434 | -0.113 | -0.2400 | No |
| 113 | Cdca8 | 10503 | -0.117 | -0.2412 | No |
| 114 | Racgap1 | 10512 | -0.117 | -0.2388 | No |
| 115 | Luc7l3 | 10583 | -0.121 | -0.2401 | No |
| 116 | Psip1 | 10756 | -0.129 | -0.2473 | No |
| 117 | Cenpe | 10819 | -0.131 | -0.2479 | No |
| 118 | Nasp | 10878 | -0.134 | -0.2481 | No |
| 119 | Myc | 10930 | -0.136 | -0.2478 | No |
| 120 | Diaph3 | 11003 | -0.140 | -0.2487 | Yes |
| 121 | Cdk1 | 11054 | -0.143 | -0.2482 | Yes |
| 122 | Ran | 11070 | -0.143 | -0.2456 | Yes |
| 123 | Smc4 | 11106 | -0.145 | -0.2441 | Yes |
| 124 | Asf1b | 11193 | -0.149 | -0.2457 | Yes |
| 125 | E2f8 | 11215 | -0.150 | -0.2432 | Yes |
| 126 | Spc24 | 11316 | -0.155 | -0.2455 | Yes |
| 127 | Ctcf | 11323 | -0.156 | -0.2420 | Yes |
| 128 | H2az1 | 11392 | -0.159 | -0.2422 | Yes |
| 129 | Nup107 | 11414 | -0.160 | -0.2395 | Yes |
| 130 | Chek2 | 11486 | -0.164 | -0.2398 | Yes |
| 131 | Pan2 | 11575 | -0.170 | -0.2409 | Yes |
| 132 | Stmn1 | 11587 | -0.171 | -0.2374 | Yes |
| 133 | Top2a | 11594 | -0.171 | -0.2335 | Yes |
| 134 | Kif22 | 11734 | -0.179 | -0.2376 | Yes |
| 135 | Spc25 | 11848 | -0.183 | -0.2399 | Yes |
| 136 | Srsf2 | 12001 | -0.191 | -0.2444 | Yes |
| 137 | Ube2s | 12005 | -0.191 | -0.2399 | Yes |
| 138 | Ddx39a | 12031 | -0.192 | -0.2366 | Yes |
| 139 | Phf5a | 12112 | -0.197 | -0.2366 | Yes |
| 140 | Mthfd2 | 12138 | -0.199 | -0.2333 | Yes |
| 141 | Pds5b | 12272 | -0.205 | -0.2363 | Yes |
| 142 | Gspt1 | 12276 | -0.205 | -0.2314 | Yes |
| 143 | Gins4 | 12294 | -0.206 | -0.2273 | Yes |
| 144 | Kif18b | 12297 | -0.207 | -0.2224 | Yes |
| 145 | Ccp110 | 12391 | -0.212 | -0.2228 | Yes |
| 146 | Ung | 12528 | -0.219 | -0.2256 | Yes |
| 147 | Dek | 12591 | -0.222 | -0.2239 | Yes |
| 148 | Cdc20 | 12606 | -0.223 | -0.2193 | Yes |
| 149 | Cit | 12659 | -0.226 | -0.2168 | Yes |
| 150 | Nbn | 12682 | -0.228 | -0.2125 | Yes |
| 151 | Snrpb | 12693 | -0.229 | -0.2075 | Yes |
| 152 | Pole | 12721 | -0.230 | -0.2035 | Yes |
| 153 | Plk1 | 12816 | -0.237 | -0.2033 | Yes |
| 154 | Mlh1 | 12913 | -0.243 | -0.2032 | Yes |
| 155 | Cks1b | 13063 | -0.252 | -0.2060 | Yes |
| 156 | Aurkb | 13127 | -0.255 | -0.2035 | Yes |
| 157 | Exosc8 | 13128 | -0.255 | -0.1972 | Yes |
| 158 | Jpt1 | 13183 | -0.259 | -0.1941 | Yes |
| 159 | Cse1l | 13210 | -0.261 | -0.1893 | Yes |
| 160 | Aurka | 13217 | -0.262 | -0.1832 | Yes |
| 161 | Trp53 | 13240 | -0.263 | -0.1780 | Yes |
| 162 | Tubg1 | 13260 | -0.264 | -0.1727 | Yes |
| 163 | Espl1 | 13283 | -0.266 | -0.1675 | Yes |
| 164 | Bard1 | 13330 | -0.268 | -0.1636 | Yes |
| 165 | Tubb5 | 13528 | -0.283 | -0.1686 | Yes |
| 166 | Nudt21 | 13530 | -0.283 | -0.1617 | Yes |
| 167 | Cdca3 | 13632 | -0.290 | -0.1607 | Yes |
| 168 | Cnot9 | 13686 | -0.294 | -0.1566 | Yes |
| 169 | Cdkn3 | 13713 | -0.296 | -0.1509 | Yes |
| 170 | Ezh2 | 13716 | -0.297 | -0.1437 | Yes |
| 171 | Mki67 | 13747 | -0.299 | -0.1382 | Yes |
| 172 | Eed | 13799 | -0.303 | -0.1338 | Yes |
| 173 | Tacc3 | 13801 | -0.303 | -0.1264 | Yes |
| 174 | Ppp1r8 | 14070 | -0.325 | -0.1346 | Yes |
| 175 | Melk | 14168 | -0.334 | -0.1323 | Yes |
| 176 | Asf1a | 14176 | -0.335 | -0.1245 | Yes |
| 177 | Pold1 | 14344 | -0.349 | -0.1260 | Yes |
| 178 | Dscc1 | 14432 | -0.356 | -0.1225 | Yes |
| 179 | Nop56 | 14465 | -0.359 | -0.1156 | Yes |
| 180 | Hmmr | 14660 | -0.376 | -0.1181 | Yes |
| 181 | Depdc1a | 14858 | -0.392 | -0.1204 | Yes |
| 182 | Cdk4 | 14909 | -0.397 | -0.1136 | Yes |
| 183 | Rfc2 | 15033 | -0.411 | -0.1110 | Yes |
| 184 | Bub1b | 15089 | -0.417 | -0.1040 | Yes |
| 185 | Pold2 | 15156 | -0.425 | -0.0975 | Yes |
| 186 | Brca2 | 15237 | -0.434 | -0.0917 | Yes |
| 187 | Hmgb3 | 15362 | -0.451 | -0.0881 | Yes |
| 188 | Pms2 | 15520 | -0.469 | -0.0861 | Yes |
| 189 | Tk1 | 15609 | -0.482 | -0.0795 | Yes |
| 190 | Dck | 15976 | -0.552 | -0.0881 | Yes |
| 191 | Pop7 | 16114 | -0.586 | -0.0819 | Yes |
| 192 | Birc5 | 16161 | -0.599 | -0.0700 | Yes |
| 193 | Mxd3 | 16162 | -0.599 | -0.0552 | Yes |
| 194 | Ube2t | 16325 | -0.649 | -0.0491 | Yes |
| 195 | Orc6 | 16330 | -0.651 | -0.0333 | Yes |
| 196 | H2ax | 16417 | -0.700 | -0.0212 | Yes |
| 197 | Gins1 | 16457 | -0.721 | -0.0058 | Yes |
| 198 | Cenpm | 16588 | -0.828 | 0.0067 | Yes |

