Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Basophil.Basophil_Pheno.cls #Group1_versus_Group4.Basophil_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | Basophil_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_IL6_JAK_STAT3_SIGNALING |
| Enrichment Score (ES) | -0.34166455 |
| Normalized Enrichment Score (NES) | -1.34146 |
| Nominal p-value | 0.075630255 |
| FDR q-value | 0.33997944 |
| FWER p-Value | 0.748 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Jun | 327 | 0.644 | 0.0190 | No |
| 2 | Pf4 | 668 | 0.543 | 0.0312 | No |
| 3 | Myd88 | 1820 | 0.370 | -0.0158 | No |
| 4 | Itgb3 | 1843 | 0.367 | 0.0050 | No |
| 5 | Stam2 | 2299 | 0.327 | -0.0028 | No |
| 6 | Hax1 | 2358 | 0.322 | 0.0131 | No |
| 7 | Fas | 2884 | 0.281 | -0.0016 | No |
| 8 | Cd44 | 3188 | 0.260 | -0.0043 | No |
| 9 | Ccr1 | 3459 | 0.242 | -0.0060 | No |
| 10 | Cd38 | 3822 | 0.217 | -0.0147 | No |
| 11 | Il9r | 3998 | 0.206 | -0.0128 | No |
| 12 | Grb2 | 4559 | 0.173 | -0.0361 | No |
| 13 | Irf1 | 4745 | 0.162 | -0.0375 | No |
| 14 | Ptpn11 | 4847 | 0.157 | -0.0341 | No |
| 15 | Stat2 | 4893 | 0.154 | -0.0276 | No |
| 16 | Tnfrsf21 | 5138 | 0.140 | -0.0338 | No |
| 17 | Cd9 | 5185 | 0.138 | -0.0283 | No |
| 18 | Ifngr2 | 5244 | 0.134 | -0.0238 | No |
| 19 | Il3ra | 5427 | 0.125 | -0.0272 | No |
| 20 | Dntt | 5451 | 0.123 | -0.0212 | No |
| 21 | Tnfrsf1b | 5477 | 0.122 | -0.0154 | No |
| 22 | Il7 | 5588 | 0.116 | -0.0150 | No |
| 23 | Stat1 | 5870 | 0.103 | -0.0257 | No |
| 24 | Csf1 | 6134 | 0.089 | -0.0362 | No |
| 25 | Pik3r5 | 6737 | 0.057 | -0.0689 | No |
| 26 | Il15ra | 7037 | 0.042 | -0.0844 | No |
| 27 | Tlr2 | 7117 | 0.038 | -0.0868 | No |
| 28 | Bak1 | 7238 | 0.034 | -0.0920 | No |
| 29 | Tgfb1 | 7239 | 0.034 | -0.0900 | No |
| 30 | Ifnar1 | 7774 | 0.008 | -0.1217 | No |
| 31 | Acvr1b | 7794 | 0.006 | -0.1224 | No |
| 32 | Cd36 | 7928 | 0.000 | -0.1304 | No |
| 33 | Itga4 | 7991 | -0.000 | -0.1341 | No |
| 34 | Stat3 | 8381 | -0.020 | -0.1563 | No |
| 35 | Il4ra | 8916 | -0.046 | -0.1857 | No |
| 36 | Pim1 | 9747 | -0.091 | -0.2301 | No |
| 37 | Ptpn1 | 9811 | -0.094 | -0.2283 | No |
| 38 | Il17ra | 10044 | -0.104 | -0.2360 | No |
| 39 | Cbl | 10172 | -0.111 | -0.2369 | No |
| 40 | Hmox1 | 10389 | -0.122 | -0.2426 | No |
| 41 | Il1r1 | 10549 | -0.131 | -0.2443 | No |
| 42 | Ifngr1 | 10742 | -0.141 | -0.2473 | No |
| 43 | Il6 | 11559 | -0.185 | -0.2853 | No |
| 44 | Socs1 | 12118 | -0.215 | -0.3059 | No |
| 45 | Ltbr | 12159 | -0.217 | -0.2952 | No |
| 46 | Socs3 | 12910 | -0.261 | -0.3247 | Yes |
| 47 | Il17rb | 13103 | -0.274 | -0.3198 | Yes |
| 48 | Csf2ra | 13356 | -0.292 | -0.3174 | Yes |
| 49 | Ptpn2 | 13557 | -0.307 | -0.3109 | Yes |
| 50 | Il1r2 | 14069 | -0.341 | -0.3212 | Yes |
| 51 | Tnfrsf12a | 14084 | -0.343 | -0.3015 | Yes |
| 52 | Il18r1 | 14263 | -0.357 | -0.2907 | Yes |
| 53 | Irf9 | 14272 | -0.358 | -0.2697 | Yes |
| 54 | Ebi3 | 14402 | -0.372 | -0.2551 | Yes |
| 55 | Tyk2 | 14572 | -0.389 | -0.2419 | Yes |
| 56 | Il6st | 14793 | -0.408 | -0.2307 | Yes |
| 57 | Il10rb | 15437 | -0.486 | -0.2401 | Yes |
| 58 | Tnf | 15792 | -0.548 | -0.2285 | Yes |
| 59 | Ltb | 15890 | -0.562 | -0.2006 | Yes |
| 60 | Crlf2 | 16008 | -0.586 | -0.1724 | Yes |
| 61 | Tnfrsf1a | 16258 | -0.654 | -0.1481 | Yes |
| 62 | Map3k8 | 16317 | -0.673 | -0.1112 | Yes |
| 63 | Il12rb1 | 16369 | -0.701 | -0.0722 | Yes |
| 64 | Csf3r | 16445 | -0.743 | -0.0321 | Yes |
| 65 | Il2rg | 16512 | -0.787 | 0.0112 | Yes |
