| Dataset | Basophil.Basophil_Pheno.cls #Group1_versus_Group2.Basophil_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | Basophil_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | 0.1610195 |
| Normalized Enrichment Score (NES) | 0.71030396 |
| Nominal p-value | 0.90625 |
| FDR q-value | 0.9904879 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Slc7a11 | 121 | 0.717 | 0.0096 | Yes |
| 2 | Dhcr24 | 225 | 0.636 | 0.0184 | Yes |
| 3 | Ddx39a | 282 | 0.601 | 0.0292 | Yes |
| 4 | Bub1 | 314 | 0.584 | 0.0411 | Yes |
| 5 | Hmgcr | 328 | 0.578 | 0.0540 | Yes |
| 6 | Pgm1 | 341 | 0.575 | 0.0669 | Yes |
| 7 | Ldlr | 418 | 0.552 | 0.0754 | Yes |
| 8 | Dhcr7 | 500 | 0.529 | 0.0829 | Yes |
| 9 | Rrm2 | 624 | 0.497 | 0.0873 | Yes |
| 10 | Wars1 | 628 | 0.497 | 0.0988 | Yes |
| 11 | Ufm1 | 678 | 0.486 | 0.1073 | Yes |
| 12 | Slc7a5 | 713 | 0.477 | 0.1166 | Yes |
| 13 | Ppa1 | 782 | 0.466 | 0.1235 | Yes |
| 14 | Cyp51 | 830 | 0.459 | 0.1315 | Yes |
| 15 | Mthfd2 | 923 | 0.444 | 0.1364 | Yes |
| 16 | Fads1 | 1045 | 0.423 | 0.1391 | Yes |
| 17 | Pgk1 | 1106 | 0.415 | 0.1452 | Yes |
| 18 | Ccnf | 1310 | 0.389 | 0.1421 | Yes |
| 19 | Arpc5l | 1343 | 0.387 | 0.1494 | Yes |
| 20 | Tuba4a | 1476 | 0.371 | 0.1502 | Yes |
| 21 | Gla | 1510 | 0.368 | 0.1568 | Yes |
| 22 | Insig1 | 1582 | 0.359 | 0.1610 | Yes |
| 23 | Aurka | 1892 | 0.331 | 0.1501 | No |
| 24 | Slc2a1 | 1920 | 0.329 | 0.1563 | No |
| 25 | Psmb5 | 2318 | 0.297 | 0.1393 | No |
| 26 | Ebp | 2354 | 0.295 | 0.1441 | No |
| 27 | Coro1a | 2517 | 0.285 | 0.1410 | No |
| 28 | Fdxr | 2560 | 0.281 | 0.1451 | No |
| 29 | Ak4 | 2631 | 0.277 | 0.1474 | No |
| 30 | Vldlr | 2782 | 0.267 | 0.1447 | No |
| 31 | Plk1 | 2815 | 0.264 | 0.1490 | No |
| 32 | Gga2 | 2825 | 0.263 | 0.1547 | No |
| 33 | Mllt11 | 3193 | 0.241 | 0.1381 | No |
| 34 | Fgl2 | 3294 | 0.235 | 0.1376 | No |
| 35 | Tubg1 | 3303 | 0.235 | 0.1427 | No |
| 36 | Sytl2 | 3363 | 0.232 | 0.1446 | No |
| 37 | Pno1 | 3424 | 0.229 | 0.1464 | No |
| 38 | Tpi1 | 3514 | 0.222 | 0.1463 | No |
| 39 | Sqle | 3814 | 0.205 | 0.1330 | No |
| 40 | Calr | 4025 | 0.193 | 0.1248 | No |
| 41 | Mcm2 | 4027 | 0.192 | 0.1293 | No |
| 42 | Serp1 | 4071 | 0.190 | 0.1312 | No |
| 43 | Sdf2l1 | 4200 | 0.183 | 0.1278 | No |
| 44 | Psmc2 | 4265 | 0.179 | 0.1281 | No |
| 45 | Cfp | 4359 | 0.174 | 0.1266 | No |
| 46 | Actr3 | 4378 | 0.173 | 0.1296 | No |
| 47 | G6pdx | 4409 | 0.171 | 0.1318 | No |
| 48 | Gsk3b | 4468 | 0.168 | 0.1323 | No |
| 49 | Pik3r3 | 4537 | 0.165 | 0.1321 | No |
| 50 | Skap2 | 4564 | 0.163 | 0.1343 | No |
| 51 | Uso1 | 4578 | 0.162 | 0.1374 | No |
| 52 | Slc1a5 | 4587 | 0.162 | 0.1407 | No |
| 53 | Psmc6 | 4619 | 0.160 | 0.1426 | No |
| 54 | Plod2 | 4645 | 0.159 | 0.1449 | No |
| 55 | Ifrd1 | 4649 | 0.159 | 0.1485 | No |
| 56 | Rpn1 | 4825 | 0.149 | 0.1414 | No |
| 57 | Gtf2h1 | 4959 | 0.142 | 0.1367 | No |
| 58 | Rdh11 | 4981 | 0.141 | 0.1388 | No |
| 59 | Cxcr4 | 5086 | 0.137 | 0.1357 | No |
| 60 | Fkbp2 | 5195 | 0.132 | 0.1323 | No |
| 61 | Dhfr | 5230 | 0.130 | 0.1333 | No |
| 62 | Hspa5 | 5243 | 0.129 | 0.1356 | No |
| 63 | Lta4h | 5248 | 0.129 | 0.1384 | No |
| 64 | Actr2 | 5266 | 0.128 | 0.1404 | No |
| 65 | Adipor2 | 5289 | 0.127 | 0.1421 | No |
| 66 | Slc37a4 | 5360 | 0.124 | 0.1408 | No |
| 67 | Hk2 | 5522 | 0.116 | 0.1338 | No |
| 68 | Nfyc | 5632 | 0.113 | 0.1298 | No |
| 69 | Tomm40 | 5670 | 0.110 | 0.1302 | No |
| 70 | Pfkl | 5737 | 0.107 | 0.1287 | No |
| 71 | Sla | 5770 | 0.105 | 0.1293 | No |
| 72 | Uchl5 | 5844 | 0.102 | 0.1273 | No |
| 73 | Hsp90b1 | 5962 | 0.097 | 0.1225 | No |
| 74 | Cyb5b | 5971 | 0.097 | 0.1243 | No |
| 75 | Eef1e1 | 5978 | 0.096 | 0.1262 | No |
| 76 | Ero1a | 6003 | 0.095 | 0.1270 | No |
| 77 | Edem1 | 6089 | 0.091 | 0.1240 | No |
| 78 | Gbe1 | 6111 | 0.090 | 0.1249 | No |
| 79 | Immt | 6245 | 0.084 | 0.1188 | No |
| 80 | Tm7sf2 | 6274 | 0.083 | 0.1191 | No |
| 81 | Add3 | 6333 | 0.081 | 0.1174 | No |
| 82 | Psmd14 | 6398 | 0.078 | 0.1154 | No |
| 83 | Hmgcs1 | 6482 | 0.075 | 0.1121 | No |
| 84 | Pitpnb | 6776 | 0.062 | 0.0959 | No |
| 85 | Ppp1r15a | 6878 | 0.057 | 0.0911 | No |
| 86 | Cacybp | 7083 | 0.047 | 0.0799 | No |
| 87 | Psma4 | 7084 | 0.047 | 0.0810 | No |
| 88 | Canx | 7277 | 0.040 | 0.0703 | No |
| 89 | Elovl5 | 7404 | 0.035 | 0.0635 | No |
| 90 | Niban1 | 7543 | 0.029 | 0.0558 | No |
| 91 | Gsr | 7616 | 0.026 | 0.0520 | No |
| 92 | Polr3g | 7649 | 0.024 | 0.0507 | No |
| 93 | Pnp | 7736 | 0.020 | 0.0459 | No |
| 94 | Itgb2 | 7818 | 0.017 | 0.0414 | No |
| 95 | Atp2a2 | 7824 | 0.017 | 0.0415 | No |
| 96 | Nmt1 | 7885 | 0.015 | 0.0383 | No |
| 97 | Rab1a | 8128 | 0.004 | 0.0237 | No |
| 98 | Hspe1 | 8174 | 0.002 | 0.0210 | No |
| 99 | Ccng1 | 8180 | 0.002 | 0.0207 | No |
| 100 | Acly | 8302 | -0.001 | 0.0134 | No |
| 101 | Psme3 | 8506 | -0.010 | 0.0014 | No |
| 102 | Stip1 | 8526 | -0.011 | 0.0005 | No |
| 103 | Srd5a1 | 8562 | -0.013 | -0.0013 | No |
| 104 | Fads2 | 8608 | -0.014 | -0.0037 | No |
| 105 | Etf1 | 8677 | -0.017 | -0.0074 | No |
| 106 | Cdkn1a | 8707 | -0.018 | -0.0087 | No |
| 107 | Gmps | 8729 | -0.019 | -0.0095 | No |
| 108 | Rit1 | 8972 | -0.029 | -0.0235 | No |
| 109 | Ldha | 8989 | -0.030 | -0.0238 | No |
| 110 | Ssr1 | 9195 | -0.040 | -0.0353 | No |
| 111 | Elovl6 | 9202 | -0.040 | -0.0347 | No |
| 112 | Gpi1 | 9344 | -0.047 | -0.0421 | No |
| 113 | Phgdh | 9379 | -0.048 | -0.0430 | No |
| 114 | Prdx1 | 9382 | -0.048 | -0.0420 | No |
| 115 | Hspd1 | 9419 | -0.050 | -0.0430 | No |
| 116 | Pdap1 | 9476 | -0.053 | -0.0452 | No |
| 117 | Mcm4 | 9486 | -0.053 | -0.0444 | No |
| 118 | Hspa4 | 9802 | -0.068 | -0.0619 | No |
| 119 | Aldoa | 9855 | -0.071 | -0.0634 | No |
| 120 | Eno1b | 9860 | -0.071 | -0.0619 | No |
| 121 | Tes | 9928 | -0.075 | -0.0642 | No |
| 122 | Tbk1 | 10149 | -0.085 | -0.0755 | No |
| 123 | Glrx | 10294 | -0.091 | -0.0821 | No |
| 124 | Dapp1 | 10402 | -0.097 | -0.0863 | No |
| 125 | Ddit4 | 10447 | -0.099 | -0.0866 | No |
| 126 | Nufip1 | 10575 | -0.104 | -0.0918 | No |
| 127 | Nup205 | 10582 | -0.105 | -0.0897 | No |
| 128 | Cdc25a | 10872 | -0.118 | -0.1044 | No |
| 129 | Cd9 | 10968 | -0.122 | -0.1073 | No |
| 130 | Ifi30 | 10969 | -0.122 | -0.1044 | No |
| 131 | M6pr | 11157 | -0.133 | -0.1126 | No |
| 132 | Psma3 | 11206 | -0.135 | -0.1123 | No |
| 133 | Btg2 | 11348 | -0.142 | -0.1175 | No |
| 134 | Eif2s2 | 11389 | -0.144 | -0.1165 | No |
| 135 | Slc2a3 | 11422 | -0.146 | -0.1150 | No |
| 136 | Psmd13 | 11442 | -0.147 | -0.1127 | No |
| 137 | Psat1 | 11536 | -0.152 | -0.1147 | No |
| 138 | Cct6a | 11551 | -0.153 | -0.1120 | No |
| 139 | Stard4 | 11640 | -0.157 | -0.1136 | No |
| 140 | Idi1 | 11666 | -0.158 | -0.1114 | No |
| 141 | Sec11a | 11712 | -0.160 | -0.1103 | No |
| 142 | Psph | 11787 | -0.164 | -0.1109 | No |
| 143 | Qdpr | 11895 | -0.169 | -0.1134 | No |
| 144 | Nfkbib | 11938 | -0.171 | -0.1119 | No |
| 145 | Psmc4 | 12019 | -0.176 | -0.1126 | No |
| 146 | Rpa1 | 12234 | -0.187 | -0.1211 | No |
| 147 | Pdk1 | 12332 | -0.192 | -0.1225 | No |
| 148 | Sqstm1 | 12600 | -0.206 | -0.1337 | No |
| 149 | Egln3 | 12720 | -0.215 | -0.1359 | No |
| 150 | Ykt6 | 12805 | -0.220 | -0.1358 | No |
| 151 | Idh1 | 12819 | -0.221 | -0.1313 | No |
| 152 | Tcea1 | 12858 | -0.223 | -0.1284 | No |
| 153 | Xbp1 | 12905 | -0.226 | -0.1258 | No |
| 154 | Txnrd1 | 12911 | -0.227 | -0.1207 | No |
| 155 | Nfil3 | 12914 | -0.227 | -0.1155 | No |
| 156 | Bhlhe40 | 12954 | -0.230 | -0.1124 | No |
| 157 | Ppia | 12968 | -0.231 | -0.1077 | No |
| 158 | Cth | 12975 | -0.231 | -0.1026 | No |
| 159 | Gclc | 13064 | -0.236 | -0.1024 | No |
| 160 | Got1 | 13305 | -0.252 | -0.1110 | No |
| 161 | Hspa9 | 13487 | -0.267 | -0.1156 | No |
| 162 | Abcf2 | 13518 | -0.269 | -0.1111 | No |
| 163 | Rrp9 | 13566 | -0.273 | -0.1075 | No |
| 164 | Map2k3 | 13933 | -0.298 | -0.1226 | No |
| 165 | P4ha1 | 14058 | -0.308 | -0.1228 | No |
| 166 | Ube2d3 | 14211 | -0.321 | -0.1245 | No |
| 167 | Mthfd2l | 14249 | -0.324 | -0.1190 | No |
| 168 | Psmg1 | 14306 | -0.326 | -0.1147 | No |
| 169 | Ctsc | 14571 | -0.348 | -0.1225 | No |
| 170 | Nampt | 14673 | -0.355 | -0.1202 | No |
| 171 | Tmem97 | 14858 | -0.375 | -0.1225 | No |
| 172 | Slc6a6 | 15008 | -0.392 | -0.1223 | No |
| 173 | Psmd12 | 15078 | -0.398 | -0.1170 | No |
| 174 | Ddit3 | 15316 | -0.424 | -0.1213 | No |
| 175 | Cops5 | 15467 | -0.444 | -0.1199 | No |
| 176 | Bcat1 | 15676 | -0.476 | -0.1213 | No |
| 177 | Acaca | 15832 | -0.502 | -0.1188 | No |
| 178 | Slc1a4 | 15932 | -0.522 | -0.1124 | No |
| 179 | Ung | 16031 | -0.547 | -0.1054 | No |
| 180 | Lgmn | 16036 | -0.547 | -0.0927 | No |
| 181 | Sord | 16054 | -0.550 | -0.0808 | No |
| 182 | Sc5d | 16069 | -0.554 | -0.0685 | No |
| 183 | Asns | 16078 | -0.556 | -0.0559 | No |
| 184 | Atp6v1d | 16212 | -0.592 | -0.0499 | No |
| 185 | Shmt2 | 16223 | -0.596 | -0.0364 | No |
| 186 | Acsl3 | 16254 | -0.608 | -0.0239 | No |
| 187 | Tfrc | 16378 | -0.650 | -0.0160 | No |
| 188 | Nupr1 | 16447 | -0.685 | -0.0039 | No |
| 189 | Hmbs | 16597 | -0.807 | 0.0062 | No |

