| Dataset | Basophil.Basophil_Pheno.cls #Group1_versus_Group2.Basophil_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | Basophil_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.3793561 |
| Normalized Enrichment Score (NES) | 1.3783594 |
| Nominal p-value | 0.12676056 |
| FDR q-value | 0.75657374 |
| FWER p-Value | 0.699 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Asf1a | 214 | 0.643 | 0.0019 | Yes |
| 2 | Melk | 250 | 0.620 | 0.0141 | Yes |
| 3 | Ddx39a | 282 | 0.601 | 0.0261 | Yes |
| 4 | Nbn | 297 | 0.592 | 0.0390 | Yes |
| 5 | Asf1b | 377 | 0.565 | 0.0473 | Yes |
| 6 | Pole | 443 | 0.545 | 0.0559 | Yes |
| 7 | Cse1l | 536 | 0.520 | 0.0624 | Yes |
| 8 | Rrm2 | 624 | 0.497 | 0.0686 | Yes |
| 9 | Zw10 | 667 | 0.488 | 0.0773 | Yes |
| 10 | Hmmr | 669 | 0.487 | 0.0885 | Yes |
| 11 | Ccp110 | 675 | 0.486 | 0.0995 | Yes |
| 12 | Mlh1 | 679 | 0.484 | 0.1105 | Yes |
| 13 | Pds5b | 747 | 0.471 | 0.1173 | Yes |
| 14 | Cit | 832 | 0.459 | 0.1229 | Yes |
| 15 | Kif22 | 843 | 0.457 | 0.1328 | Yes |
| 16 | Pan2 | 844 | 0.456 | 0.1433 | Yes |
| 17 | Eed | 853 | 0.455 | 0.1534 | Yes |
| 18 | Mthfd2 | 923 | 0.444 | 0.1595 | Yes |
| 19 | Brca1 | 932 | 0.442 | 0.1692 | Yes |
| 20 | Depdc1a | 939 | 0.440 | 0.1790 | Yes |
| 21 | Racgap1 | 1117 | 0.413 | 0.1778 | Yes |
| 22 | Bub1b | 1187 | 0.404 | 0.1830 | Yes |
| 23 | Cnot9 | 1189 | 0.404 | 0.1923 | Yes |
| 24 | Mki67 | 1299 | 0.390 | 0.1947 | Yes |
| 25 | H2ax | 1436 | 0.377 | 0.1952 | Yes |
| 26 | Top2a | 1467 | 0.372 | 0.2020 | Yes |
| 27 | Cdk1 | 1508 | 0.368 | 0.2080 | Yes |
| 28 | Ccne1 | 1575 | 0.360 | 0.2124 | Yes |
| 29 | Nup107 | 1705 | 0.349 | 0.2126 | Yes |
| 30 | Cdkn2c | 1733 | 0.346 | 0.2190 | Yes |
| 31 | Aurka | 1892 | 0.331 | 0.2171 | Yes |
| 32 | Pold3 | 1895 | 0.331 | 0.2246 | Yes |
| 33 | Timeless | 1948 | 0.327 | 0.2290 | Yes |
| 34 | Brca2 | 2009 | 0.322 | 0.2328 | Yes |
| 35 | Aurkb | 2035 | 0.319 | 0.2387 | Yes |
| 36 | Espl1 | 2037 | 0.319 | 0.2460 | Yes |
| 37 | Cenpe | 2072 | 0.316 | 0.2512 | Yes |
| 38 | Tacc3 | 2089 | 0.315 | 0.2575 | Yes |
| 39 | Ubr7 | 2210 | 0.306 | 0.2574 | Yes |
| 40 | Hnrnpd | 2220 | 0.305 | 0.2639 | Yes |
| 41 | Pop7 | 2227 | 0.304 | 0.2705 | Yes |
| 42 | Donson | 2233 | 0.304 | 0.2773 | Yes |
| 43 | Mms22l | 2258 | 0.302 | 0.2828 | Yes |
| 44 | Cdca3 | 2263 | 0.301 | 0.2895 | Yes |
| 45 | Cdca8 | 2376 | 0.293 | 0.2895 | Yes |
| 46 | Kif18b | 2387 | 0.292 | 0.2956 | Yes |
| 47 | Pms2 | 2449 | 0.288 | 0.2986 | Yes |
| 48 | Gspt1 | 2457 | 0.288 | 0.3048 | Yes |
| 49 | Diaph3 | 2475 | 0.287 | 0.3104 | Yes |
| 50 | Lmnb1 | 2629 | 0.277 | 0.3076 | Yes |
| 51 | Anp32e | 2640 | 0.276 | 0.3133 | Yes |
| 52 | Tubb5 | 2735 | 0.270 | 0.3139 | Yes |
| 53 | Dlgap5 | 2771 | 0.268 | 0.3179 | Yes |
| 54 | Suv39h1 | 2779 | 0.267 | 0.3237 | Yes |
| 55 | Cdkn2a | 2786 | 0.267 | 0.3295 | Yes |
| 56 | Spag5 | 2800 | 0.266 | 0.3349 | Yes |
| 57 | Plk1 | 2815 | 0.264 | 0.3401 | Yes |
| 58 | Pcna | 2826 | 0.263 | 0.3456 | Yes |
| 59 | Srsf2 | 2838 | 0.263 | 0.3510 | Yes |
| 60 | Pold2 | 2849 | 0.262 | 0.3565 | Yes |
| 61 | Smc4 | 2911 | 0.258 | 0.3587 | Yes |
| 62 | Psmc3ip | 2997 | 0.253 | 0.3594 | Yes |
| 63 | Dek | 3022 | 0.252 | 0.3638 | Yes |
| 64 | Mcm7 | 3045 | 0.251 | 0.3683 | Yes |
| 65 | Nasp | 3261 | 0.238 | 0.3607 | Yes |
| 66 | Tubg1 | 3303 | 0.235 | 0.3637 | Yes |
| 67 | Dscc1 | 3375 | 0.232 | 0.3647 | Yes |
| 68 | Tmpo | 3661 | 0.213 | 0.3524 | Yes |
| 69 | Slbp | 3746 | 0.208 | 0.3521 | Yes |
| 70 | Rfc2 | 3843 | 0.203 | 0.3510 | Yes |
| 71 | Xpo1 | 3957 | 0.197 | 0.3487 | Yes |
| 72 | Dnmt1 | 3972 | 0.196 | 0.3524 | Yes |
| 73 | Bard1 | 4024 | 0.193 | 0.3537 | Yes |
| 74 | Mcm2 | 4027 | 0.192 | 0.3580 | Yes |
| 75 | Ppm1d | 4059 | 0.191 | 0.3606 | Yes |
| 76 | Dut | 4129 | 0.186 | 0.3607 | Yes |
| 77 | Pold1 | 4132 | 0.186 | 0.3649 | Yes |
| 78 | Ezh2 | 4183 | 0.184 | 0.3661 | Yes |
| 79 | Tcf19 | 4231 | 0.181 | 0.3675 | Yes |
| 80 | Nudt21 | 4250 | 0.180 | 0.3705 | Yes |
| 81 | Dck | 4254 | 0.180 | 0.3745 | Yes |
| 82 | Ncapd2 | 4319 | 0.177 | 0.3747 | Yes |
| 83 | Usp1 | 4430 | 0.169 | 0.3720 | Yes |
| 84 | E2f8 | 4481 | 0.167 | 0.3728 | Yes |
| 85 | Mre11a | 4530 | 0.165 | 0.3737 | Yes |
| 86 | Rad51ap1 | 4531 | 0.165 | 0.3776 | Yes |
| 87 | Lbr | 4595 | 0.161 | 0.3775 | Yes |
| 88 | Brms1l | 4626 | 0.160 | 0.3794 | Yes |
| 89 | Trp53 | 4730 | 0.154 | 0.3767 | No |
| 90 | Mybl2 | 4790 | 0.151 | 0.3766 | No |
| 91 | Myc | 4922 | 0.144 | 0.3720 | No |
| 92 | Atad2 | 4968 | 0.142 | 0.3725 | No |
| 93 | Prim2 | 5063 | 0.138 | 0.3700 | No |
| 94 | Smc1a | 5069 | 0.138 | 0.3729 | No |
| 95 | Rad51c | 5112 | 0.136 | 0.3735 | No |
| 96 | Mxd3 | 5114 | 0.136 | 0.3766 | No |
| 97 | Pola2 | 5240 | 0.129 | 0.3720 | No |
| 98 | Tra2b | 5263 | 0.128 | 0.3736 | No |
| 99 | Kif4 | 5292 | 0.127 | 0.3749 | No |
| 100 | Wdr90 | 5325 | 0.125 | 0.3758 | No |
| 101 | Kif2c | 5439 | 0.120 | 0.3718 | No |
| 102 | Hmgb2 | 5474 | 0.118 | 0.3724 | No |
| 103 | Mad2l1 | 5662 | 0.111 | 0.3637 | No |
| 104 | Syncrip | 5690 | 0.109 | 0.3646 | No |
| 105 | Hmgb3 | 5702 | 0.109 | 0.3664 | No |
| 106 | Ctcf | 5852 | 0.102 | 0.3597 | No |
| 107 | Msh2 | 5859 | 0.101 | 0.3617 | No |
| 108 | Luc7l3 | 5905 | 0.099 | 0.3613 | No |
| 109 | Cbx5 | 6244 | 0.084 | 0.3428 | No |
| 110 | Cks2 | 6268 | 0.083 | 0.3433 | No |
| 111 | Rfc1 | 6291 | 0.082 | 0.3439 | No |
| 112 | H2az1 | 6306 | 0.082 | 0.3449 | No |
| 113 | Nup153 | 6361 | 0.079 | 0.3435 | No |
| 114 | Cks1b | 6364 | 0.079 | 0.3452 | No |
| 115 | Ppp1r8 | 6366 | 0.079 | 0.3469 | No |
| 116 | Wee1 | 6473 | 0.075 | 0.3422 | No |
| 117 | Ilf3 | 6540 | 0.072 | 0.3399 | No |
| 118 | Gins3 | 6548 | 0.072 | 0.3412 | No |
| 119 | Nop56 | 6635 | 0.068 | 0.3375 | No |
| 120 | Cdk4 | 6816 | 0.060 | 0.3280 | No |
| 121 | Psip1 | 6846 | 0.059 | 0.3276 | No |
| 122 | Jpt1 | 6852 | 0.059 | 0.3287 | No |
| 123 | Ak2 | 6884 | 0.057 | 0.3281 | No |
| 124 | Rbbp7 | 6887 | 0.057 | 0.3293 | No |
| 125 | Tk1 | 7064 | 0.048 | 0.3198 | No |
| 126 | Birc5 | 7105 | 0.046 | 0.3184 | No |
| 127 | Lyar | 7182 | 0.043 | 0.3148 | No |
| 128 | Mcm3 | 7279 | 0.040 | 0.3099 | No |
| 129 | Nolc1 | 7403 | 0.035 | 0.3033 | No |
| 130 | Exosc8 | 7406 | 0.035 | 0.3039 | No |
| 131 | Cdc25b | 7408 | 0.035 | 0.3047 | No |
| 132 | Hells | 7447 | 0.033 | 0.3031 | No |
| 133 | Mcm6 | 7502 | 0.030 | 0.3006 | No |
| 134 | Rad21 | 7515 | 0.030 | 0.3005 | No |
| 135 | Stag1 | 7556 | 0.028 | 0.2987 | No |
| 136 | Tbrg4 | 7762 | 0.019 | 0.2868 | No |
| 137 | Gins1 | 7869 | 0.015 | 0.2807 | No |
| 138 | Ccnb2 | 7994 | 0.010 | 0.2734 | No |
| 139 | Xrcc6 | 8014 | 0.009 | 0.2725 | No |
| 140 | Prkdc | 8068 | 0.007 | 0.2694 | No |
| 141 | Spc25 | 8331 | -0.002 | 0.2536 | No |
| 142 | Pnn | 8349 | -0.003 | 0.2526 | No |
| 143 | Rnaseh2a | 8672 | -0.017 | 0.2335 | No |
| 144 | Cdkn1a | 8707 | -0.018 | 0.2319 | No |
| 145 | Dctpp1 | 8721 | -0.019 | 0.2315 | No |
| 146 | Prdx4 | 8781 | -0.021 | 0.2284 | No |
| 147 | Chek1 | 8952 | -0.028 | 0.2188 | No |
| 148 | Pa2g4 | 9134 | -0.037 | 0.2087 | No |
| 149 | Cenpm | 9219 | -0.040 | 0.2045 | No |
| 150 | Mcm4 | 9486 | -0.053 | 0.1896 | No |
| 151 | Stmn1 | 9517 | -0.055 | 0.1891 | No |
| 152 | Nap1l1 | 9537 | -0.056 | 0.1892 | No |
| 153 | Nme1 | 9613 | -0.059 | 0.1861 | No |
| 154 | Cdkn3 | 9714 | -0.064 | 0.1815 | No |
| 155 | Rad1 | 9947 | -0.076 | 0.1692 | No |
| 156 | Tipin | 10081 | -0.082 | 0.1630 | No |
| 157 | Rpa2 | 10246 | -0.089 | 0.1551 | No |
| 158 | Smc3 | 10304 | -0.092 | 0.1538 | No |
| 159 | Ipo7 | 10316 | -0.093 | 0.1553 | No |
| 160 | Plk4 | 10382 | -0.096 | 0.1535 | No |
| 161 | Smc6 | 10437 | -0.098 | 0.1525 | No |
| 162 | Trip13 | 10454 | -0.100 | 0.1539 | No |
| 163 | Ssrp1 | 10511 | -0.102 | 0.1528 | No |
| 164 | Nup205 | 10582 | -0.105 | 0.1510 | No |
| 165 | Rpa3 | 10731 | -0.112 | 0.1446 | No |
| 166 | Ube2t | 10788 | -0.116 | 0.1439 | No |
| 167 | Cdc25a | 10872 | -0.118 | 0.1416 | No |
| 168 | Orc2 | 11105 | -0.129 | 0.1305 | No |
| 169 | Pttg1 | 11106 | -0.129 | 0.1335 | No |
| 170 | Paics | 11401 | -0.145 | 0.1191 | No |
| 171 | Mcm5 | 11500 | -0.150 | 0.1166 | No |
| 172 | Rad50 | 11568 | -0.153 | 0.1161 | No |
| 173 | Orc6 | 11619 | -0.156 | 0.1167 | No |
| 174 | Chek2 | 11960 | -0.172 | 0.1000 | No |
| 175 | Gins4 | 11964 | -0.173 | 0.1038 | No |
| 176 | Prps1 | 11968 | -0.173 | 0.1077 | No |
| 177 | Eif2s1 | 11977 | -0.173 | 0.1112 | No |
| 178 | Ranbp1 | 12006 | -0.175 | 0.1136 | No |
| 179 | Rpa1 | 12234 | -0.187 | 0.1041 | No |
| 180 | Phf5a | 12302 | -0.191 | 0.1045 | No |
| 181 | Lig1 | 12334 | -0.193 | 0.1071 | No |
| 182 | Shmt1 | 12451 | -0.199 | 0.1046 | No |
| 183 | Snrpb | 13134 | -0.240 | 0.0689 | No |
| 184 | Dclre1b | 13370 | -0.258 | 0.0606 | No |
| 185 | Hmga1b | 13391 | -0.259 | 0.0654 | No |
| 186 | Ran | 13633 | -0.277 | 0.0572 | No |
| 187 | Cdkn1b | 13773 | -0.286 | 0.0553 | No |
| 188 | Hus1 | 13961 | -0.300 | 0.0509 | No |
| 189 | Lsm8 | 14364 | -0.331 | 0.0342 | No |
| 190 | Rfc3 | 14753 | -0.363 | 0.0191 | No |
| 191 | Spc24 | 15026 | -0.394 | 0.0117 | No |
| 192 | Srsf1 | 15252 | -0.415 | 0.0077 | No |
| 193 | Ube2s | 15372 | -0.431 | 0.0105 | No |
| 194 | Cdc20 | 15797 | -0.496 | -0.0038 | No |
| 195 | Ung | 16031 | -0.547 | -0.0052 | No |
| 196 | Ing3 | 16079 | -0.556 | 0.0048 | No |
| 197 | Tfrc | 16378 | -0.650 | 0.0017 | No |
| 198 | Pole4 | 16558 | -0.763 | 0.0085 | No |

