Category Term Count % PValue Genes List Total Pop Hits Pop Total Fold Enrichment Bonferroni Benjamini FDR GOTERM_MF_FAT GO:0004867~serine-type endopeptidase inhibitor activity 15 1.3392857142857142 5.44269401130392E-4 HMSD, SERPINB5, SERPINB8, SERPINB7, SERPINE1, SERPINB2, TFPI, SERPINB10, SERPINB11, SERPINB12, SERPINB4, SERPIND1, SERPINB13, SERPINB3, TFPI2 725 92 12983 2.9197151424287857 0.3762527450102173 0.3762527450102173 0.8409546944795343 GOTERM_MF_FAT GO:0060090~molecular adaptor activity 12 1.0714285714285714 0.0011037588203419862 CRKL, TP53BP2, BAIAP2L1, SORBS2, SLA2, CHN1, ABI2, OBSL1, SH2B2, SRC, SH3BP2, EPO 725 67 12983 3.2073288728769946 0.6161438523541771 0.38043874584846504 1.6985264267117328 GOTERM_MF_FAT GO:0004984~olfactory receptor activity 40 3.571428571428571 0.0019796465629076765 OR13G1, OR2AK2, OR2L8, OR1C1, OR2L5, OR2T2, OR6F1, OR2T1, OR2T4, OR2T3, OR2L3, OR2L13, OR2L2, OR2G3, OR2G2, OR2T10, OR2T11, OR2G6, OR2T12, OR2T5, OR2T33, OR2T6, OR2T35, OR2T34, OR2T8, OR2C3, OR14C36, OR2M7, OR2B11, OR11L1, OR2W5, OR2M2, OR2W3, OR2M3, OR2AE1, OR2M4, OR2M5, OR14A16, OR2T29, OR2T27, OR14I1 725 431 12983 1.6619569565565244 0.820585176080603 0.4359909044445507 3.0271440604129007 GOTERM_MF_FAT GO:0005248~voltage-gated sodium channel activity 5 0.4464285714285714 0.007988482949624062 SCN1A, SCN3A, SCN2A, SCN9A, SCN7A 725 15 12983 5.96919540229885 0.9990450266377554 0.8242085232755652 11.69879645407066 GOTERM_MF_FAT GO:0004866~endopeptidase inhibitor activity 16 1.4285714285714286 0.015297521828080292 HMSD, SERPINB5, SERPINB8, TNFAIP8, SERPINB7, SERPINE1, SERPINB2, TFPI, SERPINB10, SERPINB11, SERPINB12, SERPINB4, SERPIND1, SERPINB13, SERPINB3, TFPI2 725 145 12983 1.9760095124851367 0.9999984315821087 0.9309613393380073 21.268886644298323 GOTERM_MF_FAT GO:0005070~SH3/SH2 adaptor activity 8 0.7142857142857143 0.018142750887688623 CRKL, TP53BP2, SLA2, CHN1, ABI2, SH2B2, SRC, SH3BP2 725 49 12983 2.9236875439831103 0.9999998723795638 0.9290443955362189 24.724692411893457 GOTERM_MF_FAT GO:0005506~iron ion binding 27 2.410714285714286 0.02355330007703102 CYP3A4, FTMT, STEAP4, CYP3A5, CYP3A7, CYP51A1, CYP3A43, P4HA2, PLOD3, PGRMC2, MIOX, KDM3B, SCD5, PPP4C, AIFM3, CYB5A, CYP20A1, CYP4V2, CDO1, EIF2AK1, NDUFV2, AOX1, CYBRD1, KDM4C, STEAP2, STEAP1, SLC40A1 725 308 12983 1.569820868786386 0.9999999989400488 0.9477726506217244 30.90823993427151 GOTERM_MF_FAT GO:0030414~peptidase inhibitor activity 16 1.4285714285714286 0.023755948134930503 HMSD, SERPINB5, SERPINB8, TNFAIP8, SERPINB7, SERPINE1, SERPINB2, TFPI, SERPINB10, SERPINB11, SERPINB12, SERPINB4, SERPIND1, SERPINB13, SERPINB3, TFPI2 725 153 12983 1.8726887536623844 0.9999999991146123 0.9261429961522066 31.13033519031656 GOTERM_MF_FAT GO:0051082~unfolded protein binding 13 1.1607142857142858 0.02654439142982118 VBP1, AFG3L2, LMAN1, LRPAP1, DNAJC18, PPIC, SIL1, SCG5, HSPE1, DNAJB2, HSPD1, DNAJC2, HSPA9 725 115 12983 2.024335832083958 0.9999999999258513 0.9251044624009015 34.11933574561422 GOTERM_MF_FAT GO:0005198~structural molecule activity 48 4.285714285714286 0.027894684778012154 SEPT5, VAPA, LMNB1, CLDN5, COL3A1, PDLIM3, CLDN12, KLHL3, MYOT, MBP, MYL9, CLDN15, CRYBB1, DES, SORBS2, MAPT, TUBB6, ACTL6B, MYOM1, WNT6, TFPI2, CCDC108, ACTB, CTNNA1, EMILIN2, COL5A2, EPB41L3, ARPC1B, LAMA1, MUC3A, EPB41L1, MRPS18C, CDC42SE2, SPAG4, COL1A2, MAPK8IP2, MYH11, TUBA4A, MOSPD3, TUBA4B, RPL19P12, CRYBA2, CLTCL1, SEPT7, MATR3, CRYBA4, MUC17, ADD1 725 634 12983 1.3557793973675623 0.999999999977744 0.913951233587923 35.522721584272944 GOTERM_MF_FAT GO:0008093~cytoskeletal adaptor activity 4 0.35714285714285715 0.03246561721879019 BAIAP2L1, SORBS2, ABI2, OBSL1 725 13 12983 5.510026525198938 0.9999999999996261 0.9258259005863501 40.06856987758305 GOTERM_MF_FAT GO:0030554~adenyl nucleotide binding 105 9.375 0.03531259299910278 FASTKD1, ZAK, ITPKB, CLK1, TOP1, VPS4B, PMS2, RAPGEF4, TLK1, DHX35, PMS1, ABCB11, MYO3B, OLA1, PIM3, HNRNPU, NVL, NME5, MAPK1, EIF2AK1, ATP9B, MAPK3, CSNK1G3, SMARCA2, KIF26B, STK16, CLCN3, GAL3ST4, FGFR3, DNAH14, CHKB, NEK1, STK17B, BMPR2, EPHB4, SRC, UBE2D2, LMTK2, HSPE1, SMCHD1, TAOK2, MYO1B, AK3, ABCB1, AFG3L2, UBE2L3, ABCB6, ABCB4, EPHA4, PLK4, P2RX6, PSMC2, MYH11, GRK4, HSPD1, KIF22, STEAP4, HELQ, ZNF12, MOV10L1, MCM7, PEX1, ACTR5, ATP8B1, PMS2CL, CDK15, CDK14, AKT3, AIFM3, PI4KA, CDK6, NLRP3, KIF1A, TXNRD2, STEAP2, STEAP1, TOP3B, CETN1, AKAP9, ASNS, DNAH7, FMO5, CHD1L, SPEG, TGM2, MARS2, ACTL6B, CHD6, YES1, ACSL6, HSPA9, PDK1, ACTB, CPT1B, ACTC1, ALPK2, MAPK11, STRADB, MAPK12, AOX1, HSPA4L, JAK2, ABCC1, TSSK2, ABCC6, KIF20A 725 1577 12983 1.1923250169461879 0.9999999999999709 0.9255383729748842 42.746482089809 GOTERM_MF_FAT GO:0004707~MAP kinase activity 4 0.35714285714285715 0.03964950333463485 MAPK1, MAPK12, MAPK3, MAPK11 725 14 12983 5.116453201970443 0.9999999999999994 0.9326712576374246 46.61155782257863 GOTERM_MF_FAT GO:0004977~melanocortin receptor activity 3 0.26785714285714285 0.04009518587638619 MC2R, MC4R, MC5R 725 6 12983 8.953793103448275 0.9999999999999996 0.9206739295277402 46.99460675112015 GOTERM_MF_FAT GO:0001883~purine nucleoside binding 106 9.464285714285714 0.04074523431521979 FASTKD1, ZAK, ITPKB, CLK1, TOP1, VPS4B, PMS2, RAPGEF4, TLK1, DHX35, PMS1, ABCB11, MYO3B, OLA1, PIM3, HNRNPU, NVL, NME5, MAPK1, EIF2AK1, ATP9B, PDE5A, MAPK3, CSNK1G3, SMARCA2, KIF26B, STK16, CLCN3, GAL3ST4, FGFR3, DNAH14, CHKB, NEK1, STK17B, BMPR2, EPHB4, SRC, UBE2D2, LMTK2, HSPE1, SMCHD1, TAOK2, MYO1B, AK3, ABCB1, AFG3L2, UBE2L3, ABCB6, ABCB4, EPHA4, PLK4, P2RX6, PSMC2, MYH11, GRK4, HSPD1, KIF22, STEAP4, HELQ, ZNF12, MOV10L1, MCM7, PEX1, ACTR5, ATP8B1, PMS2CL, CDK15, CDK14, AKT3, AIFM3, PI4KA, CDK6, NLRP3, KIF1A, TXNRD2, STEAP2, STEAP1, TOP3B, CETN1, AKAP9, ASNS, DNAH7, FMO5, CHD1L, SPEG, TGM2, MARS2, ACTL6B, CHD6, YES1, ACSL6, HSPA9, PDK1, ACTB, CPT1B, ACTC1, ALPK2, MAPK11, STRADB, MAPK12, AOX1, HSPA4L, JAK2, ABCC1, TSSK2, ABCC6, KIF20A 725 1601 12983 1.1856365633547998 0.9999999999999998 0.9096801503750632 47.54869359080792 GOTERM_MF_FAT GO:0001882~nucleoside binding 106 9.464285714285714 0.04738265967600515 FASTKD1, ZAK, ITPKB, CLK1, TOP1, VPS4B, PMS2, RAPGEF4, TLK1, DHX35, PMS1, ABCB11, MYO3B, OLA1, PIM3, HNRNPU, NVL, NME5, MAPK1, EIF2AK1, ATP9B, PDE5A, MAPK3, CSNK1G3, SMARCA2, KIF26B, STK16, CLCN3, GAL3ST4, FGFR3, DNAH14, CHKB, NEK1, STK17B, BMPR2, EPHB4, SRC, UBE2D2, LMTK2, HSPE1, SMCHD1, TAOK2, MYO1B, AK3, ABCB1, AFG3L2, UBE2L3, ABCB6, ABCB4, EPHA4, PLK4, P2RX6, PSMC2, MYH11, GRK4, HSPD1, KIF22, STEAP4, HELQ, ZNF12, MOV10L1, MCM7, PEX1, ACTR5, ATP8B1, PMS2CL, CDK15, CDK14, AKT3, AIFM3, PI4KA, CDK6, NLRP3, KIF1A, TXNRD2, STEAP2, STEAP1, TOP3B, CETN1, AKAP9, ASNS, DNAH7, FMO5, CHD1L, SPEG, TGM2, MARS2, ACTL6B, CHD6, YES1, ACSL6, HSPA9, PDK1, ACTB, CPT1B, ACTC1, ALPK2, MAPK11, STRADB, MAPK12, AOX1, HSPA4L, JAK2, ABCC1, TSSK2, ABCC6, KIF20A 725 1612 12983 1.1775459912723538 1.0 0.927948126533925 52.904481993513826 GOTERM_MF_FAT GO:0019209~kinase activator activity 5 0.4464285714285714 0.047708370369673736 ALS2, CDK5R2, MAPK8IP2, MALT1, IL2 725 25 12983 3.58151724137931 1.0 0.9173451545466031 53.1536481109172 GOTERM_MF_FAT GO:0003774~motor activity 14 1.25 0.05361425076756111 KIF22, DNAH14, MYO1B, MYO3B, MYL12B, MYL12A, DNAH7, MYL9, KIF1A, SLC26A5, MYH11, DYNC1I2, KIF20A, KIF26B 725 142 12983 1.7655366682855755 1.0 0.9296466823373479 57.46314865237028 GOTERM_MF_FAT GO:0015377~cation:chloride symporter activity 3 0.26785714285714285 0.06951281566774131 SLC12A6, SLC12A9, SLC12A2 725 8 12983 6.7153448275862075 1.0 0.9626572788162446 67.29381891647253 GOTERM_MF_FAT GO:0017076~purine nucleotide binding 122 10.892857142857142 0.07332468892662398 SEPT5, FASTKD1, ZAK, ITPKB, CLK1, TOP1, VPS4B, PMS2, RAPGEF4, TLK1, DHX35, PMS1, ABCB11, MYO3B, OLA1, PIM3, HNRNPU, NVL, NME5, MAPK1, EIF2AK1, ATP9B, PDE5A, MAPK3, TUBA4A, RAB12, TUBA4B, CSNK1G3, SMARCA2, SEPT7, KIF26B, STK16, ADSS, CLCN3, GAL3ST4, FGFR3, DNAH14, NEK1, CHKB, STK17B, BMPR2, EPHB4, SRC, UBE2D2, RAC1, GMPPA, LMTK2, HSPE1, SMCHD1, TAOK2, MYO1B, AK3, ABCB1, DOCK8, AFG3L2, UBE2L3, ABCB6, ABCB4, EPHA4, PLK4, P2RX6, PSMC2, MYH11, GRK4, HSPD1, KIF22, STEAP4, HELQ, GTPBP10, ZNF12, MOV10L1, MCM7, PEX1, ACTR5, RASL10A, ATP8B1, TUBB6, PMS2CL, CDK15, AKT3, CDK14, AIFM3, RAB39B, PI4KA, CDK6, NLRP3, GNAL, KIF1A, TXNRD2, STEAP2, STEAP1, TOP3B, CETN1, AKAP9, ASNS, DNAH7, FMO5, CHD1L, SPEG, TGM2, MARS2, ACTL6B, SCG5, CHD6, YES1, ACSL6, HSPA9, ACTB, PDK1, CPT1B, ACTC1, ALPK2, MAPK11, STRADB, RAB31, MAPK12, AOX1, HSPA4L, TSSK2, JAK2, ABCC1, ABCC6, KIF20A 725 1918 12983 1.1390643989788214 1.0 0.9631607199138825 69.31157089930615 GOTERM_MF_FAT GO:0005524~ATP binding 96 8.571428571428571 0.07499333316066054 FASTKD1, ZAK, ITPKB, CLK1, TOP1, VPS4B, PMS2, TLK1, DHX35, PMS1, ABCB11, MYO3B, OLA1, PIM3, HNRNPU, NVL, NME5, MAPK1, EIF2AK1, ATP9B, MAPK3, CSNK1G3, SMARCA2, KIF26B, STK16, CLCN3, FGFR3, DNAH14, NEK1, CHKB, BMPR2, STK17B, EPHB4, SRC, UBE2D2, LMTK2, HSPE1, SMCHD1, TAOK2, MYO1B, AK3, ABCB1, AFG3L2, UBE2L3, ABCB6, ABCB4, EPHA4, PLK4, P2RX6, PSMC2, MYH11, GRK4, HSPD1, KIF22, HELQ, ZNF12, MOV10L1, MCM7, PEX1, ACTR5, ATP8B1, PMS2CL, CDK15, CDK14, AKT3, PI4KA, CDK6, NLRP3, KIF1A, TOP3B, AKAP9, CETN1, ASNS, DNAH7, CHD1L, SPEG, TGM2, ACTL6B, MARS2, CHD6, YES1, ACSL6, HSPA9, PDK1, ACTB, CPT1B, ACTC1, ALPK2, MAPK11, STRADB, MAPK12, HSPA4L, JAK2, TSSK2, ABCC1, KIF20A, ABCC6 725 1477 12983 1.1639324819648402 1.0 0.9599809770857232 70.15766438583586 GOTERM_MF_FAT GO:0008092~cytoskeletal protein binding 37 3.303571428571429 0.07669093202380727 ALDOA, ENAH, MAEA, PDLIM3, ABI2, ANLN, KLHL3, MYOT, TUBGCP6, NDE1, SORBS2, MAPT, OBSL1, GRID2IP, WIPF1, ACTC1, NF2, HTT, BAIAP2L1, MYO1B, FSCN1, MYO3B, SPIRE1, PTPRT, CTNNA1, CAPN2, ARPC1A, FMN1, EPB41L3, ARPC1B, PPP1R9A, EPB41L1, CAPN10, XIRP2, MAPK8IP2, MYH11, ADD1 725 504 12983 1.3146442255062947 1.0 0.9569115623125648 70.99600793551798 GOTERM_MF_FAT GO:0032559~adenyl ribonucleotide binding 97 8.660714285714285 0.07703354251430218 FASTKD1, ZAK, ITPKB, CLK1, TOP1, VPS4B, PMS2, TLK1, RAPGEF4, DHX35, PMS1, ABCB11, MYO3B, OLA1, PIM3, HNRNPU, NVL, NME5, MAPK1, EIF2AK1, ATP9B, MAPK3, CSNK1G3, SMARCA2, KIF26B, STK16, CLCN3, FGFR3, DNAH14, CHKB, NEK1, BMPR2, STK17B, EPHB4, SRC, UBE2D2, LMTK2, HSPE1, SMCHD1, TAOK2, MYO1B, AK3, ABCB1, AFG3L2, UBE2L3, ABCB6, ABCB4, EPHA4, PLK4, P2RX6, PSMC2, MYH11, GRK4, HSPD1, KIF22, HELQ, ZNF12, MOV10L1, MCM7, PEX1, ACTR5, ATP8B1, PMS2CL, CDK15, CDK14, AKT3, PI4KA, CDK6, NLRP3, KIF1A, TOP3B, CETN1, AKAP9, ASNS, DNAH7, CHD1L, SPEG, TGM2, ACTL6B, MARS2, CHD6, YES1, ACSL6, HSPA9, PDK1, ACTB, CPT1B, ACTC1, ALPK2, MAPK11, STRADB, MAPK12, HSPA4L, JAK2, ABCC1, TSSK2, ABCC6, KIF20A 725 1497 12983 1.1603445972404578 1.0 0.951285249805267 71.16250837413163 GOTERM_MF_FAT GO:0030674~protein binding, bridging 10 0.8928571428571428 0.07837206933403552 CRKL, TP53BP2, SLA2, FSCN1, COL1A2, CHN1, ABI2, SH2B2, SRC, SH3BP2 725 94 12983 1.9050623624358034 1.0 0.9475709415453452 71.80446744124849 GOTERM_MF_FAT GO:0005179~hormone activity 11 0.9821428571428571 0.07869030621423351 GRP, INSL4, RLN1, GHRH, RLN2, ADM2, INHA, INSL6, VGF, ADCYAP1, EPO 725 108 12983 1.823920817369093 1.0 0.9417108636923535 71.95511440618594 GOTERM_MF_FAT GO:0008307~structural constituent of muscle 6 0.5357142857142857 0.08263621561721127 SORBS2, MYH11, PDLIM3, MYOM1, MYOT, MYL9 725 42 12983 2.558226600985222 1.0 0.9436484152969902 73.76154929533601 GOTERM_MF_FAT GO:0030983~mismatched DNA binding 4 0.35714285714285715 0.08604904038077521 PMS2, ZNF12, PMS2CL, PMS1 725 19 12983 3.770018148820326 1.0 0.9443851614420733 75.23555243314107 GOTERM_MF_FAT GO:0008376~acetylgalactosaminyltransferase activity 5 0.4464285714285714 0.09162456334636833 GALNT3, CHSY3, GALNT7, CHPF, GALNTL6 725 31 12983 2.8883203559510564 1.0 0.9489827126414584 77.4781098547813